Home Invivo Functional Antibodies Immunology & Inflammation Immunology & Inflammation related Anti-mouse TIM-3 (CD366)-InVivo
For research use only. Not for use in humans.

Anti-mouse TIM-3 (CD366)-InVivo

Clone No.：B8.2C12

Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNγ production and Th1 cell proliferation.

Anti-mouse TIM-3 (CD366)-InVivo

Click to purchase the isotype control of Anti-mouse TIM-3 (CD366)-InVivo

1 Citation

The Nobel Prize

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: Purity: 99% Protein concentration: 5.69 mg/ml Endotoxin Level: ＜1EU/mg
99

Product Details

Molecular Weight 150 kDa
Clone B8.2C12
Isotype Rat IgG2a, κ
Application Anti-mouse TIM-3 (CD366)-InVivo
Source CHO
Purification Protein G
Sterility 0.2 μM filtered
Formulation PBS, pH 7.0 Contains no stabilizers or preservatives
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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