Mitomycin C

Catalog No.S8146

Molecular Weight(MW): 334.37

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Cited by 16 Publications

Clin Cancer Res, 2019, 25(6):1957-1969

PubMed: 30482778 ( click the link to review the publication )

Cell Rep, 2019, 27(11):3331-3344

PubMed: 31189115 ( click the link to review the publication )

Protein Cell, 2019, 10.1007/s13238-019-0610-7

PubMed: 30796637 ( click the link to review the publication )

J Cell Physiol, 2019, 10.1002/jcp.28810

PubMed: 31093976 ( click the link to review the publication )

Front Physiol, 2019, 10:24

PubMed: 30745880 ( click the link to review the publication )

Br J Surg, 2019, 10.1002/bjs.11206

PubMed: 31197820 ( click the link to review the publication )

Sci Adv, 2018, 4(9):eaar4666

PubMed: 30263952 ( click the link to review the publication )

Int J Mol Sci, 2018, 20(1)

PubMed: 30591689 ( click the link to review the publication )

Biomed Pharmacother, 2018, 101:107-114

PubMed: 29477470 ( click the link to review the publication )

Cancer Manag Res, 2018, 10:6791-6802

PubMed: 30588088 ( click the link to review the publication )

Chem Biol Interact, 2018, 296:26-33

PubMed: 30217479 ( click the link to review the publication )

BMC Cancer, 2018, 18(1):426

PubMed: 29661159 ( click the link to review the publication )

Cancer Sci, 2018, 109(11):3450-3460

PubMed: 30191636 ( click the link to review the publication )

Oncogene, 2017, 10.1038/onc.2017.6

PubMed: 28218905 ( click the link to review the publication )

Oncol Lett, 2017, 14(6):8035-8041

PubMed: 29344246 ( click the link to review the publication )

Oncotarget, 2017, 8(70):115164-115178

PubMed: 29383150 ( click the link to review the publication )

1 Customer Review

MTT results of three HCC cell lines at 72 h after indicated treatments. Three independent experiments were carried out.

Cancer Sci, 2018, 109(11):3450-3460. Mitomycin C purchased from Selleck.

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Targets

DNA synthesis ^[1]

