Etoposide (VP-16)

Catalog No.S1225 Synonyms: VP-16213

For research use only.

Etoposide (VP-16, VP-16213) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.

Etoposide (VP-16) Chemical Structure

CAS No. 33419-42-0

Selleck's Etoposide (VP-16) has been cited by 220 publications

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Etoposide (VP-16, VP-16213) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.
Targets
Topo II [2]
(Cell-free assay)
In vitro

Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, which induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. [1] Etoposide inhibits the growth of murine angiosarcoma cell line (ISOS-1) in a 5 days-period with IC50 of 0.25 μg/mL. Cell growth of normal murine microvascular endothelial cells (mECs) is less sensitive to Etoposide with IC50 of 10 μg/mL). [2] Etoposide treated for 6 hr inhibits colonies of tetraploid variant of the human leukemic lymphoblast line CCRF-CEM with IC50 of 0.6 μM. [3] Etoposide treated for 2 hr inhibits growth of human pancreatic cancer cell line Y1, Y3, Y5, Y19, YM. YS, and YT with IC50s of 300 μg/mL, 300 μg/mL, 300 μg/mL, 91 μg/mL, 0.68 μg/mL, 300 μg/mL, 300 μg/mL, and 260 μg/mL, respectively. [4] Etoposide exposed for 1 hr inhibits growth of human glioma cell lines CL5, G142, G152, G111, and G5 with IC50 of 8, 9, 9.8, 10, and 15.8 μg/mL respectively for 12 days. Under same condition, the IC90 value is attained in cell lines CL5, G152, G142, and G111 at 26, 27, 32, and 33 μg/mL. Etoposide inhibition of topoisomerase II is homogeneous for each cell. The average inhibition rates are 15%, 21.8%, 31.8%, 41.5%, and 49.5% for 1, 2, 4, 8, and 16 μg Etoposide, respectively. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Kelly M3TufGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1y1VmlEPTB;MD6xNwKBkcLz4pEJNE4xOSEQvF2= NH\uWmk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm2NFI5Oid-MkW5OlAzQDJ:L3G+
KellyCis83 M3TnW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTBwMUdihKnDueLCiUCuNFIh|ryP MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTl4MEK4Nkc,OjV7NkCyPFI9N2F-
SK-N-AS MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLkVFFHUUN3ME2wMlI16oDLwsJihKkxNjB|IN88US=> M2LhNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OU[wNlgzLz5{NUm2NFI5OjxxYU6=
SK-N-ASCis24 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnPR2xKSzVyPUCuOVfjiIoEsfMAjVAvOTFizszN NHjtW2M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm2NFI5Oid-MkW5OlAzQDJ:L3G+
U87 M3XRdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M361WlAuPTBizszN NHO3UXk1QCCq M3zLUYRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTD3bIlkcCClYX6gZoUh\W6qYX7j[YQh[nlic3nsbYJqdmmw MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTd3MEK3N{c,OjV5NUCyO|M9N2F-
HCT116 NWrueo1MT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrQd3NmOC53LUKuOUDPxE1? NXLOVHpJPDkEoHlCpC=> NWK4PGVyUUN3ME2xMlc{yqEEsdMgNE4zOcLizszN NGO2U5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUe0Olc3Oyd-MkW3OFY4PjN:L3G+
HT-29 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\lZ4RtOC53LUKuOUDPxE1? NWGzVYllPDkEoHlCpC=> NYXxeWxoUUN3ME23MlLDqMLzwrCxMlA1yqEQvF2= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTd2Nke2N{c,OjV5NE[3OlM9N2F-
Caco2 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUewMlUuOi53IN88US=> M{X4PVQ5yqCqwrC= MkH1TWM2OD15LkK2xsDDucLiMT62POKh|ryP NHXp[WE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUe0Olc3Oyd-MkW3OFY4PjN:L3G+
COLO 205 MoXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4C3eVAvPS1{LkWg{txO MXi0POKhcMLi M3zmZmlEPTB;MT62NeKhyrIEoECuNFLDqM7:TR?= M4\1O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3N{S2O|Y{Lz5{NUe0Olc3OzxxYU6=
SW480 Mn62S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXiwMlUuOi53IN88US=> MXS0POKhcMLi NWmwPWtiUUN3ME20MlkzyqEEsdMgNE4{O8LizszN NYHUNpM4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3OFY4PjNpPkK1O|Q3PzZ|PD;hQi=>
