Mitomycin C

Catalog No.S8146

Mitomycin C Chemical Structure

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

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Cited by 16 Publications

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  • MTT results of three HCC cell lines at 72 h after indicated treatments. Three independent experiments were carried out.

    Cancer Sci, 2018, 109(11):3450-3460. Mitomycin C purchased from Selleck.

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.
Targets
DNA synthesis [1]
In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. [1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. [2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human NTERA-S-cl-D1 cell NWPYPHM2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVfJcohq[mm2aX;uJI9nKGi3bXHuJG5VTVKDLWOtZ4wuTDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkKx[U0xPSEQvF2= NUGxZWFUW0GQR1XS
human MOLT-4 cell Mn\aS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1jPRWlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPWVvMEWg{txO MWXTRW5ITVJ?
human J82 cell M4Hae2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1W5b2lvcGmkaYTpc44hd2ZiaIXtZY4hUjh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xNVkhdk1? NGjuUIdUSU6JRWK=
human 697 cell NELrdHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYSy[VhHUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4Phfg+9lCCLQ{WwQVAvOTJ6IH7N M33vZXNCVkeHUh?=
human KYSE-510 cell NXvsWGhHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXW4dI56UW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVUyOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMUS5JI5O NFzq[W1USU6JRWK=
human NCI-H2170 cell M{TXV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVrqO|ZCUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG1NUBvVQ>? MVnTRW5ITVJ?
human BE-13 cell M3zXcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJGJGNTF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xOlchdk1? M3znS3NCVkeHUh?=
human LC-2-ad cell MkL4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVLkOYZjUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2yMYFlKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5{NEmgcm0> Ml\HV2FPT0WU
human IMR-5 cell M1frRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXTJcohq[mm2aX;uJI9nKGi3bXHuJGlOWi13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6zNFghdk1? MUHTRW5ITVJ?
human EW-16 cell Mn\nS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnO4TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|Ehdk1? NYTvXm5oW0GQR1XS
human MC-IXC cell M3y4Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmCyTY5pcWKrdHnvckBw\iCqdX3hckBOSy2LWFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY{QCEQvF2= M2fH[3NCVkeHUh?=
human SW872 cell NUPWUHFLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnnJTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOlc3KM7:TR?= MV\TRW5ITVJ?
human NCI-H2228 cell NXG5V3RyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrTUGhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlIzQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwN{m2JO69VQ>? MX;TRW5ITVJ?
K562 leukemia cells NYTZcXZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIHHfWZKdiC4aYTyc{BqdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUzV4MjDs[ZVs\W2rYTDj[YxteyxiSVO1NF0yKG6P MkLhNVI3QTl|OE[=
human NALM-6 cell MorZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3\NSGlvcGmkaYTpc44hd2ZiaIXtZY4hVkGOTT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xPyCwTR?= Mn7EV2FPT0WU
AA8 cells NFWwfINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYftbJJ5PCCq MnTUTY5pcWKrdH;yfUBi[3Srdnn0fUBw\iClb33wc5Vv\CCob4KgRWE5KGOnbHzzJJRwKHKnZIXj[UBk\WyuIHTlcpNqfHliYomgOVAmKCineIDvd4VlKHSxIHPvcZBwfW6mIH\vdkA1KGixdYLzLS=> NVP2NYNNOjlyOUe0NS=>
human ES4 cell MlnIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVvnNJBnUW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlU3KG6P Mn3wV2FPT0WU
human KE-37 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT62OEBvVQ>? NIHaPGhUSU6JRWK=
human IST-MEL1 cell NYq3Z|B7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWPJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43QCCwTR?= NXTGNIxqW0GQR1XS
human ES8 cell M4r6bmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NITXcnBKdmirYnn0bY9vKG:oIHj1cYFvKEWVODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuO|Ehdk1? NX75U4FiW0GQR1XS
human MV-4-11 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVjJcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc{KG6P MmDNV2FPT0WU
human 639-V cell NYXGTmFbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFjibHdKdmirYnn0bY9vKG:oIHj1cYFvKDZ|OT3WJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44PiCwTR?= M3r0b3NCVkeHUh?=
human OCI-AML2 cell NXnRXppvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX24[IFqUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwOEmgcm0> NUnjPWJ7W0GQR1XS
human SK-LU-1 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4TnXWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTGWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOjJibl2= NFPUVZZUSU6JRWK=
human PSN1 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3\uOmlvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOVUhdk1? MlXnV2FPT0WU
human REH cell NVLsVWtHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJHJGUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwNUWgcm0> MXPTRW5ITVJ?
human SBC-5 cell MmrMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEjPd5JKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?= NUXTWXRpW0GQR1XS
human HT-3 cell NV3MSnRUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrTc3BKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlk{KG6P NUSye2tYW0GQR1XS
human SIG-M5 cell NGG3Z49Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlXJTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlUzKG6P M4LQb3NCVkeHUh?=
human ES7 cell NYjwb5B2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwNkWgcm0> NIDZdFBUSU6JRWK=
human CHP-212 cell NHj1TWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVO4bGtQUW6qaXLpeIlwdiCxZjDoeY1idiCFSGCtNlEzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5|NzDuUS=> M4jYbnNCVkeHUh?=
human P12-ICHIKAWA cell NF\DWmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWDJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwN{mgcm0> MUTTRW5ITVJ?
human HUTU-80 cell NIraeXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEjyVG1KdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njh|IH7N M4jGS3NCVkeHUh?=
human P30-OHK cell NV7zPW5RT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn3FTY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45PCCwTR?= MmW2V2FPT0WU
human NCI-H1651 cell NFu2fY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYHZcmxHUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE3PTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Lkm5JI5O M37IRnNCVkeHUh?=
Chinese hamster V-C8 mutant cells M1vlTGN6fG:2b4jpZ:Kh[XO|YYm= NVvqO4xzOyCmYYnz M4WyWmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEKUQ1GyMYRm\mmlaXXueEBEcGmwZYPlJIhidXO2ZYKgWk1EQCCvdYThcpQh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IGfTWFEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PSCwTR?= NIfJdGUyQDVyNUK4OC=>
human COR-L279 cell MlruS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYexRppIUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSgcm0> M3\BfnNCVkeHUh?=
human CMK cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkWyTY5pcWKrdHnvckBw\iCqdX3hckBEVUtiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkizJI5O NX[3boMxW0GQR1XS
human MHH-CALL-2 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX\2eYQ5UW6qaXLpeIlwdiCxZjDoeY1idiCPSFitR2FNVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6wOkBvVQ>? NHKwOoNUSU6JRWK=
human BV-173 cell M2rGT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXT3TWZTUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N NEXBfXpUSU6JRWK=
human NCI-H209 cell Mm\TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoD2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOTdibl2= NHPJRo9USU6JRWK=
human NCI-H460 cell NWfiTXdLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIDTXnJKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOFYxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi52NTDuUS=> M17uN3NCVkeHUh?=
human DU-145 cell MmTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTF2NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uOVIhdk1? M1PTeXNCVkeHUh?=
SW480 colon cancer cell MnPSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUO2S5hLUW5idnn0do8hcW6qaXLpeIlwdiCxZjDTW|Q5OCClb3zvckBk[W6lZYKgZ4VtdCCuaX7lMEBKSzVyPUegcm0> Ml75NVkzODN2OR?=
human 769-P cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlfSTY5pcWKrdHnvckBw\iCqdX3hckA4PjlvUDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNVEhdk1? MnSzV2FPT0WU
human ES1 cell NUTZXYZbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3X3WGlvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz6yPUBvVQ>? MWPTRW5ITVJ?
human COLO-668 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnYfoQ3UW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVY3QCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwNUWgcm0> NELCfXpUSU6JRWK=
human NKM-1 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3\Ue2lvcGmkaYTpc44hd2ZiaIXtZY4hVkuPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23Mlg{KG6P NYK3e5d[W0GQR1XS
human ES3 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoPhTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15Lki4JI5O MXfTRW5ITVJ?
human SCC-3 cell M4\iXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX7Ue5ZMUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1OtN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPTJibl2= MWjTRW5ITVJ?
human SU-DHL-1 cell M{PocWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml3MTY5pcWKrdHnvckBw\iCqdX3hckBUXS2GSFytNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPjFibl2= NX;wR|MzW0GQR1XS
human ML-2 cell M2jQdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3zqc2lvcGmkaYTpc44hd2ZiaIXtZY4hVUxvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuO|ghdk1? M1:2NXNCVkeHUh?=
WiDr colon cancer cell NGOzNYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2CxemlvKH[rdILvJIlvcGmkaYTpc44hd2ZiV3nEdkBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR|UxRTFyIH7N MVKxPVIxOzR7
human SF295 cell NYjxRWVIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVGz[Y5GUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK5OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjR6IH7N MWrTRW5ITVJ?
human EW-7 cell M17jXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{m0NGlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlE1KG6P M4nINXNCVkeHUh?=
human H4 cell M4TjeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn;ETY5pcWKrdHnvckBw\iCqdX3hckBJPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{LkS0JI5O NIL2[5BUSU6JRWK=
human LB2241-RCC cell NW\xOVB[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3XGeWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF|LkG5JI5O M4HLcXNCVkeHUh?=
human SR cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH\1emZKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOFYhdk1? M2jw[XNCVkeHUh?=
human LB1047-RCC cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmDYTY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwNjDuUS=> NHTJfohUSU6JRWK=
human MCF7 cell M2T3NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2HwcGlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlkhdk1? NFXNW4hUSU6JRWK=
human ESS-1 cell NHzhRmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGVUWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuPVIhdk1? NEjseFdUSU6JRWK=
human NCI-H2122 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm\2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NjDuUS=> NHzyXHZUSU6JRWK=
human 786-0 cell M1X6cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2nwNmlvcGmkaYTpc44hd2ZiaIXtZY4hPzh4LUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE4xOSEQvF2= MXrTRW5ITVJ?
human COLO-205 cell MkTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVfabYVGUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVIxPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF2LkOzJO69VQ>? NXPPN4Z1W0GQR1XS
human HAL-01 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHu4UmxKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2Njd|IN88US=> MWfTRW5ITVJ?
K562 leukemia cells MljiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX3JckB3cXS{bzDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4SgT|U3OiCuZYXr[Y1q[SClZXzsd{BqdiC2aHWgdJJme2WwY3Wgc4YheGR{LDDJR|UxRTF3Lkigcm0> NI\OSIYyOjZ7OUO4Oi=>
human MHH-ES-1 cell M{fkRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NY\KSY9PUW6qaXLpeIlwdiCxZjDoeY1idiCPSFitSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF4LkK2JI5O NVftXmF4W0GQR1XS
human NUGC-3 cell MlzlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1f3WWlvcGmkaYTpc44hd2ZiaIXtZY4hVlWJQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvQTVibl2= NWXBTmRpW0GQR1XS
human RPMI-8402 cell NH:1d5RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWjJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvOESwNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjF|IH7N M1[4e3NCVkeHUh?=
human ATN-1 cell NHO2OZNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFPUdWVKdmirYnn0bY9vKG:oIHj1cYFvKEGWTj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOzlibl2= MVLTRW5ITVJ?
human NCI-H441 cell Mk\PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEL3cmdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOFQyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwNjDuUS=> Mo\wV2FPT0WU
human LB996-RCC cell NHzGRYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmW4TY5pcWKrdHnvckBw\iCqdX3hckBNSjl7Nj3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS5iSVO1NF0yPy54ODDuUS=> Mm\UV2FPT0WU
human CAL-148 cell NYrlNmNzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVrpbXhRUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwOUOgcm0> M1Sx[3NCVkeHUh?=
human CTV-1 cell M{mySGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWDJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUiuOlchdk1? M3PsS3NCVkeHUh?=
human HOP-62 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4rsZmlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvOiCwTR?= MVrTRW5ITVJ?
human CAKI-1 cell NXLLVnVzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVnJcohq[mm2aX;uJI9nKGi3bXHuJGNCU0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlMzKG6P Moe3V2FPT0WU
human PA-1 cell M4LPdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYPJcohq[mm2aX;uJI9nKGi3bXHuJHBCNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz61NUBvVQ>? NH7xOWhUSU6JRWK=
human HT-144 cell M{DOfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4PFVmlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPzVibl2= NEXHNWFUSU6JRWK=
human LOUCY cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUH6dIZvUW6qaXLpeIlwdiCxZjDoeY1idiCOT2XDXUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3NjF7IH7N NXXBW4J3W0GQR1XS
human BPH-1 cell Ml7BS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3XabWlvcGmkaYTpc44hd2ZiaIXtZY4hSlCKLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU46KG6P MXrTRW5ITVJ?
human LS-1034 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoD5TY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMEO0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvOTZibl2= NVm4fnJkW0GQR1XS
human 23132-87 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFm1fJJKdmirYnn0bY9vKG:oIHj1cYFvKDJ|MUOyMVg4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwNUOgcm0> NXT5fmlsW0GQR1XS
human BB30-HNC cell M2\aUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1zLdmlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC54MTDuUS=> Mm\4V2FPT0WU
human CAL-51 cell M3vqb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWL0eItSUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC56NjDuUS=> M1fMeXNCVkeHUh?=
human ALL-PO cell MoXnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHjBSIlKdmirYnn0bY9vKG:oIHj1cYFvKEGOTD3QU{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjl6IH7N NYn5Rnh3W0GQR1XS
human 5637 cell NIHnUmxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M37GVGlvcGmkaYTpc44hd2ZiaIXtZY4hPTZ|NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOxMlk{KG6P Mn7EV2FPT0WU
MCF-7 cell NH;IdWVHfW6ldHnvckBie3OjeR?= MkHoRY51cXS3bX;yJJBwfGWwY4mgc44hcHWvYX6gZpJm[XO2IF3DSk04KGOnbHygcIlv\XNuIFnDOVA:OzJwMjDuUS=> MWWxPVA3OTB7
human KYSE-150 cell NHG5ZmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUfzO3FKUW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVE2OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN2LkC5JI5O MnjRV2FPT0WU
human RS4-11 cell M122Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHPVSpBKdmirYnn0bY9vKG:oIHj1cYFvKFKVND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1Njh4IH7N MnTmV2FPT0WU
human A3-KAW cell Mkn4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV3uOotkUW6qaXLpeIlwdiCxZjDoeY1idiCDMz3LRXch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC57NjDuUS=> Mn\4V2FPT0WU
human NCI-H719 cell NGTK[nJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWPkZ|dpUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFcyQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN3LkGyJI5O NEKxbodUSU6JRWK=
human GI-1 cell MnLZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn\6TY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVYhdk1? MYPTRW5ITVJ?
human HEL cell Mk[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NES5fYtKdmirYnn0bY9vKG:oIHj1cYFvKEiHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO1Mlghdk1? MV3TRW5ITVJ?
human TE-8 cell NF;kOJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorFTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuPFYhdk1? NF;yO3JUSU6JRWK=
human HT-29 cell M1r1S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEjTUmpKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvODJibl2= NIezVWxUSU6JRWK=
human SW1783 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rjb2lvcGmkaYTpc44hd2ZiaIXtZY4hW1dzN{izJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvKEmFNUC9N|gvPThibl2= M3noXnNCVkeHUh?=
human CGTH-W-1 cell NGP4dYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH20V5hKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwIFnDOVA:OzhwN{Sgcm0> MojlV2FPT0WU
human MEL-HO cell M4D2TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYLJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2KTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlQhdk1? MlWxV2FPT0WU
human SW620 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVWzXXByUW6qaXLpeIlwdiCxZjDoeY1idiCVV{[yNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6Njd7IH7N MYrTRW5ITVJ?
Human Caki-1 Renal CellCarcinoma Cell NIfwOYxHfW6ldHnvckBie3OjeR?= M3LFSFk3KGh? Mkf3TY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiSIXtZY4hS2GtaT2xJHJmdmGuIFPlcIxE[XKlaX7vcYEhS2WubDDMbY5meyBqQ1S3NEsqKGG2IEm2eIghcG:3cjygbYM2OD12MDDuUS=> MX:xOVc1OzF5OB?=
human CH1 (ovarian) tumor cell NYf4RWFsS3m2b4TvfIlkyqCjc4PhfS=> MYfUbIUh[2:vcH;1coQhf2G|IHX2ZYx2[XSnZDDmc5IhfGinIHP5eI91d3irY3n0fUBi\2GrboP0JIh2dWGwIFPINUApd3[jcnnhckkhfHWvb4KgZ4VtdCCuaX7ld{whUUN3ME20NEBvVQ>? MX2xNFY6QDR2NB?=
human HT-29 (colon) tumor cell NXWyNZdHS3m2b4TvfIlkyqCjc4PhfS=> M2rUOnRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliKHPvcI9vMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P MkPKNVA3QTh2NES=
human A549 cells NWXQPIlmS3m2b4TvfIlkyqCjc4PhfS=> NIPpfVQ1QCCq MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;NECgcm0> M3fkUlI2OjV7NUG1
human ME-180 cell MoLQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWjJcohq[mm2aX;uJI9nKGi3bXHuJG1GNTF6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSwMlEyKG6P NVjZXHdDW0GQR1XS
human CAL-27 cell MlvLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnrDTY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?= NGj0VJZUSU6JRWK=
human A431 cell NYrnWHRFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3TPUmlvcGmkaYTpc44hd2ZiaIXtZY4hSTR|MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSzMlc4KG6P NULCVVQ5W0GQR1XS
human SW954 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVTMNnZqUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjlzIH7N NYLvVnB{W0GQR1XS
human CAL-39 cell M{TWPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkDITY5pcWKrdHnvckBw\iCqdX3hckBESUxvM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok41QSCwTR?= M2\tcHNCVkeHUh?=
human LU-134-A cell NFPQd4xIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NET4UJdKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwN{Kgcm0> MnfKV2FPT0WU
human DU-4475 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3f1VGlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvNES3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjR5IH7N NX\ydWNuW0GQR1XS
P388 cells (P388/S) cells NGnJV3ZHfW6ldHnvckBie3OjeR?= NUTVeFFSTX[jbIXheIlwdiCxZjDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4Sg[JJ2\yC|ZX7zbZRqfmViUEO4PEBk\WyuczCoVFM5QC:VKTDj[YxteyxiSVO1NF01QCCwTR?= MXS4OVQ1OTh|
human DEL cell M3LaR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NI\LS5BKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS4MlM6KG6P NGDue3BUSU6JRWK=
human HGC-27 cell M1TVV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoC3TY5pcWKrdHnvckBw\iCqdX3hckBJT0NvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PU4zQSCwTR?= M4DoWnNCVkeHUh?=
human RH-1 cell MmK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYny[|E6UW6qaXLpeIlwdiCxZjDoeY1idiCUSD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvPTdibl2= MXjTRW5ITVJ?
HL-60 cells MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYnJcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIIfhd{B{fHWmaXXkJIlvKGi3bXHuJJBzd227ZXzvZ5l1cWNibHX1b4VucWNiKFjMMVYxMSClZXzsd{whUUN3ME21NEBvVQ>? M4Gwc|g4ODlzMUG=
human A2780 (ovarian) tumor cell NUL5bZE{S3m2b4TvfIlkyqCjc4PhfS=> MX;UbIUh[2:vcH;1coQhf2G|IHX2ZYx2[XSnZDDmc5IhfGinIHP5eI91d3irY3n0fUBi\2GrboP0JIh2dWGwIFGyO|gxKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVUxKG6P M1PJS|ExPjl6NES0
human SK-MES-1 cell NYPQbZVxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmHqTY5pcWKrdHnvckBw\iCqdX3hckBUUy2PRWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUyNjF{IH7N NW\hWI5KW0GQR1XS
human MEL-JUSO cell NFHW[Y9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3z0SGlvcGmkaYTpc44hd2ZiaIXtZY4hVUWOLVrVV28h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02OS5{NTDuUS=> M3[yRXNCVkeHUh?=
human VA-ES-BJ cell M3PpdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUO2T4JGUW6qaXLpeIlwdiCxZjDoeY1idiCYQT3FV{1DUiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTV{LkG2JI5O NF3EN2JUSU6JRWK=
human EW-13 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmjTTY5pcWKrdHnvckBw\iCqdX3hckBGXy1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWyMlUyKG6P Mlz1V2FPT0WU
human Ca-Ski cell NH3POYRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFTINXZKdmirYnn0bY9vKG:oIHj1cYFvKEOjLWPrbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU{Njd3IH7N NHnEU5ZUSU6JRWK=
human LXF-289 cell NWHReXBYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkfGTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVUvOzdibl2= MVvTRW5ITVJ?
human IM-9 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVrPc4o6UW6qaXLpeIlwdiCxZjDoeY1idiCLTT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVYvOjJibl2= NXyzNmRCW0GQR1XS
human HCE-4 cell M4\FSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU\XV282UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1WtOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU4Njl2IH7N M2PPZ3NCVkeHUh?=
human TYK-nu cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUTJcohq[mm2aX;uJI9nKGi3bXHuJHR[Uy2wdTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUW4MlczKG6P NUPxb|IxW0GQR1XS
human NCI-H748 cell Ml:yS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofsTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEe0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU6NjV2IH7N M2fUXnNCVkeHUh?=
human ABC-1 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWXJcohq[mm2aX;uJI9nKGi3bXHuJGFDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NkGuNkBvVQ>? MlnBV2FPT0WU
human CCRF-CEM cell M2DhSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1LZS2lvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03OS54ODDuUS=> NH[1N49USU6JRWK=
human EW-3 cell NH7pco9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWrjVFUxUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvQTVibl2= NFnzbYdUSU6JRWK=
human NCI-H2342 cell Mk\JS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mm\nTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKzOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oi53MTDuUS=> NEXSU|dUSU6JRWK=
human CNS cancer cells MlHxR5l1d3SxeHnjxsBie3OjeR?= Mn36R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR25UKGOjbnPldkBk\WyuczygS2k2OD14NDDuUS=> MV2xNVQ4OzRzOB?=
human SK-PN-DW cell NES0SoVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNVCQLVTXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlMvPzZibl2= MYHTRW5ITVJ?
human EB2 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoLmTY5pcWKrdHnvckBw\iCqdX3hckBGSjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygbYM2OD14NT6zOkBvVQ>? NUD6NIdnW0GQR1XS
human HUT78 cells NUnQRm1wWHKxbHnm[ZJifGmxbjDhd5NigQ>? NYjk[GNpPDhiaB?= NWXvfm1GSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWXQ4QCClZXzsd{Bi\nSncjC0PEBpenNiYomgdoV{[Xq3cnnuJJJm\HWldHnvckBie3OjeTygbYM2OD14NjDuUS=> NIHBPGYzPjV2MUW4Oy=>
human colon cancer cell line HCT15 M3\SdmN6fG:2b4jpZ:Kh[XO|YYm= NIfrNJA4OiCq MU\JckB3cXS{bzDjfZRwfG:6aXOgZYN1cX[rdImgZYdicW6|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJGhEXDF3IHHmeIVzKDd{IHjyJI9nKGS{dXeg[Zhxd3O3cnWg[IV1\XKvaX7l[EBjgSC2aHWgV3JDKGG|c3H5MEBKSzVyPUewJI5O MX2xOFk5ODZ5Mh?=
human HCT8 cells NIfnNW1EgXSxdH;4bYPDqGG|c3H5 NHfE[Fg4OiCq NIjHVmVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1R6IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9PFMhdk1? NF;xfHEyQDh2NUS0NS=>
human THP1 cells MVrDfZRwfG:6aXRCpIF{e2G7 MnvCOFghcA>? MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDUTHAyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;MD6xJO69VQ>? MV[yOVI2QTVzNR?=
human PC3 cells NWfZTmFLWHKxbHnm[ZJifGmxbjDhd5NigQ>? M1\V[FczKGh? MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhfHK7cHHuJIJtfWViZYjjcJV{cW:wIHHzd4F6NCCHQ{WwQVAvOTRizszN NVe1T2lJOTl4N{S5NFU>

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting.

p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane.

Beclin 1 / p62 / ATG5; 

PubMed: 29142609     


(A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C

GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; 

PubMed: 28553347     


(A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).

24901052 29142609 28553347
In vivo As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. [4]

Protocol

Animal Research:[4]
- Collapse
  • Animal Models: Rat bladder tumor model
  • Formulation: saline
  • Dosages: 400 μM
  • Administration: Intravesical treatment
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 66 mg/mL (197.38 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 334.37
Formula

C15H18N4O5

CAS No. 50-07-7
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

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Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02199327 Completed Drug: Mitomycin C|Drug: Interferon Alfa-2b Conjunctival Intraepithelial Neoplasia|Corneal Intraepithelial Neoplasia Coordinación de Investigación en Salud Mexico|Instituto Mexicano del Seguro Social|University of Guadalajara May 2014 Phase 4
NCT02015650 Unknown status Drug: Cetuximab|Drug: Mitomycin-C/ 5-Fluorouracil Head and Neck Neoplasms Medical University Innsbruck April 2014 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID