Adenosine Receptor

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S8314 5-Iodotubercidin <1 mg/mL 78 mg/mL <1 mg/mL
S2790 Istradefylline <1 mg/mL 6 mg/mL <1 mg/mL
S8575 A2AR antagonist 1 <1 mg/mL 61 mg/mL <1 mg/mL
S5427 Alloxazine -1 mg/mL 2 mg/mL -1 mg/mL
S4932 Proxyphylline -1 mg/mL 47 mg/mL -1 mg/mL
S3988 Theophylline-7-acetic acid -1 mg/mL 47 mg/mL -1 mg/mL
S8105 ZM241385 <1 mg/mL 67 mg/mL <1 mg/mL
S8104 SCH58261 <1 mg/mL 69 mg/mL <1 mg/mL
S7588 Reversine <1 mg/mL 5 mg/mL <1 mg/mL
S2153 CGS 21680 HCl <1 mg/mL 100 mg/mL <1 mg/mL
S1647 Adenosine <1 mg/mL 12 mg/mL <1 mg/mL
S5358 Regadenoson <1 mg/mL 56 mg/mL 56 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8314

5-Iodotubercidin

5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.

S2790

Istradefylline

Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.

S8575

A2AR antagonist 1

A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively.

S5427New

Alloxazine

Alloxazine is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.

S8720New

AZD-4635 (HTL1071)

AZD-4635 (HTL1071) is an oral A2AR antagonist that binds to human A2AR with a Ki of 1.7 nM and with > 30-fold selectivity over other adenosine receptors.

S4932New

Proxyphylline

Proxyphylline is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).

S3988New

Theophylline-7-acetic acid

Theophylline-7-acetic acid (Acefylline), acting as an adenosine receptor antagonist, is a stimulant drug of the xanthine chemical class.

S8105

ZM241385

ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.

S8104

SCH58261

SCH 58261 is a potent and selective A2a adenosine receptor antagonist with Ki of 2.3 nM and 2 nM for rat A2a and bovine A2a, respectively.

S7588

Reversine

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.

S2153

CGS 21680 HCl

CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.

S1647

Adenosine

Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.

S5358New

Regadenoson

Regadenoson is a selective A2A adenosine receptor agonist with coronary vasodilating activity.