HEK293T MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHJNU02KM7:TR?= MUW0POKhcMLi MlzUTWM2OD1{LkSyxsDDucLiMD6wOeKh|ryP M1PhS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3N{S2O|Y{Lz5{NUe0Olc3OzxxYU6=
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HEK293 M3OweGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVrmZWpnUUN3ME23MlE1yqEEsdMgNE4{PsLizszN NV7UdVZXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2NFMyOjJpPkK1OlA{OTJ{PD;hQi=>
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HCT15 MmHkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjhVmJyUUN3ME2wMlgyyqEEsdMgNE4xOcLizszN NYTrVoZkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2NFMyOjJpPkK1OlA{OTJ{PD;hQi=>
T47D M4Lab2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTNwMUlCpOKyyqByLkGxxsDPxE1? NIfabng9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[wN|EzOid-MkW2NFMyOjJ:L3G+
SMMC-7721 M4m4d2Z2dmO2aX;uJGF{e2G7 MmqxOFAh|ryP NUn0RYdXPDhiaB?= MonwSG1UVw>? NGXIW|hqdmS3Y3XzJO6{UDKDWDDmc4NqKG[xcn3heIlwdg>? M2m1bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NUS0N|YyLz5{NUW0OFM3OTxxYU6=
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Jurkat MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXO3NuKhcA>? NYrCTGFIUUN3ME2xMlLDqMLzwrCxMlXDqM7:TR?= NIT5O5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS4OlIyQSd-MkW0PFYzOTl:L3G+
HeLa NWHhR2RrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHTQSY04OsLiaB?= NH\hfVNKSzVyPUOuPeKhyrIEoEKuN:Kh|ryP NEm4dGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS4OlIyQSd-MkW0PFYzOTl:L3G+
MCF7  Mn\KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3ke2E2NTFyMDFOwG0> M{Tn[|ch\A>? M4\XeYlvcGmkaYTzJINmdGxiZ4Lve5RpKGmwIHGg[I9{\S2mZYDlcoRmdnRibXHucoVz M{XKXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NEeyOlE6Lz5{NUS3NlYyQTxxYU6=
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SH-EP  MmDNSpVv[3Srb36gRZN{[Xl? MWWyNOKh|rypL33s NEHNc2gzPMLiaB?= Mm\ObY5kemWjc3XzJJRp\SCneIDy[ZN{cW:wIH;mJIVv\G:pZX7veZMhTEWSUB?= NYLDVHFDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyOlE6QDFpPkK1NlYyQThzPD;hQi=>
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CAL27 NX;aRpl6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;zdlI1yqCq NIHncFdKSzVyPUWyMlHDqMLzwrCxMlA6yqEQvF2= Ml:xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MkC3NlkoRjJ3MkKwO|I6RC:jPh?=
FaDu NXXNOXBzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn:zNlTDqGh? MY\JR|UxRTJ3Lki5xsDDucLiMT6xN:Kh|ryP MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTJ{MEeyPUc,OjV{MkC3Nlk9N2F-
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MCF7 EV NYLU[ZAyTnWwY4Tpc44hSXO|YYm= MUOxNE0yODBizszN NIf1U48z6oDLaB?= NWnmVWp1TVSRUDDpcoR2[2W|IFHUUUBi[3SrdnH0bY9v NX7B[oJERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwPFgzODNpPkK1NFg5OjB|PD;hQi=>
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HT1080 NFjHRoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTJZmVbOS1zMECg{txO Mn7SOE8zPC92ODDo M{PGNmROW00EoB?= NVnpc3JFcW6mdXPld{Bk\WyuIHTlZZRpKHOrZ37p[olk[W62bImgbY4h[SC4ZYL5JIxwfyClb37j[Y51emG2aX;u M4TVclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEe4NFY1Lz5{NUC3PFA3PDxxYU6=
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RPMI-8226 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkjVOFghcA>? Mof3TWM2OD17MT6xxsDPxE1? MnTDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEiyN|YoRjJ3MES4NlM3RC:jPh?=
RPMI-8226 NGe2NXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2mzdFczKGh? MlPDTWM2OD1zND65xsDPxE1? MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB2OEKzOkc,OjVyNEiyN|Y9N2F-
U-266 NI[3blJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MliyNlQhcA>? NUTEbIFrUUN3ME24Ok4zyqEQvF2= MnPxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEiyN|YoRjJ3MES4NlM3RC:jPh?=
U-266 NIXhb5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVL0c49zPDhiaB?= NWH5RnRDUUN3ME22PE41yqEQvF2= M{H1TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES4NlM3Lz5{NUC0PFI{PjxxYU6=
