Promazine hydrochloride

Catalog No.S5428 Synonyms: Romtiazin hydrochloride, Sinophenin hydrochloride

For research use only.

Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.

Promazine hydrochloride Chemical Structure

CAS No. 53-60-1

Purity & Quality Control

Choose Selective Dopamine Receptor Inhibitors

Other Dopamine Receptor Products

Biological Activity

Description Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 64 mg/mL
(199.45 mM)


Chemical Information

Molecular Weight 320.88
Formula

C17H20N2S.HCl

CAS No. 53-60-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Promazine hydrochloride | Promazine hydrochloride ic50 | Promazine hydrochloride price | Promazine hydrochloride cost | Promazine hydrochloride solubility dmso | Promazine hydrochloride purchase | Promazine hydrochloride manufacturer | Promazine hydrochloride research buy | Promazine hydrochloride order | Promazine hydrochloride mouse | Promazine hydrochloride chemical structure | Promazine hydrochloride mw | Promazine hydrochloride molecular weight | Promazine hydrochloride datasheet | Promazine hydrochloride supplier | Promazine hydrochloride in vitro | Promazine hydrochloride cell line | Promazine hydrochloride concentration | Promazine hydrochloride nmr