Name: Rutin
Brand: Selleck Chemicals
SKU: S2350
Availability: InStock
Rating: 5 (13 reviews)

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Quality Control

Batch: Purity: 98.64%

98.64

Related Targets	PD-1/PD-L1 CXCR STING AhR Immunology & Inflammation related CD markers Interleukins Anti-infection Antioxidant COX
Other ADC Cytotoxin Inhibitors	Triptolide SN-38 Luteolin (+)-Bicuculline Artemisinin BHQ Pinocembrin Luteoloside Psoralen Lappaconite HBr

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (163.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	5.000mg/ml (8.19mM)	Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.700mg/ml (1.15mM)	Taking the 1 mL working solution as an example, add 50 μL of 14 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	610.52	Formula	C₂₇H₃₀O₁₆	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	153-18-4	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Rutoside			SMILES	CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

In vitro	Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human. This compound inhibits platelet aggregation as well as decreases capillary permeability, making the blood thinner and improving circulation. Recent studies show it could help prevent blood clots, so could be used to treat patients at risk of heart attacks and strokes.
In vivo	LD50: Mice 650mg/kg (i.p.)
References	[1] https://pubmed.ncbi.nlm.nih.gov/18410117/ [2] https://pubmed.ncbi.nlm.nih.gov/7482952/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2025-12-30)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07310407	NOT_YET_RECRUITING	NAFLD	Ain Shams University	2026-01-01	PHASE2
NCT06718452	NOT_YET_RECRUITING	Tinnitus; Neuroinflammation	University of Campania Luigi Vanvitelli	2026-04-20
NCT07689214	RECRUITING	Diabete Type 2	University of Roma La Sapienza	2024-07-17
NCT07564999	ENROLLING_BY_INVITATION	The Aim is to Strengthen Disaster Preparedness Knowledge and Skills Through Peer Interaction	Selcuk University	2026-05-15
NCT06916494	RECRUITING	Muscle Invasive Bladder Cancer	First Affiliated Hospital of Chongqing Medical University	2025-05-01	PHASE1
NCT06705777	COMPLETED	Haemorrhoidal Disease	Fundação Educacional Serra dos Órgãos	2024-09-01	PHASE4

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Rutin ADC Cytotoxin chemical

Chemical Structure

Molecular Weight: 610.52