Sodium salicylate

Catalog No.S3137

Sodium salicylate Chemical Structure

Molecular Weight(MW): 161.11

Sodium salicylate is used in medicine as an analgesic and antipyretic.

Size Price Stock Quantity  
In DMSO USD 130 In stock
USD 97 In stock
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Biological Activity

Description Sodium salicylate is used in medicine as an analgesic and antipyretic.
Targets
NF-κB [1]
In vitro

Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. [1] Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. [2]

Protocol

Solubility (25°C)

In vitro DMSO 32 mg/mL (198.62 mM)
Water 32 mg/mL (198.62 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 161.11
Formula

C7H6O3.Na

CAS No. 54-21-7
Storage powder
in solvent
Synonyms N/A

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID