Oxiglutatione

Catalog No.S3743 Synonyms: Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)

For research use only.

Oxiglutatione (Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)) is the oxidized disulfide form of glutathione (GSH) with potential protective activity.

Oxiglutatione Chemical Structure

CAS No. 27025-41-8

Purity & Quality Control

Related Other Products

Biological Activity

Description Oxiglutatione (Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)) is the oxidized disulfide form of glutathione (GSH) with potential protective activity.

Protocol (from reference)

Solubility (25°C)

In vitro

Water 100 mg/mL
(163.23 mM)
DMSO 7 mg/mL
(11.42 mM)
Ethanol Insoluble

Chemical Information

Molecular Weight 612.63
Formula

C20H32N6O12S2

CAS No. 27025-41-8
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04887311 Not yet recruiting Drug: MBM-01 Ataxia Telangiectasia Louis-Bar|Ataxia Telangiectasia in Children|Ataxia Telangiectasia Matrix Biomed Inc.|The University of Texas Health Science Center Houston July 2021 Phase 2
NCT04912947 Completed Dietary Supplement: Immusystem|Other: Placebo Oxidative Stress Complife Italia Srl|Macrofarm Srl|Icim International Srl October 30 2020 Not Applicable
NCT04154982 Recruiting Drug: Acetyl cysteine Cardiac Arrhythmia Centro Cardiologico Monzino|Ministry of Health Italy September 2 2020 Phase 2

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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