Pyrazinamide

Catalog No.S1762 Synonyms: Pyrazinoic Acid Amide

For research use only.

Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.

Pyrazinamide Chemical Structure

CAS No. 98-96-4

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 123.11
Formula

C5H5N3O

CAS No. 98-96-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CN=C(C=N1)C(=O)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05329415 Recruiting Diagnostic Test: TB Drug Levels Tuberculosis|Diabetes Mellitus London North West Healthcare NHS Trust February 1 2022 --
NCT04972903 Not yet recruiting -- Tuberculosis|Pulmonary Institut National de la Santé Et de la Recherche Médicale France|National Agency for Research on AIDS and Viral Hepatitis (ANRS) August 2021 --
NCT04239326 Recruiting Diagnostic Test: targeted Next Generation Sequencing (tNGS) Tuberculosis Multidrug-Resistant Foundation for Innovative New Diagnostics Switzerland April 16 2021 --
NCT03800381 Recruiting Other: Observational PK study Tuberculosis|Human Immunodeficiency Virus|Coinfection University of Florida|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) January 28 2019 --
NCT05283967 Recruiting Diagnostic Test: urine colorimetric assay Tuberculosis University of Virginia|Rutgers The State University of New Jersey|University of Florida January 1 2019 --

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Pyrazinamide | Pyrazinamide ic50 | Pyrazinamide price | Pyrazinamide cost | Pyrazinamide solubility dmso | Pyrazinamide purchase | Pyrazinamide manufacturer | Pyrazinamide research buy | Pyrazinamide order | Pyrazinamide mouse | Pyrazinamide chemical structure | Pyrazinamide mw | Pyrazinamide molecular weight | Pyrazinamide datasheet | Pyrazinamide supplier | Pyrazinamide in vitro | Pyrazinamide cell line | Pyrazinamide concentration | Pyrazinamide nmr