Mitomycin C

For research use only.

Catalog No.S8146

22 publications

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Selleck's Mitomycin C has been cited by 22 publications

Mol Cell, 2020, 30 pii: S1097-2765(20)30232-X

PubMed: 32359443 ( click the link to review the publication )

Cell Death Dis, 2020, 14;11(4):230

PubMed: 32286266 ( click the link to review the publication )

Sci Rep, 2020, 10(1):931

PubMed: 31969633 ( click the link to review the publication )

Cancer Cell Int, 2020, 19;20:58

PubMed: 32099531 ( click the link to review the publication )

Front Oncol, 2020, 10:10

PubMed: 32047721 ( click the link to review the publication )

Clin Cancer Res, 2019, 25(6):1957-1969

PubMed: 30482778 ( click the link to review the publication )

Cell Rep, 2019, 27(11):3331-3344

PubMed: 31189115 ( click the link to review the publication )

Protein Cell, 2019, 10.1007/s13238-019-0610-7

PubMed: 30796637 ( click the link to review the publication )

J Cell Physiol, 2019, 10.1002/jcp.28810

PubMed: 31093976 ( click the link to review the publication )

Front Physiol, 2019, 10:24

PubMed: 30745880 ( click the link to review the publication )

Sci China Life Sci, 2019, 10.1007

PubMed: 31872377 ( click the link to review the publication )

Br J Surg, 2019, 10.1002/bjs.11206

PubMed: 31197820 ( click the link to review the publication )

Int J Mol Sci, 2018, 20(1)

PubMed: 30591689 ( click the link to review the publication )

Biomed Pharmacother, 2018, 101:107-114

PubMed: 29477470 ( click the link to review the publication )

Chem Biol Interact, 2018, 296:26-33

PubMed: 30217479 ( click the link to review the publication )

BMC Cancer, 2018, 18(1):426

PubMed: 29661159 ( click the link to review the publication )

Cancer Sci, 2018, 109(11):3450-3460

PubMed: 30191636 ( click the link to review the publication )

Cancer Manag Res, 2018, 10:6791-6802

PubMed: 30588088 ( click the link to review the publication )

Sci Adv, 2018, 4(9):eaar4666

PubMed: 30263952 ( click the link to review the publication )

Oncogene, 2017, 10.1038/onc.2017.6

PubMed: 28218905 ( click the link to review the publication )

Oncol Lett, 2017, 14(6):8035-8041

PubMed: 29344246 ( click the link to review the publication )

Oncotarget, 2017, 8(70):115164-115178

PubMed: 29383150 ( click the link to review the publication )

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Targets

DNA synthesis ^[1]

In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. ^[1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. ^[2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. ^[3]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
human NTERA-S-cl-D1 cell	M33uV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NF3jcoVKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlIy\S1yNTFOwG0>	MkDyV2FPT0WU
human MOLT-4 cell	M{X1UWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MkjqTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI2\S1yNTFOwG0>	NETxemdUSU6JRWK=
human J82 cell	MoLzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NUjJd3pZUW6qaXLpeIlwdiCxZjDoeY1idiCMOEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlEyQSCwTR?=	MnnjV2FPT0WU
human 697 cell	M4G3Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVTJcohq[mm2aX;uJI9nKGi3bXHuJFY6PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G778{MJGlEPTB;MD6xNlghdk1?	MojGV2FPT0WU
human KYSE-510 cell	MkC3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVjJcohq[mm2aX;uJI9nKGi3bXHuJGt[W0VvNUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDlibl2=	NUXsfodwW0GQR1XS
human NCI-H2170 cell	NWO3dnZCT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NF74fVdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE4OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwMUWxJI5O	MV7TRW5ITVJ?
human BE-13 cell	NEPCTmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NGXVPVJKdmirYnn0bY9vKG:oIHj1cYFvKEKHLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPjdibl2=	NUDCdnJ7W0GQR1XS
human LC-2-ad cell	Mn;zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Ml\hTY5pcWKrdHnvckBw\iCqdX3hckBNSy1{LXHkJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDlibl2=	MUjTRW5ITVJ?
human IMR-5 cell	NWTR[mN1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MXHJcohq[mm2aX;uJI9nKGi3bXHuJGlOWi13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6zNFghdk1?	NEHyPWZUSU6JRWK=
human EW-16 cell	NUDz[nNYT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NES1OXJKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{OSCwTR?=	M1vXdHNCVkeHUh?=
human MC-IXC cell	MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MkHtTY5pcWKrdHnvckBw\iCqdX3hckBOSy2LWFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY{QCEQvF2=	NFmzdmFUSU6JRWK=
human SW872 cell	NUnOclJrT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MofjTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuOlc3KM7:TR?=	NXrUXo5UW0GQR1XS
human NCI-H2228 cell	Mk\jS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NXm5blF{UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke5OkDPxE1?	NIHPTm5USU6JRWK=
K562 leukemia cells	MknsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NITlc3dKdiC4aYTyc{BqdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUzV4MjDs[ZVs\W2rYTDj[YxteyxiSVO1NF0yKG6P	MVSxNlY6QTN6Nh?=
human NALM-6 cell	NEPJcohIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NF3abVBKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvODdibl2=	MYPTRW5ITVJ?
AA8 cells	MlnZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?	NFLzOFQ1KGh?	M{fiOWlvcGmkaYTvdpkh[WO2aY\peJkhd2ZiY3;tdI92dmRiZn;yJGFCQCClZXzsd{B1dyC{ZXT1Z4Uh[2WubDDk[Y5{cXS7IHL5JFUxLSBqZYjwc5Nm\CC2bzDjc41xd3WwZDDmc5IhPCCqb4Xyd{k>	M1n1eVI6ODl5NEG=
human ES4 cell	NGD0XXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MoXJTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O	MV7TRW5ITVJ?
human KE-37 cell	MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NELncVZKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43PCCwTR?=	M334e3NCVkeHUh?=
human IST-MEL1 cell	MmnIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYG5PJhCUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwNkigcm0>	M3ns[3NCVkeHUh?=
human ES8 cell	MkXaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3;RfWlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT63NUBvVQ>?	NVrTc4VwW0GQR1XS
human MV-4-11 cell	MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MoHkTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44OyCwTR?=	NH3hZZpUSU6JRWK=
human 639-V cell	M2Hpemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NV[wOZhLUW6qaXLpeIlwdiCxZjDoeY1idiB4M{mtWkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPzZibl2=	MUPTRW5ITVJ?
human OCI-AML2 cell	M4HIVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3z4bmlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh7IH7N	NXHkeWQ4W0GQR1XS
human SK-LU-1 cell	NYfaU45{T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NF;kW4ZKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzVMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ{IH7N	MXzTRW5ITVJ?
human PSN1 cell	M1LGRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NFzV[VhKdmirYnn0bY9vKG:oIHj1cYFvKFCVTkGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlU2KG6P	MV;TRW5ITVJ?
human REH cell	NHzjcphIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NHv6W4lKdmirYnn0bY9vKG:oIHj1cYFvKFKHSDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKuOVUhdk1?	M2rGOXNCVkeHUh?=
human SBC-5 cell	MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NI\SW3FKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?=	NUjDemJCW0GQR1XS
