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Aminothiazole Bacterial inhibitor

Cat.No.S4198

Aminothiazole(2-Aminothiazole,2-Thiazolylamine) can be used as a thyroid inhibitor and it has antibacterial activity.
Aminothiazole Bacterial inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 100.14

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability Specificity

Quality Control

Batch: S419801 DMSO]20 mg/mL]false]Water]20 mg/mL]false]Ethanol]20 mg/mL]false Purity: 99.76%
99.76

Chemical Information, Storage & Stability

Molecular Weight 100.14 Formula

C3H4N2S

 Storage (From the date of receipt)
CAS No. 96-50-4 Download SDF Storage of Stock Solutions

Synonyms 2-Aminothiazole,2-Thiazolylamine Smiles C1=CSC(=N1)N

Solubility

In vitro
Batch:

DMSO : 20 mg/mL (199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 20 mg/mL

Ethanol : 20 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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%
% Tween 80
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro

An aminothiazole compound has fungistatic activity against Histoplasma yeast at micromolar concentrations, and has the greatest selectivity for yeast
In vivo
An aminothiazole compound derived from dendrodoine can protect mouse myocardium against damage and one of the possible reasons behind this protective effect can be attributed to its antioxidant property.
References

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