The 2.4G2 monoclonal antibody reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. The 2.4G2 antibody is commonly used in flow cytometry staining experiments to prevent non-specific binding of IgG to the FcγIII and FcγII, and possibly FcγI, receptors prior to staining with antigen specific primary antibodies.
Click to purchase the isotype control of Anti-mouse CD16/CD32-InVivo
|Molecular Weight||150 kDa|
|Immunogen||BALB/c mouse macrophage cell line J774|
|Formulation||PBS buffer, pH 7.0|
|Application||in vitro/vivo Fc receptor blocking|
|Storage||Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles|
|Sterility||0.2 μM filtered|
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