Name: Adenosine
Brand: Selleck Chemicals
SKU: S1647
Availability: InStock
Rating: 5 (12 reviews)

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Quality Control

Batch: Purity: 99.95%

99.95

Related Targets	CXCR Hedgehog/Smoothened PKA Adrenergic Receptor AChR 5-HT Receptor Histamine Receptor Dopamine Receptor Ras KRas
Other Adenosine Receptor Inhibitors	Reversine CGS 21680 HCl ZM241385 SCH58261 Ciforadenant (CPI-444) A2AR antagonist 1 Etrumadenant (AB928) Imaradenant (AZD4635) DPCPX SCH-442416

Solubility

In vitro
Batch:

DMSO : 27 mg/mL (101.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	1.350mg/ml (5.05mM)	Taking the 1 mL working solution as an example, add 50 μL of 27 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.675mg/ml (2.53mM)	Taking the 1 mL working solution as an example, add 50 μL of 13.5 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	267.24	Formula	C₁₀H₁₃N₅O₄	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	58-61-7	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	N/A			SMILES	C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-12-02)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT04666454	RECRUITING	Takotsubo Syndrome	Vastra Gotaland Region	2020-12-14	PHASE4
NCT07249034	NOT_YET_RECRUITING	Epilepsy; Drug-resistant Focal Epilepsy; Healthy Controls	Hospices Civils de Lyon	2026-08-07
NCT06921720	RECRUITING	Phosphate Diabetes; X-linked Hypophosphatemia	Hospices Civils de Lyon	2025-05-16
NCT05309655	ACTIVE_NOT_RECRUITING	Breast Cancer; Triple Negative Breast Cancer; Cardiovascular Complications	Duke University	2022-09-02
NCT05272709	RECRUITING	Advanced Solid Tumors	Cancer Research UK	2022-01-19	PHASE1; PHASE2
NCT07296354	NOT_YET_RECRUITING	Neuropathic Pain	Egyptian International Pharmaceutical Industries Co	2026-01-10	PHASE4

Tech Support

Handling Instructions

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Adenosine Adenosine Receptor agonist

Chemical Structure

Molecular Weight: 267.24