Home GPCR & G Protein Adenosine Receptor agonist N6-Cyclopentyladenosine For research use only.

N6-Cyclopentyladenosine

N6-Cyclopentyladenosine is an adenosine derivative and a potent adenosine receptor agonist with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.

N6-Cyclopentyladenosine Chemical Structure

N6-Cyclopentyladenosine Chemical Structure

CAS: 41552-82-3

Purity & Quality Control

Batch: E445001 DMSO] 67 mg/mL] false] Ethanol] 67 mg/mL] false] Water] 4 mg/mL] false Purity: 99.23%
99.23

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Biological Activity

Description N6-Cyclopentyladenosine is an adenosine derivative and a potent adenosine receptor agonist with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
Targets
A1 [1] A3 [1] A2A [1]
2.3 nM(Ki) 43 nM(Ki) 790 nM(Ki)

Chemical Information & Solubility

Molecular Weight 335.36 Formula

C15H21N5O4
CAS No. 41552-82-3 SDF Download N6-Cyclopentyladenosine SDF
Storage (From the date of receipt) Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

In vitro
Batch:

DMSO : 67 mg/mL ( (199.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 67 mg/mL

Water : 4 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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