For research use only.

Catalog No.S3133

Sulfamethazine Chemical Structure

CAS No. 57-68-1

Sulfamethazine is a sulfonamide antibacterial.

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Sulfamethazine is a sulfonamide antibacterial.
In vitro

Sulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis.


Solubility (25°C)

In vitro DMSO 56 mg/mL (201.2 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 278.33


CAS No. 57-68-1
Storage powder
in solvent
Synonyms N/A
Smiles CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID