For research use only.
Catalog No.S5191 Synonyms: AMG073, Sensipar, Cin
CAS No. 226256-56-0
Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.
Purity & Quality Control
Choose Selective Calcium Channel Inhibitors
|Description||Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.|
|Storage||2 years -20°C liquid|
|Synonyms||AMG073, Sensipar, Cin|
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03913117||Not yet recruiting||Biological: pNGVL4aCRTE6E7L2|Biological: TA-CIN||ASC-US|LSIL||PapiVax Biotech Inc.|University of Alabama at Birmingham|Johns Hopkins University||December 31 2021||Phase 1|
|NCT04929899||Not yet recruiting||Behavioral: Bright Ideas - CIN Training||Acute Lymphoblastic Leukemia (ALL)||The Hospital for Sick Children|Rutgers Cancer Institute of New Jersey|Inova Fairfax Hospital|Children''s Hospital Los Angeles||September 2021||Not Applicable|
|NCT05022511||Not yet recruiting||Behavioral: Screening status||Uterine Cervical Cancer|Uterine Cervix Cancer|Uterine Cervical Neoplasm|Colorectal Neoplasms|Colorectal Cancer|Colorectal Carcinoma|Mass Screening|Early Detection of Cancer||University of Aarhus||September 2021||Not Applicable|
|NCT04988685||Recruiting||Device: Sirolimus Eluting Balloon||Coronary Disease|Coronary Artery Disease|Coronary Restenosis|Coronary Arteriosclerosis|Coronary Artery Calcification|Stable Chronic Angina|Angina Pectoris|Angina Stable|Angina Unstable|Stent Thrombosis||Luzerner Kantonsspital||August 1 2021||--|
|NCT05003505||Recruiting||Other: Follow up||Intestinal Microbiota|Vaginal Microbiota|HPV Infection||Fujian Maternity and Child Health Hospital||July 1 2021||--|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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