For research use only.
Catalog No.S0723 Synonyms: BRL-15,572
CAS No. 734517-40-9
BRL 15572 is selective antagonist of 5-HT1D with around 60× selectivity over other related receptors. BRL 15572 is a useful tool for the differentiation between human 5-HT1B and 5-HT1D receptors in functional studies.
Purity & Quality Control
|Description||BRL 15572 is selective antagonist of 5-HT1D with around 60× selectivity over other related receptors. BRL 15572 is a useful tool for the differentiation between human 5-HT1B and 5-HT1D receptors in functional studies.|
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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