Cinacalcet

For research use only.

Catalog No.S5191 Synonyms: AMG073, Sensipar, Cin

Cinacalcet Chemical Structure

CAS No. 226256-56-0

Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.

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Biological Activity

Description Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.
Targets
CaR [1]
()

Protocol

Solubility (25°C)

Chemical Information

Molecular Weight 357.41
Formula

C22H22F3N

CAS No. 226256-56-0
Storage 2 years -20°C liquid
Synonyms AMG073, Sensipar, Cin

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03913117 Not yet recruiting Biological: pNGVL4aCRTE6E7L2|Biological: TA-CIN ASC-US|LSIL PapiVax Biotech Inc.|University of Alabama at Birmingham|Johns Hopkins University December 31 2021 Phase 1
NCT04929899 Not yet recruiting Behavioral: Bright Ideas - CIN Training Acute Lymphoblastic Leukemia (ALL) The Hospital for Sick Children|Rutgers Cancer Institute of New Jersey|Inova Fairfax Hospital|Children''s Hospital Los Angeles September 2021 Not Applicable
NCT05022511 Not yet recruiting Behavioral: Screening status Uterine Cervical Cancer|Uterine Cervix Cancer|Uterine Cervical Neoplasm|Colorectal Neoplasms|Colorectal Cancer|Colorectal Carcinoma|Mass Screening|Early Detection of Cancer University of Aarhus September 2021 Not Applicable
NCT04988685 Recruiting Device: Sirolimus Eluting Balloon Coronary Disease|Coronary Artery Disease|Coronary Restenosis|Coronary Arteriosclerosis|Coronary Artery Calcification|Stable Chronic Angina|Angina Pectoris|Angina Stable|Angina Unstable|Stent Thrombosis Luzerner Kantonsspital August 1 2021 --
NCT05003505 Recruiting Other: Follow up Intestinal Microbiota|Vaginal Microbiota|HPV Infection Fujian Maternity and Child Health Hospital July 1 2021 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Calcium Channel Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID