• Estrogen receptor
  • Progesterone receptor
  • ERR

Progesterone receptor Selective Inhibitors | Agonists | Antagonists | Chemicals | Modulators

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2606 Mifepristone (RU486) Mifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1. Selective Progesterone receptor, IC50: 0.2 nM
S1304 Megestrol Acetate Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite. Selective
S2567 Medroxyprogesterone acetate (NSC-26386) Medroxyprogesterone acetate (MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding. Selective
S3160 Ethynodiol diacetate Ethynodiol diacetate (8080 CB) is one of the first synthetic progestogens used in contraceptive pills. Selective
S1727 Levonorgestrel Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation. Selective
S4097 Dydrogesterone Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus. Selective
S1914 Pregnenolone Pregnenolone is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries. Selective
S1705 Progesterone (NSC 9704) Progesterone (NSC 9704, NSC 64377, Pregn-4-ene-3,20-dione) is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor. Selective
S1377 Drospirenone Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone. Selective
S3081 Ulipristal Acetate (CDB 2914) Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. Selective
S3167 Altrenogest Altrenogest (A35957, RU2267) is a progestogen structurally related to veterinary steroid trenbolone. Selective
s1251 Dienogest Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis. Selective
S2611 Ethisterone Ethisterone is a progestogen hormone being considered to treat prostate cancer. Selective