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Ethyl caffeate NF-κB inhibitor

Cat.No.S5640

Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
Ethyl caffeate NF-κB inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 208.21

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Quality Control

Batch: S564001 DMSO]250 mg/mL]true]]]false]]]false Purity: 99.05%
99.05

Chemical Information, Storage & Stability

Molecular Weight 208.21 Formula

C11H12O4

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 102-37-4 -- Storage of Stock Solutions

Synonyms N/A Smiles CCOC(=O)C=CC1=CC(=C(C=C1)O)O

Solubility

In vitro
Batch:

DMSO : 250 mg/mL (1200.71 mM) Warmed with 50°C water bath; Ultrasonicated;
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Mechanism of Action

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