Metoclopramide HCl

For research use only.

Catalog No.S4289

1 publication

Metoclopramide HCl Chemical Structure

CAS No. 7232-21-5

Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.

Selleck's Metoclopramide HCl has been cited by 1 publication

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Biological Activity

Description Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.
D2 receptor [1]



Solubility (25°C)

In vitro DMSO 67 mg/mL warmed (199.25 mM)
Water 67 mg/mL (199.25 mM)
Ethanol 67 mg/mL (199.25 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 336.26


CAS No. 7232-21-5
Storage powder
in solvent
Synonyms N/A
Smiles CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05008926 Not yet recruiting Drug: Naloxegol|Drug: Placebo Brain Injuries University Hospital Brest October 2021 Phase 3
NCT04771481 Not yet recruiting Drug: Metoclopramide|Drug: Normal Saline 10 mL Injection Acute Upper Gastrointestinal Bleeding|Effect of Drug King Chulalongkorn Memorial Hospital March 2021 Phase 4
NCT04748133 Recruiting Device: acupuncture needles|Other: placebo Treatment Complication Zagazig University February 20 2021 Not Applicable
NCT02466984 Completed Drug: metoclopramide intravenous Nausea|Vomiting University Hospital Bordeaux July 2016 Phase 3

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID