Staurosporine (AM-2282)

Name: Staurosporine (AM-2282)
Brand: Selleck Chemicals
SKU: S1421
Rating: 5 (97 reviews)

For research use only.

Catalog No.S1421 Synonyms: Antibiotic AM-2282, STS

97 publications

Staurosporine (AM-2282) Chemical Structure

CAS No. 62996-74-1

Staurosporine (AM-2282, Antibiotic AM-2282, STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.

Selleck's Staurosporine (AM-2282) has been cited by 97 publications

Cell, 2020, 182(3):685-712.e19

PubMed: 32645325 ( click the link to review the publication )

Cancer Discov, 2019, 10.1158/2159-8290.CD-19-0270

PubMed: 31578185 ( click the link to review the publication )

Gastroenterology, 2017, 153(5):1429-1443

PubMed: 28764929 ( click the link to review the publication )

Nat Commun, 2021, 12(1):3636

PubMed: 34140467 ( click the link to review the publication )

Cell Chem Biol, 2021, S2451-9456(21)00303-2

PubMed: 34216546 ( click the link to review the publication )

Front Cell Dev Biol, 2021, 9:698679

PubMed: 34195205 ( click the link to review the publication )

Eur J Med Chem, 2021, 211:113003

PubMed: 33248847 ( click the link to review the publication )

J Cell Physiol, 2021, 10.1002/jcp.30443

PubMed: 34018605 ( click the link to review the publication )

Molecules, 2021, 26(15)4549

PubMed: 34361708 ( click the link to review the publication )

Biochem Biophys Res Commun, 2021, 567:92-98

PubMed: 34146907 ( click the link to review the publication )

STAR Protoc, 2021, 2(2):100391

PubMed: 33778784 ( click the link to review the publication )

Cell Rep, 2021, 34(8):108767

PubMed: 33626342 ( click the link to review the publication )

J Immunother Cancer, 2021, 9(2)e001906

PubMed: 33526609 ( click the link to review the publication )

EMBO J, 2020, 39(5):e102608

PubMed: 31930741 ( click the link to review the publication )

Genes Dev, 2020, 34(7-8):526-543

PubMed: 32079652 ( click the link to review the publication )

Cell Rep, 2020, 10;30(10):3411-3423 e7

PubMed: 32160546 ( click the link to review the publication )

Cell Rep, 2020, 30(11):3864-3874

PubMed: 32187555 ( click the link to review the publication )

EBioMedicine, 2020, 51:102585

PubMed: 31879244 ( click the link to review the publication )

Sci Signal, 2020, 13(623)

PubMed: 32184287 ( click the link to review the publication )

Cancers (Basel), 2020, 12(9)E2668

PubMed: 32962010 ( click the link to review the publication )

Cancers (Basel), 2020, 10;12(6):E1523

PubMed: 32532053 ( click the link to review the publication )

Anal Chem, 2020, 92(1):1363-1371

PubMed: 31794197 ( click the link to review the publication )

Anal Chem, 2020, 10.1021/acs.analchem.0c02756

PubMed: 32933243 ( click the link to review the publication )

FASEB J, 2020, 34(1):1122-1135

PubMed: 31914633 ( click the link to review the publication )
Eur J Med Chem, 2020, 193:112232

PubMed: 32199135 ( click the link to review the publication )

Nephrol Dial Transplant, 2020, gfaa290

PubMed: 33367746 ( click the link to review the publication )

Eur J Immunol, 2020, 10.1002/eji.202048905

PubMed: 33354776 ( click the link to review the publication )

Int J Mol Sci, 2020, 18;21(8):2825

PubMed: 32325639 ( click the link to review the publication )

Sci Rep, 2020, 10(1):18677

PubMed: 33122816 ( click the link to review the publication )

Sci Rep, 2020, 10(1):931

PubMed: 31969633 ( click the link to review the publication )

Molecules, 2020, 25(18)E4318

PubMed: 32967084 ( click the link to review the publication )

Eur J Pharmacol, 2020, 868:172886

PubMed: 31866407 ( click the link to review the publication )

Neoplasia, 2020, 22(10):470-483

PubMed: 32818841 ( click the link to review the publication )

Cell Res, 2020, 1-13

PubMed: 32759968 ( click the link to review the publication )

Cell Rep, 2020, 32(4):107959

PubMed: 32726624 ( click the link to review the publication )

Oncogene, 2020, 10.1038/s41388-020-1382-5

PubMed: 32651460 ( click the link to review the publication )

Mol Cancer Ther, 2020, 19(2):637-649

PubMed: 31784455 ( click the link to review the publication )

Autophagy, 2019, 10.1080/15548627

PubMed: 31251111 ( click the link to review the publication )

Autophagy, 2019, 15(2):295-311

PubMed: 30176161 ( click the link to review the publication )

Br J Pharmacol, 2019, 176(22):4388-4401

PubMed: 30270436 ( click the link to review the publication )

Ther Adv Med Oncol, 2019, 11:1758835919891567

PubMed: 31839810 ( click the link to review the publication )

FASEB J, 2019, 33(8):9062-9074

PubMed: 31180722 ( click the link to review the publication )

Nephrol Dial Transplant, 2019, 34(6):934-941

PubMed: 30189026 ( click the link to review the publication )

Int J Biol Sci, 2019, 15(4):838-846

PubMed: 30906214 ( click the link to review the publication )

Int Immunopharmacol, 2019, 66:146-153

PubMed: 30453148 ( click the link to review the publication )

Methods Mol Biol, 2019, 2054:171-183

PubMed: 31482456 ( click the link to review the publication )

J Org Chem, 2019, 10.1021/acs.joc.9b02414

PubMed: 31858795 ( click the link to review the publication )

Cell Res, 2018, 28(8):833-854

PubMed: 30030520 ( click the link to review the publication )
Nat Commun, 2018, 9(1):4846

PubMed: 30451870 ( click the link to review the publication )

Oncogene, 2018, 37(30):4122-4136

PubMed: 29706657 ( click the link to review the publication )

Oncogene, 2018, 37(11):1485-1502

PubMed: 29321664 ( click the link to review the publication )

Arch Toxicol, 2018, 92(6):2119-2135

PubMed: 29589053 ( click the link to review the publication )

Biochem Pharmacol, 2018, 150:9-23

PubMed: 29338970 ( click the link to review the publication )

Acta Pharmacol Sin, 2018, 39(12):1902-1912

PubMed: 30038340 ( click the link to review the publication )

Analyst, 2018, 143(12):2908-2914

PubMed: 29808847 ( click the link to review the publication )

Mol Carcinog, 2018, 57(7):886-895

PubMed: 29566278 ( click the link to review the publication )

Phytomedicine, 2018, 40:148-157

PubMed: 29496167 ( click the link to review the publication )

Exp Cell Res, 2018, 370(1):103-115

PubMed: 29908160 ( click the link to review the publication )

Virus Res, 2018, 246:55-64

PubMed: 29341877 ( click the link to review the publication )

J Child Adolesc Psychopharmacol, 2018, 28(2):117-123

PubMed: 29161523 ( click the link to review the publication )

Oncotarget, 2018, 9(24):16917-16931

PubMed: 29682194 ( click the link to review the publication )

Oncotarget, 2018, 9(89):35962-35973

PubMed: 30542510 ( click the link to review the publication )

Oncotarget, 2018, 9(32):22254-22268

PubMed: 29854276 ( click the link to review the publication )

Nat Commun, 2017, 1;8(1):1232

PubMed: 29089541 ( click the link to review the publication )

EMBO J, 2017, 36(2):202-212

PubMed: 27852626 ( click the link to review the publication )

Cell Rep, 2017, 20(7):1692-1704

PubMed: 28813679 ( click the link to review the publication )

Anal Chem, 2017, 89(3):1892-1899

PubMed: 28208281 ( click the link to review the publication )

Mol Cancer Ther, 2017, 16(1):57-67

PubMed: 27760835 ( click the link to review the publication )

Mol Cancer Ther, 2017, 16(10):2201-2214

PubMed: 28619755 ( click the link to review the publication )

J Virol, 2017, 91(23)

PubMed: 28904196 ( click the link to review the publication )

Acta Pharmacol Sin, 2017, 38(12):1632-1641

PubMed: 28713162 ( click the link to review the publication )

J Agric Food Chem, 2017, 65(31):6625-6637

PubMed: 28697598 ( click the link to review the publication )
Virology, 2017, 505:91-101

PubMed: 28235685 ( click the link to review the publication )

SLAS Discov, 2017, 22(5):507-515

PubMed: 28324660 ( click the link to review the publication )

Oncotarget, 2017, 8(42):71512-71519

PubMed: 29069723 ( click the link to review the publication )

Eur J Med Chem, 2016, 124:583-607

PubMed: 27614407 ( click the link to review the publication )

Mol Pharm, 2016, 13(11):3724-3735

PubMed: 27653969 ( click the link to review the publication )

J Cancer Res Clin Oncol, 2016, 142(11):2263-73

PubMed: 27576506 ( click the link to review the publication )

PLoS One, 2016, 11(5):e0154932

PubMed: 27183222 ( click the link to review the publication )

Biochem Biophys Res Commun, 2016, 471(4):528-32

PubMed: 26879140 ( click the link to review the publication )

Exp Clin Endocrinol Diabetes, 2016, 1427:419-30

PubMed: 26849668 ( click the link to review the publication )

Oncotarget, 2016, 7(46):74987-74999

PubMed: 27602492 ( click the link to review the publication )

Oncotarget, 2016, 7(27):41488-41504

PubMed: 27166192 ( click the link to review the publication )

Methods Mol Biol, 2016, 1427:419-30

PubMed: 27259939 ( click the link to review the publication )

Mol Cancer, 2015, 14:114

PubMed: 26041471 ( click the link to review the publication )

Mol Cancer, 2015, 14:59

PubMed: 25880778 ( click the link to review the publication )

J Exp Clin Cancer Res, 2015, 34:69

PubMed: 26198850 ( click the link to review the publication )

Cancer Cell Int, 2015, 15:97

PubMed: 26464561 ( click the link to review the publication )

PLoS One, 2015, 10(3):e0119715

PubMed: 25790461 ( click the link to review the publication )

PLoS One, 2015, 10(7):e0134306

PubMed: 26218638 ( click the link to review the publication )

Cancer Res, 2014, 74(23):7090-102

PubMed: 25277525 ( click the link to review the publication )

Cell Rep, 2014, 8(4):1037-48

PubMed: 25127139 ( click the link to review the publication )

Cell Commun Signal, 2013, 11:76

PubMed: 24090154 ( click the link to review the publication )

Am J Physiol Cell Physiol, 2013, 304(9):C895-904

PubMed: 23447036 ( click the link to review the publication )

J Biomol Screen, 2013, 18(4):388-99

PubMed: 23134735 ( click the link to review the publication )

PLoS One, 2012, 7(6):e39679

PubMed: 22768106 ( click the link to review the publication )
J Biomol Screen, 2012, 17(6):813-21

PubMed: 22453235 ( click the link to review the publication )

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description

Targets

PKCα ^[1] (Cell-free assay)	c-Fgr ^[2] (Cell-free assay)	phosphorylase kinase ^[2] (Cell-free assay)	PKCη ^[1] (Cell-free assay)	PKCγ ^[1] (Cell-free assay)	View More
2 nM	2 nM	3 nM	4 nM	5 nM	View More

In vitro

Staurosporine, a microbial alkaloid, significantly inhibits protein kinase C from rat brain with IC50 of 2.7 nM. Staurosporine displays strong inhibitory effect against HeLa S3 cells with IC50 of 4 nM. ^[1] Staurosporine also inhibits a variety of other protein kinases, including PKA, PKG, phosphorylase kinase, S6 kinase, Myosin light chain kinase (MLCK), CAM PKII, cdc2, v-Src, Lyn, c-Fgr, and Syk with IC50 of 15 nM, 18 nM, 3 nM, 5 nM, 21 nM, 20 nM, 9 nM, 6 nM, 20 nM, 2 nM, and 16 nM, respectively. ^[2] Staurosporine (1 μM) induces >90% apoptosis in PC12 cells. Consistently, Staurosporine treatment induces a rapid and prolonged elevation of intracellular free calcium levels [Ca²⁺]_i, accumulation of mitochondrial reactive oxygen species (ROS), and subsequent mitochondrial dysfunction. ^[3] The apoptosis of MCF7 cells induced by Staurosporine can be enhanced by the expression of functional caspase-3 via caspase-8 activation and Bid cleavage. ^[4] Staurosporine treatment at 1 μM only partially inhibits IL-3-stimulated Bcl2 phosphorylation but completely blocks PKC-mediated Bcl2 phosphorylation. ^[5] Staurosporine induces apoptosis of human foreskin fibroblasts AG-1518, depending on the lysosomal cathepsins D mediated cytochrome c release and caspase activation. ^[6] In addition to activating the classical mitochondrial apoptosis pathway, Staurosporine triggers a novel intrinsic apoptosis pathway, relying on the activation of caspase-9 in the absence of Apaf-1. ^[7]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Activity Description	PMID
human colon carcinoma cell line HCT116	M1O3c2Z2dmO2aX;uJIF{e2G7			NVPZSI5NS2:wY3XueJJifGmxbjDy[ZF2cXKnZDDmc5Ih\3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4h[2:ub36gZ4Fz[2mwb33hJINmdGxibHnu[UBJS1RzMU[sJGlEPTB;NjDuUU4>	MknaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3M{ezOFUoRjF3NUO3N\|Q2RC:jPh?=
human PBMC	MmLjSpVv[3Srb36gZZN{[Xl?		MWSyOEBp	MWDTeZBxemW\|c3nvckBw\iCLTEKgdJJw\HWldHnvckBqdiCqdX3hckBRSk2FIHHmeIVzKDJ2IHjyd{BjgSCHTFnTRUwhUUN3ME2xOkBvVS5?	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV6NUC0Okc,OTh3OEWwOFY9N2F-
endothelial cells	NGqyepFHfW6ldHnvckBie3OjeR?=			M1zORWVn\mWldHn2[UBld3OnIHHnZYlve3RicHzhd41qdm:pZX6gZYN1cX[jdH;yJIFkfGm4aYT5JJN1cW23bHH0[YQh[nlicHjvdoJwdCCnc4TldkBqdiCnbnTveIhmdGmjbDDj[YxteyxiRVS1NEA:KDdwNTFOwG0v	MoSyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDdyOUC5OUc,QDdyOUC5OVww[T5?
Sf9 insect cells	NFfn[GFHfW6ldHnvckBie3OjeR?=			NHrUT2RKdmirYnn0bY9vKG:oIIDyc5RmcW5ia3nuZZNmKENqMUqxcYl5fHW{ZTDv[kBRU0NiYXzwbIEhLiCkZYThLUBmgHC{ZYPz[YQhcW5iU3[5JIlve2WldDDj[YxteyxiSVO1NEA:KDBwMEKg{txONg>?	NXu4WGk1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUi3N\|YxPSd-OUi3N\|YxPTxxYU6=
LoVo cells	NUiydpJuSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKGOxbH;uJINidmOncjDj[YxtKGyrbnWgLGxwXm9iY3XscJMqKHW\|aX7nJG1VXCCjc4PhfUwhUUN3MDC9JFAvODBzIN88UU4>	MnXEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
umbilical vein endothelial cells	NXL5[ZNKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			MWHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKHWvYnnsbYNidCC4ZXnuJIVv\G:2aHXsbYFtKGOnbHzzJEhJXV[HQ4OpJJV{cW6pIF3UWEBie3OjeTygTWM2OCB;IECuNFA1KM7:TT6=	MofvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
ST-486 cells	MkTzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?			M{iyNGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgZpVzc2m2IHz5cZBpd22jIHPlcIwhdGmwZTCoV3QuPDh4IHPlcIx{MSC3c3nu[{BOXFRiYYPzZZktKEmFNUCgQUAxNjByNzFOwG0v	MoiwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
DLD-1 cells	NEW0cXhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			NYqyeldxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubDDsbY5mKCiGTFStNUBk\WyuczmgeZNqdmdiTWTUJIF{e2G7LDDJR\|UxKD1iMD6wNFkh\|ryPLh?=	MlrWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
HEK293 cells	M{XVUmZ2dmO2aX;uJIF{e2G7			MkfnTY5pcWKrdHnvckBw\iCSS1OtZoV1[SCLSTDt[YRq[XSnZDDJUE05KHKnbHXhd4Uh\nKxbTDISWszQTNiY3XscJMh[nliRVzJV2EtKEmFNUCgQUAxNjB5NzFOwG0v	M2nWZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{OUSxN\|MyLz5zMkm0NVM{OTxxYU6=
P19 cells	M4jN[GZ2dmO2aX;uJIF{e2G7			MWrJcohq[mm2aX;uJI9nKFCuYYTlcIV1NWSncnn2[YQh\3Kxd4ToJIZi[3SxcjDy[YNmeHSxcjDpckBROTliY3XscJMtKEmFNUCgQUAxNjByMjFOwG0v	M17MPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	MYXGeY5kfGmxbjDhd5NigQ>?			NGi1d4hKdmirYnn0bY9vKG:oIGDsZZRmdGW2LXTldol3\WRiZ4Lve5RpKG[jY4TvdkBz\WOncITvdkBqdiCSMUmgZ4VtdHNuIFnDOVAhRSByLkCwNkDPxE1w	NGHWdmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	MYHGeY5kfGmxbjDhd5NigQ>?			NGrXNldKdmirYnn0bY9vKG:oIGDyc5RmcW5iS3nuZZNmKEFiaX6gVFE6KGOnbHzzMEBKSzVyIE2gNE4xODRizszNMi=>	NEHzepk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	MUTGeY5kfGmxbjDhd5NigQ>?			NVqye5l1UW6qaXLpeIlwdiCxZjDDZYxkcXWvL3PhcI1w\HWuaX6t[IVx\W6mZX70JJBzd3SnaX6gb4lv[XOnIIT5dIUhUUliaX6gVFE6KGOnbHzzMEBKSzVyIE2gNE4xODZizszNMi=>	NFq4TpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	NWPtbpRyTnWwY4Tpc44h[XO\|YYm=			Mlz6TY5pcWKrdHnvckBw\iCFeXPsbY4u\GWyZX7k[Y51KGurbnHz[UAyKGmwIGCxPUBk\WyuczygTWM2OCB;IECuNFA5KM7:TT6=	NVnxPGNjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
P19 cells	Mn:5SpVv[3Srb36gZZN{[Xl?			M{TKTmlvcGmkaYTpc44hd2ZiVnHzZ5Vt[XJiZX7kc5Rp\WyrYXyg[5Jwf3SqIH\hZ5RweiC{ZXPldJRweiCrbjDQNVkh[2WubIOsJGlEPTBiPTCwMlAyPCEQvF2u	NWTaRpI5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
HEK293 cells	NF6w[IVHfW6ldHnvckBie3OjeR?=			NHfoPXFKdmirYnn0bY9vKG:oIFnMMVghemWuZXHz[UBjgSCKRVuyPVMh[2WubIOg[ZhxemW\|c3nu[{BRU0NvYnX0ZVItKEmFNUCgQUAxNjB5NzFOwG0v	M3TGcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	MV;GeY5kfGmxbjDhd5NigQ>?			NXmxSppoUW6qaXLpeIlwdiCxZjDJcpN2dGmwIILlZ4VxfG:{IHvpcoF{\SCrbjDQNVkh[2WubIOsJGlEPTBiPTCwMlIh\|ryPLh?=	M4\XXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	MVzGeY5kfGmxbjDhd5NigQ>?			MV\Jcohq[mm2aX;uJI9nKEOjc3XpckBscW6jc3WgNUBqdiCSMUmgZ4VtdHNuIFnDOVAhRSBzLkSg{txONg>?	NUWxcYVHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
FL5.12-Akt1 cells	NX\QZXdYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			MV;BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IF\MOU4yOi2Da4SxJINmdGy\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvOjlizszNMi=>	M1X4TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NECzOlI3Lz5zNkSwN\|YzPjxxYU6=
MiaPaCa-2 cells	MYrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			M1TxVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgUYliWGGFYT2yJINmdGy\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvOzdizszNMi=>	NXm4eWgzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0NFM3OjZpPkG2OFA{PjJ4PD;hQi=>
FL5.12-Akt1 cells	NIH4PHNHfW6ldHnvckBie3OjeR?=			Mo\zRYN1cX[rdImgZYdicW6\|dDDHV2s{KGmwIF\MOU4yOi2Da4SxJINmdGy\|LDDFR\|UxKD1iMD60OkDPxE1w	MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRyM{[yOkc,OTZ2MEO2NlY9N2F-
MiaPaCa-2 cells	M1X1XmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MV\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2rYWDhR4EuOiClZXzsd{whUUN3MDC9JFAvOzdizszNMi=>	NX:2OGdiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0NVM4QDBpPkG2OFE{PzhyPD;hQi=>
FL5.12-Akt1 cells	M4nnZmZ2dmO2aX;uJIF{e2G7			M{flTWFkfGm4aYT5JIFo[Wmwc4SgS3NMOyCyaH;zdIhwenmuYYTpc44hcW5iRly1MlEzNUGtdEGgZ4VtdHNuIFXDOVAhRSByLkS2JO69VS5?	NFPK[JQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkSxN\|c5OCd-MU[0NVM4QDB:L3G+
Sf21 cells	MWXGeY5kfGmxbjDhd5NigQ>?			NW[z[FQyUW6qaXLpeIlwdiCxZjDKRWs{KGW6cILld5Nm\CCrbjDT[lIyKGOnbHzzMEBKSzVyIE2gNE4xODZizszNMi=>	MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzB6OEC1PUc,OTdyOEiwOVk9N2F-
U937 cells	MUXDfZRwfG:6aXPpeJkh[XO\|YYm=			NFK0NZlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQTN5IHPlcIx{NCCLQ{WwJF0hOiEQvF2u	NUHkNlVjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUewPFgxPjdpPkG3NFg5ODZ5PD;hQi=>
Sf9 cells	MUnGeY5kfGmxbjDhd5NigQ>?		NIP0ZogyKG2rbh?=	NEn2SoZKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFidX3vcE9NKEGWUDygTWM2OCB;IECuNFA2KM7:TT6=	M136UVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{G1PFU{Lz5zN{OxOVg2OzxxYU6=
Sf9 cells	MljHSpVv[3Srb36gZZN{[Xl?		MofXNlAhdWmwcx?=	MWnJcohq[mm2aX;uJI9nKGi3bXHuJGZ6diCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIFnfGW{IEKwJI1qdnNiYomgSWxKW0FiaX6gdJJme2WwY3Wgc4YhOSC3bX;sM2whSVSSLDDJR\|UxKD1iMD6wNVUh\|ryPLh?=	NEDDPGk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OxOVg2Oyd-MUezNVU5PTN:L3G+
Sf9 cells	MmfKSpVv[3Srb36gZZN{[Xl?		NIDkcYMyKG2rbh?=	M4TVTGlvcGmkaYTpc44hd2ZiaIXtZY4hTnmwIHX4dJJme3OnZDDpckBU\jliY3XscJMh[W[2ZYKgNUBucW5iYomgSWxKW0FiaX6gdJJme2WwY3Wgc4YhOTBidX3vcE9NKEGWUDygTWM2OCB;IECuNFM3KM7:TT6=	MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzNzNUi1N{c,OTd\|MUW4OVM9N2F-
Sf9 cells	MonXSpVv[3Srb36gZZN{[Xl?		MY[yNEBucW6\|	MoKxTY5pcWKrdHnvckBw\iCqdX3hckBHgW5iZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bi\nSncjCyNEBucW6\|IHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyIIXtc4wwVCCDVGCsJGlEPTBiPTCwMlA5OyEQvF2u	MlPNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
Sf9 cells	NIfzT4xHfW6ldHnvckBie3OjeR?=		MoTQNUBucW5?	NFL6TItKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyMDD1cY9tN0xiQWTQMEBKSzVyIE2gNE4zPyEQvF2u	NIrJSnM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OxOVg2Oyd-MUezNVU5PTN:L3G+
Sf9 cells	NFvSTnpHfW6ldHnvckBie3OjeR?=		NVfSTFZiOjBibXnudy=>	NX\YSmlSUW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAzOCCvaX7zJIJ6KEWOSWPBJIlvKHC{ZYPlcoNmKG:oIEGwNEB2dW:uL1ygRXRRNCCLQ{WwJF0hOC53MTFOwG0v	MkW2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
A549 cells	NF7XdVdEgXSxdH;4bYNqfHliYYPzZZk>		MVu3NkBp	NX;YNZZOS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBu\XSqb3SsJGdKPTBiPTCwMlAxOjRizszNMi=>	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR6NEe3OUc,OTh2OES3O\|U9N2F-
MDA-MB-231 cells	NF31b5lEgXSxdH;4bYNqfHliYYPzZZk>		MnntO\|IhcA>?	Ml3rR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB5MjDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCvZYToc4QtKEeLNUCgQUAxNjByN{Gg{txONg>?	M160clxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEi0O\|c2Lz5zOES4OFc4PTxxYU6=
HT29 cells	MofoR5l1d3SxeHnjbZR6KGG\|c3H5		MnvDO\|IhcA>?	MkT5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQzQSClZXzsd{Bi\nSncjC3NkBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDt[ZRpd2RuIFfJOVAhRSByLkCxNFkh\|ryPLh?=	NW\JUHE4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0PFQ4PzVpPkG4OFg1Pzd3PD;hQi=>
MCF7 cells	M365d2Z2dmO2aX;uJIF{e2G7			NHPr[3dKdmirYnn0bY9vKG:oIGDLRUBqdiCqdX3hckBOS0Z5IHPlcIx{KGK7IHHydoF6NWKjc3XkJIZtfW:{ZYPj[Y5k\SCjc4PhfUwhU2liPTCwMlAxPSEQvF2u	M4HhVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NkW2N\|Y6Lz5zOE[1OlM3QTxxYU6=
MCF7 cells	NVnHN2IzTnWwY4Tpc44h[XO\|YYm=			MmLOTY5pcWKrdHnvckBw\iCSS1GgbY4hcHWvYX6gUWNHPyClZXzsd{BjgSCjcoLhfU1j[XOnZDDmcJVwemW\|Y3XuZ4Uh[XO\|YYmsJGlEPTBiPTCyJO69VS5?	MlvmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NU[zOlkoRjF6NkW2N\|Y6RC:jPh?=
Sf9 cells	NHnteY1HfW6ldHnvckBie3OjeR?=			NWPyTHBiUW6qaXLpeIlwdiCxZjDoeY1idiCVeXug[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyxiSVO1NEA:KDBwMECzJO69VS5?	MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDh{M{e4OEc,OTh6MkO3PFQ9N2F-
Sf9 cells	MWjGeY5kfGmxbjDhd5NigQ>?			MonVTY5pcWKrdHnvckBw\iCqdX3hckBbSVB5MDDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{NCCLQ{WwJF0hOC5yNUOg{txONg>?	NFnWe3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEiyN\|c5PCd-MUi4NlM4QDR:L3G+
insect cells	NEH2T2pHfW6ldHnvckBie3OjeR?=			NEe1TYJKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IGDpcVEh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{BjgSCKVGLGMEBKSzVyIE2gNE4xOSEQvF2u	NXXwZZVGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmxO\|kxPzZpPkG5NVc6ODd4PD;hQi=>
HT-29 cells	NX:4SWN5SXCxcITvd4l{KGG\|c3H5		NFe5bVAzKGh?	Mm\wTY5lfWO2aX;uJI9nKGGyb4D0c5NqeyCrbjDoeY1idiCKVD2yPUBk\WyuczDhd5Nme3OnZDDhd{BkcGGwZ3WgbY4hdWm2b3Poc45lemmjbDD0doFve22nbXLyZY5mKHCxdHXueIlidCCjZoTldkAzKGi{czDifUBLSzFic4ThbY5qdmdiYnHz[YQh\my3b4Lld4NmdmOnIHHzd4F6NCCHREWwJF0hOC5yMEK2JO69VS5?	NYe2e5U3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlIzODZpPkG5OFIzOjB4PD;hQi=>
insect Sf21 cells	NWnLbGJNTnWwY4Tpc44h[XO\|YYm=			MoPNTY5pcWKrdHnvckBw\iCMQVuzJIV5eHKnc4Pl[EBqdiCrboPlZ5QhW2Z{MTDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKGKrb4Tpcplt[XSnZDDzeYJ{fHKjdHWgdIhwe3Cqb4L5cIF1cW:wLDDJR\|UxKD1iMD6wNFYh\|ryPLh?=	MnLLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkeyNFMoRjF7NEK3NlA{RC:jPh?=
Jurkat cells	M3jsWWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			NXLNfGx4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBLSUt\|IHX4dJJme3OrbnegTWwzNXO2aX31cIF1\WRiaIXtZY4hUnW{a3H0JINmdGy\|LDDJR\|UxKD1iMD6wO\|Eh\|ryPLh?=	MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{N{KwN{c,OTl2MkeyNFM9N2F-
Jurkat cells	MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			NWTzS4t3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBLSUt\|IHX4dJJme3OrbnegbJVu[W5icnXzeIlv\yCMdYLrZZQh[2WubIOsJGlEPTBiPTCwMlMyOSEQvF2u	MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{N{KwN{c,OTl2MkeyNFM9N2F-
HUE cells	MXvGeY5kfGmxbjDhd5NigQ>?		NEHUR206OCCvaX7z	NHzHepBKdmirYnn0bY9vKG:oIG\FS2ZTOiCrbjDIWWUh[2WubIOgZZN{\XO\|ZXSgZZMhcW6qaXLpeIlwdiCxZjDWSWdHNWmwZIXj[YQh[XW2b4Doc5NxcG:{eXzheIlwdiC2cnXheIVlKG[xcjC5NEBucW6\|IHLl[o9z\SCYRVfGJINp[WyuZX7n[UBjgSCHTFnTRUwhUUN3MDC9JFAvODdizszNMi=>	M3\HRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyMUewNVY{Lz5{MEG3NFE3OzxxYU6=
Sf9 cells	M3HrXGZ2dmO2aX;uJIF{e2G7		NIXZcGg3OCCvaX7z	MYHJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEeVVD3meZNm\CCQSVug[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkA3OCCvaX7zJIJ6KHKjZHnvcYV1emmlIIDyc5RmcW5ia3nuZZNmKGG\|c3H5MEBKSzVyIE2gNk4{KM7:TT6=	MlvLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB3OEC1OVIoRjJyNUiwOVUzRC:jPh?=
Sf21 cells	MlO5SpVv[3Srb36gZZN{[Xl?	MVKzNEB2VQ>?		NFfDbHZKdmirYnn0bY9vKG:oIHj1cYFvKEOKS{Kgb4lv[XOnIHX4dJJme3OnZDDpckBqdnOnY4SgV4YzOSClZXzsd{B2e2mwZzDwbI9{eGixLVPSSWJ1cWSnIHHzJJN2[nO2cnH0[UBifCB\|MDD1UUwhUUN3MDC9JFAvODJ5IN88UU4>	M4HrTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{O0O\|k3Lz5{MUOzOFc6PjxxYU6=
Sf21 cells	M4DadWZ2dmO2aX;uJIF{e2G7	NHHVVIg{OCC3TR?=		MmLWTY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCLS1utZYxxcGFiZYjwdoV{e2WmIHnuJIlve2WldDDT[lIyKGOnbHzzJJV{cW6pIIDoc5NxcG9vVXzp[4h1NUmtYYDwZWIu[WyyaHGgZZMhe3Wkc4TyZZRmKGG2IEOwJJVONCCLQ{WwJF0hOC5yM{mg{txONg>?	MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN\|NEe5Okc,OjF\|M{S3PVY9N2F-
Sf21 cells	M4\mN2Z2dmO2aX;uJIF{e2G7	NXzoOVR6OzBidV2=		MUXJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEmNSz3i[ZRiKGW6cILld5Nm\CCrbjDpcpNm[3RiU3[yNUBk\WyuczD1d4lv\yCyaH;zdIhwNVWuaXfoeE1Kc2GycHHCMYFteGijIHHzJJN2[nO2cnH0[UBifCB\|MDD1UUwhUUN3MDC9JFAvPDlizszNMi=>	MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN\|NEe5Okc,OjF\|M{S3PVY9N2F-
HeLa cells	M{G1bmN6fG:2b4jpZ4l1gSCjc4PhfS=>		MVO0PEBp	MX7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlAxODByNDFOwG0v	MnHMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF\|OEixPVEoRjJzM{i4NVkyRC:jPh?=
MCF7 cells	NGOxfWtEgXSxdH;4bYNqfHliYYPzZZk>		NULGSGVvPDhiaB?=	NEf6NGFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjB3IN88UU4>	MnW0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF\|OEixPVEoRjJzM{i4NVkyRC:jPh?=
HT-29 cells	NV3IcoRXTnWwY4Tpc44h[XO\|YYm=		Mn7TNkBp	MkTDSYZn\WO2IH;uJI1qfG:laH;u[JJq[WxibXXtZpJidmVicH;0[Y51cWGuIHnuJIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEKgbJJ{KHW\|aX7nJGpENTFic4ThbY5qdmdiYomg[ox2d3Knc3PlcoNmKGG\|c3H5MEBKSzVyIE2gNE4xODJizszNMi=>	MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR{OEO3OUc,OjF2MkizO\|U9N2F-
HeLa cells	NUfJfIpSS3m2b4TvfIlkcXS7IHHzd4F6		NV\pR4xrPDhiaB?=	NYC2[ZlxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMECwNFQh\|ryPLh?=	MorZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEi2OVUoRjJzNEi4OlU2RC:jPh?=
MCF7 cells	M3rZW2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MUW0PEBp	Mk\RR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xPSEQvF2u	NXr0RXMyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFg3PTVpPkKxOFg5PjV3PD;hQi=>
HT-29 cells	M{DkT2Z2dmO2aX;uJIF{e2G7			MWrJcohq[mm2aX;uJI9nKG2rdH;jbI9v\HKrYXygcYVu[nKjbnWgdI91\W62aXHsJIlvKGi3bXHuJGhVNTJ7IHPlcIx{KHW\|aX7nJGpEOSCmeXWgd5RicW6rbnegZpkh\my3b4Lld4NmdmOnIIDsZZRmKHKnYXTldkBie3OjeTygTWM2OCB;IECuNFAzPSEQvF2u	MlPKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVMoRjJzNUGzNlk{RC:jPh?=
SF268 cells	NG\sSphEgXSxdH;4bYNqfHliYYPzZZk>		M4jNZ\|Q5KGh?	NULSOHdnS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0Z{NkigZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDBwMES0JO69VS5?	MlPWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
CHOK1 cells	Ml;XR5l1d3SxeHnjbZR6KGG\|c3H5		M{TOS\|Q5KGh?	MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDTG9MOSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gNE4yOyEQvF2u	NIS2[2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
H460 cells	NYTrbYdGS3m2b4TvfIlkcXS7IHHzd4F6		NGWxOIE1QCCq	M2jKSGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGg1PjBiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFMvPiEQvF2u	NWDleW1[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTRpPkKxOVE{Ojl2PD;hQi=>
HT-29 cells	M3jVdGN6fG:2b4jpZ4l1gSCjc4PhfS=>		MoraOFghcA>?	MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gN{43KM7:TT6=	NHLC[mU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
MCF7 cells	M1;mR2N6fG:2b4jpZ4l1gSCjc4PhfS=>		Ml7zOFghcA>?	MlHxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gNVEh\|ryPLh?=	MmLqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
SW1116 cells	MXLGeY5kfGmxbjDhd5NigQ>?		MWmyOEBp	Mk\lTY5pcWKrdHnvckBw\iC2ZXzvcYVz[XOnIHnuJIh2dWGwIGPXNVEyPiClZXzsd{Bi\nSncjCyOEBpenNiYomgWHJCWC2SQ2KtSWxKW0FiYYPzZZktKEmFNUCgQUA5NjN{IN88UU4>	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl4MkWyN{c,OjF7NkK1NlM9N2F-
HT-29 cells	NVe5[2x{SXCxcITvd4l{KGG\|c3H5		NGewS5ozKGh?	Mn3WTY5lfWO2aX;uJI9nKGGyb4D0c5NqeyCrbjDoeY1idiCKVD2yPUBk\WyuczDhd5Nme3OnZDDy[YR2[3Srb36gc4YhdWm2b3Poc45lemmjbDDt[Y1jemGwZTDwc5RmdnSrYXygZYZ1\XJiMjDodpMh[nlidYPpcochUkNzIIP0ZYlvcW6pIHL5JIZtfW:{ZYPj[Y5k\SClZXzsMYJie2WmIHHzd4F6NCCHREWwJF0hOC5yMEK2JO69VS5?	MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl5M{GwNUc,OjF7N{OxNFE9N2F-
LoVo cells	NHrLWmpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		M4TWUlQ5KHSxIEeyJIg>	NG\rZoJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFzvWo8h[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMECxJO69VS5?	M1XLc\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI6Lz5{MkG4NlkzQTxxYU6=
ST486 cells	MXrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NHjRZYQ1QCC2bzC3NkBp	M3HOXWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2S0PFYh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEC3JO69VS5?	M2Dw[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI6Lz5{MkG4NlkzQTxxYU6=
DLD1 cells	MnjuRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		MWG0PEB1dyB5MjDo	NHPtVo5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTMSFEh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEC5JO69VS5?	NEHFVJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkG4NlkzQSd-MkKxPFI6Ojl:L3G+
B16F10 cells	NV\xVWQySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		NGTDXpQ1QCCq	NF3wdpVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFKxOmYyOCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNk45OiEQvF2u	M1rMRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUCzN\|Y1Lz5{MkWwN\|M3PDxxYU6=
MCF7 cells	MXrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		M2Lq[FQ5KGh?	NWP0WHRWSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCzMlA4KM7:TT6=	M2\l[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUCzN\|Y1Lz5{MkWwN\|M3PDxxYU6=
A431 cells	NYPqco81S3m2b4TvfIlkcXS7IHHzd4F6		MYOyOEBp	NXXoO4YxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTR\|MTDj[YxteyCjZoTldkAzPCCqcoOgeZNqdmdiQX7u[ZhqdiCYZV\JWGMweHKxcHnkbZVuKGmxZHnk[UB{fGGrbnnu[{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkC3JO69VS5?	M4Lv[\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUSxNFUyLz5{MkW0NVA2OTxxYU6=
MCF7 cells	NF;6PGFEgXSxdH;4bYNqfHliYYPzZZk>		M4rFNlI1KGh?	NFvNbW5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFI1KGi{czD1d4lv\yCDbn7lfIlvKF[nRlnUR{9xem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMUig{txONg>?	NFzKbVc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW0NVA2OSd-MkK1OFExPTF:L3G+
BJ cells	MkLCR5l1d3SxeHnjbZR6KGG\|c3H5		MkHqO\|IhcA>?	MVfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCTkBk\WyuczDh[pRmeiB5MjDodpMh[nliQ3HsZ4VqdiCDTTDhd5NigSxiSVO1NEA:KDBwMECyJO69VS5?	MlrOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7MkGwPFEoRjJ{OUKxNFgyRC:jPh?=
CEM cells	NUDobFg5S3m2b4TvfIlkcXS7IHHzd4F6		NYXmfIZQPzJiaB?=	MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPhcINmcW5iQV2gZZN{[XluIFnDOVAhRSByLkCyN{DPxE1w	NVjCd4l4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
MCF7 cells	MV;DfZRwfG:6aXPpeJkh[XO\|YYm=		NF7od4w4OiCq	MoXsR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgR4Ft[2WrbjDBUUBie3OjeTygTWM2OCB;IECuNFY1KM7:TT6=	MkjHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7MkGwPFEoRjJ{OUKxNFgyRC:jPh?=
HeLa cells	M1TZRmN6fG:2b4jpZ4l1gSCjc4PhfS=>		MWG3NkBp	Ml60R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgR4Ft[2WrbjDBUUBie3OjeTygTWM2OCB;IECuNVc2KM7:TT6=	MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl{MUC4NUc,OjJ7MkGwPFE9N2F-
HepG2 cells	NXjYRmJiTnWwY4Tpc44h[XO\|YYm=		NFLTe5AzPCCq	NXrRZZVyUW6qaXLpeIlwdiCxZjD0[YxwdWW{YYPlJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFI1KGi{czDifUBVWkGSLWDDVk1GVEmVQTDhd5NigSxiSVO1NEA:KDRwMUSg{txONg>?	MlP5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
SW1116 cells	NXrvbFlKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		NYnKd5gzPDhiaB?=	MoXMRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCVV{GxNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTC0Mlk2KM7:TT6=	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
HepG2 cells	M1nVVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NX7GU2FoPDhiaB?=	MV7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy\|IHHmeIVzKDR6IHjyd{BjgSCPVGSgcYV1cG:mLDDJR\|UxKD1iNj63N{DPxE1w	MmDSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
BGC823 cells	MmXvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		Mk\aOFghcA>?	NWr5NHFFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCvZYToc4QtKEmFNUCgQUA3Njh\|IN88UU4>	MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
HeLa cells	MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NVG0VVg2PDhiaB?=	NEPNVW9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTC5MlEzKM7:TT6=	M1uxW\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
HCT116 cells	MXTGeY5kfGmxbjDhd5NigQ>?			MUjJcohq[mm2aX;uJI9nKFSQSVutcYVlcWG2ZXSgWGNHPC:kZYThMYNie2WrbjD0doFve2O{aYD0bY9vKGmwIHj1cYFvKEiFVEGxOkBk\WyuczDifUBj\XSjLXzhZ5RidWG\|ZTDy[ZBwenSncjDn[Y5mKGG\|c3H5MEBKSzVyIE2gNE4xOzlizszNMi=>	M1;h[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MkOyNFYxLz5{M{KzNlA3ODxxYU6=
HepG2 cells	NED1c29HfW6ldHnvckBie3OjeR?=		MWC0PEBp	NH3xVHJKdmirYnn0bY9vKG:oIITlcI9u\XKjc3WgbY4hcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHRTSVBvUFPSMWVNUVODLDDJR\|UxKD1iOD6zJO69VS5?	M1HCRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|Mke5PFY1Lz5{M{K3PVg3PDxxYU6=
SW1116 cells	MWPGeY5kfGmxbjDhd5NigQ>?		M2\4b\|I1KGh?	NUjBO29JUW6qaXLpeIlwdiCxZjD0[YxwdWW{YYPlJIlvKGi3bXHuJHNYOTFzNjDj[YxteyCjZoTldkAzPCCqcoOgZpkhXFKDUD3QR3IuTUyLU1GgZZN{[XluIFnDOVAhRSB2LkG4JO69VS5?	MnXSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{OE[3OlEoRjJ2Mki2O\|YyRC:jPh?=
KE-97 cells	Mo\0R5l1d3SxeHnjbZR6KGG\|c3H5		MmTxO\|IhcA>?	NHm2U4xEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMTS17NzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2WubGTpeJJmNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMUOg{txONg>?	MlTmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|MkiyPFMoRjJ2M{K4Nlg{RC:jPh?=
Jurkat cells	NXzj[3BPS3m2b4TvfIlkcXS7IHHzd4F6		NYTFSmVYPzJiaB?=	MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDKeZJs[XRiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTy[U1IdG9ibIXtbY5me2OnboSgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjF2IN88UU4>	MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN{OEK4N{c,OjR\|MkiyPFM9N2F-
HuH7 cells	M3ntWWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NFPs[Hg4OiCq	NEHqR5JEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJfUh5IHPlcIx{KGGodHXyJFczKGi{czDifUBE\WyuVHn0doUuT2yxIHz1cYlv\XOlZX70JINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC5{MzFOwG0v	M2LsUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
BGC823 cells	NFXrTndEgXSxdH;4bYNqfHliYYPzZZk>		NUDY[IR4PzJiaB?=	Mlm1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmdEQDJ\|IHPlcIx{KGGodHXyJFczKGi{czDifUBE\WyuVHn0doUuT2yxIHz1cYlv\XOlZX70JINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC5\|ODFOwG0v	NGLud2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEOyPFI5Oyd-MkSzNlgzQDN:L3G+
MCF7 cells	Ml3lR5l1d3SxeHnjbZR6KGG\|c3H5		MlXjO\|IhcA>?	MnfKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgR4VtdFSrdILlMWdtdyCudX3pcoV{[2WwdDDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFAvPTJizszNMi=>	M3rYS\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
NIH/3T3 cells	MUDDfZRwfG:6aXPpeJkh[XO\|YYm=		Mo\ZPVYhcA>?	MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDOTWgwO1R\|IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	M4DkfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{[xOVIyLz5{NEO2NVUzOTxxYU6=
A2780 cells	MYPDfZRwfG:6aXPpeJkh[XO\|YYm=		M3nVPVk3KGh?	M{PremN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	NVvRb\|NJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOlE2OjFpPkK0N\|YyPTJzPD;hQi=>
HT-29 cells	NUPMd5JpS3m2b4TvfIlkcXS7IHHzd4F6		MUe5OkBp	NID3Z5REgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4>	MmrEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
8505C cells	NFqwdWFEgXSxdH;4bYNqfHliYYPzZZk>		MU[5OkBp	M4PtbmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJFg2ODWFIHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	NWHPWolFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOlE2OjFpPkK0N\|YyPTJzPD;hQi=>
518A2 cells	NYricZN7S3m2b4TvfIlkcXS7IHHzd4F6		NH2yd4c6PiCq	NE\CTlVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckA2OTiDMjDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4>	MkGxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
MCF7 cells	MVjDfZRwfG:6aXPpeJkh[XO\|YYm=		NFXz[IY6PiCq	MoPKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE41KM7:TT6=	NEm3dlQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
A549 cells	M1jTSGN6fG:2b4jpZ4l1gSCjc4PhfS=>		MlHKPVYhcA>?	MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTBiPTCwMlYh\|ryPLh?=	M2HHS\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{[xOVIyLz5{NEO2NVUzOTxxYU6=
V79 MZ cells	MmDxSpVv[3Srb36gZZN{[Xl?			NIrDOIlKdmirYnn0bY9vKG:oIHj1cYFvKGGuZH;zeIVzd26nIIP5cpRp[XOnIHX4dJJme3OnZDDpckBXPzliTWqgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCjbHTvd5Rmem:wZTDzfY51cGW\|aYOsJGlEPTBiPTCwMlAyOSEQvF2u	NFTOUZI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NESyNlUyQSd-MkS0NlI2OTl:L3G+
HEK293 cells	MnTOR5l1d3SxeHnjbZR6KGG\|c3H5		MYe3NkBp	NFjOUVVEgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPlcIxVcXSnclfsc{Bie3OjeTygTWM2OCB;IECuNFU3KM7:TT6=	MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd4M{K2Nkc,OjR5NkOyOlI9N2F-
HeLa cells	MonkRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		NH61cHczPCC2bzC0PEBp	MorGRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCKZVzhJINmdGy\|IHHmeIVzKDJ2IITvJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDJwN{Kg{txONg>?	MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd7MkixNUc,OjR5OUK4NVE9N2F-
A549 cells	M1HxcWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NWHyZ3lROjRidH:gOFghcA>?	M2T2UmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB{NDD0c{A1QCCqcoOgZpkhS0ONLUigZZN{[XluIFnDOVAhRSB\|LkC1JO69VS5?	NGm0Z3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe5NlgyOSd-MkS3PVI5OTF:L3G+
HepG2 cells	NWPITm9PS3m2b4TvfIlkcXS7IHHzd4F6			NHHOS2pEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyxiRVO1NEA:KDJizszNMi=>	MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTNzNkOxO{c,OjV\|MU[zNVc9N2F-
Raji cells	NID1bFZEgXSxdH;4bYNqfHliYYPzZZk>			NVG4eWc{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWmGsaTDj[YxteyxiRVO1NEA:KDJizszNMi=>	NWr4WGdWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNVY{OTdpPkK1N\|E3OzF5PD;hQi=>
BJ cells	M17jU2N6fG:2b4jpZ4l1gSCjc4PhfS=>			NXXGbJBnS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkpiY3XscJMtKEWFNUCgQUAzKM7:TT6=	MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTNzNkOxO{c,OjV\|MU[zNVc9N2F-
HEK293 cells	NULwUoMzS3m2b4TvfIlkcXS7IHHzd4F6			NFfjT2pEgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOsJGVEPTBiPTCyJO69VS5?	NET0eJU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUOxOlMyPyd-MkWzNVY{OTd:L3G+
A549 cells	NGLmZXVEgXSxdH;4bYNqfHliYYPzZZk>		NVXNNJBFPDhiaB?=	MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlAzKM7:TT6=	M{C1OlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK1PVM1Lz5{NUiyOVk{PDxxYU6=
HeLa cells	MX7DfZRwfG:6aXPpeJkh[XO\|YYm=		MVq0PEBp	MW\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlAzPSEQvF2u	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh{NUmzOEc,OjV6MkW5N\|Q9N2F-
PC3 cells	NVvTcFYzS3m2b4TvfIlkcXS7IHHzd4F6		NWrYcW9nPDhiaB?=	MWnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQR\|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuNFMyKM7:TT6=	NGLOTYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
MGC-803 cells	MWXGeY5kfGmxbjDhd5NigQ>?		MUWyOEBp	M1\keWlvcGmkaYTpc44hd2ZidHXsc41memG\|ZTDpckBpfW2jbjDNS2MuQDB\|IHPlcIx{KGGodHXyJFI1KGi{czDifUBVWkGSLWDDVk1GVEmVQTDhd5NigSxiSVO1NEA:KDhwOUeg{txONg>?	M1PWU\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUCwOlU3Lz5{NkmwNFY2PjxxYU6=
Sf9 insect cells	NFjFelZHfW6ldHnvckBie3OjeR?=		M2\I[FExKG2rboO=	NWL5[FJqUW6qaXLpeIlwdiCxZjDOMZRmem2rbnHsJGdUXCC2YXfn[YQhemWlb33ibY5idnRiZoXscE1t\W6pdHigbJVu[W5iQ1jLNUBmgHC{ZYPz[YQhcW5iYnHjeYxwfmm{dYOgV4Y6KGmwc3XjeEBk\WyuczDh[pRmeiBzMDDtbY5{KGK7IHz1cYlv\XOlZX70JGFFWC2JbH:gZZN{[XluIFnDOVAhRSByLkCwNVIh\|ryPLh?=	Mnf3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyOEmyNVEoRjJ5MEi5NlEyRC:jPh?=
Sf21 cells	MnTXSpVv[3Srb36gZZN{[Xl?		M2fjVVYxKG2rboO=	NISyPJRKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFrBT\|Ih\XiycnXzd4VlKGmwIGPmNlEh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIGXsbYdpfC2FQVfBS2FKTVSGS1XZXXRXU0RicHjvd5Bpd3K7bHH0bY9vKHC{ZT3pcoN2[mG2ZXSgZoVnd3KnIIP1ZpN1emG2ZTDh[IRqfGmxbjDhcoQhdWWjc4Xy[YQh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDk[ZRm[3Srb36gcYV1cG:mLDDJR\|UxKD1iMD6wNFIh\|ryPLh?=	M1:yblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUO3N\|U6Lz5{N{GzO\|M2QTxxYU6=
Neuro2a cells	NFHyOWREgXSxdH;4bYNqfHliYYPzZZk>		M4HtUlczKGh?	MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDO[ZVzdzKjIHPlcIx{KGG\|c3Xzd4VlKGG\|IHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjBzMUOg{txONg>?	M1fzelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUWyOFI4Lz5{OEG1NlQzPzxxYU6=
MDA-MB-231 cells	MYfGeY5kfGmxbjDhd5NigQ>?		NV\zcnhOOTZiaB?=	M4K4VGlvcGmkaYTpc44hd2ZicnX0bY5w[myjc4TvcYEheHKxdHXpckBxcG:\|cHjvdplt[XSrb36gbY4hcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiBzNjDodpMh[nliSH;lZ4h{fCB\|M{O0NkB{fGGrbnnu[{Bj[XOnZDDmcJVwemW\|Y3XuZ4Uh[XO\|YYmsJGlEPTBiPTCwMlA3PiEQvF2u	M2H3[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEOxN\|QzLz5{OESzNVM1OjxxYU6=
Sf9 insect cells	M3LKSmZ2dmO2aX;uJIF{e2G7		NY\WV446OjBibXnudy=>	M4PDb2lvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iTj30[ZJucW6jbHz5JGdUXC22YXfn[YQhTUeIUjDMPFU5Wi:WN{mwUU9EPzl5UzD0dolxdGVibYX0ZY51KGW6cILld5Nm\CCrbjDiZYN2dG:4aYL1d{BqdiCVZkmgbY5{\WO2IHPlcIx{KHC{ZXnuZ5Vj[XSnZDDmc5IhOjBibXnud{Bnd2yub4fl[EBjgSCjZHTpeIlwdiCxZjDbN\|NRZS2DVGCgcYVie3W{ZXSgZYZ1\XJiMjDodpMh[nliZnnseIVzNWKrbnTpcochdWW2aH;kMEBKSzVyIE2gNE4xODB{OTFOwG0v	NUDUTWxyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0PFIyPTFpPkK4OFgzOTVzPD;hQi=>
HEK293 cells	M4TZZ2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MYq3NkBp	NHnwRY1EgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOgZZN{\XO\|ZXSgZZMh\GWlcnXhd4UhcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTldkBIdG9ibIXtbY5me2OnboSgZZN{[XluIFPDOVAhRSByLkCwN\|U1KM7:TT6=	NH6xUZA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[yOFcxOSd-Mki2NlQ4ODF:L3G+
BT549 cells	NXLPWFVxS3m2b4TvfIlkcXS7IHHzd4F6		MlXQNlQhcA>?	MV3DfZRwfG:6aXOgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCEVEW0PUBk\WyuczDpcoN2[mG2ZXSg[o9zKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkC4JO69VS5?	NFLpR4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEewOVQ{Oid-Mki3NFU1OzJ:L3G+
MDA-MB-468 cells	M1XtPWN6fG:2b4jpZ4l1gSCjc4PhfS=>		MVyyOEBp	NED6ZYJEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvNE[4JINmdGy\|IHnuZ5Vj[XSnZDDmc5IhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMUWg{txONg>?	MmfGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5MEW0N\|IoRjJ6N{C1OFMzRC:jPh?=
MDA-MB-231 cells	M3f3R2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MkDKNlQhcA>?	MUTDfZRwfG:6aXOgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCPRFGtUWIuOjNzIHPlcIx{KGmwY4XiZZRm\CCob4KgNlQhcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvOjRizszNMi=>	NXfPdGVsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NFU1OzJpPkK4O\|A2PDN{PD;hQi=>
Vero cells	NIPkWZdEgXSxdH;4bYNqfHliYYPzZZk>		M3zUZlIh\GG7cx?=	M{TadGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEGocnnjZY4h\3KnZX6gcY9vc2W7IG\ldo8h[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFIh\GG7czDifUBk\WyuLYTpeIVzNWeubzDseY1qdmW\|Y3XueEBie3OjeTygWGM2OCB;IECuNFAzPCEQvF2u	M{O0PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{[zOlQ2Lz5{OEe2N\|Y1PTxxYU6=
L929 cells	NHjjfJJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		NWnae3R1PSCmYYnz	M3PP[GFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEmyPUBk\WyuczDh[pRmeiB3IHThfZMh[nliV2PUMVEh[XO\|YYmsJGlEPTBiPTCwMlIh\|ryPLh?=	M1\ZUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUW2PVE2Lz5{OEm1OlkyPTxxYU6=
KB-3-1 cells	NEXoS4lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MX21JIRigXN?	NFTmSXJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFvCMVMuOSClZXzsd{Bi\nSncjC1JIRigXNiYomgW3NVNTFiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	NUjCb5BJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5OVY6OTVpPkK4PVU3QTF3PD;hQi=>
MCF7 cells	MoLmRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		MoPTOUBl[Xm\|	MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPSCmYYnzJIJ6KFeVVD2xJIF{e2G7LDDJR\|UxKD1iMT64JO69VS5?	MnvEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh7NU[5NVUoRjJ6OUW2PVE2RC:jPh?=
FS4-LTM cells	NGrOUXFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MXSyOEBp	Mn;JRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCIU{StUHROKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDXV3QuOSCjc4PhfUwhUUN3MDC9JFIvQCEQvF2u	NE\ofYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm1OlkyPSd-Mki5OVY6OTV:L3G+
Vero cells	NF;lWnhEgXSxdH;4bYNqfHliYYPzZZk>		NVfTXGRiOiCmYYnz	Mn;TR5l1d3SxeHnjbZR6KGGpYXnud5QhSW[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDh[pRmeiB{IHThfZMh[nliQ3XscHRqfGW{LVfsc{BtfW2rbnXzZ4VvfCClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuNFAzPCEQvF2u	M3X1ZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUmzNVA3Lz5{OEm5N\|ExPjxxYU6=
HepG2 cells	Mm\hR5l1d3SxeHnjbZR6KGG\|c3H5	MlfYNVAxKHWP	MYezJIRigXN?	M{\Hc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG2IEGwNEB2VSCjZoTldkA{KGSjeYOgZpkhS2WubGTpeIVzNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMEG4JO69VS5?	NW\xVXh{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5PVMyODZpPkK4PVk{OTB4PD;hQi=>
NIH/3T3 cells	MVnDfZRwfG:6aXPpeJkh[XO\|YYm=		NH3pN5o6PiCq	MWTDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDOTWgwO1R\|IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEWFNUCgQUAxNjByODFOwG0v	NVfoZpVpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxPVc4OzBpPkK5NVk4PzNyPD;hQi=>
518A2 cells	MWLDfZRwfG:6aXPpeJkh[XO\|YYm=		MoTrPVYhcA>?	NWS5OFh1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hPTF6QUKgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiRVO1NEA:KDBwMEOg{txONg>?	NF76SYY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUG5O\|c{OCd-MkmxPVc4OzB:L3G+
A549 cells	MmTaR5l1d3SxeHnjbZR6KGG\|c3H5		NF:3Xmg6PiCq	M1HZUWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhTUN3MDC9JFAvODRizszNMi=>	NHTvUWs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUG5O\|c{OCd-MkmxPVc4OzB:L3G+
MCF7 cells	NW\3THF2S3m2b4TvfIlkcXS7IHHzd4F6		NULwcXZMQTZiaB?=	M3y5UWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhTUN3MDC9JFAvOSEQvF2u	M2Tq[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
A2780 cells	M2TDdWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NFvMT3k6PiCq	NYXVSGVQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiRVO1NEA:KDBwMUKg{txONg>?	M{Ds[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
HT-29 cells	M4DvT2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MkHzPVYhcA>?	NITuTHpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5zNTFOwG0v	NX3q[4M3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxPVc4OzBpPkK5NVk4PzNyPD;hQi=>
PC3 cells	Mnf4R5l1d3SxeHnjbZR6KGG\|c3H5			NX3FVm1MS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN\|IHPlcIx{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEmFNUCgQUAxNjBzNzFOwG0v	M3H6bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7M{i5NVIzLz5{OUO4PVEzOjxxYU6=
HCT116 cells	MlPOR5l1d3SxeHnjbZR6KGG\|c3H5			NE\zfW1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiSVO1NEA:KDBwMEW1JO69VS5?	NYLoVoZNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmzPFkyOjJpPkK5N\|g6OTJ{PD;hQi=>
insect cells	NE[0PJZHfW6ldHnvckBie3OjeR?=		Mof3N\|AhdWmwcx?=	M4nKS2lvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iUFTHSnJj\XSjIHX4dJJme3OnZDDpckBqdnOnY4SgZ4VtdHNidYPpcochXWyrZ3j0MXBwdHliR1HUX2VCYShzOkG6NUlediCjczDzeYJ{fHKjdHWgZYZ1\XJiM{CgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjByMEe2JO69VS5?	NHzVTVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
Sf9 insect cells	MVjGeY5kfGmxbjDhd5NigQ>?		MofDOlAhdWmwcx?=	MWjJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEuGUjDlfJBz\XO\|ZXSgbY4hW2Z7IHnud4VkfCClZXzsd{B2e2mwZzDVcIlocHRvQ1HHRWdCUUWWRFvFXXlVXkuGIHHzJJN2[nO2cnH0[UBi\nSncjC2NEBucW6\|IHL5JGxCVkOHIH3leIhw\CxiSVO1NEA:KDBwMECyNUDPxE1w	MoDYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
insect cells	M2SydGZ2dmO2aX;uJIF{e2G7		M162eFExKG2rboO=	NYXoTodFUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDTdoMh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{B2e2mwZzDVcIlocHRvUH;sfUBISVSdRVHZLFE7OTpzKW3uJIF{KHO3YoP0doF1\SCjZoTldkAyOCCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFA2KM7:TT6=	M{fmOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	MmSxSpVv[3Srb36gZZN{[Xl?		MVSxOUBucW6\|	M{PycGlvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iQ1TLNU9EgWOuaX6gRkBmgHC{ZYPz[YQhcW5iaX7z[YN1KGOnbHzzJJV{cW6pIGXsbYdpfC2FRl\LUmlXXFCUVGDQVHNST0tvYX3p[IUh[XNic4Xid5Rz[XSnIHHmeIVzKDF3IH3pcpMh[nliTFHOR2UhdWW2aH;kMEBKSzVyIE2gNE4xOjVizszNMi=>	MknJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
insect cells	NEnXV2hHfW6ldHnvckBie3OjeR?=		Mnq0NVUhdWmwcx?=	MWHJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEOGS{GvR5lkdGmwIFKg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuS0[IS17JWnRRWlSSUGDTVWdMNWGvaXTlJIF{KHO3YoP0doF1\SCjZoTldkAyPSCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFI2KM7:TT6=	NILySVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
Sf9 insect cells	MUPGeY5kfGmxbjDhd5NigQ>?		NFXw[ZYyPSCvaX7z	NIDoU3pKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIF\seFEh\XiycnXzd4VlKGmwIGPmPUBqdnOnY4SgZ4VtdHNidYPpcochXWyrZ3j0MXRMKHCncITp[IUh[XNic4Xid5Rz[XSnIHHmeIVzKDF3IH3pcpMh[nliTFHOR2UhdWW2aH;kMEBKSzVyIE2gNE4xOzVizszNMi=>	NXnRNWtoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
Sf21 insect cells	M{TUR2Z2dmO2aX;uJIF{e2G7		MojCNVUhdWmwcx?=	MnWxTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCDdYLvdoEuSSCneIDy[ZN{\WRiaX6gV4YzOSCrboPlZ5Qh[2WubIOgeZNqdmdiVXzp[4h1NVKUUmPMUGUh[XNic4Xid5Rz[XSnIHHmeIVzKDF3IH3pcpMh[nliTFHOR2UhdWW2aH;kMEBKSzVyIE2gNE4xOzlizszNMi=>	Mn7yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
insect cells	MmXISpVv[3Srb36gZZN{[Xl?		NVKyNGZ3PjBibXnudy=>	MVnJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEGNVEGg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCFUlXCeIll\SCjczDzeYJ{fHKjdHWgZYZ1\XJiNkCgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjB3NjFOwG0v	NH70O3o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
Sf9 insect cells	MVHGeY5kfGmxbjDhd5NigQ>?		M3rGSFYxKG2rboO=	NIrHV5FKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIF\BT{BmgHC{ZYPz[YQhcW5iU3[5JIlve2WldDDj[YxteyC3c3nu[{BWdGmpaIStWGsheGWydHnk[UBieyC\|dXLzeJJifGViYX\0[ZIhPjBibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlA3OiEQvF2u	MnvMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
insect cells	NF;lNI5HfW6ldHnvckBie3OjeR?=		MXW2NEBucW6\|	NIH1[JBKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIFHCUEBmgHC{ZYPz[YQhcW5iaX7z[YN1KGOnbHzzJJV{cW6pIGXsbYdpfC2WSzDw[ZB1cWSnIHHzJJN2[nO2cnH0[UBi\nSncjC2NEBucW6\|IHL5JGxCVkOHIH3leIhw\CxiSVO1NEA:KDBwMkmg{txONg>?	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
insect cells	NGjlTGlHfW6ldHnvckBie3OjeR?=		NHjrbYo3OCCvaX7z	NWHTUIpyUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDjMW1GXCCneIDy[ZN{\WRiaX6gbY5{\WO2IHPlcIx{KHW\|aX7nJHVtcWeqdD3DRWdCT0GLRWTET2V[YVSYS1SgZZMhe3Wkc4TyZZRmKGGodHXyJFYxKG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6zNUDPxE1w	MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
PC3 cells	MYHDfZRwfG:6aXPpeJkh[XO\|YYm=		NXO4R4RQPzJiaB?=	NWWzcWtqS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN\|IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjB\|OTFOwG0v	M3u1e\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUW4NVE6Lz5{OUW1PFEyQTxxYU6=
Sf9 cells	MmnvSpVv[3Srb36gZZN{[Xl?		NYXSepYxPDVibXnudy=>	NVjnfG9XUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDDMZRmem2rbnHsJGhqey22YXfn[YQwVi22ZYLtbY5idCCJU2SteIFo\2WmIFXHSnIhMDZ4ODD0c{AyOjFyIILld4llfWW\|KTDlfJBz\XO\|ZXSgbY4h[mGldXzveolzfXNiaX7m[YN1\WRiU3[5JINmdGy\|IIXzbY5oKFCxbImtLGdtfSxiVInyLUBieyC\|dXLzeJJifGVibXXhd5Vz\WRiYX\0[ZIhPDVibXnueZRmeyCkeTDLbY5ie2VvR3zvJIx2dWmwZYPj[Y51KGG\|c3H5MEBKSzVyIE2gNE4xPDdizszNMi=>	Mkj1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl7MEK3NVkoRjJ7OUCyO\|E6RC:jPh?=
Sf9 cells	MXTGeY5kfGmxbjDhd5NigQ>?		M1v5UVQ2KG2rboO=	MUDJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKE5vdHXycYlv[WxiR2PUMZRi\2enZDDISXIzKCh4N{mgeI8hOTJ3NTDy[ZNq\HWnczmg[ZhxemW\|c3XkJIlvKGKjY4Xsc5ZqenW\|IHnu[oVkfGWmIGPmPUBk\WyuczD1d4lv\yCSb3z5MUhIdHVuIGT5dkkh[XNic4Xid5Rz[XSnIH3lZZN2emWmIHHmeIVzKDR3IH3pcpV1\XNiYomgT4lv[XOnLVfsc{BtfW2rbnXzZ4VvfCCjc4PhfUwhUUN3MDC9JFAvODZyODFOwG0v	M4n1c\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7OUCyO\|E6Lz5{OUmwNlcyQTxxYU6=
HT-29 cells	M4PaVGZ2dmO2aX;uJIF{e2G7		MYGzJIg>	MmfMTY5pcWKrdHnvckBw\iCvaYTvZ4hwdmS{aXHsJI1mdWK{YX7lJJBwfGWwdHnhcEBqdiCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA{KGi{czDifUBLSy1zIIP0ZYlvcW6pIHLhd4VlKG[udX;y[ZNk\W6lZTDhd5NigSxiSVO1NEA:KDBwMEKg{txONg>?	Mmq1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByNUexOVUoRjNyMEW3NVU2RC:jPh?=
Sf9 cells	MlmxSpVv[3Srb36gZZN{[Xl?			NXviNY9uUW6qaXLpeIlwdiCxZjDOMZRmem2rbnHsJGZNSUdvdHHn[4VlKGi3bXHuJIZ2dGxvbHXu[5RpKEOGS{GyJEgyKHSxIEG0PVAhemW\|aXT1[ZMqN05vdHXycYlv[WxiSHnzMZRi\2enZDDDfYNMKChzIITvJFU5OCC{ZYPp[JVmeyliZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gRXRRNWSncHXu[IVvfCCXTHnnbJQuPEVvQmCxJEhVcHJ\|Nz;UbJI1Pilic4Xid5Rz[XSnIIDldJRq\GVicHjvd5Bpd3K7bHH0bY9vKHC{LDDJR\|UxKD1iMD6wOVMh\|ryPLh?=	Mnu0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByNkezOVgoRjNyME[3N\|U5RC:jPh?=
Sf9 cells	NGfvSnVHfW6ldHnvckBie3OjeR?=			NELYfW9KdmirYnn0bY9vKG:oIF6teIVzdWmwYXygSmxCTy22YXfn[YQhcHWvYX6g[pVtdC2uZX7neIghS0SNMUKgLFEhfG9iMUS5NEBz\XOrZIXld{kwVi22ZYLtbY5idCCKaYOteIFo\2WmIFP5Z2shMDFidH:gOVgxKHKnc3nkeYV{MSCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIF{e2W\|c3XkJIF{KHKnZIXjeIlwdiCrbjDBWHAu\GWyZX7k[Y51KFWOaXfoeE01TS2EUEGgLHRpejN5L2TodlQ3MSC\|dXLzeJJifGVicHXweIll\SCyaH;zdIhwenmuYYTpc44heHJuIFnDOVAhRSByLkC1N{DPxE1w	MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB4N{O1PEc,OzByNkezOVg9N2F-
Sf9 cells	NXTZO4xtTnWwY4Tpc44h[XO\|YYm=			M{LqT2lvcGmkaYTpc44hd2ZiTj30[ZJucW6jbDDGUGFINXSjZ3fl[EBpfW2jbjDmeYxtNWynbnf0bEBETEtzMzCoNUB1dyBzNUGyJJJme2mmdXXzLU9PNXSncn3pcoFtKEircz30ZYdo\WRiQ4njT{ApOSC2bzC1PFAhemW\|aXT1[ZMqKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIFHUVE1l\XCnbnTlcpQhXUyrZ3j0MVRGNUKSMTCoWIhzOzdxVHjyOFYqKHO3YoP0doF1\SCyZYD0bYRmKHCqb4PwbI9zgWyjdHnvckBxeixiSVO1NEA:KDBwMEW3JO69VS5?	NVW0OVltRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CwOlc{PThpPkOwNFY4OzV6PD;hQi=>
Sf9 cells	MYTGeY5kfGmxbjDhd5NigQ>?			NYLDTnY1UW6qaXLpeIlwdiCxZjDOMZRmem2rbnHsJGZNSUdvdHHn[4VlKGi3bXHuJIZ2dGxvbHXu[5RpKEOGS{GzJEgyKHSxIEG1NVIhemW\|aXT1[ZMqN05vdHXycYlv[WxiSHnzMZRi\2enZDDDfYNMKChzIITvJFU5OCC{ZYPp[JVmeyliZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gRXRRNWSncHXu[IVvfCCXTHnnbJQuPEVvQmCxJEhVcHJ\|Nz;UbJI1Pilic4Xid5Rz[XSnIIDldJRq\GVicHjvd5Bpd3K7bHH0bY9vKHC{LDDJR\|UxKD1iMD6wOVch\|ryPLh?=	NEfTemc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEC2O\|M2QCd-M{CwOlc{PTh:L3G+
HCT116 cells	M4H0XWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NHPXVlE1QCCq	NGG2RWhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuNFMh\|ryPLh?=	MkjDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=
Huh7.5 cells	NWfpb3FFS3m2b4TvfIlkcXS7IHHzd4F6		MUO0PEBp	MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIeYg4NjViY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwNjFOwG0v	MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODFyNkK5NUc,OzBzME[yPVE9N2F-
K562 cells	MmDVR5l1d3SxeHnjbZR6KGG\|c3H5		M2n1T\|Q5KGh?	MkDpR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT\|U3OiClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS55IN88UU4>	MmGwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=
LO2 cells	M4ftPWN6fG:2b4jpZ4l1gSCjc4PhfS=>		M3rOSlQ5KGh?	MorIR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUG8zKGOnbHzzJIF{e2W\|c3XkJIF{KGSnY4LlZZNmKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA6NjVizszNMi=>	M1Tlc\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUC2NlkyLz5\|MEGwOlI6OTxxYU6=

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	FAK / RIP; PubMed: 15121855 Mol Cell Biol Western blot (WB) analysis of BT-20 and BT-474 lysates treated with staurosporine (200 nM). Control cells were treated with dimethyl sulfoxide for 18 h. p-Akt / Akt / PARP /Cleaved PARP; PubMed: 24174874 Int J Nanomedicine Western blot analysis for Akt, P-Akt, and cleaved poly(ADP-ribose) polymerase. U87 cells were incubated with 200 nM, 10 nM, and 0.1 nM of staurosporine encapsulated in liposomes and staurosporine for 32 hours. Ambra1; PubMed: 24587252 PLoS One SW620 cells treated with various doses of staurosporine for 6 h. Ambra1 levels were measured by Western blot.	15121855 24174874 24587252
Growth inhibition assay	Cell viability; PubMed: 25215174 Oxid Med Cell Longev Staurosporine reduces cerebellar astrocytes viability. (a) Cerebellar astrocytes were treated with staurosporine 0.1 μM, 0.25 μM, and 0.5 μM for 24 h and the cell viability was measured by MTT transformation. (b) Cerebellar astrocytes were treated with staurosporine 0.5 μM for 6, 12, and 24 h and the cell viability was measured by MTT transformation. Data are presented as mean ± SEM of four independent experiments. ∗ is significantly different from control (P < 0.05).	25215174
Immunofluorescence	Phalloidin / Type II collagen; PubMed: 22684244 Exp Mol Med Cell were cultured in the absence (a-f) or presence of staurosporine (STSN, 5 × 10-9M) or cytochalasin D (CD, 1 µg/ml) for 1 (upper panel) or 2 (lower panel) days at low density and stained for F-actin (Phalloidin) and type II collagen (Type II). STSN: Staurosporine. Tubulin / Actin; PubMed: 25215174 Oxid Med Cell Longev Morphological changes of astrocytes induced by St are evidenced by the rearrangement of cytoskeletal proteins. Astrocytes were treated with St (0.5 μM) for 12 hours and then were labelled with rhodamine-phalloidin or immunostained for tubulin. Representative images of phase contrast, rhodamine-phalloidin, and tubulin are shown in control and St treated astrocytes. Scale bar represents 50 μm. FAK 4.47; PubMed: 15121855 Mol Cell Biol BT-20 or BT-474 cell culture were plated on six-well plates and were treated with staurosporine (200 nM) after 24 h. After 6 h of treatment, cells were immunostained with anti-FAK 4.47 antibody (white arrowheads mark some focal adhesions). cleaved-caspase 3; PubMed: 19840952 Cardiovasc Res Representative images (×1000 magnification) showing vehicle treated (C) and staurosporine treated (D) cells stained with anti-cleaved caspase 3 antibody and DAPI. Annexin; PubMed: 15140398 Neoplasia Induction of apoptosis with staurosporine resulting in activation of the ICE-NIRF probe. Gli36 cells were treated with 50 µM staurosporine for 24 hours (A-C) or with the same percentage of DMSO (0.01%) to which experimental wells were exposed (D-488nm laser, E-633nm laser and F-bright field). To examine the role of caspase-1 in staurosporine-induced apoptosis and probe activation, cells were coincubated in caspase-1 inhibitor (10 µM) and staurosporine (G-I). Staurosporine induces apoptosis, indicated by the positive annexin staining viewed with the 488-nm laser (A), which colocalized with activated probe viewed with the 633-nm laser (B). Coincubation of the caspase-1 inhibitor with staurosporine did not completely block apoptosis, indicated by the relatively higher number of apoptotic cells stained with annexin (G), as those that activated the probe (H). Magnification, x 40; scale bar, 50 µM. Pyk2; PubMed: 19880522 J Biol Chem Pyk2 translocates to the nucleus upon staurosporine addition to ID8 cells. Confocal immunofluorescent analysis of endogenous Pyk2 upon DMSO (control) or 1 μm staurosporine addition for 2 h. The scale bar is 10 μm.	22684244 25215174 15121855 19840952 15140398 19880522

