The 145-2C11 monoclonal antibody reacts with mouse CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The 145-2C11 antibody has been shown to induce T lymphocyte activation, proliferation, and apoptosis in vitro via binding and stimulating the TCR. When used in vivo the antibody is reported to produce T cell activation, anergy, or death.
|Molecular Weight||150 kDa|
|Immunogen||Mouse BM10-37 cytotoxic T cells|
|Formulation||PBS buffer, pH 7.0|
|Isotype||Armenian Hamster IgG1|
|Application||in vitro T cell stimulation/activation, IF, FCM, WB|
|Storage||Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles|
|Sterility||0.2 μM filtered|
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