human HT-3 cell	M1HDUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MlrOTY5pcWKrdHnvckBw\iCqdX3hckBJXC1\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj65N{BvVQ>?	M3nneHNCVkeHUh?=
human SIG-M5 cell	NXfFbmJlT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M4HhVmlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42OiCwTR?=	M1e0eHNCVkeHUh?=
human ES7 cell	NIPLSXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MUjJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNwNkWgcm0>	MUjTRW5ITVJ?
human CHP-212 cell	NXrLPIk4T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MUXJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1{MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlM4KG6P	NX74OVBuW0GQR1XS
human P12-ICHIKAWA cell	NG\GfmVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NYDrUXlwUW6qaXLpeIlwdiCxZjDoeY1idiCSMUKtTWNJUUuDV1GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlc6KG6P	M2DINnNCVkeHUh?=
human HUTU-80 cell	M4m1S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3HMVmlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDNibl2=	M2j0eXNCVkeHUh?=
human P30-OHK cell	NVnFWnE1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MlL1TY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45PCCwTR?=	MnW5V2FPT0WU
human NCI-H1651 cell	MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[1NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTlibl2=	NGK1NYRUSU6JRWK=
Chinese hamster V-C8 mutant cells	MVrDfZRwfG:6aXRCpIF{e2G7	NV;T[YlKOyCmYYnz	MoD0R5l1d3SxeHnjbZR6KGGpYXnud5QhSlKFQUKt[IVncWOrZX70JGNpcW6nc3WgbIFue3SncjDWMWM5KG23dHHueEBk\WyuczDh[pRmeiB\|IHThfZMh[nliV2PUNUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02KG6P	M3L4c\|E5PTB3Mki0
human COR-L279 cell	M3q2UGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYTneZdXUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVwNUSgcm0>	NY[wVFVkW0GQR1XS
human CMK cell	MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NF\WTYdKdmirYnn0bY9vKG:oIHj1cYFvKEOPSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUWuPFMhdk1?	MnzNV2FPT0WU
human MHH-CALL-2 cell	MmTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MkDMTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvQ1HMUE0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi5yNjDuUS=>	MYTTRW5ITVJ?
human BV-173 cell	MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NX;kR3FTUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO\|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N	NVrVbXdSW0GQR1XS
human NCI-H209 cell	MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M2XwfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjF5IH7N	NEPJ[o1USU6JRWK=
human NCI-H460 cell	NHniNXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MUXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok41PSCwTR?=	M3uwdXNCVkeHUh?=
human DU-145 cell	MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4DFWmlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvMUS1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok42OiCwTR?=	M2rHbXNCVkeHUh?=
SW480 colon cancer cell	NF\GepdIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MoCwTY4hfmm2cn:gbY5pcWKrdHnvckBw\iCVV{S4NEBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR\|UxRTdibl2=	MVixPVIxOzR7
human 769-P cell	NV\4d3NJT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NG\hOmRKdmirYnn0bY9vKG:oIHj1cYFvKDd4OT3QJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yOSCwTR?=	MofJV2FPT0WU
human ES1 cell	NVzxOHlCT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXvIc3ZvUW6qaXLpeIlwdiCxZjDoeY1idiCHU{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI6KG6P	NF;UW29USU6JRWK=
human COLO-668 cell	M3\GeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MlG3TY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLU[2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPTVibl2=	MlzzV2FPT0WU
human NKM-1 cell	NVrPSolZT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NYrwSJpkUW6qaXLpeIlwdiCxZjDoeY1idiCQS12tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvQDNibl2=	MnTYV2FPT0WU
human ES3 cell	NXSxWXJsT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M1\zWGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz64PEBvVQ>?	MY\TRW5ITVJ?
human SCC-3 cell	Ml75S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MkLJTY5pcWKrdHnvckBw\iCqdX3hckBUS0NvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUiuOVIhdk1?	NFLxNYVUSU6JRWK=
human SU-DHL-1 cell	NUHnU5hET3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M4PGVGlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZzIH7N	NWfFWlg5W0GQR1XS
human ML-2 cell	NV3IdWdWT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M1;rU2lvcGmkaYTpc44hd2ZiaIXtZY4hVUxvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUiuO\|ghdk1?	M4CyeHNCVkeHUh?=
WiDr colon cancer cell	MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MWnJckB3cXS{bzDpcohq[mm2aX;uJI9nKFerRIKgZ49td25iY3HuZ4VzKGOnbHygcIlv\SxiSVO1NF0yOCCwTR?=	MVuxPVIxOzR7
human SF295 cell	NXi5[YhpT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MUXJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjl3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUGuOFghdk1?	MlXnV2FPT0WU
human EW-7 cell	Mli5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NXzUbG1jUW6qaXLpeIlwdiCxZjDoeY1idiCHVz23JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOTRibl2=	NFfFTYZUSU6JRWK=
human H4 cell	MlLFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NUTKSoEyUW6qaXLpeIlwdiCxZjDoeY1idiCKNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGyMlQ1KG6P	MknTV2FPT0WU
human LB2241-RCC cell	NXTnWo9jT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGHaUWdKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz6xPUBvVQ>?	NUXQdZJzW0GQR1XS
human SR cell	M32y[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NH3sfpJKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuOFYhdk1?	M3vRZnNCVkeHUh?=
human LB1047-RCC cell	NIXiWZFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NW[yNHU5UW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuOkBvVQ>?	M17KdnNCVkeHUh?=
human MCF7 cell	MlLoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NV7wfFl{UW6qaXLpeIlwdiCxZjDoeY1idiCPQ1[3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQSCwTR?=	NVXKSpdmW0GQR1XS
human ESS-1 cell	NHrVT3dIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NInBbW5KdmirYnn0bY9vKG:oIHj1cYFvKEWVUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTJibl2=	MXnTRW5ITVJ?
human NCI-H2122 cell	MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXTncIh2UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz65OkBvVQ>?	M3LkXXNCVkeHUh?=
human 786-0 cell	NEnRbVhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MXPJcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUSuNFEh\|ryP	M4TqfHNCVkeHUh?=
human COLO-205 cell	MoS1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NH;nRpJKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tNlA2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTRwM{Og{txO	M37XRXNCVkeHUh?=
human HAL-01 cell	NU\Qc2lzT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NEDrcm1KdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2Njd\|IN88US=>	MnzTV2FPT0WU
K562 leukemia cells	MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NY\rfot6UW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNiaX6geIhmKHC{ZYPlcoNmKG:oIIDkNkwhUUN3ME2xOU45KG6P	NX\ET4VYOTJ4OUmzPFY>
human MHH-ES-1 cell	NW\WbmxTT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MV7Jcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2HUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvOjZibl2=	MYXTRW5ITVJ?
human NUGC-3 cell	M3rVUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1\Bd2lvcGmkaYTpc44hd2ZiaIXtZY4hVlWJQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvQTVibl2=	MWHTRW5ITVJ?
human RPMI-8402 cell	MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3jm[mlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST24OFAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwMUOgcm0>	NVKxVnBPW0GQR1XS
human ATN-1 cell	MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MmPPTY5pcWKrdHnvckBw\iCqdX3hckBCXE5vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUG3MlM6KG6P	MkHtV2FPT0WU
human NCI-H441 cell	Mm\wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MljITY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSES0NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjZibl2=	NX\jPGxkW0GQR1XS
human LB996-RCC cell	M{\LT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NHrpdZBKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LjDJR\|UxRTF5Lk[4JI5O	MkTTV2FPT0WU
human CAL-148 cell	NUOy[Xh{T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXfBO\|FDUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwOUOgcm0>	M1zrbHNCVkeHUh?=
human CTV-1 cell	NWXkenlHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NIPEeFNKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvPjdibl2=	MnLrV2FPT0WU
human HOP-62 cell	NUPLdII1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MoLSTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNE4zKG6P	MoizV2FPT0WU
human CAKI-1 cell	NHfaTGFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4qxdWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GNST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvOzJibl2=	MnzMV2FPT0WU
human PA-1 cell	MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NIX6fmFKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{42OSCwTR?=	NUjReYhqW0GQR1XS
human HT-144 cell	NF34O\|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M{PkfmlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPzVibl2=	M4\GVXNCVkeHUh?=
human LOUCY cell	Mly1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVS1RZRHUW6qaXLpeIlwdiCxZjDoeY1idiCOT2XDXUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3NjF7IH7N	MWrTRW5ITVJ?
human BPH-1 cell	NXjOSppbT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NYrTfnhXUW6qaXLpeIlwdiCxZjDoeY1idiCEUFitNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI6Njlibl2=	MYTTRW5ITVJ?
human LS-1034 cell	M3;icWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NXjX[lQ6UW6qaXLpeIlwdiCxZjDoeY1idiCOUz2xNFM1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwMU[gcm0>	MkPHV2FPT0WU
human 23132-87 cell	Mk\xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnG5TY5pcWKrdHnvckBw\iCqdX3hckAzOzF\|Mj24O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjV\|IH7N	NYS0NZR7W0GQR1XS
human BB30-HNC cell	M2nN[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NU\6VXV[UW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNyLk[xJI5O	M1foeXNCVkeHUh?=
human CAL-51 cell	MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXW3SJdQUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC56NjDuUS=>	MXHTRW5ITVJ?
human ALL-PO cell	NWDhTG1jT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnH0TY5pcWKrdHnvckBw\iCqdX3hckBCVExvUF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE46QCCwTR?=	MmjtV2FPT0WU
human 5637 cell	MmLIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4frXmlvcGmkaYTpc44hd2ZiaIXtZY4hPTZ\|NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOxMlk{KG6P	NYXHc5BZW0GQR1XS
MCF-7 cell	MUTGeY5kfGmxbjDhd5NigQ>?		NWO3eFZESW62aYT1cY9zKHCxdHXuZ5khd25iaIXtZY4h[nKnYYP0JG1ETi15IHPlcIwhdGmwZYOsJGlEPTB;M{KuNkBvVQ>?	MnvPNVkxPjFyOR?=
human KYSE-150 cell	M1XxVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Ml7JTY5pcWKrdHnvckBw\iCqdX3hckBMYVOHLUG1NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjB7IH7N	NXm5dpUxW0GQR1XS
human RS4-11 cell	M1q5WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NVX1bJNbUW6qaXLpeIlwdiCxZjDoeY1idiCUU{StNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC56NjDuUS=>	NV[yV\|NFW0GQR1XS
human A3-KAW cell	MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		Mk\GTY5pcWKrdHnvckBw\iCqdX3hckBCOy2NQWegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOE46PiCwTR?=	NVv0Z29xW0GQR1XS
human NCI-H719 cell	M2rtUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NEDzUYZKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO\|E6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzVwMUKgcm0>	NHH0RpJUSU6JRWK=
human GI-1 cell	MoDSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MmPXTY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuNVYhdk1?	NFzBU4pUSU6JRWK=
human HEL cell	NXzZUJU4T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MXnJcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN3Lkigcm0>	M13QOXNCVkeHUh?=
human TE-8 cell	MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NGSwVohKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU45PiCwTR?=	NYnncIhOW0GQR1XS
human HT-29 cell	MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MYTJcohq[mm2aX;uJI9nKGi3bXHuJGhVNTJ7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{[uNFIhdk1?	NFnFVWFUSU6JRWK=
human SW1783 cell	MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXTWfYpsUW6qaXLpeIlwdiCxZjDoeY1idiCVV{G3PFMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS5iSVO1NF0{QC53ODDuUS=>	NHjFPJVUSU6JRWK=
human CGTH-W-1 cell	NI\OXnFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NFnvblRKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwIFnDOVA:OzhwN{Sgcm0>	M{\lbnNCVkeHUh?=
human MEL-HO cell	MlnZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MofGTY5pcWKrdHnvckBw\iCqdX3hckBOTUxvSF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU41KG6P	NFPCN2ZUSU6JRWK=
human SW620 cell	NYLEVXo3T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M17sPGlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4MkCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU44QSCwTR?=	NGXVR\|VUSU6JRWK=
Human Caki-1 Renal CellCarcinoma Cell	NVTlRZJnTnWwY4Tpc44h[XO\|YYm=	NWT0VIFzQTZiaB?=	NGPyVHZKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gZYdicW6\|dDDIeY1idiCFYXvpMVEhWmWwYXygR4VtdEOjcnPpco9u[SCFZXzsJGxqdmW\|IDjDSFcxMyliYYSgPVZ1cCCqb4XyMEBq[zVyPUSwJI5O	M{HKS\|E2PzR\|MUe4
human CH1 (ovarian) tumor cell	MnvOR5l1d3SxeHnjxsBie3OjeR?=		M3Hvb3Rp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2gyKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P	NWHvbmxMOTB4OUi0OFQ>
human HT-29 (colon) tumor cell	NHHhR\|REgXSxdH;4bYPDqGG\|c3H5		NWrheW9QXGinIHPvcZBwfW6mIIfhd{BmfmGudXH0[YQh\m:{IITo[UBkgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTCoZ49td25rIIT1cY9zKGOnbHygcIlv\XNuIFnDOVA:PDBibl2=	M4PQVFExPjl6NES0
human A549 cells	MW\DfZRwfG:6aXRCpIF{e2G7	NFTJdYo1QCCq	NG[5NJhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEmFNUC9OFAhdk1?	MU[yOVI2QTVzNR?=
human ME-180 cell	NEO5cm5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MV7Jcohq[mm2aX;uJI9nKGi3bXHuJG1GNTF6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUSwMlEyKG6P	MoTBV2FPT0WU
human CAL-27 cell	NV3ZRndkT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnjhTY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?=	NYHnWVE1W0GQR1XS
human A431 cell	NYezdJBVT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGHKWIhKdmirYnn0bY9vKG:oIHj1cYFvKEF2M{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20N{44PyCwTR?=	NXzufIxoW0GQR1XS
human SW954 cell	M2rjfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NVvDZ\|VGUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjlzIH7N	NFHZbWNUSU6JRWK=
human CAL-39 cell	MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYrhboNQUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytN\|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi52OTDuUS=>	NHe0T3hUSU6JRWK=
human LU-134-A cell	NVXHemtTT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MUPJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF\|ND3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvPzJibl2=	MW\TRW5ITVJ?
human DU-4475 cell	NFniS\|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NV7oZ5c2UW6qaXLpeIlwdiCxZjDoeY1idiCGVT20OFc2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwNEegcm0>	NGfxXWxUSU6JRWK=
P388 cells (P388/S) cells	Mn7rSpVv[3Srb36gZZN{[Xl?		MXjFeoFtfWG2aX;uJI9nKGmwaHnibZRwenliYXP0bZZqfHliYXfhbY5{fCCmcoXnJJNmdnOrdHn2[UBROzh6IHPlcIx{KCiSM{i4M3MqKGOnbHzzMEBKSzVyPUS4JI5O	M1rhblg2PDRzOEO=
human DEL cell	MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MYnJcohq[mm2aX;uJI9nKGi3bXHuJGRGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTR6LkO5JI5O	MYrTRW5ITVJ?
human HGC-27 cell	M2\hc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1XzT2lvcGmkaYTpc44hd2ZiaIXtZY4hUEeFLUK3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvOjlibl2=	MlrvV2FPT0WU
human RH-1 cell	NFXtWYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3GzVmlvcGmkaYTpc44hd2ZiaIXtZY4hWkhvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUS5MlU4KG6P	NGrhUWdUSU6JRWK=
HL-60 cells	NWW3cVdsT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M4XESmlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHige4F{KHO2dXTp[YQhcW5iaIXtZY4heHKxbYnlcI9kgXSrYzDs[ZVs\W2rYzCoTGwuPjBrIHPlcIx{NCCLQ{WwQVUxKG6P	Mk[1PFcxQTFzMR?=
human A2780 (ovarian) tumor cell	MXPDfZRwfG:6aXRCpIF{e2G7		NGq4e\|VVcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIDjveoFzcWGwKTD0eY1weiClZXzsJIxqdmW\|LDDJR\|UxRTVyIH7N	M3r4N\|ExPjl6NES0
human SK-MES-1 cell	NWXuSVROT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NVnmSHRrUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVzLkGyJI5O	NF\sfpFUSU6JRWK=
human MEL-JUSO cell	Mlm3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVrJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2MVWPPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOjVibl2=	NGjFc2VUSU6JRWK=
human VA-ES-BJ cell	M2HHOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MXLJcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVIvOTZibl2=	Ml\TV2FPT0WU
human EW-13 cell	NUWzXooyT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3T2[mlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Nk42OSCwTR?=	MUXTRW5ITVJ?
human Ca-Ski cell	NGjITWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NWHpRZBOUW6qaXLpeIlwdiCxZjDoeY1idiCFYT3Tb4kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Oy55NTDuUS=>	NXvEenc1W0GQR1XS
human LXF-289 cell	NXnaVYZoT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGLCSphKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02PS5\|NzDuUS=>	MWTTRW5ITVJ?
human IM-9 cell	NI\yXJdIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MoCxTY5pcWKrdHnvckBw\iCqdX3hckBKVS17IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NU[uNlIhdk1?	NY\YO21XW0GQR1XS
human HCE-4 cell	NYPFNlBbT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MlfjTY5pcWKrdHnvckBw\iCqdX3hckBJS0VvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUW3Mlk1KG6P	NH\iNmpUSU6JRWK=
human TYK-nu cell	MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NWW1S5E5UW6qaXLpeIlwdiCxZjDoeY1idiCWWVutcpUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QC55MjDuUS=>	NFTWOVdUSU6JRWK=
human NCI-H748 cell	MoW4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MXzJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVkvPTRibl2=	M3Tv[nNCVkeHUh?=
human ABC-1 cell	M{DucGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGFDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NkGuNkBvVQ>?	M4\Ve3NCVkeHUh?=
human CCRF-CEM cell	MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXf4b4tqUW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZzLk[4JI5O	MYHTRW5ITVJ?
human EW-3 cell	MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4HLNWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPU[xMlk2KG6P	Mon1V2FPT0WU
human NCI-H2342 cell	MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M1;YfWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyN\|QzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PjJwNUGgcm0>	NWXMNmExW0GQR1XS
human CNS cancer cells	MW\DfZRwfG:6aXRCpIF{e2G7		M3zUbmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPWyClYX7j[ZIh[2WubIOsJGdKPTB;NkSgcm0>	M{jR[\|EyPDd\|NEG4
human SK-PN-DW cell	M3jJNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M{TnWWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oy55NjDuUS=>	NUO0VGt6W0GQR1XS
human EB2 cell	MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M{C5TmlvcGmkaYTpc44hd2ZiaIXtZY4hTUJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJIlkPTB;NkWuN\|Yhdk1?	MWHTRW5ITVJ?
human HUT78 cells	MoPhVJJwdGmoZYLheIlwdiCjc4PhfS=>	Mn;MOFghcA>?	NFfxc3hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjVWFc5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDy[ZNignW{aX6gdoVlfWO2aX;uJIF{e2G7LDDpZ\|UxRTZ4IH7N	NFXOeowzPjV2MUW4Oy=>
human colon cancer cell line HCT15	Mn7IR5l1d3SxeHnjxsBie3OjeR?=	NYXENXRrPzJiaB?=	MkTXTY4hfmm2cn:gZ5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iY3;sc44h[2GwY3XyJINmdGxibHnu[UBJS1RzNTDh[pRmeiB5MjDodkBw\iCmcoXnJIV5eG:\|dYLlJIRmfGW{bXnu[YQh[nlidHjlJHNTSiCjc4PhfUwhUUN3ME23NEBvVQ>?	MnPONVQ6QDB4N{K=
human HCT8 cells	NH[4XIdEgXSxdH;4bYPDqGG\|c3H5	MmrKO\|IhcA>?	MkLaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyPUizJI5O	M3PqXVE5QDR3NESx
human THP1 cells	MWrDfZRwfG:6aXRCpIF{e2G7	NH72NHk1QCCq	MnvRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBKSzVyPUCuNUDPxE1?	NWGwNmtuOjV{NUm1NVU>
human PC3 cells	MV;Qdo9tcW[ncnH0bY9vKGG\|c3H5	MlfIO\|IhcA>?	M{nrVWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy\|IHHmeIVzKDd{IHjyd{BjgSC2conwZY4h[my3ZTDlfINtfXOrb36gZZN{[XluIFXDOVA:OC5zNDFOwG0>	MVGxPVY4PDlyNR?=

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting. p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane. Beclin 1 / p62 / ATG5; PubMed: 29142609 Oncol Lett (A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; PubMed: 28553347 Neural Regen Res (A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).	24901052 29142609 28553347

In vivo

As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. ^[4]

Protocol

Animal Research:^[4]	- Collapse Animal Models: Rat bladder tumor model Dosages: 400 μM Administration: Intravesical treatment (Only for Reference)

References

[4] Jankun J, et al. Int J Oncol. 2014, 44(1), 147-152.

- Collapse

Solubility (25°C)

In vitro	DMSO	66 mg/mL (197.38 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Mitomycin C SDF

Molecular Weight	334.37
Formula	C₁₅H₁₈N₄O₅
CAS No.	50-07-7
Storage	3 years -20°C powder
Storage	2 years -80°C in solvent
Synonyms	N/A
Smiles	COC12C(COC(N)=O)C3=C(N1CC4NC24)C(=O)C(=C(N)C3=O)C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage

mg/kg

Average weight of animals

Dosing volume per animal

Number of animals

Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)

% DMSO+ % + % Tween 80+ % ddH₂O

Calculate Reset

Calculation results:

Working concentration： mg/ml；

Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH₂O，mix and clarify.

Note：1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2020-05-15)

NCT Number	Recruitment	interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02199327	Completed	Drug: Mitomycin C\|Drug: Interferon Alfa-2b	Conjunctival Intraepithelial Neoplasia\|Corneal Intraepithelial Neoplasia	Coordinación de Investigación en Salud Mexico\|Instituto Mexicano del Seguro Social\|University of Guadalajara	May 2014	Phase 4
NCT02015650	Unknown status	Drug: Cetuximab\|Drug: Mitomycin-C/ 5-Fluorouracil	Head and Neck Neoplasms	Medical University Innsbruck	April 2014	Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Mitomycin C