Mitomycin C

For research use only.

Catalog No.S8146

27 publications

CAS No. 50-07-7

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner.

Selleck's Mitomycin C has been cited by 27 publications

Cell, 2020, 18;S0092-8674(20)30623-1.

PubMed: 32579975 ( click the link to review the publication )

Mol Cell, 2020, 30 pii: S1097-2765(20)30232-X

PubMed: 32359443 ( click the link to review the publication )

Cancer Res, 2020, canres.530.2020

PubMed: 32571799 ( click the link to review the publication )

Cell Death Dis, 2020, 14;11(4):230

PubMed: 32286266 ( click the link to review the publication )

Signal Transduct Target Ther, 2020,

PubMed: 32855386 ( click the link to review the publication )

Sci Rep, 2020, 10(1):931

PubMed: 31969633 ( click the link to review the publication )

Cancer Cell Int, 2020, 19;20:58

PubMed: 32099531 ( click the link to review the publication )

Exp Hematol Oncol, 2020, 9:11

PubMed: 32523801 ( click the link to review the publication )

Front Oncol, 2020, 10:10

PubMed: 32047721 ( click the link to review the publication )

Clin Cancer Res, 2019, 25(6):1957-1969

PubMed: 30482778 ( click the link to review the publication )

Cell Rep, 2019, 27(11):3331-3344

PubMed: 31189115 ( click the link to review the publication )

Protein Cell, 2019, 10.1007/s13238-019-0610-7

PubMed: 30796637 ( click the link to review the publication )

J Cell Physiol, 2019, 10.1002/jcp.28810

PubMed: 31093976 ( click the link to review the publication )

Front Physiol, 2019, 10:24

PubMed: 30745880 ( click the link to review the publication )

Sci China Life Sci, 2019, 10.1007

PubMed: 31872377 ( click the link to review the publication )

Br J Surg, 2019, 10.1002/bjs.11206

PubMed: 31197820 ( click the link to review the publication )

Int J Mol Sci, 2018, 20(1)

PubMed: 30591689 ( click the link to review the publication )

Nanomaterials (Basel), 2018,

PubMed: 29701711 ( click the link to review the publication )

Biomed Pharmacother, 2018, 101:107-114

PubMed: 29477470 ( click the link to review the publication )

Chem Biol Interact, 2018, 296:26-33

PubMed: 30217479 ( click the link to review the publication )

BMC Cancer, 2018, 18(1):426

PubMed: 29661159 ( click the link to review the publication )

Cancer Sci, 2018, 109(11):3450-3460

PubMed: 30191636 ( click the link to review the publication )

Cancer Manag Res, 2018, 10:6791-6802

PubMed: 30588088 ( click the link to review the publication )

Sci Adv, 2018, 4(9):eaar4666

PubMed: 30263952 ( click the link to review the publication )
Oncogene, 2017, 10.1038/onc.2017.6

PubMed: 28218905 ( click the link to review the publication )

Oncol Lett, 2017, 14(6):8035-8041

PubMed: 29344246 ( click the link to review the publication )

Oncotarget, 2017, 8(70):115164-115178

PubMed: 29383150 ( click the link to review the publication )

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner.

Targets

DNA synthesis ^[1]

In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. ^[1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. ^[2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. ^[3]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
human NTERA-S-cl-D1 cell	MmiwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Mmn6TY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj6yNYUuODVizszN	M{fOPXNCVkeHUh?=
human MOLT-4 cell	NFLlUIJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlP1TY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI2\S1yNTFOwG0>	M2H3cHNCVkeHUh?=
human J82 cell	NGi0TlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MkfUTY5pcWKrdHnvckBw\iCqdX3hckBLQDJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkGxPUBvVQ>?	NGPPUGZUSU6JRWK=
human 697 cell	MkW3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NV;jO2xQUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4Phfg+9lCCLQ{WwQVAvOTJ6IH7N	Mon4V2FPT0WU
human KYSE-510 cell	MlzHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NWjK[nl{UW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVUyOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwMUS5JI5O	NYTP[5VHW0GQR1XS
human NCI-H2170 cell	M{\CVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYHtR5Z5UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG1NUBvVQ>?	M2TBUXNCVkeHUh?=
human BE-13 cell	NUHVeXI6T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVjJcohq[mm2aX;uJI9nKGi3bXHuJGJGNTF\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6xOlchdk1?	M3fEdHNCVkeHUh?=
human LC-2-ad cell	NVvmfWpuT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MYXJcohq[mm2aX;uJI9nKGi3bXHuJGxENTJvYXSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1QSCwTR?=	NGTNcWxUSU6JRWK=
human IMR-5 cell	M1rBfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M4f3dGlvcGmkaYTpc44hd2ZiaIXtZY4hUU2ULUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlMxQCCwTR?=	NFPNXJZUSU6JRWK=
human EW-16 cell	Mn7OS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Mlf3TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuN\|Ehdk1?	NIHt[ZdUSU6JRWK=
human MC-IXC cell	NHTPSnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3zjd2lvcGmkaYTpc44hd2ZiaIXtZY4hVUNvSWjDJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43OzhizszN	MVHTRW5ITVJ?
human SW872 cell	M2jjfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MmXhTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuOlc3KM7:TR?=	NWfGb4tbW0GQR1XS
human NCI-H2228 cell	NXziUVk2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHL6SHlKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlIzQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwN{m2JO69VQ>?	MoTnV2FPT0WU
K562 leukemia cells	NFe3T5hIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NXO1SIVGUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNuIFnDOVA:OSCwTR?=	MlPONVI3QTl\|OE[=
human NALM-6 cell	MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MkO1TY5pcWKrdHnvckBw\iCqdX3hckBPSUyPLU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlA4KG6P	MUTTRW5ITVJ?
AA8 cells	NUXMPJZHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=	MUG0JIg>	MUXJcohq[mm2b4L5JIFkfGm4aYT5JI9nKGOxbYDveY5lKG[xcjDBRVgh[2WubIOgeI8hemWmdXPlJINmdGxiZHXud4l1gSCkeTC1NEUhMGW6cH;z[YQhfG9iY3;tdI92dmRiZn;yJFQhcG:3coOp	NXfVZ5hGOjlyOUe0NS=>
human ES4 cell	MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MmLRTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O	M1HMTnNCVkeHUh?=
human KE-37 cell	MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NGrwS2hKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43PCCwTR?=	MVTTRW5ITVJ?
human IST-MEL1 cell	M1j4O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYfGUZR5UW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwNkigcm0>	M3vWWXNCVkeHUh?=
human ES8 cell	MnL1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWPJcohq[mm2aX;uJI9nKGi3bXHuJGVUQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwN{Ggcm0>	NUDGSJRxW0GQR1XS
human MV-4-11 cell	Ml3WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVzJcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc{KG6P	MVnTRW5ITVJ?
human 639-V cell	M{DjWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MnnnTY5pcWKrdHnvckBw\iCqdX3hckA3OzlvVjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGuO\|Yhdk1?	M3XKdXNCVkeHUh?=
human OCI-AML2 cell	NYfPeGVtT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MoDlTY5pcWKrdHnvckBw\iCqdX3hckBQS0lvQV3MNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDlibl2=	NWXi[XRMW0GQR1XS
human SK-LU-1 cell	MnuyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4jJbmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTGWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOjJibl2=	Ml\LV2FPT0WU
human PSN1 cell	NX;BfXduT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		Mn74TY5pcWKrdHnvckBw\iCqdX3hckBRW05zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj61OUBvVQ>?	MkfpV2FPT0WU
human REH cell	NGHlXJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MVnJcohq[mm2aX;uJI9nKGi3bXHuJHJGUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTJwNUWgcm0>	NYrqVGFKW0GQR1XS
human SBC-5 cell	MoPWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NXnVdmJ5UW6qaXLpeIlwdiCxZjDoeY1idiCVQlOtOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPTlibl2=	NHzMO5VUSU6JRWK=
human HT-3 cell	NETlb5BIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M2rtNWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKuPVMhdk1?	MkXZV2FPT0WU
human SIG-M5 cell	NVHJXZRGT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGH2WndKdmirYnn0bY9vKG:oIHj1cYFvKFOLRz3NOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPTJibl2=	MnGwV2FPT0WU
human ES7 cell	MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NFPvOmVKdmirYnn0bY9vKG:oIHj1cYFvKEWVNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOuOlUhdk1?	NGC2VHVUSU6JRWK=
human CHP-212 cell	NXzHXZZ7T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3rjfWlvcGmkaYTpc44hd2ZiaIXtZY4hS0iSLUKxNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOzdibl2=	M4\RUnNCVkeHUh?=
human P12-ICHIKAWA cell	NXHhVWN1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MUfJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTRwN{mgcm0>	NHy5WVFUSU6JRWK=
human HUTU-80 cell	NWrBOmZtT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MmXMTY5pcWKrdHnvckBw\iCqdX3hckBJXVSXLUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45OyCwTR?=	MkjlV2FPT0WU
human P30-OHK cell	MkX4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1noV2lvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDRibl2=	MVvTRW5ITVJ?
human NCI-H1651 cell	NGrL[otIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NGDL[4NKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY2OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTRwOUmgcm0>	NITTcm1USU6JRWK=
Chinese hamster V-C8 mutant cells	M4fCbWN6fG:2b4jpZ:Kh[XO\|YYm=	M33UZlMh\GG7cx?=	NIfIW5lEgXSxdH;4bYNqfHliYXfhbY5{fCCEUlPBNk1l\W[rY3nlcpQhS2irbnXz[UBp[W2\|dHXyJHYuSzhibYX0ZY51KGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDXV3QyKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVibl2=	M2jSWVE5PTB3Mki0
human COR-L279 cell	M1XPU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVLJcohq[mm2aX;uJI9nKGi3bXHuJGNQWi2OMke5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU42PCCwTR?=	Mn2xV2FPT0WU
human CMK cell	MnrtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYLOZ2lrUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlg{KG6P	M4\ubHNCVkeHUh?=
human MHH-CALL-2 cell	NHzFS5NIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NHTWV4RKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3DRWxNNTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkC2JI5O	MkH0V2FPT0WU
human BV-173 cell	MlPXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Ml3mTY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22MlA4KG6P	NEXibHBUSU6JRWK=
human NCI-H209 cell	M3;RbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MULJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok4yPyCwTR?=	NH;4dIFUSU6JRWK=
human NCI-H460 cell	NGr4dnFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MXfJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok41PSCwTR?=	MonTV2FPT0WU
human DU-145 cell	NUjtOJhET3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MULJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTF2NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPU[uOVIhdk1?	M1TEXHNCVkeHUh?=
SW480 colon cancer cell	NHnmcJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		Ml\STY4hfmm2cn:gbY5pcWKrdHnvckBw\iCVV{S4NEBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR\|UxRTdibl2=	NWjPXFQ{OTl{MEO0PS=>
human 769-P cell	M3HtRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MnPOTY5pcWKrdHnvckBw\iCqdX3hckA4PjlvUDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUeuNVEhdk1?	M2jRSnNCVkeHUh?=
human ES1 cell	M4nG[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MWLJcohq[mm2aX;uJI9nKGi3bXHuJGVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTdwMkmgcm0>	M1zLRnNCVkeHUh?=
human COLO-668 cell	M2HHc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NF7uWHhKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tOlY5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py53NTDuUS=>	Mmf2V2FPT0WU
human NKM-1 cell	MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MY\Jcohq[mm2aX;uJI9nKGi3bXHuJG5MVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz64N{BvVQ>?	MUHTRW5ITVJ?
human ES3 cell	M1rsN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M4m5VWlvcGmkaYTpc44hd2ZiaIXtZY4hTVN\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz64PEBvVQ>?	NV3VPGNCW0GQR1XS
human SCC-3 cell	NWLlNnl7T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NInpUFdKdmirYnn0bY9vKG:oIHj1cYFvKFOFQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OiCwTR?=	NHX4[VVUSU6JRWK=
human SU-DHL-1 cell	M1nkN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3zqfWlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZzIH7N	M3O3W3NCVkeHUh?=
human ML-2 cell	NVnLXXBpT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NUnDSpliUW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44QCCwTR?=	NXPKXJlNW0GQR1XS
WiDr colon cancer cell	M1vmWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NIC3fGlKdiC4aYTyc{BqdmirYnn0bY9vKG:oIGfpSJIh[2:ub36gZ4Fv[2W{IHPlcIwhdGmwZTygTWM2OD1zMDDuUS=>	NVP1eolEOTl{MEO0PS=>
human SF295 cell	MnmyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M{fVPGlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z{OUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU41QCCwTR?=	M324XHNCVkeHUh?=
human EW-7 cell	MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYH4Z\|MzUW6qaXLpeIlwdiCxZjDoeY1idiCHVz23JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOTRibl2=	NFmxTY5USU6JRWK=
human H4 cell	M{TOW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MontTY5pcWKrdHnvckBw\iCqdX3hckBJPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF{LkS0JI5O	NXzMXpR7W0GQR1XS
human LB2241-RCC cell	M{PYSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NF7HV4VKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz6xPUBvVQ>?	M1jLdXNCVkeHUh?=
human SR cell	MmPoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NWLGVGNoUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGzMlQ3KG6P	NU\GeVAzW0GQR1XS
human LB1047-RCC cell	M33Pbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NIi1RnVKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz62JI5O	MmjsV2FPT0WU
human MCF7 cell	M{PBZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3nHVWlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGzMlkhdk1?	NGnSeIhUSU6JRWK=
human ESS-1 cell	MkD6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYDsVGxSUW6qaXLpeIlwdiCxZjDoeY1idiCHU2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl{IH7N	NWHTUmlWW0GQR1XS
human NCI-H2122 cell	M33OUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl4IH7N	M4rFR3NCVkeHUh?=
human 786-0 cell	MnHNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWfJcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUSuNFEh\|ryP	NIq3cHhUSU6JRWK=
human COLO-205 cell	M1TDVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MUDJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vMkC1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvOzNizszN	MVnTRW5ITVJ?
human HAL-01 cell	M3;2VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NH:3VlVKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2Njd\|IN88US=>	NVPTVIpnW0GQR1XS
K562 leukemia cells	M1uwPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYjGN2FDUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNiaX6geIhmKHC{ZYPlcoNmKG:oIIDkNkwhUUN3ME2xOU45KG6P	NVTSfWJuOTJ4OUmzPFY>
human MHH-ES-1 cell	MmjzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MlrsTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvRWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE3NjJ4IH7N	M2DIPXNCVkeHUh?=
human NUGC-3 cell	MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NE\yVHRKdmirYnn0bY9vKG:oIHj1cYFvKE6XR1OtN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE3Njl3IH7N	MVPTRW5ITVJ?
human RPMI-8402 cell	MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MXzJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvOESwNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjF\|IH7N	MWXTRW5ITVJ?
human ATN-1 cell	MmToS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWnJcohq[mm2aX;uJI9nKGi3bXHuJGFVVi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUeuN\|khdk1?	MVTTRW5ITVJ?
human NCI-H441 cell	MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MWjJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNESxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPiCwTR?=	NX\SUo54W0GQR1XS
human LB996-RCC cell	M2XqOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NUT0SGF{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT6gTWM2OD1zNz62PEBvVQ>?	MUfTRW5ITVJ?
human CAL-148 cell	NICwSotIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NXGyOFZsUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwOUOgcm0>	NYrOfHlSW0GQR1XS
human CTV-1 cell	MkPTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MlrHTY5pcWKrdHnvckBw\iCqdX3hckBEXFZvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUG4MlY4KG6P	NY\0O41XW0GQR1XS
human HOP-62 cell	NGn0UGVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NIr1fIVKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjJibl2=	M3fFeHNCVkeHUh?=
human CAKI-1 cell	NWPSPFBwT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NF7oWnVKdmirYnn0bY9vKG:oIHj1cYFvKEODS1mtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjN{IH7N	M2qxT3NCVkeHUh?=
human PA-1 cell	NEnuTFVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlPRTY5pcWKrdHnvckBw\iCqdX3hckBRSS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MkOuOVEhdk1?	NYOzco9sW0GQR1XS
human HT-144 cell	NFTGNXVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		Moj1TY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{44PSCwTR?=	MlXuV2FPT0WU
human LOUCY cell	NWXHPWV3T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3XxTmlvcGmkaYTpc44hd2ZiaIXtZY4hVE:XQ2mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOk4yQSCwTR?=	NHflTXhUSU6JRWK=
human BPH-1 cell	MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NILhNplKdmirYnn0bY9vKG:oIHj1cYFvKEKSSD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvQSCwTR?=	NXLhWXV6W0GQR1XS
human LS-1034 cell	M3f4dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MknhTY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMEO0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvOTZibl2=	MXXTRW5ITVJ?
human 23132-87 cell	MkTpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MYXJcohq[mm2aX;uJI9nKGi3bXHuJFI{OTN{LUi3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvPTNibl2=	NYDzUoh{W0GQR1XS
human BB30-HNC cell	MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXzST3o3UW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNyLk[xJI5O	NVvCNo1xW0GQR1XS
human CAL-51 cell	Mnj6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3z1ZWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUWxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvQDZibl2=	M33GcnNCVkeHUh?=
human ALL-PO cell	NYfhXWlWT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVTJcohq[mm2aX;uJI9nKGi3bXHuJGFNVC2STzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOwMlk5KG6P	MVvTRW5ITVJ?
human 5637 cell	MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MlW3TY5pcWKrdHnvckBw\iCqdX3hckA2PjN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{GuPVMhdk1?	NW\EO4d3W0GQR1XS
MCF-7 cell	M1zTTWZ2dmO2aX;uJIF{e2G7		NESyUGpCdnSrdIXtc5IheG:2ZX7jfUBwdiCqdX3hckBjemWjc4SgUWNHNTdiY3XscEBtcW6nczygTWM2OD1\|Mj6yJI5O	NV7QUHpDOTlyNkGwPS=>
human KYSE-150 cell	MnLtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MXvJcohq[mm2aX;uJI9nKGi3bXHuJGt[W0VvMUWwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|QvODlibl2=	NVPCVGd2W0GQR1XS
human RS4-11 cell	MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NUnY[opFUW6qaXLpeIlwdiCxZjDoeY1idiCUU{StNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC56NjDuUS=>	NHTZe29USU6JRWK=
human A3-KAW cell	MlLMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnzYTY5pcWKrdHnvckBw\iCqdX3hckBCOy2NQWegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOE46PiCwTR?=	MlPsV2FPT0WU
human NCI-H719 cell	MlSwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4GwVWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PS5zMjDuUS=>	NVHxUI9{W0GQR1XS
human GI-1 cell	NFTpW4NIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NF7lfI1KdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU4yPiCwTR?=	M4X5dnNCVkeHUh?=
human HEL cell	MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MVHJcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN3Lkigcm0>	NXfB[pRjW0GQR1XS
human TE-8 cell	M3qyXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MkS4TY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuPFYhdk1?	NHvxWZhUSU6JRWK=
human HT-29 cell	MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NV3G[FRkUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2yPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjB{IH7N	MYDTRW5ITVJ?
human SW1783 cell	NVvEdW5MT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NEDZfWJKdmirYnn0bY9vKG:oIHj1cYFvKFOZMUe4N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVM5NjV6IH7N	MYjTRW5ITVJ?
human CGTH-W-1 cell	M2fMVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MXLJcohq[mm2aX;uJI9nKGi3bXHuJGNIXEhvVz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvKEmFNUC9N\|gvPzRibl2=	MlPVV2FPT0WU
human MEL-HO cell	MmnnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NF3ERYZKdmirYnn0bY9vKG:oIHj1cYFvKE2HTD3IU{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjRibl2=	M3qzTXNCVkeHUh?=
human SW620 cell	M{LCNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NI\EZXFKdmirYnn0bY9vKG:oIHj1cYFvKFOZNkKwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|kvPzlibl2=	M4LwcnNCVkeHUh?=
Human Caki-1 Renal CellCarcinoma Cell	NXHaVJVZTnWwY4Tpc44h[XO\|YYm=	MX:5OkBp	M3zKfmlvcGmkaYTvdpkh[2:wY3XueJJifGmxbjDh[4FqdnO2IFj1cYFvKEOja3mtNUBT\W6jbDDD[YxtS2G{Y3nuc41iKEOnbHygUIlv\XNiKFPEO\|AsMSCjdDC5OpRpKGixdYKsJIlkPTB;NECgcm0>	NVnMcIpROTV5NEOxO\|g>
human CH1 (ovarian) tumor cell	NYTEOnJXS3m2b4TvfIlkyqCjc4PhfS=>		MV3UbIUh[2:vcH;1coQhf2G\|IHX2ZYx2[XSnZDDmc5IhfGinIHP5eI91d3irY3n0fUBi\2GrboP0JIh2dWGwIFPINUApd3[jcnnhckkhfHWvb4KgZ4VtdCCuaX7ld{whUUN3ME20NEBvVQ>?	NWjzN3dqOTB4OUi0OFQ>
human HT-29 (colon) tumor cell	NWm0N3dyS3m2b4TvfIlkyqCjc4PhfS=>		NHvZU\|NVcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IDjjc4xwdilidIXtc5Ih[2WubDDsbY5meyxiSVO1NF01OCCwTR?=	M4jaWVExPjl6NES0
human A549 cells	M1jjNmN6fG:2b4jpZ:Kh[XO\|YYm=	M1rFbFQ5KGh?	MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;NECgcm0>	MUOyOVI2QTVzNR?=
human ME-180 cell	M{HucGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NVztZpVjUW6qaXLpeIlwdiCxZjDoeY1idiCPRT2xPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01OC5zMTDuUS=>	MX3TRW5ITVJ?
human CAL-27 cell	MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		Mm\4TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?=	NGe1OXRUSU6JRWK=
human A431 cell	M1HWVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MkG3TY5pcWKrdHnvckBw\iCqdX3hckBCPDNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NEOuO\|chdk1?	MYLTRW5ITVJ?
human SW954 cell	MlnQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MV3Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQTV2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NESuPVEhdk1?	M{DsTXNCVkeHUh?=
human CAL-39 cell	NV7NZ3RbT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NX7uNW5IUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytN\|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi52OTDuUS=>	M4ns[XNCVkeHUh?=
human LU-134-A cell	NEXt[IdIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlP1TY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{StRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ3Njd{IH7N	NVHiRnRZW0GQR1XS
human DU-4475 cell	MlvsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M2LLTmlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvNES3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjR5IH7N	M4jOcXNCVkeHUh?=
P388 cells (P388/S) cells	M3fGUWZ2dmO2aX;uJIF{e2G7		NX;vN4IzTX[jbIXheIlwdiCxZjDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4Sg[JJ2\yC\|ZX7zbZRqfmViUEO4PEBk\WyuczCoVFM5QC:VKTDj[YxteyxiSVO1NF01QCCwTR?=	M4[zcFg2PDRzOEO=
human DEL cell	NXzYdWdHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NFnBcJRKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUS4MlM6KG6P	NFjTSHlUSU6JRWK=
human HGC-27 cell	MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVvVb2RLUW6qaXLpeIlwdiCxZjDoeY1idiCKR1OtNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01QS5{OTDuUS=>	NV3QOZhvW0GQR1XS
human RH-1 cell	MnjyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NF\MbZBKdmirYnn0bY9vKG:oIHj1cYFvKFKKLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PU42PyCwTR?=	M3jDS3NCVkeHUh?=
HL-60 cells	MoHqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Ml74TY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDD3ZZMhe3S3ZHnl[EBqdiCqdX3hckBxem:veXXsc4N6fGmlIHzleYtmdWmlIDjIUE03OCliY3XscJMtKEmFNUC9OVAhdk1?	NVrvdWh6QDdyOUGxNS=>
human A2780 (ovarian) tumor cell	MnWxR5l1d3SxeHnjxsBie3OjeR?=		NXv3W4FNXGinIHPvcZBwfW6mIIfhd{BmfmGudXH0[YQh\m:{IITo[UBkgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCOjd6MDCoc5ZiemmjbjmgeJVud3JiY3XscEBtcW6nczygTWM2OD13MDDuUS=>	NUO0bm1XOTB4OUi0OFQ>
human SK-MES-1 cell	MkLsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVLJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2HUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOTJibl2=	MVfTRW5ITVJ?
human MEL-JUSO cell	MmnPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NW\kfHFLUW6qaXLpeIlwdiCxZjDoeY1idiCPRVytTnVUVyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVzLkK1JI5O	M3z3V3NCVkeHUh?=
human VA-ES-BJ cell	NWnlXpRPT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M1jWN2lvcGmkaYTpc44hd2ZiaIXtZY4hXkFvRWOtRmoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Oi5zNjDuUS=>	NV;3SnRzW0GQR1XS
human EW-13 cell	NXnNcoo{T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHfWfGpKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVIvPTFibl2=	NFzrSpNUSU6JRWK=
human Ca-Ski cell	MmDwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NWXMNmJbUW6qaXLpeIlwdiCxZjDoeY1idiCFYT3Tb4kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Oy55NTDuUS=>	NXu5ZmV5W0GQR1XS
human LXF-289 cell	MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3G4VmlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU2NjN5IH7N	NFzndGRUSU6JRWK=
human IM-9 cell	NVv2RVM3T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NUnQTIt{UW6qaXLpeIlwdiCxZjDoeY1idiCLTT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVYvOjJibl2=	MWTTRW5ITVJ?
human HCE-4 cell	NVjqfI9UT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M2raSWlvcGmkaYTpc44hd2ZiaIXtZY4hUEOHLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21O{46PCCwTR?=	M3X5NnNCVkeHUh?=
human TYK-nu cell	NUX6R41rT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NWjPeIxJUW6qaXLpeIlwdiCxZjDoeY1idiCWWVutcpUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QC55MjDuUS=>	NYjMTWdOW0GQR1XS
human NCI-H748 cell	NX;3VGtZT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3zLbGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3OFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QS53NDDuUS=>	M1:4dHNCVkeHUh?=
human ABC-1 cell	NUXUPG83T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NFTUVphKdmirYnn0bY9vKG:oIHj1cYFvKEGEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvOiCwTR?=	NXH2Tm1LW0GQR1XS
human CCRF-CEM cell	MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGNEWkZvQ1XNJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvPjhibl2=	MVXTRW5ITVJ?
human EW-3 cell	NF3kN\|JIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlnRTY5pcWKrdHnvckBw\iCqdX3hckBGXy1\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NkGuPVUhdk1?	NEC2WFRUSU6JRWK=
human NCI-H2342 cell	MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NH\WNXhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlM1OiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZ{LkWxJI5O	NE\rclNUSU6JRWK=
human CNS cancer cells	MnvxR5l1d3SxeHnjxsBie3OjeR?=		MYHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDUnMh[2GwY3XyJINmdGy\|LDDHTVUxRTZ2IH7N	Ml:2NVE1PzN2MUi=
human SK-PN-DW cell	M1nad2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NXuxXIU3UW6qaXLpeIlwdiCxZjDoeY1idiCVSz3QUk1FXyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZ\|Lke2JI5O	Mkj0V2FPT0WU
human EB2 cell	Mn;3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NGnuT\|JKdmirYnn0bY9vKG:oIHj1cYFvKEWEMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBq[zVyPU[1MlM3KG6P	M3vGNXNCVkeHUh?=
human HUT78 cells	NUH1OZp{WHKxbHnm[ZJifGmxbjDhd5NigQ>?	Ml2wOFghcA>?	M2PHOWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGXUO\|gh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IILld4F7fXKrbjDy[YR2[3Srb36gZZN{[XluIHnjOVA:PjZibl2=	NGjCPWIzPjV2MUW4Oy=>
human colon cancer cell line HCT15	M{T4cGN6fG:2b4jpZ:Kh[XO\|YYm=	M4P0OFczKGh?	MXzJckB3cXS{bzDjfZRwfG:6aXOgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJGhEXDF3IHHmeIVzKDd{IHjyJI9nKGS{dXeg[Zhxd3O3cnWg[IV1\XKvaX7l[EBjgSC2aHWgV3JDKGG\|c3H5MEBKSzVyPUewJI5O	NUPxcHJZOTR7OEC2O\|I>
human HCT8 cells	NGrUUo5EgXSxdH;4bYPDqGG\|c3H5	MoTWO\|IhcA>?	NXnHcmVkS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWODDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwQVg{KG6P	MUmxPFg1PTR2MR?=
human THP1 cells	NXrNcZJ7S3m2b4TvfIlkyqCjc4PhfS=>	MnHEOFghcA>?	M3jXPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHRJWDFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhUUN3ME2wMlEh\|ryP	MXWyOVI2QTVzNR?=
human PC3 cells	NF\BN5lRem:uaX\ldoF1cW:wIHHzd4F6	NHvBSlA4OiCq	MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhfHK7cHHuJIJtfWViZYjjcJV{cW:wIHHzd4F6NCCHQ{WwQVAvOTRizszN	NF;VWWcyQTZ5NEmwOS=>

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting. p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane. Beclin 1 / p62 / ATG5; PubMed: 29142609 Oncol Lett (A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; PubMed: 28553347 Neural Regen Res (A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).	24901052 29142609 28553347

In vivo

As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. ^[4]

Protocol

Animal Research:^[4]	- Collapse Animal Models: Rat bladder tumor model Dosages: 400 μM Administration: Intravesical treatment (Only for Reference)

References

[4] Jankun J, et al. Int J Oncol. 2014, 44(1), 147-152.

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Solubility (25°C)

In vitro	DMSO	66 mg/mL (197.38 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Mitomycin C SDF

Molecular Weight	334.37
Formula	C₁₅H₁₈N₄O₅
CAS No.	50-07-7
Storage	3 years-20°C powder 2 years-80°C in solvent
Synonyms	N/A
Smiles	CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage

mg/kg

Average weight of animals

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Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)

% DMSO+ % + % Tween 80+ % ddH₂O

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Calculation results:

Working concentration： mg/ml；

Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH₂O，mix and clarify.

Note：1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2020-09-01)

NCT Number	Recruitment	interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02199327	Completed	Drug: Mitomycin C\|Drug: Interferon Alfa-2b	Conjunctival Intraepithelial Neoplasia\|Corneal Intraepithelial Neoplasia	Coordinación de Investigación en Salud Mexico\|Instituto Mexicano del Seguro Social\|University of Guadalajara	May 2014	Phase 4
NCT02015650	Terminated	Drug: Cetuximab\|Drug: Mitomycin-C/ 5-Fluorouracil	Head and Neck Neoplasms	Medical University Innsbruck	April 2014	Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Mitomycin C