Active Pharmaceutical Ingredients

Catalog No. Product Name Information
S1794 Fenofibrate (NSC-281319) Fenofibrate (NSC-281319) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.
S2073 Mitiglinide Calcium Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.
S3113 Pyridoxine HCl Pyridoxine HCl (Vitamin B6) is a form of vitamin B6.
S1213 Nelarabine Nelarabine (506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
S1920 Haloperidol Haloperidol (Haldol) is an antipsychotic and butyrophenone.
S2129 Fudosteine Fudosteine is a cysteine derivative and a MUC5AC mucin hypersecretion inhibitor, used as a muco-active agent with indications for chronic respiratory diseases.
S2074 Mecarbinate Mecarbinate (Dimecarbin) is a chemical intermediate of arbidol hydrochloride.
S3138 Methylthiouracil Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
S1908 Flutamide Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.
S2075 Rosiglitazone (BRL-49653) HCl Rosiglitazone HCl (BRL-49653) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
S1763 Quetiapine (ICI-204636) fumarate Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.
S2076 Lisinopril dihydrate Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.
S1751 Gadodiamide Hydrate Gadodiamide Hydrate, a nonionic Gd3+ chelate, is frequently injected i.v. into magnetic resonance imaging (MRI) to enhance contrast.
S1998 D-Cycloserine D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.
S2077 Atorvastatin Calcium Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin Calcium induces apoptosis and autophagy.
S3165 Abacavir sulfate Abacavir (1592U89) is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
S1972 Tamoxifen (ICI 46474) Citrate Tamoxifen Citrate (ICI 46474) is a selective estrogen receptor modulator (SERM). Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis and autophagy.
S2015 Suplatast Tosylate Suplatast Tosylate (IPD-1151T, Suplatast Tosilate) is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.
S1828 Proparacaine HCl Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.
S3167 Altrenogest Altrenogest (A35957, RU2267) is a progestogen structurally related to veterinary steroid trenbolone.