For research use only.

Catalog No.S2284 Synonyms: Colchineos, Colchisol, Colcin

7 publications

Colchicine Chemical Structure

Molecular Weight(MW): 399.44

Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM.

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Choose Selective Microtubule Associated Inhibitors

Biological Activity

Description Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM.



Solubility (25°C)

In vitro DMSO 80 mg/mL (200.28 mM)
Water 80 mg/mL (200.28 mM)
Ethanol 80 mg/mL (200.28 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 399.44


CAS No. 64-86-8
Storage powder
in solvent
Synonyms Colchineos, Colchisol, Colcin
Smiles COC1=CC=C2C(=CC1=O)C(CCC3=C2C(=C(OC)C(=C3)OC)OC)NC(C)=O

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Molarity Calculator

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Dilution Calculator

Dilution Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04375202 Recruiting Drug: Colchicine 1 MG Oral Tablet COVID-19 University Of Perugia April 18 2020 Phase 2
NCT04377321 Completed Drug: Colchicine Tablets Treatment Adherence Ministry of Health and Population Egypt October 10 2019 --
NCT03927677 Not yet recruiting Drug: Xanthine Oxidase Inhibitor Gout|Hyperuricemia LG Chem October 30 2019 Phase 1
NCT03933007 Recruiting Drug: Colchicine|Drug: midazolam|Drug: fexofenadine Gout Flare Assistance Publique - Hôpitaux de Paris September 10 2019 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Microtubule Associated Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID