SCH-442416

Catalog No.S2945

For research use only.

SCH-442416 is a selective antagonist of adenosine A2A receptor that binds to human and rat adenosine A2A receptors with Ki of 0.048 nM and 0.5 nM, respectively.

SCH-442416 Chemical Structure

CAS No. 316173-57-6

Purity & Quality Control

Choose Selective Adenosine Receptor Inhibitors

Biological Activity

Description SCH-442416 is a selective antagonist of adenosine A2A receptor that binds to human and rat adenosine A2A receptors with Ki of 0.048 nM and 0.5 nM, respectively.
Targets
Human A2A receptor [1]
(Cell-free assay)
Rat A2A receptor [1]
(Cell-free assay)
0.048 nM(Ki) 0.5 nM(Ki)

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 389.41
Formula

C20H19N7O2

CAS No. 316173-57-6
Storage 3 years -20°C powder
2 years -80°C in solvent

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT00531193 Completed Drug: BIIB014|Other: [11C]SCH442416 Healthy Biogen September 2007 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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