Mitomycin C

Catalog No.S8146

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Cited by 10 Publications

Protein Cell, 2019, 10.1007/s13238-019-0610-7

PubMed: 30796637 ( click the link to review the publication )

J Cell Physiol, 2019, 10.1002/jcp.28810

PubMed: 31093976 ( click the link to review the publication )

Front Physiol, 2019, 10:24

PubMed: 30745880 ( click the link to review the publication )

Br J Surg, 2019, 10.1002/bjs.11206

PubMed: 31197820 ( click the link to review the publication )

Int J Mol Sci, 2018, 20(1)

PubMed: 30591689 ( click the link to review the publication )

Biomed Pharmacother, 2018, 101:107-114

PubMed: 29477470 ( click the link to review the publication )

BMC Cancer, 2018, 18(1):426

PubMed: 29661159 ( click the link to review the publication )

Cancer Sci, 2018, 109(11):3450-3460

PubMed: 30191636 ( click the link to review the publication )

Oncogene, 2017, 10.1038/onc.2017.6

PubMed: 28218905 ( click the link to review the publication )

Oncol Lett, 2017, 14(6):8035-8041

PubMed: 29344246 ( click the link to review the publication )

1 Customer Review

MTT results of three HCC cell lines at 72 h after indicated treatments. Three independent experiments were carried out.

Cancer Sci, 2018, 109(11):3450-3460. Mitomycin C purchased from Selleck.

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Targets

DNA synthesis ^[1]

In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. ^[1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. ^[2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. ^[3]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
human NTERA-S-cl-D1 cell	MoPUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NFrSbolKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlIy\S1yNTFOwG0>	NFzkRnFUSU6JRWK=
human MOLT-4 cell	NY\lXHM1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NYjMWHczUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{NjJ3ZT2wOUDPxE1?	MXXTRW5ITVJ?
human J82 cell	NGfMZoRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4K3d2lvcGmkaYTpc44hd2ZiaIXtZY4hUjh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6xNVkhdk1?	MnvuV2FPT0WU
human 697 cell	NXezVFY4T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXTNU3RVUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4Phfg+9lCCLQ{WwQVAvOTJ6IH7N	NWPjSWo4W0GQR1XS
human KYSE-510 cell	MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M1\CV2lvcGmkaYTpc44hd2ZiaIXtZY4hU1mVRT21NVAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF2OTDuUS=>	MXPTRW5ITVJ?
human NCI-H2170 cell	MlvMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEfy[YtKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE4OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwMUWxJI5O	MoWxV2FPT0WU
human BE-13 cell	Mk\KS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnroTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuNVY4KG6P	M3fqN3NCVkeHUh?=
human LC-2-ad cell	NHnVVpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MUTJcohq[mm2aX;uJI9nKGi3bXHuJGxENTJvYXSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1QSCwTR?=	M4K1fHNCVkeHUh?=
human IMR-5 cell	NF\rfIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MmG0TY5pcWKrdHnvckBw\iCqdX3hckBKVVJvNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuN\|A5KG6P	MWPTRW5ITVJ?
human EW-16 cell	Mm\JS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVuw[5A6UW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzFibl2=	M1\LZXNCVkeHUh?=
human MC-IXC cell	MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4n3cGlvcGmkaYTpc44hd2ZiaIXtZY4hVUNvSWjDJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43OzhizszN	M1;jc3NCVkeHUh?=
human SW872 cell	M4jTcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M4DKfGlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY4PiEQvF2=	NWC0NFV6W0GQR1XS
human NCI-H2228 cell	MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVL0eG1pUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke5OkDPxE1?	NVvS[YpbW0GQR1XS
K562 leukemia cells	MkHGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NV:5dnpTUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNuIFnDOVA:OSCwTR?=	MYSxNlY6QTN6Nh?=
human NALM-6 cell	NVLxU29mT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVzJcohq[mm2aX;uJI9nKGi3bXHuJG5CVE1vNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGuNFchdk1?	M3zZcHNCVkeHUh?=
AA8 cells	NF;XNXBIem:5dHigbY5pcWKrdHnvckBie3OjeR?=	MoXIOEBp	MWHJcohq[mm2b4L5JIFkfGm4aYT5JI9nKGOxbYDveY5lKG[xcjDBRVgh[2WubIOgeI8hemWmdXPlJINmdGxiZHXud4l1gSCkeTC1NEUhMGW6cH;z[YQhfG9iY3;tdI92dmRiZn;yJFQhcG:3coOp	Mk\6NlkxQTd2MR?=
human ES4 cell	NFe3epVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M{nkU2lvcGmkaYTpc44hd2ZiaIXtZY4hTVN2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT61OkBvVQ>?	Ml\tV2FPT0WU
human KE-37 cell	MoPSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3vhUGlvcGmkaYTpc44hd2ZiaIXtZY4hU0VvM{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlY1KG6P	MlT4V2FPT0WU
human IST-MEL1 cell	NIPKVWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MYXJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43QCCwTR?=	MW\TRW5ITVJ?
human ES8 cell	NVXhbJJLT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MUDJcohq[mm2aX;uJI9nKGi3bXHuJGVUQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwN{Ggcm0>	MXnTRW5ITVJ?
human MV-4-11 cell	Mn\iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MoX3TY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44OyCwTR?=	M4nCdXNCVkeHUh?=
human 639-V cell	NXPtVYM1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MWfJcohq[mm2aX;uJI9nKGi3bXHuJFY{QS2YIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT63OkBvVQ>?	MmfPV2FPT0WU
human OCI-AML2 cell	MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYHsOJNVUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwOEmgcm0>	NV;ofIVsW0GQR1XS
human SK-LU-1 cell	NY\3XYRHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHXtN2pKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzVMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ{IH7N	NV\nPVBbW0GQR1XS
human PSN1 cell	M{XQb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1TMPWlvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKuOVUhdk1?	M3vzXHNCVkeHUh?=
human REH cell	NGK1VpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M{LybGlvcGmkaYTpc44hd2ZiaIXtZY4hWkWKIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj61OUBvVQ>?	Mn:0V2FPT0WU
human SBC-5 cell	NWnVNWN1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MW\Jcohq[mm2aX;uJI9nKGi3bXHuJHNDSy13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj61PUBvVQ>?	M2jpPXNCVkeHUh?=
human HT-3 cell	MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NIjQWo1KdmirYnn0bY9vKG:oIHj1cYFvKEiWLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlk{KG6P	MWDTRW5ITVJ?
human SIG-M5 cell	M{PRbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1L4fWlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42OiCwTR?=	M{L4SXNCVkeHUh?=
human ES7 cell	MnX1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NILv[3pKdmirYnn0bY9vKG:oIHj1cYFvKEWVNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOuOlUhdk1?	NWLme\|BrW0GQR1XS
human CHP-212 cell	Ml3MS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4e1fmlvcGmkaYTpc44hd2ZiaIXtZY4hS0iSLUKxNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOzdibl2=	MmrzV2FPT0WU
human P12-ICHIKAWA cell	M4noNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NIXpXG1KdmirYnn0bY9vKG:oIHj1cYFvKFBzMj3JR2hKU0GZQTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUSuO\|khdk1?	MoK4V2FPT0WU
human HUTU-80 cell	Ml;VS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Moq5TY5pcWKrdHnvckBw\iCqdX3hckBJXVSXLUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45OyCwTR?=	MkDnV2FPT0WU
human P30-OHK cell	Mom2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHHyPWVKdmirYnn0bY9vKG:oIHj1cYFvKFB\|MD3PTGsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njh2IH7N	NFzDN\|RUSU6JRWK=
human NCI-H1651 cell	MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MoD2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2OVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njl7IH7N	NHTDeFhUSU6JRWK=
Chinese hamster V-C8 mutant cells	MYrDfZRwfG:6aXRCpIF{e2G7	NHuyUoQ{KGSjeYO=	NXXlb\|hlS3m2b4TvfIlkcXS7IHHnZYlve3RiQmLDRVIu\GWoaXPp[Y51KEOqaX7ld4UhcGGvc4TldkBXNUN6IH31eIFvfCClZXzsd{Bi\nSncjCzJIRigXNiYomgW3NVOSClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13IH7N	MV[xPFUxPTJ6NB?=
human COR-L279 cell	MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXTURYk6UW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVwNUSgcm0>	MYrTRW5ITVJ?
human CMK cell	NHO0[nFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M1rXS2lvcGmkaYTpc44hd2ZiaIXtZY4hS02NIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NT64N{BvVQ>?	MoToV2FPT0WU
human MHH-CALL-2 cell	NF3RPFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3qyeWlvcGmkaYTpc44hd2ZiaIXtZY4hVUiKLVPBUGwuOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZwME[gcm0>	M1\pcXNCVkeHUh?=
human BV-173 cell	MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NHPuc2VKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvODdibl2=	MmnKV2FPT0WU
human NCI-H209 cell	MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NH3y[VFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlA6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi5zNzDuUS=>	MUHTRW5ITVJ?
human NCI-H460 cell	M3n6T2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NUHU[HdUUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ3OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZwNEWgcm0>	MoLNV2FPT0WU
human DU-145 cell	MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NUX1ToJ{UW6qaXLpeIlwdiCxZjDoeY1idiCGVT2xOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjV{IH7N	M3nVTnNCVkeHUh?=
SW480 colon cancer cell	NGDVOWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MXPJckB3cXS{bzDpcohq[mm2aX;uJI9nKFOZNEiwJINwdG:wIHPhcoNmeiClZXzsJIxqdmVuIFnDOVA:PyCwTR?=	NYG1W3VmOTl{MEO0PS=>
human 769-P cell	MmfrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1jl[WlvcGmkaYTpc44hd2ZiaIXtZY4hPzZ7LWCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlEyKG6P	M1TZW3NCVkeHUh?=
human ES1 cell	MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4Lhd2lvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz6yPUBvVQ>?	NUjpfWxsW0GQR1XS
human COLO-668 cell	MnHIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEfPOplKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tOlY5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py53NTDuUS=>	M330eXNCVkeHUh?=
human NKM-1 cell	M2rQZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3;LfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkuPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23Mlg{KG6P	Mor2V2FPT0WU
human ES3 cell	M13ie2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVzJcohq[mm2aX;uJI9nKGi3bXHuJGVUOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTdwOEigcm0>	M2HFb3NCVkeHUh?=
human SCC-3 cell	MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NFfmcldKdmirYnn0bY9vKG:oIHj1cYFvKFOFQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OiCwTR?=	NUi2TohkW0GQR1XS
human SU-DHL-1 cell	MoPXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3TIV2lvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZzIH7N	M13adXNCVkeHUh?=
human ML-2 cell	NXvyOFBPT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NX;0eJFHUW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44QCCwTR?=	NYG1NIJ3W0GQR1XS
WiDr colon cancer cell	NXG1[pV[T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M2WyTGlvKH[rdILvJIlvcGmkaYTpc44hd2ZiV3nEdkBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR\|UxRTFyIH7N	MXyxPVIxOzR7
human SF295 cell	MnTwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MkTKTY5pcWKrdHnvckBw\iCqdX3hckBUTjJ7NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGxMlQ5KG6P	MYLTRW5ITVJ?
human EW-7 cell	MmezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1XrTGlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGyMlE1KG6P	NYDOTGRHW0GQR1XS
human H4 cell	NIfEUZFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M2L2e2lvcGmkaYTpc44hd2ZiaIXtZY4hUDRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj60OEBvVQ>?	MV\TRW5ITVJ?
human LB2241-RCC cell	Mo[wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NW\5O452UW6qaXLpeIlwdiCxZjDoeY1idiCOQkKyOFEuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuNVkhdk1?	NULjTWlGW0GQR1XS
human SR cell	M2D6dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M2L2TWlvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz60OkBvVQ>?	NUXYRYRTW0GQR1XS
human LB1047-RCC cell	M4PPVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NWT3SGtXUW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuOkBvVQ>?	MW\TRW5ITVJ?
human MCF7 cell	NIS1ZlRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4fwTGlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGzMlkhdk1?	NVH0WYFHW0GQR1XS
human ESS-1 cell	M4DUNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M17KNWlvcGmkaYTpc44hd2ZiaIXtZY4hTVOVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46OiCwTR?=	NYL0VW1yW0GQR1XS
human NCI-H2122 cell	MofHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NUfzXIJTUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz65OkBvVQ>?	NFnMR\|lUSU6JRWK=
human 786-0 cell	M{T0[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYfJcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUSuNFEh\|ryP	MlvsV2FPT0WU
human COLO-205 cell	M3raT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYX2NnBmUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVIxPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF2LkOzJO69VQ>?	MnP0V2FPT0WU
human HAL-01 cell	NGniXIFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NYO4WXNsUW6qaXLpeIlwdiCxZjDoeY1idiCKQVytNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS55MzFOwG0>	NUXLR2YxW0GQR1XS
K562 leukemia cells	NYLHO4Z1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnHoTY4hfmm2cn:gbY5pcWKrdH;yfUBi[3Srdnn0fUBi\2GrboP0JGs2PjJibHX1b4VucWFiY3XscJMhcW5idHjlJJBz\XOnbnPlJI9nKHCmMjygTWM2OD1zNT64JI5O	M3n5NVEzPjl7M{i2
human MHH-ES-1 cell	Ml\xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEPxVI9KdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3FV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTZwMk[gcm0>	M3PyN3NCVkeHUh?=
human NUGC-3 cell	NYfTOYVTT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXzob3h7UW6qaXLpeIlwdiCxZjDoeY1idiCQVVfDMVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPi57NTDuUS=>	MlT1V2FPT0WU
human RPMI-8402 cell	M4jJPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NX2wRm9YUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg1ODJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zNz6xN{BvVQ>?	NHHGNXlUSU6JRWK=
human ATN-1 cell	NFrZdXBIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MoP3TY5pcWKrdHnvckBw\iCqdX3hckBCXE5vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUG3MlM6KG6P	MmXaV2FPT0WU
human NCI-H441 cell	MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M2P1UmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi0OFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy54IH7N	MYLTRW5ITVJ?
human LB996-RCC cell	MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVE4NjZ6IH7N	MVnTRW5ITVJ?
human CAL-148 cell	MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MVvJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC1zNEigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{46OyCwTR?=	NHHOcZJUSU6JRWK=
human CTV-1 cell	NHztfWlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3\jOGlvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE43PyCwTR?=	MlvWV2FPT0WU
human HOP-62 cell	M4PYNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Mk\PTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNE4zKG6P	NIXIS4ZUSU6JRWK=
human CAKI-1 cell	Mkf3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1fXTGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GNST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvOzJibl2=	NInod4VUSU6JRWK=
human PA-1 cell	M4H1XWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MWrJcohq[mm2aX;uJI9nKGi3bXHuJHBCNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz61NUBvVQ>?	MmPKV2FPT0WU
human HT-144 cell	M3rmNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3rQRWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPzVibl2=	NWPCd4dqW0GQR1XS
human LOUCY cell	MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NX7XbVR5UW6qaXLpeIlwdiCxZjDoeY1idiCOT2XDXUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3NjF7IH7N	NWPK[opuW0GQR1XS
human BPH-1 cell	NEf6[oVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGJRUC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MkmuPUBvVQ>?	M2nVeXNCVkeHUh?=
human LS-1034 cell	NGCwT\|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MXXJcohq[mm2aX;uJI9nKGi3bXHuJGxUNTFyM{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE4yPiCwTR?=	MkWyV2FPT0WU
human 23132-87 cell	NXTyTGszT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NX\jPHR7UW6qaXLpeIlwdiCxZjDoeY1idiB{M{GzNk05PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNyLkWzJI5O	NFTDcWdUSU6JRWK=
human BB30-HNC cell	NEXrXoFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		Ml\wTY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjZzIH7N	NH;EeXlUSU6JRWK=
human CAL-51 cell	MlqyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYXEVHU{UW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC56NjDuUS=>	MWDTRW5ITVJ?
human ALL-PO cell	M3S3PWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MnT0TY5pcWKrdHnvckBw\iCqdX3hckBCVExvUF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE46QCCwTR?=	NULHNINIW0GQR1XS
human 5637 cell	NUfKSINYT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NV\hNlR3UW6qaXLpeIlwdiCxZjDoeY1idiB3NkO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|EvQTNibl2=	NFvkT\|ZUSU6JRWK=
MCF-7 cell	MV\GeY5kfGmxbjDhd5NigQ>?		NXXlU5NWSW62aYT1cY9zKHCxdHXuZ5khd25iaIXtZY4h[nKnYYP0JG1ETi15IHPlcIwhdGmwZYOsJGlEPTB;M{KuNkBvVQ>?	MkS3NVkxPjFyOR?=
human KYSE-150 cell	NGLPcWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		Ml:0TY5pcWKrdHnvckBw\iCqdX3hckBMYVOHLUG1NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjB7IH7N	NILuNWpUSU6JRWK=
human RS4-11 cell	NGfnSIFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MnO2TY5pcWKrdHnvckBw\iCqdX3hckBTWzRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOE45PiCwTR?=	NHXPPZRUSU6JRWK=
human A3-KAW cell	NGrjbpNIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGE{NUuDVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUO0Mlk3KG6P	NXPVfmx6W0GQR1XS
human NCI-H719 cell	MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXHNcYtbUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFcyQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN3LkGyJI5O	MXzTRW5ITVJ?
human GI-1 cell	M2DjVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MoXRTY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuNVYhdk1?	NIHObI1USU6JRWK=
human HEL cell	NVPEOnRCT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M4TEPWlvcGmkaYTpc44hd2ZiaIXtZY4hUEWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuPEBvVQ>?	NXfYOFRoW0GQR1XS
human TE-8 cell	NUS3OXp1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MoC2TY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuPFYhdk1?	NWL5[Vh2W0GQR1XS
human HT-29 cell	NGGybYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NEO1d2tKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|YvODJibl2=	MWTTRW5ITVJ?
human SW1783 cell	NWPLbmFST3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NWrIPY5yUW6qaXLpeIlwdiCxZjDoeY1idiCVV{G3PFMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS5iSVO1NF0{QC53ODDuUS=>	MULTRW5ITVJ?
human CGTH-W-1 cell	Ml;aS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NXnwNW86UW6qaXLpeIlwdiCxZjDoeY1idiCFR2TIMXcuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LjDJR\|UxRTN6Lke0JI5O	M4W3enNCVkeHUh?=
human MEL-HO cell	MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYjrblA1UW6qaXLpeIlwdiCxZjDoeY1idiCPRVytTG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{QS52IH7N	M1nscHNCVkeHUh?=
human SW620 cell	M4rmXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Mny4TY5pcWKrdHnvckBw\iCqdX3hckBUXzZ{MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUO5Mlc6KG6P	MV\TRW5ITVJ?
Human Caki-1 Renal CellCarcinoma Cell	NF3qdZhHfW6ldHnvckBie3OjeR?=	MYS5OkBp	NH3pUVhKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gZYdicW6\|dDDIeY1idiCFYXvpMVEhWmWwYXygR4VtdEOjcnPpco9u[SCFZXzsJGxqdmW\|IDjDSFcxMyliYYSgPVZ1cCCqb4XyMEBq[zVyPUSwJI5O	MUmxOVc1OzF5OB?=
human CH1 (ovarian) tumor cell	MnzmR5l1d3SxeHnjxsBie3OjeR?=		M2joWHRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2gyKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P	NV21O45xOTB4OUi0OFQ>
human HT-29 (colon) tumor cell	M{LBRWN6fG:2b4jpZ:Kh[XO\|YYm=		M3z6[nRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliKHPvcI9vMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P	NFXKSlIyODZ7OES0OC=>
human A549 cells	NIL1PJJEgXSxdH;4bYPDqGG\|c3H5	NFmzdoo1QCCq	MXzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;NECgcm0>	MXWyOVI2QTVzNR?=
human ME-180 cell	MnrMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NGPxPXRKdmirYnn0bY9vKG:oIHj1cYFvKE2HLUG4NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQxNjFzIH7N	MnrUV2FPT0WU
human CAL-27 cell	NILTWlFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NULNcJk5UW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01OS5zODDuUS=>	MluwV2FPT0WU
human A431 cell	MnHzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1TqbWlvcGmkaYTpc44hd2ZiaIXtZY4hSTR\|MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUSzMlc4KG6P	NGPoRoZUSU6JRWK=
human SW954 cell	MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVThZWx{UW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjlzIH7N	MUXTRW5ITVJ?
human CAL-39 cell	MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NUHXNG5sUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytN\|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi52OTDuUS=>	MYTTRW5ITVJ?
human LU-134-A cell	M1nFXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NYjsd5JOUW6qaXLpeIlwdiCxZjDoeY1idiCOVT2xN\|QuSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTR4LkeyJI5O	NVW1bIxxW0GQR1XS
human DU-4475 cell	M2nPcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{41PyCwTR?=	NWTJV5p{W0GQR1XS
P388 cells (P388/S) cells	NF;2fZVHfW6ldHnvckBie3OjeR?=		MoLVSZZidHWjdHnvckBw\iCrbnjpZol1d3K7IHHjeIl3cXS7IHHnZYlve3RiZIL1[{B{\W6\|aYTpeoUhWDN6ODDj[YxteyBqUEO4PE9UMSClZXzsd{whUUN3ME20PEBvVQ>?	NVvFV4Z2QDV2NEG4Ny=>
human DEL cell	M1jQXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Mk\6TY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12OD6zPUBvVQ>?	M1PPfXNCVkeHUh?=
human HGC-27 cell	MoO2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NUS2W2hjUW6qaXLpeIlwdiCxZjDoeY1idiCKR1OtNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01QS5{OTDuUS=>	NEnmd\|BUSU6JRWK=
human RH-1 cell	NW\KeoV2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NWrlblJQUW6qaXLpeIlwdiCxZjDoeY1idiCUSD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvPTdibl2=	MVHTRW5ITVJ?
HL-60 cells	MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NHLQe5dKdmirYnn0bY9vKG:oIHPlcIwh\3Kxd4ToJJdieyC\|dIXkbYVlKGmwIHj1cYFvKHC{b335[Yxw[3m2aXOgcIV2c2WvaXOgLGhNNTZyKTDj[YxteyxiSVO1NF02OCCwTR?=	MnzNPFcxQTFzMR?=
human A2780 (ovarian) tumor cell	MlrZR5l1d3SxeHnjxsBie3OjeR?=		NGPsXGZVcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIDjveoFzcWGwKTD0eY1weiClZXzsJIxqdmW\|LDDJR\|UxRTVyIH7N	MV:xNFY6QDR2NB?=
human SK-MES-1 cell	M2nnNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MlfYTY5pcWKrdHnvckBw\iCqdX3hckBUUy2PRWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUyNjF{IH7N	MYrTRW5ITVJ?
human MEL-JUSO cell	NXfJWVVQT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NWXO[41JUW6qaXLpeIlwdiCxZjDoeY1idiCPRVytTnVUVyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVzLkK1JI5O	MVTTRW5ITVJ?
human VA-ES-BJ cell	NHqwS\|dIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4H1ZWlvcGmkaYTpc44hd2ZiaIXtZY4hXkFvRWOtRmoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Oi5zNjDuUS=>	MY\TRW5ITVJ?
human EW-13 cell	MljsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVrJcohq[mm2aX;uJI9nKGi3bXHuJGVYNTF\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NUKuOVEhdk1?	M17JS3NCVkeHUh?=
human Ca-Ski cell	MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M{[2RmlvcGmkaYTpc44hd2ZiaIXtZY4hS2FvU3vpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVMvPzVibl2=	NWrOPWxLW0GQR1XS
human LXF-289 cell	MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MYrJcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21OU4{PyCwTR?=	NWPCW2ZzW0GQR1XS
human IM-9 cell	MoTHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3LubWlvcGmkaYTpc44hd2ZiaIXtZY4hUU1vOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUW2MlIzKG6P	M1P6SXNCVkeHUh?=
human HCE-4 cell	NHrNR2hIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MWXJcohq[mm2aX;uJI9nKGi3bXHuJGhETS12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NUeuPVQhdk1?	NFftXXZUSU6JRWK=
human TYK-nu cell	Mk\0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnfVTY5pcWKrdHnvckBw\iCqdX3hckBVYUtvboWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21PE44OiCwTR?=	MmTiV2FPT0WU
human NCI-H748 cell	Mnm3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NFr0eHFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO\|Q5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PTlwNUSgcm0>	NWLjcI9qW0GQR1XS
human ABC-1 cell	NF;v[5ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NXi3fXJPUW6qaXLpeIlwdiCxZjDoeY1idiCDQlOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYyNjJibl2=	M3rmNXNCVkeHUh?=
human CCRF-CEM cell	MlTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnKyTY5pcWKrdHnvckBw\iCqdX3hckBES1KILVPFUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYyNjZ6IH7N	MWXTRW5ITVJ?
human EW-3 cell	M2CzeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MmLlTY5pcWKrdHnvckBw\iCqdX3hckBGXy1\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NkGuPVUhdk1?	NGPMbVFUSU6JRWK=
human NCI-H2342 cell	NU[3XYNWT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NF36[o1KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlM1OiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZ{LkWxJI5O	MVLTRW5ITVJ?
human CNS cancer cells	M{OwW2N6fG:2b4jpZ:Kh[XO\|YYm=		NGjweXZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEVlNiY3HuZ4VzKGOnbHzzMEBIUTVyPU[0JI5O	M1zre\|EyPDd\|NEG4
human SK-PN-DW cell	NGLDUGxIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3m0[GlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oy55NjDuUS=>	NEL6ZZNUSU6JRWK=
human EB2 cell	NFnxPJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MVrJcohq[mm2aX;uJI9nKGi3bXHuJGVDOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDpZ\|UxRTZ3LkO2JI5O	MWDTRW5ITVJ?
human HUT78 cells	NFfWfIlRem:uaX\ldoF1cW:wIHHzd4F6	MmjrOFghcA>?	NXHaSVVwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWXQ4QCClZXzsd{Bi\nSncjC0PEBpenNiYomgdoV{[Xq3cnnuJJJm\HWldHnvckBie3OjeTygbYM2OD14NjDuUS=>	MnfRNlY2PDF3OEe=
human colon cancer cell line HCT15	M{[3VGN6fG:2b4jpZ:Kh[XO\|YYm=	NHHafoI4OiCq	MoL6TY4hfmm2cn:gZ5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iY3;sc44h[2GwY3XyJINmdGxibHnu[UBJS1RzNTDh[pRmeiB5MjDodkBw\iCmcoXnJIV5eG:\|dYLlJIRmfGW{bXnu[YQh[nlidHjlJHNTSiCjc4PhfUwhUUN3ME23NEBvVQ>?	M1rseVE1QThyNkey
human HCT8 cells	NVj0bXNxS3m2b4TvfIlkyqCjc4PhfS=>	M{fJWFczKGh?	MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3Q5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;OEOgcm0>	M{ixZVE5QDR3NESx
human THP1 cells	MXXDfZRwfG:6aXRCpIF{e2G7	NIDab2s1QCCq	Mo\3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBKSzVyPUCuNUDPxE1?	NYTiNXY5OjV{NUm1NVU>
human PC3 cells	M3;vOHBzd2yrZnXyZZRqd25iYYPzZZk>	MnjRO\|IhcA>?	MmjoRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KHS{eYDhckBjdHWnIHX4Z4x2e2mxbjDhd5NigSxiRVO1NF0xNjF2IN88US=>	NUj1eIxkOTl4N{S5NFU>

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting. p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane. Beclin 1 / p62 / ATG5; PubMed: 29142609 Oncol Lett (A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; PubMed: 28553347 Neural Regen Res (A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).	24901052 29142609 28553347

In vivo

As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. ^[4]

Protocol

Animal Research:^[4]	+ Expand Animal Models: Rat bladder tumor model Formulation: saline Dosages: 400 μM Administration: Intravesical treatment (Only for Reference)

References

[4] Jankun J, et al. Int J Oncol. 2014, 44(1), 147-152.

+ Expand

Solubility (25°C)

In vitro	DMSO	66 mg/mL (197.38 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Mitomycin C SDF

Molecular Weight	334.37
Formula	C₁₅H₁₈N₄O₅
CAS No.	50-07-7
Storage	3 years -20°C powder
Storage	2 years -80°C in solvent
Synonyms	N/A

Bio Calculators

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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The Serial Dilution Calculator Equation

Serial Dilutions
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Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

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Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

NCT Number	Recruitment	interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02199327	Completed	Drug: Mitomycin C\|Drug: Interferon Alfa-2b	Conjunctival Intraepithelial Neoplasia\|Corneal Intraepithelial Neoplasia	Coordinación de Investigación en Salud Mexico\|Instituto Mexicano del Seguro Social\|University of Guadalajara	May 2014	Phase 4
NCT02015650	Unknown status	Drug: Cetuximab\|Drug: Mitomycin-C/ 5-Fluorouracil	Head and Neck Neoplasms	Medical University Innsbruck	April 2014	Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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DNA/RNA Synthesis Signaling Pathway Map

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Mitomycin C

Cited by 10 Publications

1 Customer Review

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Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Dilution Calculator

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products

Choose Your Country or Region

By Signaling Pathways

By product type

Mitomycin C

Cited by 10 Publications

1 Customer Review

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Dilution Calculator

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)