Anti-mouse CD25 (IL-2Rα)-InVivo
The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac.The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo.
|Molecular Weight||150 kDa|
|Immunogen||IL-2-dependent cytolytic mouse T cell clone B6.1|
|Formulation||PBS buffer, pH 7.0|
|Application||in vivo regulatory T cell depletion,FCM|
|Storage||Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles|
|Sterility||0.2 μM filtered|
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