In vitro

Mitomycin C, by inducing DNA interstrand crosslinks, physically blocks DNA replication, recombination, and RNA transcription. ^[1] Mitomycin C potentiates TRAIL-induced apoptosis in HCT116 (p53-/-) colon cancer cells and sensitizes TRAIL-resistant colon cancer cells HT-29 to the cytokine by through JNK-independent upregulation of death receptors. ^[2] In different human cancer cell lines, such OVCAR-5 (ovary), HT-29 (colon), SK-N-MC (neuroblastoma), HEP-2 (liver), COLO-205 (colon), NIH-OVCAR-3 (ovary) and A-549 (lung) cells, Mitomycin C shows cytotoxic activity. ^[3]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
human NTERA-S-cl-D1 cell	NWPYPHM2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVfJcohq[mm2aX;uJI9nKGi3bXHuJG5VTVKDLWOtZ4wuTDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkKx[U0xPSEQvF2=	NUGxZWFUW0GQR1XS
human MOLT-4 cell	Mn\aS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1jPRWlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPWVvMEWg{txO	MWXTRW5ITVJ?
human J82 cell	M4Hae2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1W5b2lvcGmkaYTpc44hd2ZiaIXtZY4hUjh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6xNVkhdk1?	NGjuUIdUSU6JRWK=
human 697 cell	NELrdHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NYSy[VhHUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4Phfg+9lCCLQ{WwQVAvOTJ6IH7N	M33vZXNCVkeHUh?=
human KYSE-510 cell	NXvsWGhHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NXW4dI56UW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVUyOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwMUS5JI5O	NFzq[W1USU6JRWK=
human NCI-H2170 cell	M{TXV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NVrqO\|ZCUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG1NUBvVQ>?	MVnTRW5ITVJ?
human BE-13 cell	M3zXcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYfJcohq[mm2aX;uJI9nKGi3bXHuJGJGNTF\|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6xOlchdk1?	M3znS3NCVkeHUh?=
human LC-2-ad cell	MkL4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVLkOYZjUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2yMYFlKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5{NEmgcm0>	Ml\HV2FPT0WU
human IMR-5 cell	M1frRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MXTJcohq[mm2aX;uJI9nKGi3bXHuJGlOWi13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MD6zNFghdk1?	MUHTRW5ITVJ?
human EW-16 cell	Mn\nS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnO4TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuN\|Ehdk1?	NYTvXm5oW0GQR1XS
human MC-IXC cell	M3y4Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MmCyTY5pcWKrdHnvckBw\iCqdX3hckBOSy2LWFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY{QCEQvF2=	M2fH[3NCVkeHUh?=
human SW872 cell	NUPWUHFLT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MnnJTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUCuOlc3KM7:TR?=	MV\TRW5ITVJ?
human NCI-H2228 cell	NXG5V3RyT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHrTUGhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlIzQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTBwN{m2JO69VQ>?	MX;TRW5ITVJ?
K562 leukemia cells	NYTZcXZFT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NIHHfWZKdiC4aYTyc{BqdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUzV4MjDs[ZVs\W2rYTDj[YxteyxiSVO1NF0yKG6P	MkLhNVI3QTl\|OE[=
human NALM-6 cell	MorZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3\NSGlvcGmkaYTpc44hd2ZiaIXtZY4hVkGOTT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xPyCwTR?=	Mn7EV2FPT0WU
AA8 cells	NFWwfINIem:5dHigbY5pcWKrdHnvckBie3OjeR?=	NYftbJJ5PCCq	MnTUTY5pcWKrdH;yfUBi[3Srdnn0fUBw\iClb33wc5Vv\CCob4KgRWE5KGOnbHzzJJRwKHKnZIXj[UBk\WyuIHTlcpNqfHliYomgOVAmKCineIDvd4VlKHSxIHPvcZBwfW6mIH\vdkA1KGixdYLzLS=>	NVP2NYNNOjlyOUe0NS=>
human ES4 cell	MlnIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVvnNJBnUW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlU3KG6P	Mn3wV2FPT0WU
human KE-37 cell	MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MT62OEBvVQ>?	NIHaPGhUSU6JRWK=
human IST-MEL1 cell	NYq3Z\|B7T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MWPJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43QCCwTR?=	NXTGNIxqW0GQR1XS
human ES8 cell	M4r6bmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NITXcnBKdmirYnn0bY9vKG:oIHj1cYFvKEWVODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGuO\|Ehdk1?	NX75U4FiW0GQR1XS
human MV-4-11 cell	MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MVjJcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc{KG6P	MmDNV2FPT0WU
human 639-V cell	NYXGTmFbT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NFjibHdKdmirYnn0bY9vKG:oIHj1cYFvKDZ\|OT3WJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44PiCwTR?=	M3r0b3NCVkeHUh?=
human OCI-AML2 cell	NXnRXppvT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NX24[IFqUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTFwOEmgcm0>	NUnjPWJ7W0GQR1XS
human SK-LU-1 cell	MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4TnXWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTGWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOjJibl2=	NFPUVZZUSU6JRWK=
human PSN1 cell	MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3\uOmlvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKuOVUhdk1?	MlXnV2FPT0WU
human REH cell	NVLsVWtHT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MWHJcohq[mm2aX;uJI9nKGi3bXHuJHJGUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTJwNUWgcm0>	MXPTRW5ITVJ?
human SBC-5 cell	MmrMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEjPd5JKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk42QSCwTR?=	NUXTWXRpW0GQR1XS
human HT-3 cell	NV3MSnRUT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NHrTc3BKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlk{KG6P	NUSye2tYW0GQR1XS
human SIG-M5 cell	NGG3Z49Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MlXJTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlUzKG6P	M4LQb3NCVkeHUh?=
human ES7 cell	NYjwb5B2T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVTJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTNwNkWgcm0>	NIDZdFBUSU6JRWK=
human CHP-212 cell	NHj1TWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NVO4bGtQUW6qaXLpeIlwdiCxZjDoeY1idiCFSGCtNlEzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5\|NzDuUS=>	M4jYbnNCVkeHUh?=
human P12-ICHIKAWA cell	NF\DWmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MWDJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTRwN{mgcm0>	MUTTRW5ITVJ?
human HUTU-80 cell	NIraeXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NEjyVG1KdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njh\|IH7N	M4jGS3NCVkeHUh?=
human P30-OHK cell	NV7zPW5RT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		Mn3FTY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE45PCCwTR?=	MmW2V2FPT0WU
human NCI-H1651 cell	NFu2fY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NYHZcmxHUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE3PTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Lkm5JI5O	M37IRnNCVkeHUh?=
Chinese hamster V-C8 mutant cells	M1vlTGN6fG:2b4jpZ:Kh[XO\|YYm=	NVvqO4xzOyCmYYnz	M4WyWmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEKUQ1GyMYRm\mmlaXXueEBEcGmwZYPlJIhidXO2ZYKgWk1EQCCvdYThcpQh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IGfTWFEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PSCwTR?=	NIfJdGUyQDVyNUK4OC=>
human COR-L279 cell	MlruS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYexRppIUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTVwNUSgcm0>	M3\BfnNCVkeHUh?=
human CMK cell	MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MkWyTY5pcWKrdHnvckBw\iCqdX3hckBEVUtiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkizJI5O	NX[3boMxW0GQR1XS
human MHH-CALL-2 cell	MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NX\2eYQ5UW6qaXLpeIlwdiCxZjDoeY1idiCPSFitR2FNVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nj6wOkBvVQ>?	NHKwOoNUSU6JRWK=
human BV-173 cell	M2rGT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NXT3TWZTUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO\|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB5IH7N	NEXBfXpUSU6JRWK=
human NCI-H209 cell	Mm\TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MoD2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOTdibl2=	NHPJRo9USU6JRWK=
human NCI-H460 cell	NWfiTXdLT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NIDTXnJKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOFYxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi52NTDuUS=>	M17uN3NCVkeHUh?=
human DU-145 cell	MmTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MYPJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTF2NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPU[uOVIhdk1?	M1PTeXNCVkeHUh?=
SW480 colon cancer cell	MnPSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NUO2S5hLUW5idnn0do8hcW6qaXLpeIlwdiCxZjDTW\|Q5OCClb3zvckBk[W6lZYKgZ4VtdCCuaX7lMEBKSzVyPUegcm0>	Ml75NVkzODN2OR?=
human 769-P cell	MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MlfSTY5pcWKrdHnvckBw\iCqdX3hckA4PjlvUDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUeuNVEhdk1?	MnSzV2FPT0WU
human ES1 cell	NUTZXYZbT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3X3WGlvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;Nz6yPUBvVQ>?	MWPTRW5ITVJ?
human COLO-668 cell	MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NYnYfoQ3UW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVY3QCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTdwNUWgcm0>	NELCfXpUSU6JRWK=
human NKM-1 cell	MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3\Ue2lvcGmkaYTpc44hd2ZiaIXtZY4hVkuPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23Mlg{KG6P	NYK3e5d[W0GQR1XS
human ES3 cell	MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MoPhTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15Lki4JI5O	MXfTRW5ITVJ?
human SCC-3 cell	M4\iXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NX7Ue5ZMUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1OtN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPTJibl2=	MWjTRW5ITVJ?
human SU-DHL-1 cell	M{PocWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Ml3MTY5pcWKrdHnvckBw\iCqdX3hckBUXS2GSFytNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPjFibl2=	NX;wR\|MzW0GQR1XS
human ML-2 cell	M2jQdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M3zqc2lvcGmkaYTpc44hd2ZiaIXtZY4hVUxvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUiuO\|ghdk1?	M1:2NXNCVkeHUh?=
WiDr colon cancer cell	NGOzNYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M2CxemlvKH[rdILvJIlvcGmkaYTpc44hd2ZiV3nEdkBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR\|UxRTFyIH7N	MVKxPVIxOzR7
human SF295 cell	NYjxRWVIT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NVGz[Y5GUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK5OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjR6IH7N	MWrTRW5ITVJ?
human EW-7 cell	M17jXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M{m0NGlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGyMlE1KG6P	M4nINXNCVkeHUh?=
human H4 cell	M4TjeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		Mn;ETY5pcWKrdHnvckBw\iCqdX3hckBJPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF{LkS0JI5O	NIL2[5BUSU6JRWK=
human LB2241-RCC cell	NW\xOVB[T3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3XGeWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF\|LkG5JI5O	M4HLcXNCVkeHUh?=
human SR cell	MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NH\1emZKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuOFYhdk1?	M2jw[XNCVkeHUh?=
human LB1047-RCC cell	MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MmDYTY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwNjDuUS=>	NHTJfohUSU6JRWK=
human MCF7 cell	M2T3NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M2HwcGlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUGzMlkhdk1?	NFXNW4hUSU6JRWK=
human ESS-1 cell	NHzhRmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MVrJcohq[mm2aX;uJI9nKGi3bXHuJGVUWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUOuPVIhdk1?	NEjseFdUSU6JRWK=
human NCI-H2122 cell	MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		Mm\2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NjDuUS=>	NHzyXHZUSU6JRWK=
human 786-0 cell	M1X6cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M2nwNmlvcGmkaYTpc44hd2ZiaIXtZY4hPzh4LUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE4xOSEQvF2=	MXrTRW5ITVJ?
human COLO-205 cell	MkTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NVfabYVGUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVIxPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF2LkOzJO69VQ>?	NXPPN4Z1W0GQR1XS
human HAL-01 cell	MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NHu4UmxKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2Njd\|IN88US=>	MWfTRW5ITVJ?
K562 leukemia cells	MljiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MX3JckB3cXS{bzDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4SgT\|U3OiCuZYXr[Y1q[SClZXzsd{BqdiC2aHWgdJJme2WwY3Wgc4YheGR{LDDJR\|UxRTF3Lkigcm0>	NI\OSIYyOjZ7OUO4Oi=>
human MHH-ES-1 cell	M{fkRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NY\KSY9PUW6qaXLpeIlwdiCxZjDoeY1idiCPSFitSXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTF4LkK2JI5O	NVftXmF4W0GQR1XS
human NUGC-3 cell	MlzlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M1f3WWlvcGmkaYTpc44hd2ZiaIXtZY4hVlWJQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvQTVibl2=	NWXBTmRpW0GQR1XS
human RPMI-8402 cell	NH:1d5RIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MWjJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvOESwNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjF\|IH7N	M1[4e3NCVkeHUh?=
human ATN-1 cell	NHO2OZNIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NFPUdWVKdmirYnn0bY9vKG:oIHj1cYFvKEGWTj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOzlibl2=	MVLTRW5ITVJ?
human NCI-H441 cell	Mk\PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NEL3cmdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOFQyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwNjDuUS=>	Mo\wV2FPT0WU
human LB996-RCC cell	NHzGRYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MmW4TY5pcWKrdHnvckBw\iCqdX3hckBNSjl7Nj3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS5iSVO1NF0yPy54ODDuUS=>	Mm\UV2FPT0WU
human CAL-148 cell	NYrlNmNzT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		NVrpbXhRUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwOUOgcm0>	M1Sx[3NCVkeHUh?=
human CTV-1 cell	M{mySGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MWDJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;MUiuOlchdk1?	M3PsS3NCVkeHUh?=
human HOP-62 cell	MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M4rsZmlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvOiCwTR?=	MVrTRW5ITVJ?
human CAKI-1 cell	NXLLVnVzT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MVnJcohq[mm2aX;uJI9nKGi3bXHuJGNCU0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUKzMlMzKG6P	Moe3V2FPT0WU
human PA-1 cell	M4LPdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYPJcohq[mm2aX;uJI9nKGi3bXHuJHBCNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz61NUBvVQ>?	NH7xOWhUSU6JRWK=
human HT-144 cell	M{DOfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M4PFVmlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPzVibl2=	NEXHNWFUSU6JRWK=
human LOUCY cell	MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NUH6dIZvUW6qaXLpeIlwdiCxZjDoeY1idiCOT2XDXUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3NjF7IH7N	NXXBW4J3W0GQR1XS
human BPH-1 cell	Ml7BS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		M3XabWlvcGmkaYTpc44hd2ZiaIXtZY4hSlCKLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU46KG6P	MXrTRW5ITVJ?
human LS-1034 cell	MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MoD5TY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMEO0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|AvOTZibl2=	NVm4fnJkW0GQR1XS
human 23132-87 cell	MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NFm1fJJKdmirYnn0bY9vKG:oIHj1cYFvKDJ\|MUOyMVg4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwNUOgcm0>	NXT5fmlsW0GQR1XS
human BB30-HNC cell	M2\aUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1zLdmlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ\|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC54MTDuUS=>	Mm\4V2FPT0WU
human CAL-51 cell	M3vqb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NWL0eItSUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC56NjDuUS=>	M1fMeXNCVkeHUh?=
human ALL-PO cell	MoXnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NHjBSIlKdmirYnn0bY9vKG:oIHj1cYFvKEGOTD3QU{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjl6IH7N	NYn5Rnh3W0GQR1XS
human 5637 cell	NIHnUmxIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M37GVGlvcGmkaYTpc44hd2ZiaIXtZY4hPTZ\|NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUOxMlk{KG6P	Mn7EV2FPT0WU
MCF-7 cell	NH;IdWVHfW6ldHnvckBie3OjeR?=		MkHoRY51cXS3bX;yJJBwfGWwY4mgc44hcHWvYX6gZpJm[XO2IF3DSk04KGOnbHygcIlv\XNuIFnDOVA:OzJwMjDuUS=>	MWWxPVA3OTB7
human KYSE-150 cell	NHG5ZmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NUfzO3FKUW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVE2OCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN2LkC5JI5O	MnjRV2FPT0WU
human RS4-11 cell	M122Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NHPVSpBKdmirYnn0bY9vKG:oIHj1cYFvKFKVND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1Njh4IH7N	MnTmV2FPT0WU
human A3-KAW cell	Mkn4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NV3uOotkUW6qaXLpeIlwdiCxZjDoeY1idiCDMz3LRXch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC57NjDuUS=>	Mn\4V2FPT0WU
human NCI-H719 cell	NGTK[nJIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NWPkZ\|dpUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFcyQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTN3LkGyJI5O	NEKxbodUSU6JRWK=
human GI-1 cell	MnLZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Mn\6TY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuNVYhdk1?	MYPTRW5ITVJ?
human HEL cell	Mk[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NES5fYtKdmirYnn0bY9vKG:oIHj1cYFvKEiHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUO1Mlghdk1?	MV3TRW5ITVJ?
human TE-8 cell	NF;kOJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MorFTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;M{WuPFYhdk1?	NF;yO3JUSU6JRWK=
human HT-29 cell	M1r1S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NEjTUmpKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N\|YvODJibl2=	NIezVWxUSU6JRWK=
human SW1783 cell	MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M1rjb2lvcGmkaYTpc44hd2ZiaIXtZY4hW1dzN{izJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvKEmFNUC9N\|gvPThibl2=	M3noXnNCVkeHUh?=
human CGTH-W-1 cell	NGP4dYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NH20V5hKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwIFnDOVA:OzhwN{Sgcm0>	MojlV2FPT0WU
human MEL-HO cell	M4D2TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MYLJcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2KTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUO5MlQhdk1?	MlWxV2FPT0WU
human SW620 cell	MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVWzXXByUW6qaXLpeIlwdiCxZjDoeY1idiCVV{[yNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6Njd7IH7N	MYrTRW5ITVJ?
Human Caki-1 Renal CellCarcinoma Cell	NIfwOYxHfW6ldHnvckBie3OjeR?=	M3LFSFk3KGh?	Mkf3TY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiSIXtZY4hS2GtaT2xJHJmdmGuIFPlcIxE[XKlaX7vcYEhS2WubDDMbY5meyBqQ1S3NEsqKGG2IEm2eIghcG:3cjygbYM2OD12MDDuUS=>	MX:xOVc1OzF5OB?=
human CH1 (ovarian) tumor cell	NYf4RWFsS3m2b4TvfIlkyqCjc4PhfS=>		MYfUbIUh[2:vcH;1coQhf2G\|IHX2ZYx2[XSnZDDmc5IhfGinIHP5eI91d3irY3n0fUBi\2GrboP0JIh2dWGwIFPINUApd3[jcnnhckkhfHWvb4KgZ4VtdCCuaX7ld{whUUN3ME20NEBvVQ>?	MX2xNFY6QDR2NB?=
human HT-29 (colon) tumor cell	NXWyNZdHS3m2b4TvfIlkyqCjc4PhfS=>		M2rUOnRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliKHPvcI9vMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P	MkPKNVA3QTh2NES=
human A549 cells	NWXQPIlmS3m2b4TvfIlkyqCjc4PhfS=>	NIPpfVQ1QCCq	MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;NECgcm0>	M3fkUlI2OjV7NUG1
human ME-180 cell	MoLQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MWjJcohq[mm2aX;uJI9nKGi3bXHuJG1GNTF6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUSwMlEyKG6P	NVjZXHdDW0GQR1XS
human CAL-27 cell	MlvLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MnrDTY5pcWKrdHnvckBw\iCqdX3hckBESUxvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU4yQCCwTR?=	NGj0VJZUSU6JRWK=
human A431 cell	NYrnWHRFT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		M3TPUmlvcGmkaYTpc44hd2ZiaIXtZY4hSTR\|MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUSzMlc4KG6P	NULCVVQ5W0GQR1XS
human SW954 cell	MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVTMNnZqUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjlzIH7N	NYLvVnB{W0GQR1XS
human CAL-39 cell	M{TWPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MkDITY5pcWKrdHnvckBw\iCqdX3hckBESUxvM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok41QSCwTR?=	M2\tcHNCVkeHUh?=
human LU-134-A cell	NFPQd4xIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NET4UJdKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwN{Kgcm0>	MnfKV2FPT0WU
human DU-4475 cell	MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		M3f1VGlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvNES3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjR5IH7N	NX\ydWNuW0GQR1XS
P388 cells (P388/S) cells	NGnJV3ZHfW6ldHnvckBie3OjeR?=		NUTVeFFSTX[jbIXheIlwdiCxZjDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4Sg[JJ2\yC\|ZX7zbZRqfmViUEO4PEBk\WyuczCoVFM5QC:VKTDj[YxteyxiSVO1NF01QCCwTR?=	MXS4OVQ1OTh\|
human DEL cell	M3LaR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NI\LS5BKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUS4MlM6KG6P	NGDue3BUSU6JRWK=
human HGC-27 cell	M1TVV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7		MoC3TY5pcWKrdHnvckBw\iCqdX3hckBJT0NvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PU4zQSCwTR?=	M4DoWnNCVkeHUh?=
human RH-1 cell	MmK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		NYny[\|E6UW6qaXLpeIlwdiCxZjDoeY1idiCUSD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvPTdibl2=	MXjTRW5ITVJ?
HL-60 cells	MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MYnJcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIIfhd{B{fHWmaXXkJIlvKGi3bXHuJJBzd227ZXzvZ5l1cWNibHX1b4VucWNiKFjMMVYxMSClZXzsd{whUUN3ME21NEBvVQ>?	M4Gwc\|g4ODlzMUG=
human A2780 (ovarian) tumor cell	NUL5bZE{S3m2b4TvfIlkyqCjc4PhfS=>		MX;UbIUh[2:vcH;1coQhf2G\|IHX2ZYx2[XSnZDDmc5IhfGinIHP5eI91d3irY3n0fUBi\2GrboP0JIh2dWGwIFGyO\|gxKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVUxKG6P	M1PJS\|ExPjl6NES0
human SK-MES-1 cell	NYPQbZVxT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MmHqTY5pcWKrdHnvckBw\iCqdX3hckBUUy2PRWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUyNjF{IH7N	NW\hWI5KW0GQR1XS
human MEL-JUSO cell	NFHW[Y9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		M3z0SGlvcGmkaYTpc44hd2ZiaIXtZY4hVUWOLVrVV28h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02OS5{NTDuUS=>	M3[yRXNCVkeHUh?=
human VA-ES-BJ cell	M3PpdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NUO2T4JGUW6qaXLpeIlwdiCxZjDoeY1idiCYQT3FV{1DUiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxRTV{LkG2JI5O	NF3EN2JUSU6JRWK=
human EW-13 cell	MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MmjTTY5pcWKrdHnvckBw\iCqdX3hckBGXy1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUWyMlUyKG6P	Mlz1V2FPT0WU
human Ca-Ski cell	NH3POYRIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NFTINXZKdmirYnn0bY9vKG:oIHj1cYFvKEOjLWPrbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU{Njd3IH7N	NHnEU5ZUSU6JRWK=
human LXF-289 cell	NWHReXBYT3Kxd4ToJIlvcGmkaYTpc44h[XO\|YYm=		MkfGTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVUvOzdibl2=	MVvTRW5ITVJ?
human IM-9 cell	MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		NVrPc4o6UW6qaXLpeIlwdiCxZjDoeY1idiCLTT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVYvOjJibl2=	NXyzNmRCW0GQR1XS
human HCE-4 cell	M4\FSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		NU\XV282UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1WtOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU4Njl2IH7N	M2PPZ3NCVkeHUh?=
human TYK-nu cell	MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MUTJcohq[mm2aX;uJI9nKGi3bXHuJHR[Uy2wdTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyPUW4MlczKG6P	NUPxb\|IxW0GQR1XS
human NCI-H748 cell	Ml:yS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		MofsTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEe0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU6NjV2IH7N	M2fUXnNCVkeHUh?=
human ABC-1 cell	MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MWXJcohq[mm2aX;uJI9nKGi3bXHuJGFDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTB;NkGuNkBvVQ>?	MlnBV2FPT0WU
human CCRF-CEM cell	M2DhSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7		M1LZS2lvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03OS54ODDuUS=>	NH[1N49USU6JRWK=
human EW-3 cell	NH7pco9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NWrjVFUxUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlEvQTVibl2=	NFnzbYdUSU6JRWK=
human NCI-H2342 cell	Mk\JS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl?		Mm\nTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKzOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03Oi53MTDuUS=>	NEXSU\|dUSU6JRWK=
human CNS cancer cells	MlHxR5l1d3SxeHnjxsBie3OjeR?=		Mn36R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR25UKGOjbnPldkBk\WyuczygS2k2OD14NDDuUS=>	MV2xNVQ4OzRzOB?=
human SK-PN-DW cell	NES0SoVIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		MVXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNVCQLVTXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OlMvPzZibl2=	MYHTRW5ITVJ?
human EB2 cell	MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>?		MoLmTY5pcWKrdHnvckBw\iCqdX3hckBGSjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygbYM2OD14NT6zOkBvVQ>?	NUD6NIdnW0GQR1XS
human HUT78 cells	NUnQRm1wWHKxbHnm[ZJifGmxbjDhd5NigQ>?	NYjk[GNpPDhiaB?=	NWXvfm1GSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWXQ4QCClZXzsd{Bi\nSncjC0PEBpenNiYomgdoV{[Xq3cnnuJJJm\HWldHnvckBie3OjeTygbYM2OD14NjDuUS=>	NIHBPGYzPjV2MUW4Oy=>
human colon cancer cell line HCT15	M3\SdmN6fG:2b4jpZ:Kh[XO\|YYm=	NIfrNJA4OiCq	MU\JckB3cXS{bzDjfZRwfG:6aXOgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJGhEXDF3IHHmeIVzKDd{IHjyJI9nKGS{dXeg[Zhxd3O3cnWg[IV1\XKvaX7l[EBjgSC2aHWgV3JDKGG\|c3H5MEBKSzVyPUewJI5O	MX2xOFk5ODZ5Mh?=
human HCT8 cells	NIfnNW1EgXSxdH;4bYPDqGG\|c3H5	NHfE[Fg4OiCq	NIjHVmVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1R6IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9PFMhdk1?	NF;xfHEyQDh2NUS0NS=>
human THP1 cells	MVrDfZRwfG:6aXRCpIF{e2G7	MnvCOFghcA>?	MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDUTHAyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTB;MD6xJO69VQ>?	MV[yOVI2QTVzNR?=
human PC3 cells	NWfZTmFLWHKxbHnm[ZJifGmxbjDhd5NigQ>?	M1\V[FczKGh?	MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhfHK7cHHuJIJtfWViZYjjcJV{cW:wIHHzd4F6NCCHQ{WwQVAvOTRizszN	NVe1T2lJOTl4N{S5NFU>

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting. p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; PubMed: 24901052 Cell Death Dis LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane. Beclin 1 / p62 / ATG5; PubMed: 29142609 Oncol Lett (A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; PubMed: 28553347 Neural Regen Res (A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).	24901052 29142609 28553347

In vivo

As the clinical first choice in superficial bladder tumors, in a rat bladder tumor model, Mitomycin C (400 μM) significantly prevents intravesical tumor growth. ^[4]

Protocol

Animal Research:^[4]	- Collapse Animal Models: Rat bladder tumor model Formulation: saline Dosages: 400 μM Administration: Intravesical treatment (Only for Reference)

References

[4] Jankun J, et al. Int J Oncol. 2014, 44(1), 147-152.

- Collapse

Solubility (25°C)

In vitro	DMSO	66 mg/mL (197.38 mM)
	Water	Insoluble
	Ethanol	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download Mitomycin C SDF

Molecular Weight	334.37
Formula	C₁₅H₁₈N₄O₅
CAS No.	50-07-7
Storage	3 years -20°C powder
Storage	2 years -80°C in solvent
Synonyms	N/A

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

NCT Number	Recruitment	interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02199327	Completed	Drug: Mitomycin C\|Drug: Interferon Alfa-2b	Conjunctival Intraepithelial Neoplasia\|Corneal Intraepithelial Neoplasia	Coordinación de Investigación en Salud Mexico\|Instituto Mexicano del Seguro Social\|University of Guadalajara	May 2014	Phase 4
NCT02015650	Unknown status	Drug: Cetuximab\|Drug: Mitomycin-C/ 5-Fluorouracil	Head and Neck Neoplasms	Medical University Innsbruck	April 2014	Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Tel: +1-832-582-8158 Ext:3

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DNA/RNA Synthesis Signaling Pathway Map

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Mitomycin C

Cited by 16 Publications

1 Customer Review

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Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Dilution Calculator

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products

Choose Your Country or Region

By Signaling Pathways

By product type

Mitomycin C

Cited by 16 Publications

1 Customer Review

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download Mitomycin C SDF

Bio Calculators

Molarity Calculator

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Dilution Calculator

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2019-10-14)

Tech Support

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)