Home GPCR & G Protein Adenosine Receptor agonist N6-Cyclopentyladenosine

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N6-Cyclopentyladenosine Adenosine Receptor agonist

Cat.No.E4450

N6-Cyclopentyladenosine is an adenosine derivative and a potent adenosine receptor agonist with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. It acts as an anticonvulsant and might exhibit protective actions against (AMPH)-induced seizures.
N6-Cyclopentyladenosine Adenosine Receptor agonist Chemical Structure

Chemical Structure

Molecular Weight: 335.36

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Quality Control

Batch: E445001 DMSO]67 mg/mL]false]Ethanol]67 mg/mL]false]Water]4 mg/mL]false Purity: 99.23%
99.23

Chemical Information, Storage & Stability

Molecular Weight 335.36 Formula

C15H21N5O4

 Storage (From the date of receipt)
CAS No. 41552-82-3 Download SDF Storage of Stock Solutions

Solubility

In vitro
Batch:

DMSO : 67 mg/mL (199.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 67 mg/mL

Water : 4 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Targets/IC50/Ki
A1 [1]
2.3 nM(Ki)
A3 [1]
43 nM(Ki)
A2A [1]
790 nM(Ki)
References

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