In vivo

In the gerbil and rat ischemia models, Staurosporine pretreatment (0.1-10 ng) before ischemia prevents neuronal damage in a dose-dependent manner, suggesting the involvement of PKC in CAl pyramidal cell death after ischemia. ^[8]

Protocol

Kinase Assay: ^[1]	- Collapse Enzyme assay and binding assay: Protein kinase C is assayed in a reaction mixture (0.25 mL) containing 5 μmol of Tris/HCl, pH 7.5, 2.5 μmol of magnesium acetate, 50 μg of histone II S, 20 μg of phosphatidylserine, 0.88 μg of diolein, 125 nmol of CaCl₂, 1.25 nmol of [γ-³²]ATP (5-10 × 10⁴ cpm/nmol) and 5 μg of partially purified enzyme. The binding of [³H]PDBu to protein kinase C is determined: Reaction mixture (200 μL contained 4 μmo1 of Tris/malate, pH 6.8, 20 μmol of KCl, 30 nmol of CaC1₂, 20 μg of phosphatidylserine, 5 μg of partially purified protein kinase C, 0.5% (final concentration) of DMSO,10 pmol of [³H]PDBu (l-3 × 10⁴ cpm/pmol) and 10 μL of various amounts of Staurosporine.
Cell Research: ^[3]	- Collapse Cell lines: PC12 Concentrations: Dissolved in DMSO, final concentration 1 μM Incubation Time: ~32 hours Method: Cells are exposed to Staurosporine for ~32 hours. Cells are fixed in 4% paraformaldehyde and stained with the DNA-binding dye Hoechst 33342. Cells are visualized under epifluorescence illumination, and the percentage of apoptotic cells (cells with condensed and fragmented DNA) is determined. (Only for Reference)
Animal Research: ^[8]	- Collapse Animal Models: Male Mongolian gerbils or male Wistar rats subjected to transient ischemia Dosages: ~10 ng Administration: Stereotaxically administered into the bilateral CAl subfield of the hippocampus (Only for Reference)

References

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Solubility (25°C)

In vitro	DMSO	4 mg/mL (8.57 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Staurosporine (AM-2282) SDF

Molecular Weight	466.53
Formula	C₂₈H₂₆N₄O₃
CAS No.	62996-74-1
Storage	3 years-20°C powder 2 years-80°C in solvent
Synonyms	Antibiotic AM-2282, STS
Smiles	CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

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Staurosporine (AM-2282)