Clone No.:RB6-8C5
Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo reacts strongly with mouse Ly6G and weakly with mouse Ly6C previously referred to as GR-1. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion.
Shimon Sakaguchi
Nature Communications 2025,16, Article number:1325
David Baker
Dev Cell 2023, 58(20):2163-2180.e9.
David Julius
Cell 2017, 185-198.e16
Michael Houghton
Cell Chem Biol, 2020, 27(7):780-792.e5
Charles M. Rice
Cell 2018, 172(3):423-438.e25
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
|---|
| Molecular Weight | 150 kDa |
|---|---|
| Clone | RB6-8C5 |
| Isotype | Rat IgG2b, κ |
| Application | in vivo depletion of Gr-1+ myeloid cells, Flow cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen) |
| Source | CHO |
| Purification | Protein G |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Murine Pathogen Screening Panel | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT02637986 | WITHDRAWN | Urinary Tract Infections (UTIs) | HaEmek Medical Center, Israel | 2022-11-07 | ||
| NCT05109533 | COMPLETED | Vaginal Infection; HPV Infection | Azienda Ospedaliero, Universitaria Pisana | 2018-01-01 | ||
| NCT03688321 | COMPLETED | Infection, Bacterial | China Medical University Hospital | 2018-10-24 | ||
| NCT04638257 | COMPLETED | Bacterial Vaginosis | The University of Texas Medical Branch, Galveston | 2013-01 | PHASE1 | |
| NCT02150655 | COMPLETED | Vulvovaginal Candidiasis; Bacterial Vaginosis | Western University, Canada | 2012-09 | EARLY_PHASE1 | |
| NCT02021799 | COMPLETED | Pregnancy | Western University, Canada | 2012-08 |
(data from https://clinicaltrials.gov, updated on 2022-11-08)
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