Mitomycin C

Catalog No.S8146

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Cited by 10 Publications

Protein Cell, 2019, 10.1007/s13238-019-0610-7

PubMed: 30796637 ( click the link to review the publication )

J Cell Physiol, 2019, 10.1002/jcp.28810

PubMed: 31093976 ( click the link to review the publication )

Front Physiol, 2019, 10:24

PubMed: 30745880 ( click the link to review the publication )

Br J Surg, 2019, 10.1002/bjs.11206

PubMed: 31197820 ( click the link to review the publication )

Int J Mol Sci, 2018, 20(1)

PubMed: 30591689 ( click the link to review the publication )

Biomed Pharmacother, 2018, 101:107-114

PubMed: 29477470 ( click the link to review the publication )

BMC Cancer, 2018, 18(1):426

PubMed: 29661159 ( click the link to review the publication )

Cancer Sci, 2018, 109(11):3450-3460

PubMed: 30191636 ( click the link to review the publication )

Oncogene, 2017, 10.1038/onc.2017.6

PubMed: 28218905 ( click the link to review the publication )

Oncol Lett, 2017, 14(6):8035-8041

PubMed: 29344246 ( click the link to review the publication )

1 Customer Review

MTT results of three HCC cell lines at 72 h after indicated treatments. Three independent experiments were carried out.

Cancer Sci, 2018, 109(11):3450-3460. Mitomycin C purchased from Selleck.

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Targets

DNA synthesis ^[1]

In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. ^[1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. ^[2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. ^[3]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
human NTERA-S-cl-D1 cell	M2WyNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NU[yZoN4UW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4zOWVvMEWg{txO	NYCybZdKW0GQR1XS
human MOLT-4 cell	MmfVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MU\Jcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOuNlVmNTB3IN88US=>	NF3CVVZUSU6JRWK=
human J82 cell	MlHiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHjNRopKdmirYnn0bY9vKG:oIHj1cYFvKEp6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuNVE6KG6P	NVT2SFZQW0GQR1XS
human 697 cell	NY\ad5FqT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MmrCTY5pcWKrdHnvckBw\iCqdX3hckA3QTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3Ojef-8kEBKSzVyPUCuNVI5KG6P	M1uydHNCVkeHUh?=
human KYSE-510 cell	MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NEnHNopKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtOVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zNEmgcm0>	NWjGTJlOW0GQR1XS
human NCI-H2170 cell	M{XEWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NXO0V4UxUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG1NUBvVQ>?	Mk\pV2FPT0WU
human BE-13 cell	MoKxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVf6OmZCUW6qaXLpeIlwdiCxZjDoeY1idiCERT2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTZ5IH7N	MULTRW5ITVJ?
human LC-2-ad cell	NWLwRXB[T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MlvwTY5pcWKrdHnvckBw\iCqdX3hckBNSy1{LXHkJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDlibl2=	MmTzV2FPT0WU
human IMR-5 cell	MkL3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4HxXmlvcGmkaYTpc44hd2ZiaIXtZY4hUU2ULUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlMxQCCwTR?=	MkPqV2FPT0WU
human EW-16 cell	M3LQWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NW\MTHpWUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzFibl2=	NEDZPVBUSU6JRWK=
human MC-IXC cell	MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NUDMeGxKUW6qaXLpeIlwdiCxZjDoeY1idiCPQz3JXGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ\|ODFOwG0>	NYrTfWl5W0GQR1XS
human SW872 cell	NYjlbnFlT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MX;Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD62O\|Yh\|ryP	M4n0NHNCVkeHUh?=
human NCI-H2228 cell	MoLmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYDaO4c5UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke5OkDPxE1?	MlO5V2FPT0WU
K562 leukemia cells	NXrtNos4T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NV;BR5pqUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNuIFnDOVA:OSCwTR?=	MVOxNlY6QTN6Nh?=
human NALM-6 cell	M3TYXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5CVE1vNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGuNFchdk1?	MkfUV2FPT0WU
AA8 cells	NEPS[nhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=	MmnxOEBp	NG\PclNKdmirYnn0c5J6KGGldHn2bZR6KG:oIHPvcZBwfW6mIH\vdkBCSThiY3XscJMhfG9icnXkeYNmKGOnbHyg[IVve2m2eTDifUA2OCViKHX4dI9{\WRidH:gZ49ueG:3bnSg[o9zKDRiaH;1dpMq	MnzBNlkxQTd2MR?=
human ES4 cell	MmjXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Ml3WTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O	NEO3c\|JUSU6JRWK=
human KE-37 cell	MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MXnJcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT62OEBvVQ>?	NVLTeIR6W0GQR1XS
human IST-MEL1 cell	MoDCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MUHJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43QCCwTR?=	NIPYVYRUSU6JRWK=
human ES8 cell	M2HHc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3:3bmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT63NUBvVQ>?	MVXTRW5ITVJ?
human MV-4-11 cell	MmHLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MXjJcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc{KG6P	MoHxV2FPT0WU
human 639-V cell	Mn;WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NGnEfotKdmirYnn0bY9vKG:oIHj1cYFvKDZ\|OT3WJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44PiCwTR?=	Mn;sV2FPT0WU
human OCI-AML2 cell	M3nYXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M2XoSGlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh7IH7N	NFrERYJUSU6JRWK=
human SK-LU-1 cell	MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NHvkXotKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzVMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ{IH7N	NYDiXpBUW0GQR1XS
human PSN1 cell	NF:1eZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MnLYTY5pcWKrdHnvckBw\iCqdX3hckBRW05zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj61OUBvVQ>?	MmDXV2FPT0WU
human REH cell	Mn7sS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnXNTY5pcWKrdHnvckBw\iCqdX3hckBTTUhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkW1JI5O	M13VUnNCVkeHUh?=
human SBC-5 cell	MoHDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NIrsRWlKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?=	MXfTRW5ITVJ?
human HT-3 cell	NYP5NWU2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnqyTY5pcWKrdHnvckBw\iCqdX3hckBJXC1\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Mj65N{BvVQ>?	NUfQbo5[W0GQR1XS
human SIG-M5 cell	Mn3RS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M2eyRWlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42OiCwTR?=	Mne5V2FPT0WU
human ES7 cell	M4XVcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNwNkWgcm0>	NYHoSIFXW0GQR1XS
human CHP-212 cell	M17jN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVjJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1{MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlM4KG6P	M1TzXXNCVkeHUh?=
human P12-ICHIKAWA cell	NFG4fIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MXTJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTRwN{mgcm0>	MUnTRW5ITVJ?
human HUTU-80 cell	NHrjZW1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M1vkbGlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDNibl2=	M{npR3NCVkeHUh?=
human P30-OHK cell	MkPrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1W2V2lvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDRibl2=	NE[2fnVUSU6JRWK=
human NCI-H1651 cell	M4jjWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MnrqTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2OVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njl7IH7N	NF7pXnBUSU6JRWK=
Chinese hamster V-C8 mutant cells	NYnXRogxS3m2b4TvfIlkyqCjc4PhfS=>	M4qxUlMh\GG7cx?=	M4DwPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEKUQ1GyMYRm\mmlaXXueEBEcGmwZYPlJIhidXO2ZYKgWk1EQCCvdYThcpQh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IGfTWFEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PSCwTR?=	NYDqdYN5OTh3MEWyPFQ>
human COR-L279 cell	MkTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NXfY[HNvUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVwNUSgcm0>	NFrVZZRUSU6JRWK=
human CMK cell	MmDqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYG2eWJGUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlg{KG6P	MnPUV2FPT0WU
human MHH-CALL-2 cell	NI\MN3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MnzoTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvQ1HMUE0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi5yNjDuUS=>	NYXWO4FoW0GQR1XS
human BV-173 cell	M4XUUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NX[4dFJCUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO\|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N	NVG2VpBGW0GQR1XS
human NCI-H209 cell	MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MojRTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOTdibl2=	NIHKUIhUSU6JRWK=
human NCI-H460 cell	MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NX3yfG1EUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ3OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZwNEWgcm0>	NXrzUYl6W0GQR1XS
human DU-145 cell	NIX0PVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NV75PIlbUW6qaXLpeIlwdiCxZjDoeY1idiCGVT2xOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjV{IH7N	M1q1THNCVkeHUh?=
SW480 colon cancer cell	MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NGPlPJBKdiC4aYTyc{BqdmirYnn0bY9vKG:oIGPXOFgxKGOxbH;uJINidmOncjDj[YxtKGyrbnWsJGlEPTB;NzDuUS=>	M3HTOVE6OjB\|NEm=
human 769-P cell	M3fLSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NGrvOnJKdmirYnn0bY9vKG:oIHj1cYFvKDd4OT3QJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yOSCwTR?=	M4PFcXNCVkeHUh?=
human ES1 cell	NEDlUYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MorxTY5pcWKrdHnvckBw\iCqdX3hckBGWzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkK5JI5O	NUT6TWJ2W0GQR1XS
human COLO-668 cell	MnKyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHnOcYJKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tOlY5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py53NTDuUS=>	NHrkPZVUSU6JRWK=
human NKM-1 cell	M{C3O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYLJcohq[mm2aX;uJI9nKGi3bXHuJG5MVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz64N{BvVQ>?	M{PKb3NCVkeHUh?=
human ES3 cell	MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3PQfGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz64PEBvVQ>?	NE\zc3NUSU6JRWK=
human SCC-3 cell	NX3ibnpQT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGjsWYdKdmirYnn0bY9vKG:oIHj1cYFvKFOFQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OiCwTR?=	M4rhT3NCVkeHUh?=
human SU-DHL-1 cell	M135PGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYTJcohq[mm2aX;uJI9nKGi3bXHuJHNWNUSKTD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE43OSCwTR?=	NIjod3BUSU6JRWK=
human ML-2 cell	MlTzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1NNTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD16Lke4JI5O	MUjTRW5ITVJ?
WiDr colon cancer cell	NEjCTYJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MVPJckB3cXS{bzDpcohq[mm2aX;uJI9nKFerRIKgZ49td25iY3HuZ4VzKGOnbHygcIlv\SxiSVO1NF0yOCCwTR?=	M4naZlE6OjB\|NEm=
human SF295 cell	NWTOUm9QT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NV65XXVYUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK5OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjR6IH7N	M2jJbnNCVkeHUh?=
human EW-7 cell	NXXROlBUT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M1XBNWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGyMlE1KG6P	NH\jfFFUSU6JRWK=
human H4 cell	NGDve3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4DvfWlvcGmkaYTpc44hd2ZiaIXtZY4hUDRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj60OEBvVQ>?	Mo[3V2FPT0WU
human LB2241-RCC cell	MmH2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M33t[GlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF\|LkG5JI5O	MkfTV2FPT0WU
human SR cell	M1foemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NW\wSoNOUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGzMlQ3KG6P	NH24[ZFUSU6JRWK=
human LB1047-RCC cell	MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NFHSWolKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz62JI5O	NV;wbm1WW0GQR1XS
human MCF7 cell	MnnxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NFu0[G5KdmirYnn0bY9vKG:oIHj1cYFvKE2FRkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46KG6P	NWPteINbW0GQR1XS
human ESS-1 cell	NV3LVVN1T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXjyfWF5UW6qaXLpeIlwdiCxZjDoeY1idiCHU2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl{IH7N	Mn;jV2FPT0WU
human NCI-H2122 cell	M2DR[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MnnJTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NjDuUS=>	NI\uVGdUSU6JRWK=
human 786-0 cell	NIfkbJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NITN[opKdmirYnn0bY9vKG:oIHj1cYFvKDd6Nj2wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvODFizszN	MkfMV2FPT0WU
human COLO-205 cell	NEDUWFZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3LNRmlvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz2yNFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC5\|MzFOwG0>	M3j5b3NCVkeHUh?=
human HAL-01 cell	MoHMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWHJcohq[mm2aX;uJI9nKGi3bXHuJGhCVC1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUG1Mlc{KM7:TR?=	MWXTRW5ITVJ?
K562 leukemia cells	NF\NbWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NXXLS4tmUW5idnn0do8hcW6qaXLpeI9zgSCjY4Tpeol1gSCjZ3HpcpN1KEt3NkKgcIV2c2WvaXGgZ4VtdHNiaX6geIhmKHC{ZYPlcoNmKG:oIIDkNkwhUUN3ME2xOU45KG6P	MUCxNlY6QTN6Nh?=
human MHH-ES-1 cell	MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2HUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvOjZibl2=	MmL5V2FPT0WU
human NUGC-3 cell	M2LCWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MVLJcohq[mm2aX;uJI9nKGi3bXHuJG5WT0NvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUG2Mlk2KG6P	MXjTRW5ITVJ?
human RPMI-8402 cell	MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MlKxTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLUi0NFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy5zMzDuUS=>	MYjTRW5ITVJ?
human ATN-1 cell	Mn[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NY\TbZkyUW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjN7IH7N	MoPEV2FPT0WU
human NCI-H441 cell	MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVfDcFVQUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ1OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF5Lk[gcm0>	NE[zOmhUSU6JRWK=
human LB996-RCC cell	NInOeHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MULJcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVE4NjZ6IH7N	NFm4NoVUSU6JRWK=
human CAL-148 cell	M1rGemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3LpTGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4Njl\|IH7N	M2fUXnNCVkeHUh?=
human CTV-1 cell	NFfRTllIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3nMO2lvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE43PyCwTR?=	NF62bXJUSU6JRWK=
human HOP-62 cell	NE[yZ4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4TtOWlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvOiCwTR?=	M1vwPXNCVkeHUh?=
human CAKI-1 cell	MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NEfVOZRKdmirYnn0bY9vKG:oIHj1cYFvKEODS1mtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjN{IH7N	M2L0eXNCVkeHUh?=
human PA-1 cell	Mmi0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHPnWHZKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{42OSCwTR?=	NVnhNohwW0GQR1XS
human HT-144 cell	NFLWeXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MUPJcohq[mm2aX;uJI9nKGi3bXHuJGhVNTF2NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKzMlc2KG6P	NEHib4JUSU6JRWK=
human LOUCY cell	MofVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEjzTlJKdmirYnn0bY9vKG:oIHj1cYFvKEyRVVPZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlYvOTlibl2=	NX22ZVJUW0GQR1XS
human BPH-1 cell	M3qxUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M4Lpd2lvcGmkaYTpc44hd2ZiaIXtZY4hSlCKLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU46KG6P	MXPTRW5ITVJ?
human LS-1034 cell	NYC4NXI2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MofOTY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMEO0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvOTZibl2=	NWj5O\|diW0GQR1XS
human 23132-87 cell	NXHCfGo{T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NH7ReIRKdmirYnn0bY9vKG:oIHj1cYFvKDJ\|MUOyMVg4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwNUOgcm0>	MWrTRW5ITVJ?
human BB30-HNC cell	NXztNYN3T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		Moq2TY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjZzIH7N	NIPDb4ZUSU6JRWK=
human CAL-51 cell	M1r4VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MXvJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC13MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOwMlg3KG6P	MoThV2FPT0WU
