Catalog No.S4244 Synonyms: 5-HT HCl
Molecular Weight(MW): 212.68
Serotonin HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
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Choose Selective 5-HT Receptor Inhibitors
|Description||Serotonin HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.|
Serotonin stimulates acid–base transport by the anterior stomach region of the midgut in vitro. The function of this stimulation is assumed to be maintenance of optimal conditions for digestion and absorption of nutrients rather than regulation of hemolymph acid–base homeostasis. 
|In vivo||The role of serotonin in the regulation of larval Aedes aegypti hemolymph composition is investigated in vivo using two reuptake inhibitors (SSRIs), alaproclate HCl and 6-nitroquipazine maleate, and the receptor antagonist methiothepin mesylate. |
|In vitro||DMSO||42 mg/mL (197.47 mM)|
|Water||42 mg/mL (197.47 mM)|
|Ethanol||2 mg/mL (9.4 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03576053||Recruiting||Itch|Thermal Stimulation|Histamine|Cowhage|Serotonine||Aalborg University||July 1 2018||Not Applicable|
|NCT03471819||Not yet recruiting||Dermatologic Disease||Assiut University||April 1 2018||--|
|NCT03222570||Recruiting||Depressive Disorder||University of Minnesota - Clinical and Translational Science Institute||February 26 2018||Phase 2|
|NCT03321526||Active not recruiting||Depressive Disorder Major||Janssen Research & Development LLC||December 12 2017||Phase 2|
|NCT03364075||Terminated||Low Back Pain||Mark Ware|McGill University Health Center||September 1 2017||Phase 2|
|NCT02865642||Recruiting||Stroke||University Hospital Inselspital Berne|Cantonal Hospital of St. Gallen||August 2016||Phase 2|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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