Anti-mouse CD40L (CD154)-InVivo Immunology & Inflammation related inhibitor

The MR-1 monoclonal antibody reacts with mouse CD154 also known as CD40 ligand. The MR-1 monoclonal antibody has been reported to inhibit in vitro activation of B lymphocytes by blocking the binding of CD154 with CD40 on T helper cells as well as inhibit the formation of germinal centers and disrupt antigen-specific T cell responses. Additionally, the MR-1 antibody blocks interactions of T cells and antigen-presenting cells in vitro and blocks the development of experimental autoimmune disease in vivo.

Click to purchase the isotype control of Anti-mouse CD40L (CD154)-InVivo

Quality Control

Batch: Purity: 99% Protein concentration: 5.68 mg/mL Endotoxin Level: ＜1EU/mg

99

Product Details

Molecular Weight	150 kDa
Clone	MR-1
Immunogen	Activated mouse Th1 clone D1.6
Isotype	Armenian Hamster IgG
Application	in vivo/vitro blocking of CD40/CD40L,WB
Purification	protein A
Sterility	0.2 μM filtered
Formulation	PBS buffer, pH 7.0
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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