human ALL-PO cell	NGLDcWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M{\OPWlvcGmkaYTpc44hd2ZiaIXtZY4hSUyOLWDPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvQThibl2=	MmC3V2FPT0WU
human 5637 cell	NEnDdnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NHrWUopKdmirYnn0bY9vKG:oIHj1cYFvKDV4M{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNU46OyCwTR?=	M3ftO3NCVkeHUh?=
MCF-7 cell	NWnvXpRITnWwY4Tpc44h[XO\|YYm=		NWqyTYVwSW62aYT1cY9zKHCxdHXuZ5khd25iaIXtZY4h[nKnYYP0JG1ETi15IHPlcIwhdGmwZYOsJGlEPTB;M{KuNkBvVQ>?	NFTIdmIyQTB4MUC5
human KYSE-150 cell	NYXBWHhpT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NGPPT5FKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtNVUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwMEmgcm0>	MV3TRW5ITVJ?
human RS4-11 cell	MnPYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHrPSpJKdmirYnn0bY9vKG:oIHj1cYFvKFKVND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1Njh4IH7N	NV3tTGJ2W0GQR1XS
human A3-KAW cell	NFPSZlRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3TCTGlvcGmkaYTpc44hd2ZiaIXtZY4hSTNvS1HXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|QvQTZibl2=	M1PQdHNCVkeHUh?=
human NCI-H719 cell	NYHYUYVLT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MlL0TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEexPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjF{IH7N	NVvLd\|VHW0GQR1XS
human GI-1 cell	M4raemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3TKd2lvcGmkaYTpc44hd2ZiaIXtZY4hT0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUO1MlE3KG6P	M2TZS3NCVkeHUh?=
human HEL cell	Ml;iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN3Lkigcm0>	Mmr6V2FPT0WU
human TE-8 cell	MonVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1\|NT64OkBvVQ>?	M{Cyd3NCVkeHUh?=
human HT-29 cell	M3vRPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NVPxbGU2UW6qaXLpeIlwdiCxZjDoeY1idiCKVD2yPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjB{IH7N	M1\n[nNCVkeHUh?=
human SW1783 cell	M2T2cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NHPTbXBKdmirYnn0bY9vKG:oIHj1cYFvKFOZMUe4N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVM5NjV6IH7N	M4L1ZXNCVkeHUh?=
human CGTH-W-1 cell	NGXRS5JIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlPRTY5pcWKrdHnvckBw\iCqdX3hckBET1SKLWetNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NiCLQ{WwQVM5Njd2IH7N	MUnTRW5ITVJ?
human MEL-HO cell	NEH5dGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NYXDTFFVUW6qaXLpeIlwdiCxZjDoeY1idiCPRVytTG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{QS52IH7N	MkTjV2FPT0WU
human SW620 cell	NF;LRlFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NILSfm9KdmirYnn0bY9vKG:oIHj1cYFvKFOZNkKwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|kvPzlibl2=	M2X6Z3NCVkeHUh?=
Human Caki-1 Renal CellCarcinoma Cell	M2fMU2Z2dmO2aX;uJIF{e2G7	M1LBR\|k3KGh?	MlXkTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiSIXtZY4hS2GtaT2xJHJmdmGuIFPlcIxE[XKlaX7vcYEhS2WubDDMbY5meyBqQ1S3NEsqKGG2IEm2eIghcG:3cjygbYM2OD12MDDuUS=>	MV:xOVc1OzF5OB?=
human CH1 (ovarian) tumor cell	M{LWUWN6fG:2b4jpZ:Kh[XO\|YYm=		MoDDWIhmKGOxbYDveY5lKHejczDleoFtfWG2ZXSg[o9zKHSqZTDjfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDTFEhMG:4YYLpZY4qKHS3bX;yJINmdGxibHnu[ZMtKEmFNUC9OFAhdk1?	NYLlNYpXOTB4OUi0OFQ>
human HT-29 (colon) tumor cell	M1T2NmN6fG:2b4jpZ:Kh[XO\|YYm=		M1H5SXRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliKHPvcI9vMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P	M3PZWVExPjl6NES0
human A549 cells	MnHrR5l1d3SxeHnjxsBie3OjeR?=	M13DcVQ5KGh?	MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;NECgcm0>	NIDlT3YzPTJ3OUWxOS=>
human ME-180 cell	NH;BdoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4TLcGlvcGmkaYTpc44hd2ZiaIXtZY4hVUVvMUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFAvOTFibl2=	MWDTRW5ITVJ?
human CAL-27 cell	M1uxfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Mn25TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?=	Mn\yV2FPT0WU
human A431 cell	M4jtO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MkjVTY5pcWKrdHnvckBw\iCqdX3hckBCPDNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NEOuO\|chdk1?	M2m2PXNCVkeHUh?=
human SW954 cell	NVnSNGtiT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnL1TY5pcWKrdHnvckBw\iCqdX3hckBUXzl3NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUS0MlkyKG6P	M33CR3NCVkeHUh?=
human CAL-39 cell	M17oZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MXzJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC1\|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUS2MlQ6KG6P	MUDTRW5ITVJ?
human LU-134-A cell	NUTMU2x6T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHrGXlRKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwN{Kgcm0>	M4TudHNCVkeHUh?=
human DU-4475 cell	NXfDWHloT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MYLJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{41PyCwTR?=	M2rZPXNCVkeHUh?=
P388 cells (P388/S) cells	NVf3XVZnTnWwY4Tpc44h[XO\|YYm=		NGP2OZpGfmGudXH0bY9vKG:oIHnubIljcXSxcomgZYN1cX[rdImgZYdicW6\|dDDkdpVoKHOnboPpeIl3\SCSM{i4JINmdGy\|IDjQN\|g5N1NrIHPlcIx{NCCLQ{WwQVQ5KG6P	MYm4OVQ1OTh\|
human DEL cell	MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NXnNZ5doUW6qaXLpeIlwdiCxZjDoeY1idiCGRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PE4{QSCwTR?=	MVjTRW5ITVJ?
human HGC-27 cell	NI\tdlJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M4jLXmlvcGmkaYTpc44hd2ZiaIXtZY4hUEeFLUK3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvOjlibl2=	MnvNV2FPT0WU
human RH-1 cell	MnjES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MmP6TY5pcWKrdHnvckBw\iCqdX3hckBTUC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NEmuOVchdk1?	NYj2VYo3W0GQR1XS
HL-60 cells	MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MnPnTY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDD3ZZMhe3S3ZHnl[EBqdiCqdX3hckBxem:veXXsc4N6fGmlIHzleYtmdWmlIDjIUE03OCliY3XscJMtKEmFNUC9OVAhdk1?	NVL6WFE{QDdyOUGxNS=>
human A2780 (ovarian) tumor cell	MWDDfZRwfG:6aXRCpIF{e2G7		NHvFU45VcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIDjveoFzcWGwKTD0eY1weiClZXzsJIxqdmW\|LDDJR\|UxRTVyIH7N	MUWxNFY6QDR2NB?=
human SK-MES-1 cell	MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NWrMR4s5UW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVzLkGyJI5O	NFLjcXdUSU6JRWK=
human MEL-JUSO cell	MmjXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MVzJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2MVWPPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOjVibl2=	NGLMZ4FUSU6JRWK=
human VA-ES-BJ cell	NHnhNZlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NFHMbFNKdmirYnn0bY9vKG:oIHj1cYFvKF[DLVXTMWJLKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PTJwMU[gcm0>	M17WPHNCVkeHUh?=
human EW-13 cell	MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MlK0TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUWyMlUyKG6P	Mnz1V2FPT0WU
human Ca-Ski cell	NYXGW5BIT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3Hab2lvcGmkaYTpc44hd2ZiaIXtZY4hS2FvU3vpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVMvPzVibl2=	NGX5[odUSU6JRWK=
human LXF-289 cell	NUnnRWZnT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M4PLd2lvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU2NjN5IH7N	M3X6WXNCVkeHUh?=
human IM-9 cell	MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYH0U5NbUW6qaXLpeIlwdiCxZjDoeY1idiCLTT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVYvOjJibl2=	M{\tWnNCVkeHUh?=
human HCE-4 cell	NV3rSGFZT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MmLGTY5pcWKrdHnvckBw\iCqdX3hckBJS0VvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUW3Mlk1KG6P	MXjTRW5ITVJ?
human TYK-nu cell	MlK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M4DXVmlvcGmkaYTpc44hd2ZiaIXtZY4hXFmNLX71JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVgvPzJibl2=	MlzMV2FPT0WU
human NCI-H748 cell	Ml3RS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1;rSGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3OFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02QS53NDDuUS=>	M3L6ZnNCVkeHUh?=
human ABC-1 cell	MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NEj1O3BKdmirYnn0bY9vKG:oIHj1cYFvKEGEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvOiCwTR?=	MUXTRW5ITVJ?
human CCRF-CEM cell	M2jxe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3vacmlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03OS54ODDuUS=>	NWPUe3V4W0GQR1XS
human EW-3 cell	NVmxNVBQT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M{XseWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPU[xMlk2KG6P	M3npS3NCVkeHUh?=
human NCI-H2342 cell	MlvOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MoDpTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKzOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oi53MTDuUS=>	Ml[yV2FPT0WU
human CNS cancer cells	NGS1R41EgXSxdH;4bYPDqGG\|c3H5		NGH3Tm1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEVlNiY3HuZ4VzKGOnbHzzMEBIUTVyPU[0JI5O	MX2xNVQ4OzRzOB?=
human SK-PN-DW cell	MlXJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NV;Idm9rUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3QUk1FXyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTZ\|Lke2JI5O	MY\TRW5ITVJ?
human EB2 cell	NGrFUmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NVqx[mFTUW6qaXLpeIlwdiCxZjDoeY1idiCHQkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhcWN3ME22OU4{PiCwTR?=	MUPTRW5ITVJ?
human HUT78 cells	MomwVJJwdGmoZYLheIlwdiCjc4PhfS=>	NHnseo01QCCq	NF7lc5hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjVWFc5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDy[ZNignW{aX6gdoVlfWO2aX;uJIF{e2G7LDDpZ\|UxRTZ4IH7N	NWfBV4hmOjZ3NEG1PFc>
human colon cancer cell line HCT15	NY\lSmd3S3m2b4TvfIlkyqCjc4PhfS=>	M1[2cFczKGh?	MYfJckB3cXS{bzDjfZRwfG:6aXOgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJGhEXDF3IHHmeIVzKDd{IHjyJI9nKGS{dXeg[Zhxd3O3cnWg[IV1\XKvaX7l[EBjgSC2aHWgV3JDKGG\|c3H5MEBKSzVyPUewJI5O	NWriW\|ZjOTR7OEC2O\|I>
human HCT8 cells	NFXPb3lEgXSxdH;4bYPDqGG\|c3H5	NVzyV\|REPzJiaB?=	Mn;nR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyPUizJI5O	M4m1W\|E5QDR3NESx
human THP1 cells	MnH3R5l1d3SxeHnjxsBie3OjeR?=	NGG5[2k1QCCq	MmrVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWGhROSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBKSzVyPUCuNUDPxE1?	NFmwZY4zPTJ3OUWxOS=>
human PC3 cells	M3HZVXBzd2yrZnXyZZRqd25iYYPzZZk>	NILHXYI4OiCq	NXn2SZNRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR\|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IITyfZBidiCkbIXlJIV5[2y3c3nvckBie3OjeTygSWM2OD1yLkG0JO69VQ>?	NEnNelEyQTZ5NEmwOS=>

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting. p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane. Beclin 1 / p62 / ATG5; PubMed: 29142609 Oncol Lett (A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; PubMed: 28553347 Neural Regen Res (A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).	24901052 29142609 28553347

In vivo

As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. ^[4]

Protocol

Animal Research:^[4]	+ Expand Animal Models: Rat bladder tumor model Formulation: saline Dosages: 400 μM Administration: Intravesical treatment (Only for Reference)

References

[4] Jankun J, et al. Int J Oncol. 2014, 44(1), 147-152.

+ Expand

Solubility (25°C)

In vitro	DMSO	66 mg/mL (197.38 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Mitomycin C SDF

Molecular Weight	334.37
Formula	C₁₅H₁₈N₄O₅
CAS No.	50-07-7
Storage	3 years -20°C powder
Storage	2 years -80°C in solvent
Synonyms	N/A

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-03-27)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT03875911	Recruiting	Glaucoma Open-Angle Primary\|Glaucoma\|Open Angle Glaucoma\|Glaucoma Open-Angle	University of California Los Angeles	March 30 2019	Phase 4
NCT03875911	Recruiting	Glaucoma Open-Angle Primary\|Glaucoma\|Open Angle Glaucoma\|Glaucoma Open-Angle	University of California Los Angeles	March 30 2019	Phase 4
NCT03658304	Recruiting	Urothelial Carcinoma	University of Florida	December 5 2018	Phase 2
NCT03658304	Recruiting	Urothelial Carcinoma	University of Florida	December 5 2018	Phase 2
NCT03664869	Not yet recruiting	Bladder Cancer	Turku University Hospital\|Finnbladder	October 26 2018	Phase 3
NCT03664869	Not yet recruiting	Bladder Cancer	Turku University Hospital\|Finnbladder	October 26 2018	Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products0

SCR7 ^New

SCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ). It increases the efficiency of HDR-mediated genome editing up to 19-fold using CRISPR/Cas9 in mammalian cells and mouse embryos.
Blasticidin S HCl ^New

Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes.
YK-4-279 ^New

YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).
Cisplatin

Cisplatin is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor cells. DMF is recommended for dissolution.

Features:One of the most widely used and most potent chemotherapeutic agents.
Gemcitabine HCl

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

Features:Gemcitabine has been used to treat pancreatic cancer and has demonstrated effective anti-tumor activity.
Oxaliplatin

Oxaliplatin inhibits DNA synthesis by conforming DNA adducts in RT4, TCCSUP, A2780, HT-29, U-373MG, U-87MG, SK-MEL-2, and HT-144 cells.
Bleomycin Sulfate

Bleomycin Sulfate is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.
Gemcitabine

Gemcitabine, a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy.
Fluorouracil (5-Fluoracil, 5-FU)

Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells.
Carboplatin

Carboplatin is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells.

Features:A DNA synthesis inhibitor.

Choose Your Country or Region

By Signaling Pathways

By product type

Mitomycin C

Cited by 10 Publications

1 Customer Review

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Dilution Calculator

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-03-27)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products0

Choose Your Country or Region

By Signaling Pathways

By product type

Mitomycin C

Cited by 10 Publications

1 Customer Review

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Dilution Calculator

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-03-27)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products0

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)