5-HT5 Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1283 Asenapine

Asenapine is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.

Pan 5-HT5A, pKi: 8.84
S1615 Risperidone

Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.

Pan 5-HT5A, Ki: 206 nM; 5-HT5A, Ki: 206 nM