U-266 MlL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLrO|IhcA>? NFj3dVdKSzVyPUK3MlTDqM7:TR?= M2rJT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES4NlM3Lz5{NUC0PFI{PjxxYU6=
Kelly MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLqNYduOC1zMDFOwG0> NGOxdHE4OsLiaB?= M3T6PWlEPTB;MT61NVjDqM7:TR?= M4\seFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEC4PVAxLz5{NUCwPFkxODxxYU6=
SH-SY5Y  MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PQOFAuOTBizszN MYC3NuKhcA>? Mn3mTWM2OD1yLke1OOKh|ryPwrC= MmH3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMEi5NFAoRjJ3MEC4PVAxRC:jPh?=
SK-N-AS NGTrOZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37nclAuOTBizszN NIjufZo4OsLiaB?= NIG1dJVKSzVyPUGuO|EzyqEQvF5CpC=> MkfUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMEi5NFAoRjJ3MEC4PVAxRC:jPh?=
SK-N-DZ M{TW[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmixNE0yOCEQvF2= MVe3NuKhcA>? M2HFUWlEPTB;NT60PFXDqM7:TR?= MoXQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMEi5NFAoRjJ3MEC4PVAxRC:jPh?=
HepG2 M1\zcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWS0POKhcA>? M{nETGROW00EoB?= MYLJR|UxRTF|Lk[1xsDDucLiMD65NuKh|ryP MnTnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7OU[xN|YoRjJ2OUm2NVM3RC:jPh?=
A549 NX\BXot3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVexUWpNPDkEoHi= NYOzfm5[TE2VT9Mg MVjJR|UxRTJ2MT65xsDDucLiM{GuNlPDqM7:TR?= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl7NkGzOkc,OjR7OU[xN|Y9N2F-
MCF7 MkjZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7afGY1QMLiaB?= MXXEUXNQyqB? NXXoN|VOUUN3ME24NU4xQcLiwsJCpFE1NjJzwrFOwG0> NWrF[3RYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5PVYyOzZpPkK0PVk3OTN4PD;hQi=>
HL-60  MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELzR|A4OsLiaB?= MmO3TWM2OD1yLkGy5qCG|ryP MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl7M{CxOEc,OjR7OUOwNVQ9N2F-
HL-60[R] M1zOWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTHNYJEPzMEoHi= NVSz[3Q3UUN3ME2zMlEz6oDHzszN M1PGNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUmzNFE1Lz5{NEm5N|AyPDxxYU6=
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HeLa NHX6eWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3L2VWdKPTB;MD62OEDDuSByLkSg{txO M1zTVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzPFIyLz5{NEm1N|gzOTxxYU6=
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MO59J NXPC[XZmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo\VO{Bl M1v1[GlEPTB;MD6x5qCG|ryP M4HIOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzOVYyLz5{NEm1N|U3OTxxYU6=
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HL60 MmH0R5l1d3SxeHnjbZR6KGG|c3H5 MV:3NkBpenN? NXWxUoRMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4> M1TuOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUC3OFczLz5zOEWwO|Q4OjxxYU6=
HL60 MlTVRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NH23Rnk1QCCqcoO= MkG5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkOxOUDPxE1w MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDVzM{m3OEc,OTh3MUO5O|Q9N2F-
K562 MkjLRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MXW0PEBpenN? M2nMdWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iS{W2NkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6yO{DPxE1w NIfWR|E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEWxOFk4Oid-MUi1NVQ6PzJ:L3G+
KB MVHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M1L1OFQ5KGi{cx?= NYTzWIx1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD60NkDPxE1w M1PQSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUG0PVczLz5zOEWxOFk4OjxxYU6=
L02 MkDURY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYeyOWFEPDhiaILz NIq5XXFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFywNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUOg{txONg>? MljjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3MUS5O|IoRjF6NUG0PVczRC:jPh?=
DU145 ATCC HTB 81 NUTCXYI5S3m2b4TvfIlkcXS7IHHzd4F6 NVO5cohpPzJiaILz NX3JfWE5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hTFVzNEWgRXRESyCKVFKgPFEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuOUDPxE1w MlzJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3NUi0PVAoRjF6NUW4OFkxRC:jPh?=
K562 ATCC CCL 243 NXW4XYxtS3m2b4TvfIlkcXS7IHHzd4F6 MXy3NkBpenN? NG\TXGpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IFHUR2MhS0OOIEK0N{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND65JO69VS5? NGnmPJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW1PFQ6OCd-MUi1OVg1QTB:L3G+
MCF7 ATCC HTB 22 NUPwZYpoS3m2b4TvfIlkcXS7IHHzd4F6 Mo\yO|IhcHK| MUXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KEGWQ1OgTHRDKDJ{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOi5{IN88UU4> MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV3OES5NEc,OTh3NUi0PVA9N2F-
U251 RCB 0641 M17X[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXvveXM{PzJiaILz MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDVNlUyKFKFQjCwOlQyKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlUh|ryPLh?= NXH3SFFiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1OVg1QTBpPkG4OVU5PDlyPD;hQi=>
3LL CRL 1642 MXLDfZRwfG:6aXPpeJkh[XO|YYm= NEfHXlA1QCCqcoO= NID1fmtEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UA{VExiQ2LMJFE3PDJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQh|ryPLh?= Ml65QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3NUi0PVAoRjF6NUW4OFkxRC:jPh?=
L1210 ATCC CCL 219 M4TSeGN6fG:2b4jpZ4l1gSCjc4PhfS=> MmHLOFghcHK| NWPRPINWS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVDF{MUCgRXRESyCFQ1ygNlE6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlUh|ryPLh?= NVPOSVJNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1OVg1QTBpPkG4OVU5PDlyPD;hQi=>
SK-Hep1 NVXNOIRTS3m2b4TvfIlkcXS7IHHzd4F6 Mkm1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2suUGWyMTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0PU43KM7:TT6= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ|N{[4PEc,OTh4M{e2PFg9N2F-
HL60 NFHFRY9EgXSxdH;4bYNqfHliYYPzZZk> NUfwOGw5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCwMlIh|ryPLh?= MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ3MUe3NUc,OTh4NUG3O|E9N2F-
A549 NV\0dGhVS3m2b4TvfIlkcXS7IHHzd4F6 MknVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25ib3[gZ4VtdCCpcn;3eIgh[nliU2LCJI1mfGixZDygTWM2OCB;IEmuPVgh|ryPLh?= MljMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5OEK2OlgoRjF6N{iyOlY5RC:jPh?=
KB NU\HPFVqS3m2b4TvfIlkcXS7IHHzd4F6 NVnmUVdzS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0JiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIH;mJINmdGxiZ4Lve5RpKGK7IGPSRkBu\XSqb3SsJGlEPTBiPTCxOE4zKM7:TT6= NYDLVHVMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3PFI3PjhpPkG4O|gzPjZ6PD;hQi=>
A549 M2r5NGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWLlZlByPzJiaILz MYHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlM4KM7:TT6= MkCzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6NES0NlIoRjF6OES0OFIzRC:jPh?=
KB NHv4fHdEgXSxdH;4bYNqfHliYYPzZZk> M1e0elczKGi{cx?= MmDLR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuNlUh|ryPLh?= MofNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6NES0NlIoRjF6OES0OFIzRC:jPh?=
AGS NXTLT5BKS3m2b4TvfIlkcXS7IHHzd4F6 M2LBOlMh\GG7cx?= MYHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBS3Mh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuN|Yh|ryPLh?= NXXk[JN7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVMxPzRpPkG5NFE{ODd2PD;hQi=>
HL-60 M2XuemN6fG:2b4jpZ4l1gSCjc4PhfS=> NGr0NVU{KGSjeYO= M3jLZ2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhNNTZyIHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjhizszNMi=> NHvPcpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCxN|A4PCd-MUmwNVMxPzR:L3G+
J82 NXe1T|dzS3m2b4TvfIlkcXS7IHHzd4F6 NGW0PI0{KGSjeYO= MlLsR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTlgzKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlgh|ryPLh?= NV23WphoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVMxPzRpPkG5NFE{ODd2PD;hQi=>
MRC5 MWDDfZRwfG:6aXPpeJkh[XO|YYm= MXezJIRigXN? MlPXR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUXJEPSClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN{46KM7:TT6= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTBzM{C3OEc,OTlyMUOwO|Q9N2F-
SK-MES-1 MXvDfZRwfG:6aXPpeJkh[XO|YYm= M3;4e|Mh\GG7cx?= M{HzcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMNU2HUz2xJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkWg{txONg>? MmP5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMUOwO|QoRjF7MEGzNFc1RC:jPh?=
A375 M{DsXmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVrZNHlMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTN5NTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlkzKM7:TT6= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB|NkW4OEc,OTlyM{[1PFQ9N2F-
A549 M3;pemN6fG:2b4jpZ4l1gSCjc4PhfS=> M4rNVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT61NUDPxE1w MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB|NkW4OEc,OTlyM{[1PFQ9N2F-
HL60 M1PEOmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFP0eZNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJVDZyIHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuPFMh|ryPLh?= M{OzO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEO2OVg1Lz5zOUCzOlU5PDxxYU6=
THP1 Ml76R5l1d3SxeHnjbZR6KGG|c3H5 Mon6R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkG2JO69VS5? NFrSSVc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCzOlU5PCd-MUmwN|Y2QDR:L3G+
A549 M3fxfGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWLQZphiPzJiaILz MkS1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOU46KM7:TT6= MofmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO1NVQoRjF7MEWzOVE1RC:jPh?=
HL-60 MYrDfZRwfG:6aXPpeJkh[XO|YYm= MV63NkBpenN? MkS4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGwuPjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvOjVizszNMi=> MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{WxOEc,OTlyNUO1NVQ9N2F-
U937 NWSz[2xqS3m2b4TvfIlkcXS7IHHzd4F6 NH;LSmo4OiCqcoO= MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDVPVM4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlkzKM7:TT6= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{WxOEc,OTlyNUO1NVQ9N2F-
ACHN MoDMRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M4rvVVk3KGi{cx?= MWPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEGFSF6gZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwMUWg{txONg>? NYj4e|JwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PjdpPkG5NFU{PzZ5PD;hQi=>
CCRF-CEM NEPPT|hCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MWe5OkBpenN? MXzBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEOFUl[tR2VOKGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlIh|ryPLh?= M3\CeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|Y4Lz5zOUC1N|c3PzxxYU6=
CCRF-SB MUHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MWO5OkBpenN? Mn;hRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFQ2LGMXNDKGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlEh|ryPLh?= Ml7SQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3OlcoRjF7MEWzO|Y4RC:jPh?=
HeLa NETwXI5CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MlLMPVYhcHK| MmjPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHmeIVzKDl4IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|IN88UU4> MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e2O{c,OTlyNUO3Olc9N2F-
HT-29 NF3RN4NCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVW5OkBpenN? NGjIOIJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlUh|ryPLh?= M3zGT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|Y4Lz5zOUC1N|c3PzxxYU6=
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502713 NYXUdpZRSW62aXPhcoNmeiCjc4PhfS=> MWS0PEBpenN? M1jLVGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjC1NFI4OTNiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvOSEQvF2u M1;XVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEe0OFQ1Lz5{MUC3OFQ1PDxxYU6=
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DU145 MlnkRY51cWOjbnPldkBie3OjeR?= MoX3OFghcHK| MVfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygTWM2OCB;IEOuO{DPxE1w Ml\FQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
HCT15 NH6yUGhCdnSrY3HuZ4VzKGG|c3H5 MXm0PEBpenN? NEnJWHJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQSEQvF2u NY\jcFMxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwO|Q1PDRpPkKxNFc1PDR2PD;hQi=>
Hep2 M3nGd2FvfGmlYX7j[ZIh[XO|YYm= Mn;3OFghcHK| NUXNNIRbSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmeDJiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQSEQvF2u MofvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
IMR32 MW\BcpRq[2GwY3XyJIF{e2G7 M1LMTVQ5KGi{cx?= M{PYWGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDJUXI{OiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gOk4{KM7:TT6= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
PC3 M{\iUGFvfGmlYX7j[ZIh[XO|YYm= NXTaUIIxPDhiaILz NYXlNm16SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNk43KM7:TT6= NFj2b|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
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K562 NV6zWpJzS3m2b4TvfIlkcXS7IHHzd4F6 MUm3NkBpenN? NIC4OXlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEeLNUCgQUAyOi53OTFOwG0v NVzidVFORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNVUzOTBpPkKxNVE2OjFyPD;hQi=>
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HCT15 NV\1Ro9bS3m2b4TvfIlkcXS7IHHzd4F6 NIXvdIdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzNTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlA{KM7:TT6= NFvxUY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGxOVI1Pid-MkGxNVUzPDZ:L3G+
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A549 MW\DfZRwfG:6aXPpeJkh[XO|YYm= MWC3NkBpenN? M4\TNWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODB{NU[g{txONg>? MmWyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzNEWxN|koRjJzMUS1NVM6RC:jPh?=
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HepG2 M1\ZbmN6fG:2b4jpZ4l1gSCjc4PhfS=> MUTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNT64JO69VS5? NXvmWJpjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxO|Q1ODhpPkKxNVc1PDB6PD;hQi=>
MOLT3 MX3DfZRwfG:6aXPpeJkh[XO|YYm= MmTaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUW9NXDNiY3XscJMh[nliWGTUJIF{e2G7LDDJR|UxKD1iMD6wN{DPxE1w NVjPXJo1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxO|Q1ODhpPkKxNVc1PDB6PD;hQi=>
A549 MWHDfZRwfG:6aXPpeJkh[XO|YYm= NFfTeJREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGK7IGPSRkBie3OjeTygTWM2OCB;IEGuPFUh|ryPLh?= M{XET|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUiyNlU5Lz5{MUG4NlI2QDxxYU6=
SK-MEL-2 MVvDfZRwfG:6aXPpeJkh[XO|YYm= NIHNV3lEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUUy2PRVytNkBk\WyuczDifUBUWkJiYYPzZZktKEmFNUCgQUAyNjF5IN88UU4> MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTF6MkK1PEc,OjFzOEKyOVg9N2F-
SKOV3 MVvDfZRwfG:6aXPpeJkh[XO|YYm= MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{BjgSCVUlKgZZN{[XluIFnDOVAhRSBzLkixJO69VS5? NYL4W2dQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxPFIzPThpPkKxNVgzOjV6PD;hQi=>
XF498 MUnDfZRwfG:6aXPpeJkh[XO|YYm= MlLxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gXGY1QThiY3XscJMh[nliU2LCJIF{e2G7LDDJR|UxKD1iMT63NkDPxE1w NILx[3k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUG4NlI2QCd-MkGxPFIzPTh:L3G+
A549 NIPOZ4NEgXSxdH;4bYNqfHliYYPzZZk> NIT5dZY{KGSjeYO= MXvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKxMlQh|ryPLh?= MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ5N{[1OUc,OjF{N{e2OVU9N2F-
HCT116 M1XFZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXSzJIRigXN? NYjpTmc2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHzd4V{e2WmIHHzJINmdGxiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF|LkWg{txONg>? MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ5N{[1OUc,OjF{N{e2OVU9N2F-
HepG2 NFv0W4tEgXSxdH;4bYNqfHliYYPzZZk> NVvJNWJ6OyCmYYnz Ml\CR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEBoem:5dHigbY5pcWKrdHnvckBi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOE46KM7:TT6= M17mOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMke3OlU2Lz5{MUK3O|Y2PTxxYU6=
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DU145 M4r4emN6fG:2b4jpZ4l1gSCjc4PhfS=> MUGyJIRigXN? NHHW[4hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBFXTF2NTDj[YxteyCjZoTldkAzKGSjeYOgZpkh[2WubDDjc5VvfGmwZzDrbZQuQCCjbnHsfZNqeyxiSVO1NEA:KDFwMkGg{txONg>? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyM{[1Okc,OjJ3MEO2OVY9N2F-
HCT15 NXX6NWtqS3m2b4TvfIlkcXS7IHHzd4F6 NUf5dpZvOiCmYYnz NXWwOpJHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUWgZ4VtdHNiYX\0[ZIhOiCmYYnzJIJ6KGOnbHygZ492dnSrbnegb4l1NThiYX7hcJl{cXNuIFnDOVAhRSBzLkG3JO69VS5? Ml\1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3MEO2OVYoRjJ{NUCzOlU3RC:jPh?=
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A549 NV[1[W57SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MonURY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjJizszNMi=> M1;te|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MkG2NFE5Lz5{NkKxOlAyQDxxYU6=
HepG2 M2rMNWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIxNjlizszNMi=> Mk\1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ{MU[wNVgoRjJ4MkG2NFE5RC:jPh?=
A549 NH\yWHNEgXSxdH;4bYNqfHliYYPzZZk> MnfVOFghcHK| MWDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCpcn;3eIghcW6ldXLheIVlKG[xcjC0PEBpenNiYomgTI9m[2i|dDDhd5NigSxiSVO1NEA:KDBwNEig{txONg>? NXGzZpBoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yNlU6ODVpPkK2NlI2QTB3PD;hQi=>
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HepG2 M4fST2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M2W0TVczKGi{cx?= MUTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCVUlKgZZN{[XluIFnDOVAhRSB|MDFOwG0v NF;DU5g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK5NVA{Pyd-Mk[yPVExOzd:L3G+
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MDA-MB-435 MnrqRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYS3NkBpenN? MlnWRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPRFGtUWIuPDN3IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAyNjdizszNMi=> M3XvWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MkmxNFM4Lz5{NkK5NVA{PzxxYU6=
PC3 NUTmXmlFSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NGDk[2k4OiCqcoO= M{nkSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCVUlKgZZN{[XluIFnDOVAhRSBzIN88UU4> MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ7MUCzO{c,OjZ{OUGwN|c9N2F-
A549 NYLoSoUyS3m2b4TvfIlkcXS7IHHzd4F6 MVy0PEBpenN? NFXxR3lEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{QC53IN88UU4> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ7Mk[yPEc,OjZ{OUK2Nlg9N2F-
DU145 NHnTbHdEgXSxdH;4bYNqfHliYYPzZZk> NVnHOXl1PDhiaILz NIq0T|FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBFXTF2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPS5{MTFOwG0v NIfkSlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK5NlYzQCd-Mk[yPVI3Ojh:L3G+
HGC M2XMN2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3;RVlQ5KGi{cx?= MlTlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGdEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE46KM7:TT6= NELEUpM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK5NlYzQCd-Mk[yPVI3Ojh:L3G+
MDA-MB-231 NFzWdHVEgXSxdH;4bYNqfHliYYPzZZk> NXf3XIlJPDhiaILz M{\R[2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IES5MlM2KM7:TT6= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ7Mk[yPEc,OjZ{OUK2Nlg9N2F-
RWPE1 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MmPROFghcHK| M4nGUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHJYWEVzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPy54NDFOwG0v NYjPVYJ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yPVI3OjhpPkK2NlkzPjJ6PD;hQi=>
HCT15 MWHDfZRwfG:6aXPpeJkh[XO|YYm= MnXKNkBl[Xm| M2PWU2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDF3IHPlcIx{KG2nYYP1doVlKGGodHXyJFIh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjV2IN88UU4> MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjN|NES5PUc,OjZ|M{S0PVk9N2F-
HeLa M13wTGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWOyJIRigXN? MVrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJI1m[XO3cnXkJIFnfGW{IEKg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlYh|ryPLh?= M3P1elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{O0OFk6Lz5{NkOzOFQ6QTxxYU6=
T47D M1HJUWN6fG:2b4jpZ4l1gSCjc4PhfS=> Moj0NkBl[Xm| M4r2ZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHQ1P0RiY3XscJMhdWWjc4Xy[YQh[W[2ZYKgNkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFkvOjhizszNMi=> NX3QSJluRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zN|Q1QTlpPkK2N|M1PDl7PD;hQi=>
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DU145 Ml7WR5l1d3SxeHnjbZR6KGG|c3H5 NEnLXWMzKGSjeYO= NECxR4tEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBFXTF2NTDj[YxteyCjZoTldkAzKGSjeYOgZpkhS0ONODDhd5NigSxiSVO1NEA:KDF|LkGg{txONg>? MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjN4MUezO{c,OjZ|NkG3N|c9N2F-
HCT15 MWjDfZRwfG:6aXPpeJkh[XO|YYm= NXP4b3ptOiCmYYnz MoTIR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JGNEUzhiYYPzZZktKEmFNUCgQUAzNjZizszNMi=> M1\MPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{[xO|M4Lz5{NkO2NVc{PzxxYU6=
MCF10A MWnDfZRwfG:6aXPpeJkh[XO|YYm= NI\s[5AzKGSjeYO= MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2YyOEFiY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JGNEUzhiYYPzZZktKEmFNUCgQUAyOC5zNDFOwG0v NV3qToFIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zOlE4OzdpPkK2N|YyPzN5PD;hQi=>
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HepG2 M1iwRWN6fG:2b4jpZ4l1gSCjc4PhfS=> MlvuOFghcHK| NWLnSZNkS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN|Lkm4JO69VS5? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjN7N{O5N{c,OjZ|OUezPVM9N2F-
MOLT3 M17sWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MXW0PEBpenN? MmnKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUW9NXDNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHhVXCCjc4PhfUwhUUN3MDC9JFAvODRzIN88UU4> MoDPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ|OUezPVMoRjJ4M{m3N|k{RC:jPh?=
A549 NHi4bXpEgXSxdH;4bYNqfHliYYPzZZk> NVPXWIl6PDhiaILz NUP3[4RGS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB2ODDodpMh[nlicnXzZZp2emmwIHHzd4F6NCCLQ{WwJF0hOS55IN88UU4> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjV7Mki5O{c,OjZ3OUK4PVc9N2F-
DLD1 NEfI[2VEgXSxdH;4bYNqfHliYYPzZZk> M{O2PFQ5KGi{cx?= NWHaW5NpS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hTEyGMTDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB2ODDodpMh[nlicnXzZZp2emmwIHHzd4F6NCCLQ{WwJF0hOiEQvF2u Mo\aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3OUK4PVcoRjJ4NUmyPFk4RC:jPh?=
A549 MYHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M37Rd|I1KHSxIEeyJIhzew>? MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhOjRidH:gO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQCEQvF2u MlTCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3OUW4O|UoRjJ4NUm1PFc2RC:jPh?=
CAKI-1 MoDTRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYCyOEB1dyB5MjDodpM> Mn\iRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFQVvJMVEh[2WubIOgZYZ1\XJiMkSgeI8hPzJiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDFwMTFOwG0v M3fqSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NUm1PFc2Lz5{NkW5OVg4PTxxYU6=
HCT116 MV\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkL2NlQhfG9iN{KgbJJ{ M1\nU2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIFnfGW{IEK0JJRwKDd{IHjyd{BjgSCVUlKgZZN{[XluIFnDOVAhRSB|LkOg{txONg>? NIS5Opc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkW5OVg4PSd-Mk[1PVU5PzV:L3G+
HCT116 NX:1OJlySW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnuwOFghcHK| NVnxZ2NHSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFIvOyEQvF2u NYfWS3lJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[1PVU5PzVpPkK2OVk2QDd3PD;hQi=>
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