Catalog No.S3081 Synonyms: CDB-2914

Ulipristal Chemical Structure

Molecular Weight(MW): 475.62

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.

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In DMSO USD 320 In stock
USD 170 In stock
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Biological Activity

Description Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
Progesterone receptor [1]
In vitro

Ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to theglucocorticoid receptor, but has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors.[1]

In vivo Based on clinical trials, ulipristal acetate seems to be a reasonably tolerable and effective method of emergency contraception when used within 120 hours of intercourse. Ulipristal acetate is at least as effective as LNG when used within the first 72 hours after unprotected intercourse. However, ulipristal acetate may be more effective than LNG when used between 72 to 120 hours after unprotected intercourse, extending the window of opportunity for emergency contraception. [2][3]


Solubility (25°C)

In vitro DMSO 83 mg/mL (174.5 mM)
Ethanol 14 mg/mL (29.43 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 475.62


CAS No. 126784-99-4
Storage powder
in solvent
Synonyms CDB-2914

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03349190 Completed Drug: ULIPRISTAL ACETATE Infertility Female|Fibroid Uterus ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO|Gedeon Richter Plc. December 29 2017 --
NCT03342859 Active not recruiting Drug: Vilaprisan BAY1002670|Drug: Ulipristal Leiomyoma Bayer November 16 2017 Phase 1
NCT03118297 Completed Drug: Ulipristal Acetate|Drug: Placebo oral capsule Contraception|Bleeding Washington University School of Medicine May 1 2017 Phase 3
NCT03156127 Withdrawn Drug: BR-UPS 5 mg tablet Inisia 5 mg tablet Uterine Myoma Boryung Pharmaceutical Co. Ltd May 19 2017 Phase 1
NCT02408770 Active not recruiting Drug: ulipristal acetate Breast Cancer Manchester University NHS Foundation Trust|University of Manchester March 2016 Phase 2

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Estrogen/progestogen Receptor Signaling Pathway Map

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