Cinacalcet

Catalog No.S5191 Synonyms: AMG073, Sensipar, Cin

For research use only.

Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.

Cinacalcet Chemical Structure

CAS No. 226256-56-0

Selleck's Cinacalcet has been cited by 1 Publication

Purity & Quality Control

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Biological Activity

Description Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.
Targets
CaR [1]

Protocol (from reference)

Chemical Information

Molecular Weight 357.41
Formula

C22H22F3N

CAS No. 226256-56-0
Storage 2 years -20°C liquid

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03913117 Not yet recruiting Biological: pNGVL4aCRTE6E7L2|Biological: TA-CIN ASC-US|LSIL PapiVax Biotech Inc.|University of Alabama at Birmingham|Johns Hopkins University December 31 2022 Phase 1
NCT05283421 Not yet recruiting Diagnostic Test: Estrogen|Diagnostic Test: Placebo Cervical Cancer University of Aarhus December 1 2022 Not Applicable
NCT05413811 Not yet recruiting Drug: 5 Fluorouracil (5 FU) Cream|Drug: Placebo Cervical Cancer|CIN2|CIN3|Human Immunodeficiency Virus|Human Papillomavirus UNC Lineberger Comprehensive Cancer Center|National Cancer Institute (NCI) October 20 2022 Not Applicable
NCT05132803 Not yet recruiting Drug: HPV 16 TA-CIN Recurrent Human Papillomavirus Type 16 Associated Cancer Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins August 2022 Phase 1
NCT05237193 Recruiting Diagnostic Test: The level of CIN Biliary Tract Neoplasms|Pancreatic Carcinoma|Gallbladder Cancer|Pancreatic Head Carcinoma Xinhua Hospital Shanghai Jiao Tong University School of Medicine|Shanghai Zhongshan Hospital|Ruijin Hospital|Changhai Hospital|Shanghai Changzheng Hospital|Eastern Hepatobiliary Surgery Hospital|First Affiliated Hospital Xi''an Jiaotong University|Jiangsu Provincial People''s Hospital|Third Affiliated Hospital Sun Yat-Sen University|First Affiliated Hospital of Zhejiang University|The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School|Second Hospital of Jilin University|West China Hospital|The Southwest Hospital of AMU|Affiliated Hospital of North Sichuan Medical College|Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University July 2022 --

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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