Rotigotine

For research use only.

Catalog No.S4274

1 publication

Rotigotine Chemical Structure

CAS No. 99755-59-6

Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.

Selleck's Rotigotine has been cited by 1 publication

Purity & Quality Control

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Biological Activity

Description Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.
Targets
Dopamine receptor [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 63 mg/mL (199.7 mM)
Ethanol 63 mg/mL (199.7 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 315.47
Formula

C19H25NOS

CAS No. 99755-59-6
Storage powder
in solvent
Synonyms N/A
Smiles CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation ()
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02728947 Completed Drug: ROTIGOTINE Parkinson''s Disease Luye Pharma Group Ltd. May 2016 Phase 1
NCT02070796 Completed Drug: Rotigotine PR2.2.1|Drug: Rotigotine PR2.1.1 Healthy UCB Pharma SA|UCB Pharma February 2014 Phase 1
NCT01675024 Completed Drug: Rotigotine Period 1|Drug: Rotigotine Period 2 Healthy UCB Pharma August 2012 Phase 1
NCT02786667 Unknown status Drug: Rotigotine|Drug: Placebo Parkinson Disease|Apathy University Hospital Grenoble June 2012 Phase 3
NCT01565018 Completed Drug: Rotigotine PR 2.1.4|Drug: Rotigotine PR 2.2.1 Healthy Volunteers UCB Pharma|Otsuka Pharmaceutical Co. Ltd. March 2012 Phase 1
NCT01536015 Terminated Drug: Rotigotine|Drug: Placebo Advanced Parkinson''s Disease UCB Pharma January 2012 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Dopamine Receptor Signaling Pathway Map

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