STAT3-IN-1

Catalog No.S0818

For research use only.

STAT3-IN-1 (compound 7d) is an excellent, selective and orally active inhibitor of STAT3 with IC50 of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 induces apoptosis of tumor cells.

STAT3-IN-1 Chemical Structure

CAS No. 2059952-75-7

Selleck's STAT3-IN-1 has been cited by 1 Publication

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Biological Activity

Description STAT3-IN-1 (compound 7d) is an excellent, selective and orally active inhibitor of STAT3 with IC50 of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 induces apoptosis of tumor cells.
Targets
STAT3 [1]
(in HT29 cells)
STAT3 [1]
(in MDA-MB 231 cells)
1.82 μM 2.14 μM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 475.53
Formula

C28H29NO6

CAS No. 2059952-75-7
Storage 3 years -20°C powder
2 years -80°C in solvent

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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