Catalog No.S2284 Synonyms: Colchineos, Colchisol, Colcin

Colchicine Chemical Structure

Molecular Weight(MW): 399.44

Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM.

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Choose Selective Microtubule Associated Inhibitors

Biological Activity

Description Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM.



Solubility (25°C)

In vitro DMSO 80 mg/mL (200.28 mM)
Water 80 mg/mL (200.28 mM)
Ethanol 80 mg/mL (200.28 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 399.44


CAS No. 64-86-8
Storage powder
in solvent
Synonyms Colchineos, Colchisol, Colcin

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03927677 Not yet recruiting Drug: Xanthine Oxidase Inhibitor Gout|Hyperuricemia LG Chem October 30 2019 Phase 1
NCT03933007 Not yet recruiting Drug: Colchicine|Drug: midazolam|Drug: fexofenadine Gout Flare Assistance Publique - Hôpitaux de Paris May 1 2019 Phase 4
NCT03575572 Recruiting Drug: Colchicine Single-ventricle|Heart Diseases University of Michigan August 29 2018 Phase 2|Phase 3
NCT03210610 Recruiting Diagnostic Test: colchicine level measurement FMF|Colchicine Resistance|Colchicine Toxicity Sheba Medical Center October 19 2017 --
NCT03015831 Recruiting Drug: Colchicine|Drug: Placebo Oral Tablet Atrial Fibrillation|Cardiac Surgery|Colchicine Adverse Reaction Jordan Collaborating Cardiology Group October 2 2017 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Microtubule Associated Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID