Mitomycin C

Catalog No.S8146

Mitomycin C Chemical Structure

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

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Cited by 10 Publications

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  • MTT results of three HCC cell lines at 72 h after indicated treatments. Three independent experiments were carried out.

    Cancer Sci, 2018, 109(11):3450-3460. Mitomycin C purchased from Selleck.

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.
Targets
DNA synthesis [1]
In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. [1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. [2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human NTERA-S-cl-D1 cell M2WyNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU[yZoN4UW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4zOWVvMEWg{txO NYCybZdKW0GQR1XS
human MOLT-4 cell MmfVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MU\Jcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuNlVmNTB3IN88US=> NF3CVVZUSU6JRWK=
human J82 cell MlHiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHjNRopKdmirYnn0bY9vKG:oIHj1cYFvKEp6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVE6KG6P NVT2SFZQW0GQR1XS
human 697 cell NY\ad5FqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmrCTY5pcWKrdHnvckBw\iCqdX3hckA3QTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3Ojef-8kEBKSzVyPUCuNVI5KG6P M1uydHNCVkeHUh?=
human KYSE-510 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEnHNopKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtOVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zNEmgcm0> NWjGTJlOW0GQR1XS
human NCI-H2170 cell M{XEWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXO0V4UxUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG1NUBvVQ>? Mk\pV2FPT0WU
human BE-13 cell MoKxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVf6OmZCUW6qaXLpeIlwdiCxZjDoeY1idiCERT2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTZ5IH7N MULTRW5ITVJ?
human LC-2-ad cell NWLwRXB[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlvwTY5pcWKrdHnvckBw\iCqdX3hckBNSy1{LXHkJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDlibl2= MmTzV2FPT0WU
human IMR-5 cell MkL3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4HxXmlvcGmkaYTpc44hd2ZiaIXtZY4hUU2ULUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlMxQCCwTR?= MkPqV2FPT0WU
human EW-16 cell M3LQWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\MTHpWUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzFibl2= NEDZPVBUSU6JRWK=
human MC-IXC cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDMeGxKUW6qaXLpeIlwdiCxZjDoeY1idiCPQz3JXGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ|ODFOwG0> NYrTfWl5W0GQR1XS
human SW872 cell NYjlbnFlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD62O|Yh|ryP M4n0NHNCVkeHUh?=
human NCI-H2228 cell MoLmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYDaO4c5UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke5OkDPxE1? MlO5V2FPT0WU
K562 leukemia cells NXrtNos4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV;BR5pqUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNuIFnDOVA:OSCwTR?= MVOxNlY6QTN6Nh?=
human NALM-6 cell M3TYXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5CVE1vNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFchdk1? MkfUV2FPT0WU
AA8 cells NEPS[nhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmnxOEBp NG\PclNKdmirYnn0c5J6KGGldHn2bZR6KG:oIHPvcZBwfW6mIH\vdkBCSThiY3XscJMhfG9icnXkeYNmKGOnbHyg[IVve2m2eTDifUA2OCViKHX4dI9{\WRidH:gZ49ueG:3bnSg[o9zKDRiaH;1dpMq MnzBNlkxQTd2MR?=
human ES4 cell MmjXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml3WTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O NEO3c|JUSU6JRWK=
human KE-37 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXnJcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT62OEBvVQ>? NVLTeIR6W0GQR1XS
human IST-MEL1 cell MoDCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUHJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43QCCwTR?= NIPYVYRUSU6JRWK=
human ES8 cell M2HHc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3:3bmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63NUBvVQ>? MVXTRW5ITVJ?
human MV-4-11 cell MmHLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXjJcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc{KG6P MoHxV2FPT0WU
human 639-V cell Mn;WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGnEfotKdmirYnn0bY9vKG:oIHj1cYFvKDZ|OT3WJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44PiCwTR?= Mn;sV2FPT0WU
human OCI-AML2 cell M3nYXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2XoSGlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh7IH7N NFrERYJUSU6JRWK=
human SK-LU-1 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHvkXotKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzVMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ{IH7N NYDiXpBUW0GQR1XS
human PSN1 cell NF:1eZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnLYTY5pcWKrdHnvckBw\iCqdX3hckBRW05zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj61OUBvVQ>? MmDXV2FPT0WU
human REH cell Mn7sS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnXNTY5pcWKrdHnvckBw\iCqdX3hckBTTUhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkW1JI5O M13VUnNCVkeHUh?=
human SBC-5 cell MoHDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIrsRWlKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?= MXfTRW5ITVJ?
human HT-3 cell NYP5NWU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnqyTY5pcWKrdHnvckBw\iCqdX3hckBJXC1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj65N{BvVQ>? NUfQbo5[W0GQR1XS
human SIG-M5 cell Mn3RS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2eyRWlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42OiCwTR?= Mne5V2FPT0WU
human ES7 cell M4XVcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwNkWgcm0> NYHoSIFXW0GQR1XS
human CHP-212 cell M17jN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVjJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1{MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlM4KG6P M1TzXXNCVkeHUh?=
human P12-ICHIKAWA cell NFG4fIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXTJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwN{mgcm0> MUnTRW5ITVJ?
human HUTU-80 cell NHrjZW1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1vkbGlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDNibl2= M{npR3NCVkeHUh?=
human P30-OHK cell MkPrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1W2V2lvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDRibl2= NE[2fnVUSU6JRWK=
human NCI-H1651 cell M4jjWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnrqTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2OVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njl7IH7N NF7pXnBUSU6JRWK=
Chinese hamster V-C8 mutant cells NYnXRogxS3m2b4TvfIlkyqCjc4PhfS=> M4qxUlMh\GG7cx?= M4DwPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEKUQ1GyMYRm\mmlaXXueEBEcGmwZYPlJIhidXO2ZYKgWk1EQCCvdYThcpQh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IGfTWFEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PSCwTR?= NYDqdYN5OTh3MEWyPFQ>
human COR-L279 cell MkTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXfY[HNvUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSgcm0> NFrVZZRUSU6JRWK=
human CMK cell MmDqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYG2eWJGUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlg{KG6P MnPUV2FPT0WU
human MHH-CALL-2 cell NI\MN3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnzoTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvQ1HMUE0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi5yNjDuUS=> NYXWO4FoW0GQR1XS
human BV-173 cell M4XUUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX[4dFJCUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N NVG2VpBGW0GQR1XS
human NCI-H209 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MojRTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOTdibl2= NIHKUIhUSU6JRWK=
human NCI-H460 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX3yfG1EUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ3OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZwNEWgcm0> NXrzUYl6W0GQR1XS
human DU-145 cell NIX0PVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV75PIlbUW6qaXLpeIlwdiCxZjDoeY1idiCGVT2xOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjV{IH7N M1q1THNCVkeHUh?=
SW480 colon cancer cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGPlPJBKdiC4aYTyc{BqdmirYnn0bY9vKG:oIGPXOFgxKGOxbH;uJINidmOncjDj[YxtKGyrbnWsJGlEPTB;NzDuUS=> M3HTOVE6OjB|NEm=
human 769-P cell M3fLSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGrvOnJKdmirYnn0bY9vKG:oIHj1cYFvKDd4OT3QJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yOSCwTR?= M4PFcXNCVkeHUh?=
human ES1 cell NEDlUYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorxTY5pcWKrdHnvckBw\iCqdX3hckBGWzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkK5JI5O NUT6TWJ2W0GQR1XS
human COLO-668 cell MnKyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHnOcYJKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tOlY5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py53NTDuUS=> NHrkPZVUSU6JRWK=
human NKM-1 cell M{C3O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYLJcohq[mm2aX;uJI9nKGi3bXHuJG5MVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz64N{BvVQ>? M{PKb3NCVkeHUh?=
human ES3 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3PQfGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz64PEBvVQ>? NE\zc3NUSU6JRWK=
human SCC-3 cell NX3ibnpQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGjsWYdKdmirYnn0bY9vKG:oIHj1cYFvKFOFQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OiCwTR?= M4rhT3NCVkeHUh?=
human SU-DHL-1 cell M135PGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYTJcohq[mm2aX;uJI9nKGi3bXHuJHNWNUSKTD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE43OSCwTR?= NIjod3BUSU6JRWK=
human ML-2 cell MlTzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1NNTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD16Lke4JI5O MUjTRW5ITVJ?
WiDr colon cancer cell NEjCTYJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVPJckB3cXS{bzDpcohq[mm2aX;uJI9nKFerRIKgZ49td25iY3HuZ4VzKGOnbHygcIlv\SxiSVO1NF0yOCCwTR?= M4naZlE6OjB|NEm=
human SF295 cell NWTOUm9QT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV65XXVYUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK5OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjR6IH7N M2jJbnNCVkeHUh?=
human EW-7 cell NXXROlBUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1XBNWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlE1KG6P NH\jfFFUSU6JRWK=
human H4 cell NGDve3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DvfWlvcGmkaYTpc44hd2ZiaIXtZY4hUDRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj60OEBvVQ>? Mo[3V2FPT0WU
human LB2241-RCC cell MmH2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33t[GlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF|LkG5JI5O MkfTV2FPT0WU
human SR cell M1foemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\wSoNOUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlQ3KG6P NH24[ZFUSU6JRWK=
human LB1047-RCC cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFHSWolKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz62JI5O NV;wbm1WW0GQR1XS
human MCF7 cell MnnxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFu0[G5KdmirYnn0bY9vKG:oIHj1cYFvKE2FRkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46KG6P NWPteINbW0GQR1XS
human ESS-1 cell NV3LVVN1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXjyfWF5UW6qaXLpeIlwdiCxZjDoeY1idiCHU2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl{IH7N Mn;jV2FPT0WU
human NCI-H2122 cell M2DR[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnnJTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NjDuUS=> NI\uVGdUSU6JRWK=
human 786-0 cell NIfkbJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NITN[opKdmirYnn0bY9vKG:oIHj1cYFvKDd6Nj2wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvODFizszN MkfMV2FPT0WU
human COLO-205 cell NEDUWFZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3LNRmlvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz2yNFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC5|MzFOwG0> M3j5b3NCVkeHUh?=
human HAL-01 cell MoHMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWHJcohq[mm2aX;uJI9nKGi3bXHuJGhCVC1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG1Mlc{KM7:TR?= MWXTRW5ITVJ?
K562 leukemia cells NF\NbWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXXLS4tmUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNiaX6geIhmKHC{ZYPlcoNmKG:oIIDkNkwhUUN3ME2xOU45KG6P MUCxNlY6QTN6Nh?=
human MHH-ES-1 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2HUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvOjZibl2= MmL5V2FPT0WU
human NUGC-3 cell M2LCWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJG5WT0NvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG2Mlk2KG6P MXjTRW5ITVJ?
human RPMI-8402 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlKxTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLUi0NFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy5zMzDuUS=> MYjTRW5ITVJ?
human ATN-1 cell Mn[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NY\TbZkyUW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjN7IH7N MoPEV2FPT0WU
human NCI-H441 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVfDcFVQUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ1OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF5Lk[gcm0> NE[zOmhUSU6JRWK=
human LB996-RCC cell NInOeHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MULJcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVE4NjZ6IH7N NFm4NoVUSU6JRWK=
human CAL-148 cell M1rGemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LpTGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4Njl|IH7N M2fUXnNCVkeHUh?=
human CTV-1 cell NFfRTllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3nMO2lvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE43PyCwTR?= NF62bXJUSU6JRWK=
human HOP-62 cell NE[yZ4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4TtOWlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvOiCwTR?= M1vwPXNCVkeHUh?=
human CAKI-1 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEfVOZRKdmirYnn0bY9vKG:oIHj1cYFvKEODS1mtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjN{IH7N M2L0eXNCVkeHUh?=
human PA-1 cell Mmi0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHPnWHZKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{42OSCwTR?= NVnhNohwW0GQR1XS
human HT-144 cell NFLWeXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUPJcohq[mm2aX;uJI9nKGi3bXHuJGhVNTF2NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlc2KG6P NEHib4JUSU6JRWK=
human LOUCY cell MofVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEjzTlJKdmirYnn0bY9vKG:oIHj1cYFvKEyRVVPZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlYvOTlibl2= NX22ZVJUW0GQR1XS
human BPH-1 cell M3qxUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4Lpd2lvcGmkaYTpc44hd2ZiaIXtZY4hSlCKLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU46KG6P MXPTRW5ITVJ?
human LS-1034 cell NYC4NXI2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MofOTY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMEO0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvOTZibl2= NWj5O|diW0GQR1XS
human 23132-87 cell NXHCfGo{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7ReIRKdmirYnn0bY9vKG:oIHj1cYFvKDJ|MUOyMVg4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwNUOgcm0> MWrTRW5ITVJ?
human BB30-HNC cell NXztNYN3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Moq2TY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjZzIH7N NIPDb4ZUSU6JRWK=
human CAL-51 cell M1r4VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXvJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC13MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOwMlg3KG6P MoThV2FPT0WU
human ALL-PO cell NGLDcWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{\OPWlvcGmkaYTpc44hd2ZiaIXtZY4hSUyOLWDPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvQThibl2= MmC3V2FPT0WU
human 5637 cell NEnDdnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHrWUopKdmirYnn0bY9vKG:oIHj1cYFvKDV4M{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNU46OyCwTR?= M3ftO3NCVkeHUh?=
MCF-7 cell NWnvXpRITnWwY4Tpc44h[XO|YYm= NWqyTYVwSW62aYT1cY9zKHCxdHXuZ5khd25iaIXtZY4h[nKnYYP0JG1ETi15IHPlcIwhdGmwZYOsJGlEPTB;M{KuNkBvVQ>? NFTIdmIyQTB4MUC5
human KYSE-150 cell NYXBWHhpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPPT5FKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtNVUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwMEmgcm0> MV3TRW5ITVJ?
human RS4-11 cell MnPYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHrPSpJKdmirYnn0bY9vKG:oIHj1cYFvKFKVND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1Njh4IH7N NV3tTGJ2W0GQR1XS
human A3-KAW cell NFPSZlRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3TCTGlvcGmkaYTpc44hd2ZiaIXtZY4hSTNvS1HXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|QvQTZibl2= M1PQdHNCVkeHUh?=
human NCI-H719 cell NYHYUYVLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlL0TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEexPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjF{IH7N NVvLd|VHW0GQR1XS
human GI-1 cell M4raemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3TKd2lvcGmkaYTpc44hd2ZiaIXtZY4hT0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO1MlE3KG6P M2TZS3NCVkeHUh?=
human HEL cell Ml;iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN3Lkigcm0> Mmr6V2FPT0WU
human TE-8 cell MonVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|NT64OkBvVQ>? M{Cyd3NCVkeHUh?=
human HT-29 cell M3vRPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVPxbGU2UW6qaXLpeIlwdiCxZjDoeY1idiCKVD2yPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjB{IH7N M1\n[nNCVkeHUh?=
human SW1783 cell M2T2cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHPTbXBKdmirYnn0bY9vKG:oIHj1cYFvKFOZMUe4N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVM5NjV6IH7N M4L1ZXNCVkeHUh?=
human CGTH-W-1 cell NGXRS5JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlPRTY5pcWKrdHnvckBw\iCqdX3hckBET1SKLWetNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVM5Njd2IH7N MUnTRW5ITVJ?
human MEL-HO cell NEH5dGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYXDTFFVUW6qaXLpeIlwdiCxZjDoeY1idiCPRVytTG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{QS52IH7N MkTjV2FPT0WU
human SW620 cell NF;LRlFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NILSfm9KdmirYnn0bY9vKG:oIHj1cYFvKFOZNkKwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvPzlibl2= M2X6Z3NCVkeHUh?=
Human Caki-1 Renal CellCarcinoma Cell M2fMU2Z2dmO2aX;uJIF{e2G7 M1LBR|k3KGh? MlXkTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiSIXtZY4hS2GtaT2xJHJmdmGuIFPlcIxE[XKlaX7vcYEhS2WubDDMbY5meyBqQ1S3NEsqKGG2IEm2eIghcG:3cjygbYM2OD12MDDuUS=> MV:xOVc1OzF5OB?=
human CH1 (ovarian) tumor cell M{LWUWN6fG:2b4jpZ:Kh[XO|YYm= MoDDWIhmKGOxbYDveY5lKHejczDleoFtfWG2ZXSg[o9zKHSqZTDjfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDTFEhMG:4YYLpZY4qKHS3bX;yJINmdGxibHnu[ZMtKEmFNUC9OFAhdk1? NYLlNYpXOTB4OUi0OFQ>
human HT-29 (colon) tumor cell M1T2NmN6fG:2b4jpZ:Kh[XO|YYm= M1H5SXRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliKHPvcI9vMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P M3PZWVExPjl6NES0
human A549 cells MnHrR5l1d3SxeHnjxsBie3OjeR?= M13DcVQ5KGh? MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;NECgcm0> NIDlT3YzPTJ3OUWxOS=>
human ME-180 cell NH;BdoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4TLcGlvcGmkaYTpc44hd2ZiaIXtZY4hVUVvMUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFAvOTFibl2= MWDTRW5ITVJ?
human CAL-27 cell M1uxfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn25TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?= Mn\yV2FPT0WU
human A431 cell M4jtO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkjVTY5pcWKrdHnvckBw\iCqdX3hckBCPDNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEOuO|chdk1? M2m2PXNCVkeHUh?=
human SW954 cell NVnSNGtiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnL1TY5pcWKrdHnvckBw\iCqdX3hckBUXzl3NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS0MlkyKG6P M33CR3NCVkeHUh?=
human CAL-39 cell M17oZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXzJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC1|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS2MlQ6KG6P MUDTRW5ITVJ?
human LU-134-A cell NUTMU2x6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrGXlRKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwN{Kgcm0> M4TudHNCVkeHUh?=
human DU-4475 cell NXfDWHloT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYLJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{41PyCwTR?= M2rZPXNCVkeHUh?=
P388 cells (P388/S) cells NVf3XVZnTnWwY4Tpc44h[XO|YYm= NGP2OZpGfmGudXH0bY9vKG:oIHnubIljcXSxcomgZYN1cX[rdImgZYdicW6|dDDkdpVoKHOnboPpeIl3\SCSM{i4JINmdGy|IDjQN|g5N1NrIHPlcIx{NCCLQ{WwQVQ5KG6P MYm4OVQ1OTh|
human DEL cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXnNZ5doUW6qaXLpeIlwdiCxZjDoeY1idiCGRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PE4{QSCwTR?= MVjTRW5ITVJ?
human HGC-27 cell NI\tdlJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4jLXmlvcGmkaYTpc44hd2ZiaIXtZY4hUEeFLUK3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvOjlibl2= MnvNV2FPT0WU
human RH-1 cell MnjES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmP6TY5pcWKrdHnvckBw\iCqdX3hckBTUC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEmuOVchdk1? NYj2VYo3W0GQR1XS
HL-60 cells MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnPnTY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDD3ZZMhe3S3ZHnl[EBqdiCqdX3hckBxem:veXXsc4N6fGmlIHzleYtmdWmlIDjIUE03OCliY3XscJMtKEmFNUC9OVAhdk1? NVL6WFE{QDdyOUGxNS=>
human A2780 (ovarian) tumor cell MWDDfZRwfG:6aXRCpIF{e2G7 NHvFU45VcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIDjveoFzcWGwKTD0eY1weiClZXzsJIxqdmW|LDDJR|UxRTVyIH7N MUWxNFY6QDR2NB?=
human SK-MES-1 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWrMR4s5UW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVzLkGyJI5O NFLjcXdUSU6JRWK=
human MEL-JUSO cell MmjXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVzJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2MVWPPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOjVibl2= NGLMZ4FUSU6JRWK=
human VA-ES-BJ cell NHnhNZlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFHMbFNKdmirYnn0bY9vKG:oIHj1cYFvKF[DLVXTMWJLKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PTJwMU[gcm0> M17WPHNCVkeHUh?=
human EW-13 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlK0TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWyMlUyKG6P Mnz1V2FPT0WU
human Ca-Ski cell NYXGW5BIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3Hab2lvcGmkaYTpc44hd2ZiaIXtZY4hS2FvU3vpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVMvPzVibl2= NGX5[odUSU6JRWK=
human LXF-289 cell NUnnRWZnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4PLd2lvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU2NjN5IH7N M3X6WXNCVkeHUh?=
human IM-9 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYH0U5NbUW6qaXLpeIlwdiCxZjDoeY1idiCLTT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVYvOjJibl2= M{\tWnNCVkeHUh?=
human HCE-4 cell NV3rSGFZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmLGTY5pcWKrdHnvckBw\iCqdX3hckBJS0VvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUW3Mlk1KG6P MXjTRW5ITVJ?
human TYK-nu cell MlK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4DXVmlvcGmkaYTpc44hd2ZiaIXtZY4hXFmNLX71JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVgvPzJibl2= MlzMV2FPT0WU
human NCI-H748 cell Ml3RS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1;rSGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3OFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QS53NDDuUS=> M3L6ZnNCVkeHUh?=
human ABC-1 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEj1O3BKdmirYnn0bY9vKG:oIHj1cYFvKEGEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvOiCwTR?= MUXTRW5ITVJ?
human CCRF-CEM cell M2jxe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3vacmlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03OS54ODDuUS=> NWPUe3V4W0GQR1XS
human EW-3 cell NVmxNVBQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XseWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[xMlk2KG6P M3npS3NCVkeHUh?=
human NCI-H2342 cell MlvOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoDpTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKzOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oi53MTDuUS=> Ml[yV2FPT0WU
human CNS cancer cells NGS1R41EgXSxdH;4bYPDqGG|c3H5 NGH3Tm1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEVlNiY3HuZ4VzKGOnbHzzMEBIUTVyPU[0JI5O MX2xNVQ4OzRzOB?=
human SK-PN-DW cell MlXJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV;Idm9rUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3QUk1FXyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZ|Lke2JI5O MY\TRW5ITVJ?
human EB2 cell NGrFUmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVqx[mFTUW6qaXLpeIlwdiCxZjDoeY1idiCHQkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhcWN3ME22OU4{PiCwTR?= MUPTRW5ITVJ?
human HUT78 cells MomwVJJwdGmoZYLheIlwdiCjc4PhfS=> NHnseo01QCCq NF7lc5hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjVWFc5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDy[ZNignW{aX6gdoVlfWO2aX;uJIF{e2G7LDDpZ|UxRTZ4IH7N NWfBV4hmOjZ3NEG1PFc>
human colon cancer cell line HCT15 NY\lSmd3S3m2b4TvfIlkyqCjc4PhfS=> M1[2cFczKGh? MYfJckB3cXS{bzDjfZRwfG:6aXOgZYN1cX[rdImgZYdicW6|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJGhEXDF3IHHmeIVzKDd{IHjyJI9nKGS{dXeg[Zhxd3O3cnWg[IV1\XKvaX7l[EBjgSC2aHWgV3JDKGG|c3H5MEBKSzVyPUewJI5O NWriW|ZjOTR7OEC2O|I>
human HCT8 cells NFXPb3lEgXSxdH;4bYPDqGG|c3H5 NVzyV|REPzJiaB?= Mn;nR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUizJI5O M4m1W|E5QDR3NESx
human THP1 cells MnH3R5l1d3SxeHnjxsBie3OjeR?= NGG5[2k1QCCq MmrVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUCuNUDPxE1? NFmwZY4zPTJ3OUWxOS=>
human PC3 cells M3HZVXBzd2yrZnXyZZRqd25iYYPzZZk> NILHXYI4OiCq NXn2SZNRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IITyfZBidiCkbIXlJIV5[2y3c3nvckBie3OjeTygSWM2OD1yLkG0JO69VQ>? NEnNelEyQTZ5NEmwOS=>

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting.

p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane.

Beclin 1 / p62 / ATG5; 

PubMed: 29142609     


(A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C

GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; 

PubMed: 28553347     


(A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).

24901052 29142609 28553347
In vivo As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. [4]

Protocol

Animal Research:[4]
+ Expand
  • Animal Models: Rat bladder tumor model
  • Formulation: saline
  • Dosages: 400 μM
  • Administration: Intravesical treatment
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 66 mg/mL (197.38 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 334.37
Formula

C15H18N4O5

CAS No. 50-07-7
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03875911 Recruiting Glaucoma Open-Angle Primary|Glaucoma|Open Angle Glaucoma|Glaucoma Open-Angle University of California Los Angeles March 30 2019 Phase 4
NCT03875911 Recruiting Glaucoma Open-Angle Primary|Glaucoma|Open Angle Glaucoma|Glaucoma Open-Angle University of California Los Angeles March 30 2019 Phase 4
NCT03658304 Recruiting Urothelial Carcinoma University of Florida December 5 2018 Phase 2
NCT03658304 Recruiting Urothelial Carcinoma University of Florida December 5 2018 Phase 2
NCT03664869 Not yet recruiting Bladder Cancer Turku University Hospital|Finnbladder October 26 2018 Phase 3
NCT03664869 Not yet recruiting Bladder Cancer Turku University Hospital|Finnbladder October 26 2018 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID