Sodium salicylate

Catalog No.S3137

For research use only.

Sodium salicylate is used in medicine as an analgesic and antipyretic.

Sodium salicylate Chemical Structure

CAS No. 54-21-7

Selleck's Sodium salicylate has been cited by 1 Publication

Purity & Quality Control

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Biological Activity

Description Sodium salicylate is used in medicine as an analgesic and antipyretic.
Targets
NF-κB [1]
In vitro

Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. [1] Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 32 mg/mL
(198.62 mM)
Water 32 mg/mL
(198.62 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 161.11
Formula

C7H6O3.Na

CAS No. 54-21-7
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

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