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Tetracaine HCl
Synonyms: Amethocaine hydrochloride
Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
Tetracaine HCl Chemical Structure
CAS: 136-47-0
Selleck's Tetracaine HCl has been cited by 1 publication
Purity & Quality Control
Batch:
Purity:
100%
100
Tetracaine HCl Related Products
| Related Targets | Cav 2.2 | Click to Expand |
|---|---|---|
| Related Compound Libraries | FDA-approved Drug Library Natural Product Library Ion Channel Ligand Library Exosome Secretion Related Compound Library Calcium Channel Blocker Library | Click to Expand |
Signaling Pathway
Choose Selective Calcium Channel Inhibitors
Biological Activity
| Description | Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. | |
|---|---|---|
| Targets |
|
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT04794842 | Active not recruiting | Intratympanic Steroid Injection|Idiopathic Sudden Sensorineural Hearing Loss|Meniere Disease |
Our Lady of the Lake Hospital|Louisiana State University Health Sciences Center - New Orleans |
August 1 2021 | Early Phase 1 |
| NCT01952990 | Completed | Anesthesia |
St. Renatus LLC|Triligent International|Analytical Bio-Chemistry Laboratories Inc.|Rho Inc. |
September 2013 | Phase 2 |
| NCT01304316 | Completed | Anesthesia |
St. Renatus LLC|Ground Zero Pharmaceuticals|Rho Inc. |
September 2010 | Phase 2 |
| NCT00747669 | Suspended | Pain |
ZARS Pharma Inc. |
September 2008 | Phase 4 |
Chemical Information & Solubility
| Molecular Weight | 300.82 | Formula | C15H24N2O2.HCl |
| CAS No. | 136-47-0 | SDF | Download Tetracaine HCl SDF |
| Smiles | CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl | ||
| Storage (From the date of receipt) | |||
|
In vitro |
DMSO : 60 mg/mL ( (199.45 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.) Water : 60 mg/mL Ethanol : 30 mg/mL |
Molecular Weight Calculator |
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In vivo Add solvents to the product individually and in order. |
In vivo Formulation Calculator |
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Preparing Stock Solutions
Molarity Calculator
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
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%
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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