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IWP-2 WNT Pathway inhibitor

Name: IWP-2
Brand: Selleck Chemicals
SKU: S7085
Availability: InStock
Rating: 5 (140 reviews)

Cat.No.S7085

IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.

Chemical Structure

Molecular Weight: 466.6

Related Targets	JAK TGF-beta/Smad ERK GSK-3 ROCK Hedgehog/Smoothened PKA Secretase STAT Casein Kinase
Other Wnt/beta-catenin Inhibitors	IWR-1-endo Tegatrabetan (BC-2059) Isoquercitrin ICG-001 SKL2001 BML-284 Hydrochloride (Wnt agonist 1, AMBMP) PNU-74654 LF3 Salinomycin (Procoxacin) FH535

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Working Concentrations for Animal Model Treatment

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IWP-2 WNT Pathway inhibitor

Molecular Weight: 466.6

Working Concentrations for Cell Culture Treatment

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Working Concentrations for Animal Model Treatment

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