Sulfamerazine

Catalog No.S3132 Synonyms: RP 2632

For research use only.

Sulfamerazine (RP 2632) is a sulfonamide antibacterial.

Sulfamerazine Chemical Structure

CAS No. 127-79-7

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Sulfamerazine (RP 2632) is a sulfonamide antibacterial.
In vitro

Sulfamerazine exhibits biexponential decay in water and triexponential decay in cyclodextrins solutions. Sulfamerazine shows remarkably upfield shift in the complexes suggested that the aniline ring deeply encapsulated in the CD cavity. [1]

In vivo Sulfamerazine results in a marked evolution in the shape of the concentration-time curves in function of age, strongly suggesting a defective absorption rate in the first weeks after birth in lambs. [2] Sulfamerazine has a significantly beneficial effect on life span of rats and apparently increases that of male hamsters, and all rats fed sulfamerazine attains higher maximum weights than their controls. [3]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 264.3
Formula

C11H12N4O2S

CAS No. 127-79-7
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=NC(=NC=C1)NS(=O)(=O)C2=CC=C(C=C2)N

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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