Chondroitin sulfate

Catalog No.S2416

Chondroitin sulfate Chemical Structure

Molecular Weight(MW): 489.45

Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.

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Biological Activity

Description Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight 489.45
Formula

C16H27NO14S

CAS No. 9007-28-7
Storage powder
in solvent
Synonyms N/A

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03463499 Recruiting Interstitial Cystitis Samsung Medical Center September 22 2017 Not Applicable
NCT03463499 Recruiting Interstitial Cystitis Samsung Medical Center September 22 2017 Not Applicable
NCT02830919 Recruiting Osteoarthritis of Knee Eurofarma Laboratorios S.A. November 2016 Phase 3
NCT02830919 Recruiting Osteoarthritis of Knee Eurofarma Laboratorios S.A. November 2016 Phase 3
NCT02079727 Completed Knee Osteoarthritis IBSA Institut Biochimique SA June 12 2014 Phase 3
NCT02079727 Completed Knee Osteoarthritis IBSA Institut Biochimique SA June 12 2014 Phase 3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID