3',3'-cGAMP

For research use only.

Catalog No.S7905 Synonyms: 3',3'-cyclic GMP-AMP

3',3'-cGAMP Chemical Structure

Molecular Weight(MW): 672.4

3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

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USD 337

Purity & Quality Control

Choose Selective STING Inhibitors

Biological Activity

Description 3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight 672.4
Formula

C20H24N10O13 P2·xNa+

CAS No. 849214-04-6(freeacid)
Storage powder
in solvent
Synonyms 3',3'-cyclic GMP-AMP

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01199250 Not yet recruiting Other: Laboratory Biomarker Analysis Lynch Syndrome|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer Gynecologic Oncology Group|National Cancer Institute (NCI) January 2100 --
NCT03643887 Not yet recruiting Drug: FMT Capsule DE|Drug: Placebo oral capsule Clostridium Difficile Infection University of Wisconsin Madison September 1 2022 Phase 2
NCT03737617 Suspended Drug: Cuvitru 20 % Injectable Solution Bronchiectasis|Immunoglobulin Subclass Deficiency University of Edinburgh|NHS Lothian August 5 2022 Phase 4
NCT04077866 Not yet recruiting Drug: Temozolomide|Biological: B7-H3 CAR-T Recurrent Glioblastoma|Refractory Glioblastoma Second Affiliated Hospital School of Medicine Zhejiang University|Ningbo Yinzhou People''s Hospital|Huzhou Central Hospital|BoYuan RunSheng Pharma (Hangzhou) Co. Ltd. May 1 2022 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID