STING

Inhibitory Selectivity

STING Products

New STING Products
Catalog No. Information Product Use Citations Product Validations
S6667New

STING inhibitor C-178

C-178 is a covalent inhibitor of STING,covalently bind to Cys91.

S6575New

C-176 STING inhibitor

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING, a central signaling component of the intracellular DNA sensing pathway.

S7904New

2',3'-cGAMP

2',3'-cGAMP is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). The binding affinity of 2 ’, 3’-cGAMP to STING is 3.79 nM (Kd value).

S7905New

3',3'-cGAMP

3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

S6652New

H-151

H-151 is a highly potent and covalent antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo.

S8796New

diABZI STING agonist(compound 3)

STING agonist 1 (compound 3) is a potent non-nucleotide STING agonist and has tremendous potential to improve treatment of cancer in humans.

Catalog No. Information Product Use Citations Product Validations
S6667New

STING inhibitor C-178

C-178 is a covalent inhibitor of STING,covalently bind to Cys91.

S6575New

C-176 STING inhibitor

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING, a central signaling component of the intracellular DNA sensing pathway.

Catalog No. Information Product Use Citations Product Validations
S7904New

2',3'-cGAMP

2',3'-cGAMP is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). The binding affinity of 2 ’, 3’-cGAMP to STING is 3.79 nM (Kd value).

S7905New

3',3'-cGAMP

3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

Catalog No. Information Product Use Citations Product Validations
S6652New

H-151

H-151 is a highly potent and covalent antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo.

Catalog No. Information Product Use Citations Product Validations
S8796New

diABZI STING agonist(compound 3)

STING agonist 1 (compound 3) is a potent non-nucleotide STING agonist and has tremendous potential to improve treatment of cancer in humans.

Tags: STING antagonist | STING inhibitor | STING agonist