Mitomycin C

For research use only.

Catalog No.S8146

22 publications

Mitomycin C Chemical Structure

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

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Selleck's Mitomycin C has been cited by 22 publications

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.
Targets
DNA synthesis [1]
In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. [1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. [2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human NTERA-S-cl-D1 cell M33uV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF3jcoVKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlIy\S1yNTFOwG0> MkDyV2FPT0WU
human MOLT-4 cell M{X1UWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkjqTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI2\S1yNTFOwG0> NETxemdUSU6JRWK=
human J82 cell MoLzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUjJd3pZUW6qaXLpeIlwdiCxZjDoeY1idiCMOEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlEyQSCwTR?= MnnjV2FPT0WU
human 697 cell M4G3Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVTJcohq[mm2aX;uJI9nKGi3bXHuJFY6PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G778{MJGlEPTB;MD6xNlghdk1? MojGV2FPT0WU
human KYSE-510 cell MkC3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVjJcohq[mm2aX;uJI9nKGi3bXHuJGt[W0VvNUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDlibl2= NUXsfodwW0GQR1XS
human NCI-H2170 cell NWO3dnZCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF74fVdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE4OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMUWxJI5O MV7TRW5ITVJ?
human BE-13 cell NEPCTmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGXVPVJKdmirYnn0bY9vKG:oIHj1cYFvKEKHLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPjdibl2= NUDCdnJ7W0GQR1XS
human LC-2-ad cell Mn;zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml\hTY5pcWKrdHnvckBw\iCqdX3hckBNSy1{LXHkJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDlibl2= MUjTRW5ITVJ?
human IMR-5 cell NWTR[mN1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGlOWi13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6zNFghdk1? NEHyPWZUSU6JRWK=
human EW-16 cell NUDz[nNYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NES1OXJKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{OSCwTR?= M1vXdHNCVkeHUh?=
human MC-IXC cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkHtTY5pcWKrdHnvckBw\iCqdX3hckBOSy2LWFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY{QCEQvF2= NFmzdmFUSU6JRWK=
human SW872 cell NUnOclJrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MofjTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOlc3KM7:TR?= NXrUXo5UW0GQR1XS
human NCI-H2228 cell Mk\jS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXm5blF{UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke5OkDPxE1? NIHPTm5USU6JRWK=
K562 leukemia cells MknsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NITlc3dKdiC4aYTyc{BqdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUzV4MjDs[ZVs\W2rYTDj[YxteyxiSVO1NF0yKG6P MVSxNlY6QTN6Nh?=
human NALM-6 cell NEPJcohIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF3abVBKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvODdibl2= MYPTRW5ITVJ?
AA8 cells MlnZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFLzOFQ1KGh? M{fiOWlvcGmkaYTvdpkh[WO2aY\peJkhd2ZiY3;tdI92dmRiZn;yJGFCQCClZXzsd{B1dyC{ZXT1Z4Uh[2WubDDk[Y5{cXS7IHL5JFUxLSBqZYjwc5Nm\CC2bzDjc41xd3WwZDDmc5IhPCCqb4Xyd{k> M1n1eVI6ODl5NEG=
human ES4 cell NGD0XXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoXJTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O MV7TRW5ITVJ?
human KE-37 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NELncVZKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43PCCwTR?= M334e3NCVkeHUh?=
human IST-MEL1 cell MmnIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYG5PJhCUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwNkigcm0> M3ns[3NCVkeHUh?=
human ES8 cell MkXaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;RfWlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63NUBvVQ>? NVrTc4VwW0GQR1XS
human MV-4-11 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoHkTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44OyCwTR?= NH3hZZpUSU6JRWK=
human 639-V cell M2Hpemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV[wOZhLUW6qaXLpeIlwdiCxZjDoeY1idiB4M{mtWkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPzZibl2= MUPTRW5ITVJ?
human OCI-AML2 cell M4HIVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3z4bmlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh7IH7N NXHkeWQ4W0GQR1XS
human SK-LU-1 cell NYfaU45{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF;kW4ZKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzVMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ{IH7N MXzTRW5ITVJ?
human PSN1 cell M1LGRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFzV[VhKdmirYnn0bY9vKG:oIHj1cYFvKFCVTkGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlU2KG6P MV;TRW5ITVJ?
human REH cell NHzjcphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHv6W4lKdmirYnn0bY9vKG:oIHj1cYFvKFKHSDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOVUhdk1? M2rGOXNCVkeHUh?=
human SBC-5 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI\SW3FKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?= NUjDemJCW0GQR1XS
human HT-3 cell M1HDUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlrOTY5pcWKrdHnvckBw\iCqdX3hckBJXC1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj65N{BvVQ>? M3nneHNCVkeHUh?=
human SIG-M5 cell NXfFbmJlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4HhVmlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42OiCwTR?= M1e0eHNCVkeHUh?=
human ES7 cell NIPLSXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUjJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwNkWgcm0> MUjTRW5ITVJ?
human CHP-212 cell NXrLPIk4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUXJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1{MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlM4KG6P NX74OVBuW0GQR1XS
human P12-ICHIKAWA cell NG\GfmVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYDrUXlwUW6qaXLpeIlwdiCxZjDoeY1idiCSMUKtTWNJUUuDV1GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlc6KG6P M2DINnNCVkeHUh?=
human HUTU-80 cell M4m1S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3HMVmlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDNibl2= M2j0eXNCVkeHUh?=
human P30-OHK cell NVnFWnE1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlL1TY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45PCCwTR?= MnW5V2FPT0WU
human NCI-H1651 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[1NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTlibl2= NGK1NYRUSU6JRWK=
Chinese hamster V-C8 mutant cells MVrDfZRwfG:6aXRCpIF{e2G7 NV;T[YlKOyCmYYnz MoD0R5l1d3SxeHnjbZR6KGGpYXnud5QhSlKFQUKt[IVncWOrZX70JGNpcW6nc3WgbIFue3SncjDWMWM5KG23dHHueEBk\WyuczDh[pRmeiB|IHThfZMh[nliV2PUNUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02KG6P M3L4c|E5PTB3Mki0
human COR-L279 cell M3q2UGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYTneZdXUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSgcm0> NY[wVFVkW0GQR1XS
human CMK cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF\WTYdKdmirYnn0bY9vKG:oIHj1cYFvKEOPSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuPFMhdk1? MnzNV2FPT0WU
human MHH-CALL-2 cell MmTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkDMTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvQ1HMUE0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi5yNjDuUS=> MYTTRW5ITVJ?
human BV-173 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;kR3FTUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N NVrVbXdSW0GQR1XS
human NCI-H209 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2XwfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjF5IH7N NEPJ[o1USU6JRWK=
human NCI-H460 cell NHniNXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok41PSCwTR?= M3uwdXNCVkeHUh?=
human DU-145 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4DFWmlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvMUS1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok42OiCwTR?= M2rHbXNCVkeHUh?=
SW480 colon cancer cell NF\GepdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoCwTY4hfmm2cn:gbY5pcWKrdHnvckBw\iCVV{S4NEBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR|UxRTdibl2= MVixPVIxOzR7
human 769-P cell NV\4d3NJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NG\hOmRKdmirYnn0bY9vKG:oIHj1cYFvKDd4OT3QJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yOSCwTR?= MofJV2FPT0WU
human ES1 cell NVzxOHlCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXvIc3ZvUW6qaXLpeIlwdiCxZjDoeY1idiCHU{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI6KG6P NF;UW29USU6JRWK=
human COLO-668 cell M3\GeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlG3TY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLU[2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPTVibl2= MlzzV2FPT0WU
human NKM-1 cell NVrPSolZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYrwSJpkUW6qaXLpeIlwdiCxZjDoeY1idiCQS12tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvQDNibl2= MnTYV2FPT0WU
human ES3 cell NXSxWXJsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1\zWGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz64PEBvVQ>? MY\TRW5ITVJ?
human SCC-3 cell Ml75S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkLJTY5pcWKrdHnvckBw\iCqdX3hckBUS0NvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuOVIhdk1? NFLxNYVUSU6JRWK=
human SU-DHL-1 cell NUHnU5hET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4PGVGlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZzIH7N NWfFWlg5W0GQR1XS
human ML-2 cell NV3IdWdWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;rU2lvcGmkaYTpc44hd2ZiaIXtZY4hVUxvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuO|ghdk1? M4CyeHNCVkeHUh?=
WiDr colon cancer cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWnJckB3cXS{bzDpcohq[mm2aX;uJI9nKFerRIKgZ49td25iY3HuZ4VzKGOnbHygcIlv\SxiSVO1NF0yOCCwTR?= MVuxPVIxOzR7
human SF295 cell NXi5[YhpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUXJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjl3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOFghdk1? MlXnV2FPT0WU
human EW-7 cell Mli5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXzUbG1jUW6qaXLpeIlwdiCxZjDoeY1idiCHVz23JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOTRibl2= NFfFTYZUSU6JRWK=
human H4 cell MlLFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUTKSoEyUW6qaXLpeIlwdiCxZjDoeY1idiCKNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlQ1KG6P MknTV2FPT0WU
human LB2241-RCC cell NXTnWo9jT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGHaUWdKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz6xPUBvVQ>? NUXQdZJzW0GQR1XS
human SR cell M32y[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH3sfpJKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOFYhdk1? M3vRZnNCVkeHUh?=
human LB1047-RCC cell NIXiWZFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW[yNHU5UW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOkBvVQ>? M17KdnNCVkeHUh?=
human MCF7 cell MlLoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV7wfFl{UW6qaXLpeIlwdiCxZjDoeY1idiCPQ1[3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQSCwTR?= NVXKSpdmW0GQR1XS
human ESS-1 cell NHrVT3dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NInBbW5KdmirYnn0bY9vKG:oIHj1cYFvKEWVUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTJibl2= MXnTRW5ITVJ?
human NCI-H2122 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTncIh2UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz65OkBvVQ>? M3LkXXNCVkeHUh?=
human 786-0 cell NEnRbVhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXPJcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUSuNFEh|ryP M4TqfHNCVkeHUh?=
human COLO-205 cell MoS1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH;nRpJKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tNlA2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTRwM{Og{txO M37XRXNCVkeHUh?=
human HAL-01 cell NU\Qc2lzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEDrcm1KdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2Njd|IN88US=> MnzTV2FPT0WU
K562 leukemia cells MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NY\rfot6UW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNiaX6geIhmKHC{ZYPlcoNmKG:oIIDkNkwhUUN3ME2xOU45KG6P NX\ET4VYOTJ4OUmzPFY>
human MHH-ES-1 cell NW\WbmxTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2HUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvOjZibl2= MYXTRW5ITVJ?
human NUGC-3 cell M3rVUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1\Bd2lvcGmkaYTpc44hd2ZiaIXtZY4hVlWJQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvQTVibl2= MWHTRW5ITVJ?
human RPMI-8402 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3jm[mlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST24OFAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwMUOgcm0> NVKxVnBPW0GQR1XS
human ATN-1 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPPTY5pcWKrdHnvckBw\iCqdX3hckBCXE5vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG3MlM6KG6P MkHtV2FPT0WU
human NCI-H441 cell Mm\wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MljITY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSES0NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjZibl2= NX\jPGxkW0GQR1XS
human LB996-RCC cell M{\LT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHrpdZBKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LjDJR|UxRTF5Lk[4JI5O MkTTV2FPT0WU
human CAL-148 cell NUOy[Xh{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXfBO|FDUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwOUOgcm0> M1zrbHNCVkeHUh?=
human CTV-1 cell NWXkenlHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIPEeFNKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvPjdibl2= MnLrV2FPT0WU
human HOP-62 cell NUPLdII1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoLSTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNE4zKG6P MoizV2FPT0WU
human CAKI-1 cell NHfaTGFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4qxdWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GNST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvOzJibl2= MnzMV2FPT0WU
human PA-1 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIX6fmFKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{42OSCwTR?= NUjReYhqW0GQR1XS
human HT-144 cell NF34O|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{PkfmlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPzVibl2= M4\GVXNCVkeHUh?=
human LOUCY cell Mly1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVS1RZRHUW6qaXLpeIlwdiCxZjDoeY1idiCOT2XDXUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3NjF7IH7N MWrTRW5ITVJ?
human BPH-1 cell NXjOSppbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYrTfnhXUW6qaXLpeIlwdiCxZjDoeY1idiCEUFitNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI6Njlibl2= MYTTRW5ITVJ?
human LS-1034 cell M3;icWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjX[lQ6UW6qaXLpeIlwdiCxZjDoeY1idiCOUz2xNFM1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwMU[gcm0> MkPHV2FPT0WU
human 23132-87 cell Mk\xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnG5TY5pcWKrdHnvckBw\iCqdX3hckAzOzF|Mj24O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjV|IH7N NYS0NZR7W0GQR1XS
human BB30-HNC cell M2nN[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU\6VXV[UW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNyLk[xJI5O M1foeXNCVkeHUh?=
human CAL-51 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXW3SJdQUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC56NjDuUS=> MXHTRW5ITVJ?
human ALL-PO cell NWDhTG1jT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnH0TY5pcWKrdHnvckBw\iCqdX3hckBCVExvUF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE46QCCwTR?= MmjtV2FPT0WU
human 5637 cell MmLIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4frXmlvcGmkaYTpc44hd2ZiaIXtZY4hPTZ|NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOxMlk{KG6P NYXHc5BZW0GQR1XS
MCF-7 cell MUTGeY5kfGmxbjDhd5NigQ>? NWO3eFZESW62aYT1cY9zKHCxdHXuZ5khd25iaIXtZY4h[nKnYYP0JG1ETi15IHPlcIwhdGmwZYOsJGlEPTB;M{KuNkBvVQ>? MnvPNVkxPjFyOR?=
human KYSE-150 cell M1XxVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml7JTY5pcWKrdHnvckBw\iCqdX3hckBMYVOHLUG1NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjB7IH7N NXm5dpUxW0GQR1XS
human RS4-11 cell M1q5WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVX1bJNbUW6qaXLpeIlwdiCxZjDoeY1idiCUU{StNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC56NjDuUS=> NV[yV|NFW0GQR1XS
human A3-KAW cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mk\GTY5pcWKrdHnvckBw\iCqdX3hckBCOy2NQWegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOE46PiCwTR?= NVv0Z29xW0GQR1XS
human NCI-H719 cell M2rtUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEDzUYZKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|E6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzVwMUKgcm0> NHH0RpJUSU6JRWK=
human GI-1 cell MoDSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmPXTY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVYhdk1? NFzBU4pUSU6JRWK=
human HEL cell NXzZUJU4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXnJcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN3Lkigcm0> M13QOXNCVkeHUh?=
human TE-8 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGSwVohKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU45PiCwTR?= NYnncIhOW0GQR1XS
human HT-29 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYTJcohq[mm2aX;uJI9nKGi3bXHuJGhVNTJ7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{[uNFIhdk1? NFnFVWFUSU6JRWK=
human SW1783 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTWfYpsUW6qaXLpeIlwdiCxZjDoeY1idiCVV{G3PFMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS5iSVO1NF0{QC53ODDuUS=> NHjFPJVUSU6JRWK=
human CGTH-W-1 cell NI\OXnFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFnvblRKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwIFnDOVA:OzhwN{Sgcm0> M{\lbnNCVkeHUh?=
human MEL-HO cell MlnZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofGTY5pcWKrdHnvckBw\iCqdX3hckBOTUxvSF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU41KG6P NFPCN2ZUSU6JRWK=
human SW620 cell NYLEVXo3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M17sPGlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4MkCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU44QSCwTR?= NGXVR|VUSU6JRWK=
Human Caki-1 Renal CellCarcinoma Cell NVTlRZJnTnWwY4Tpc44h[XO|YYm= NWT0VIFzQTZiaB?= NGPyVHZKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gZYdicW6|dDDIeY1idiCFYXvpMVEhWmWwYXygR4VtdEOjcnPpco9u[SCFZXzsJGxqdmW|IDjDSFcxMyliYYSgPVZ1cCCqb4XyMEBq[zVyPUSwJI5O M{HKS|E2PzR|MUe4
human CH1 (ovarian) tumor cell MnvOR5l1d3SxeHnjxsBie3OjeR?= M3Hvb3Rp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2gyKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P NWHvbmxMOTB4OUi0OFQ>
human HT-29 (colon) tumor cell NHHhR|REgXSxdH;4bYPDqGG|c3H5 NWrheW9QXGinIHPvcZBwfW6mIIfhd{BmfmGudXH0[YQh\m:{IITo[UBkgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTCoZ49td25rIIT1cY9zKGOnbHygcIlv\XNuIFnDOVA:PDBibl2= M4PQVFExPjl6NES0
human A549 cells MW\DfZRwfG:6aXRCpIF{e2G7 NFTJdYo1QCCq NG[5NJhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEmFNUC9OFAhdk1? MU[yOVI2QTVzNR?=
human ME-180 cell NEO5cm5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJG1GNTF6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSwMlEyKG6P MoTBV2FPT0WU
human CAL-27 cell NV3ZRndkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnjhTY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?= NYHnWVE1W0GQR1XS
human A431 cell NYezdJBVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGHKWIhKdmirYnn0bY9vKG:oIHj1cYFvKEF2M{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20N{44PyCwTR?= NXzufIxoW0GQR1XS
human SW954 cell M2rjfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVvDZ|VGUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjlzIH7N NFHZbWNUSU6JRWK=
human CAL-39 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYrhboNQUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytN|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi52OTDuUS=> NHe0T3hUSU6JRWK=
human LU-134-A cell NVXHemtTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUPJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|ND3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvPzJibl2= MW\TRW5ITVJ?
human DU-4475 cell NFniS|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV7oZ5c2UW6qaXLpeIlwdiCxZjDoeY1idiCGVT20OFc2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwNEegcm0> NGfxXWxUSU6JRWK=
P388 cells (P388/S) cells Mn7rSpVv[3Srb36gZZN{[Xl? MXjFeoFtfWG2aX;uJI9nKGmwaHnibZRwenliYXP0bZZqfHliYXfhbY5{fCCmcoXnJJNmdnOrdHn2[UBROzh6IHPlcIx{KCiSM{i4M3MqKGOnbHzzMEBKSzVyPUS4JI5O M1rhblg2PDRzOEO=
human DEL cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYnJcohq[mm2aX;uJI9nKGi3bXHuJGRGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR6LkO5JI5O MYrTRW5ITVJ?
human HGC-27 cell M2\hc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1XzT2lvcGmkaYTpc44hd2ZiaIXtZY4hUEeFLUK3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvOjlibl2= MlrvV2FPT0WU
human RH-1 cell NFXtWYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3GzVmlvcGmkaYTpc44hd2ZiaIXtZY4hWkhvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS5MlU4KG6P NGrhUWdUSU6JRWK=
HL-60 cells NWW3cVdsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4XESmlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHige4F{KHO2dXTp[YQhcW5iaIXtZY4heHKxbYnlcI9kgXSrYzDs[ZVs\W2rYzCoTGwuPjBrIHPlcIx{NCCLQ{WwQVUxKG6P Mk[1PFcxQTFzMR?=
human A2780 (ovarian) tumor cell MXPDfZRwfG:6aXRCpIF{e2G7 NGq4e|VVcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIDjveoFzcWGwKTD0eY1weiClZXzsJIxqdmW|LDDJR|UxRTVyIH7N M3r4N|ExPjl6NES0
human SK-MES-1 cell NWXuSVROT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVnmSHRrUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVzLkGyJI5O NF\sfpFUSU6JRWK=
human MEL-JUSO cell Mlm3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVrJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2MVWPPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOjVibl2= NGjFc2VUSU6JRWK=
human VA-ES-BJ cell M2HHOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXLJcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVIvOTZibl2= Ml\TV2FPT0WU
human EW-13 cell NUWzXooyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3T2[mlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Nk42OSCwTR?= MUXTRW5ITVJ?
human Ca-Ski cell NGjITWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWHpRZBOUW6qaXLpeIlwdiCxZjDoeY1idiCFYT3Tb4kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Oy55NTDuUS=> NXvEenc1W0GQR1XS
human LXF-289 cell NXnaVYZoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGLCSphKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02PS5|NzDuUS=> MWTTRW5ITVJ?
human IM-9 cell NI\yXJdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoCxTY5pcWKrdHnvckBw\iCqdX3hckBKVS17IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NU[uNlIhdk1? NY\YO21XW0GQR1XS
human HCE-4 cell NYPFNlBbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlfjTY5pcWKrdHnvckBw\iCqdX3hckBJS0VvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUW3Mlk1KG6P NH\iNmpUSU6JRWK=
human TYK-nu cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWW1S5E5UW6qaXLpeIlwdiCxZjDoeY1idiCWWVutcpUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QC55MjDuUS=> NFTWOVdUSU6JRWK=
human NCI-H748 cell MoW4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXzJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVkvPTRibl2= M3Tv[nNCVkeHUh?=
human ABC-1 cell M{DucGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGFDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NkGuNkBvVQ>? M4\Ve3NCVkeHUh?=
human CCRF-CEM cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXf4b4tqUW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZzLk[4JI5O MYHTRW5ITVJ?
human EW-3 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4HLNWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[xMlk2KG6P Mon1V2FPT0WU
human NCI-H2342 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1;YfWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyN|QzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PjJwNUGgcm0> NWXMNmExW0GQR1XS
human CNS cancer cells MW\DfZRwfG:6aXRCpIF{e2G7 M3zUbmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPWyClYX7j[ZIh[2WubIOsJGdKPTB;NkSgcm0> M{jR[|EyPDd|NEG4
human SK-PN-DW cell M3jJNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{TnWWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oy55NjDuUS=> NUO0VGt6W0GQR1XS
human EB2 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{C5TmlvcGmkaYTpc44hd2ZiaIXtZY4hTUJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJIlkPTB;NkWuN|Yhdk1? MWHTRW5ITVJ?
human HUT78 cells MoPhVJJwdGmoZYLheIlwdiCjc4PhfS=> Mn;MOFghcA>? NFfxc3hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjVWFc5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDy[ZNignW{aX6gdoVlfWO2aX;uJIF{e2G7LDDpZ|UxRTZ4IH7N NFXOeowzPjV2MUW4Oy=>
human colon cancer cell line HCT15 Mn7IR5l1d3SxeHnjxsBie3OjeR?= NYXENXRrPzJiaB?= MkTXTY4hfmm2cn:gZ5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iY3;sc44h[2GwY3XyJINmdGxibHnu[UBJS1RzNTDh[pRmeiB5MjDodkBw\iCmcoXnJIV5eG:|dYLlJIRmfGW{bXnu[YQh[nlidHjlJHNTSiCjc4PhfUwhUUN3ME23NEBvVQ>? MnPONVQ6QDB4N{K=
human HCT8 cells NH[4XIdEgXSxdH;4bYPDqGG|c3H5 MmrKO|IhcA>? MkLaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUizJI5O M3PqXVE5QDR3NESx
human THP1 cells MWrDfZRwfG:6aXRCpIF{e2G7 NH72NHk1QCCq MnvRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUCuNUDPxE1? NWGwNmtuOjV{NUm1NVU>
human PC3 cells MV;Qdo9tcW[ncnH0bY9vKGG|c3H5 MlfIO|IhcA>? M{nrVWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDd{IHjyd{BjgSC2conwZY4h[my3ZTDlfINtfXOrb36gZZN{[XluIFXDOVA:OC5zNDFOwG0> MVGxPVY4PDlyNR?=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting.

p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane.

Beclin 1 / p62 / ATG5; 

PubMed: 29142609     


(A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C

GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; 

PubMed: 28553347     


(A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).

24901052 29142609 28553347
In vivo As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. [4]

Protocol

Animal Research:[4]
- Collapse
  • Animal Models: Rat bladder tumor model
  • Dosages: 400 μM
  • Administration: Intravesical treatment
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 66 mg/mL (197.38 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 334.37
Formula

C15H18N4O5

CAS No. 50-07-7
Storage powder
in solvent
Synonyms N/A
Smiles COC12C(COC(N)=O)C3=C(N1CC4NC24)C(=O)C(=C(N)C3=O)C

In vivo Formulation Calculator (Clear solution)

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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02199327 Completed Drug: Mitomycin C|Drug: Interferon Alfa-2b Conjunctival Intraepithelial Neoplasia|Corneal Intraepithelial Neoplasia Coordinación de Investigación en Salud Mexico|Instituto Mexicano del Seguro Social|University of Guadalajara May 2014 Phase 4
NCT02015650 Unknown status Drug: Cetuximab|Drug: Mitomycin-C/ 5-Fluorouracil Head and Neck Neoplasms Medical University Innsbruck April 2014 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID