Clevidipine Butyrate

For research use only.

Catalog No.S2080

Clevidipine Butyrate Chemical Structure

CAS No. 167221-71-8

Clevidipine Butyrate is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure.

Size Price Stock Quantity  
10mM (1mL in DMSO) EUR 88 In stock
EUR 68 In stock
EUR 461 In stock
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Biological Activity

Description Clevidipine Butyrate is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure.
Targets
Calcium channel [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 91 mg/mL (199.42 mM)
Ethanol 3 mg/mL (6.57 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 456.32
Formula

C21H23Cl2NO6

CAS No. 167221-71-8
Storage powder
in solvent
Synonyms N/A
Smiles CCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04143503 Completed -- Critical Illness Fresenius Kabi|IQVIA Commercial GmbH & Co. OHG November 5 2019 --
NCT02011321 Unknown status Drug: clevidipine Subarachnoid Hemorrhage|Cerebral Aneurysm|Vasospasm Intracranial Henry Ford Health System March 2014 Phase 2
NCT01938547 Suspended Drug: clevidipine Pediatric Perioperative Blood Pressure Management Chiesi Farmaceutici S.p.A. March 2014 Phase 4
NCT01480531 Withdrawn Drug: Clevidipine Aorta Aneurysm|Dissection of Aorta Duke University|The Medicines Company December 2011 Not Applicable
NCT01910532 Withdrawn Drug: Clevidipine Hypertension Mario Ammirati|Ohio State University April 2010 Phase 4
NCT01033370 Terminated Drug: clevidipine. Aortic Aneurysm|Aortic Disease Asma Zainab M.D.|The Medicines Company|The Methodist Hospital System November 2009 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Calcium Channel Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID