For research use only. Not for use in humans.

Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo

Clone No.:RB6-8C5

Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo reacts strongly with mouse Ly6G and weakly with mouse Ly6C previously referred to as GR-1. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion.

Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo

Click to purchase the isotype control of Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo

1 Citation

The Nobel Prize

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: Purity: 99% Protein concentration: 10.55 mg/ml Endotoxin Level: <1EU/mg
99

Product Details

Molecular Weight 150 kDa
Clone RB6-8C5
Isotype Rat IgG2b, κ
Application in vivo depletion of Gr-1+ myeloid cells, Flow cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen)
Source CHO
Purification Protein G
Sterility 0.2 μM filtered
Formulation PBS, pH 7.0 Contains no stabilizers or preservatives
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02637986 WITHDRAWN Urinary Tract Infections (UTIs) HaEmek Medical Center, Israel 2022-11-07
NCT05109533 COMPLETED Vaginal Infection; HPV Infection Azienda Ospedaliero, Universitaria Pisana 2018-01-01
NCT03688321 COMPLETED Infection, Bacterial China Medical University Hospital 2018-10-24
NCT04638257 COMPLETED Bacterial Vaginosis The University of Texas Medical Branch, Galveston 2013-01 PHASE1
NCT02150655 COMPLETED Vulvovaginal Candidiasis; Bacterial Vaginosis Western University, Canada 2012-09 EARLY_PHASE1
NCT02021799 COMPLETED Pregnancy Western University, Canada 2012-08

(data from https://clinicaltrials.gov, updated on 2022-11-08)

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