Ornidazole

Catalog No.S3121 Synonyms: Ro7-0207, NSC 95075

For research use only.

Ornidazole (Ro7-0207, NSC 95075) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.

Ornidazole Chemical Structure

CAS No. 16773-42-5

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Ornidazole (Ro7-0207, NSC 95075) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
In vitro

Ornidazole is a 5-nitroimidazole derivative active against protozoa and anaerobic bacteria. It is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 44 mg/mL
(200.33 mM)
Water 2 mg/mL
(9.1 mM)
Ethanol '44 mg/mL

Chemical Information

Molecular Weight 219.63
Formula

C7H10ClN3O3

CAS No. 16773-42-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]

In vivo Formulation Calculator (Clear solution)

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% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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