Anti-mouse CD40L (CD154)-InVivo
The MR-1 monoclonal antibody reacts with mouse CD154 also known as CD40 ligand. The MR-1 monoclonal antibody has been reported to inhibit in vitro activation of B lymphocytes by blocking the binding of CD154 with CD40 on T helper cells as well as inhibit the formation of germinal centers and disrupt antigen-specific T cell responses. Additionally, the MR-1 antibody blocks interactions of T cells and antigen-presenting cells in vitro and blocks the development of experimental autoimmune disease in vivo.
|Molecular Weight||150 kDa|
|Immunogen||Activated mouse Th1 clone D1.6|
|Formulation||PBS buffer, pH 7.0|
|Isotype||Armenian Hamster IgG|
|Application||in vivo/vitro blocking of CD40/CD40L,WB|
|Storage||Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles|
|Sterility||0.2 μM filtered|
If you have any other enquiries, please leave a message.