Alizapride HCl

For research use only.

Catalog No.S4257

Alizapride HCl Chemical Structure

CAS No. 59338-87-3

Alizapride HCl is a dopamine receptor antagonist used for the theropy of nausea and vomiting.

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Biological Activity

Description Alizapride HCl is a dopamine receptor antagonist used for the theropy of nausea and vomiting.
Dopamine receptor [1]
In vitro

Alizapride has a N-allyl moiety which potentially could undergo N-deallylation and/or epoxidation reactions, the formation of chemically reactive metabolites can be expected. [1]

In vivo Alizapride demonstrates little toxicity (particularly after parenteral administration) in mice and rats. Alizapride is mainly excreted as unmodified drug after oral or parenteral administration; however, a share of about 25% undergoes metabolic transformation before deletion. [1] Alizapride (5 mg/kg, s.c.) antagonizes the decrease in gastrointestinal transit induced by the above doses of Apomorphine in the rat. [2]


Solubility (25°C)

In vitro Water 70 mg/mL (198.95 mM)
DMSO 42 mg/mL (119.37 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 351.83


CAS No. 59338-87-3
Storage powder
in solvent
Synonyms N/A

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID