Anti-mouse CD25 (IL-2Rα)-InVivo

Catalog No.A2107

The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac.The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo.

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Protocol

Product Details

Molecular Weight 150 kDa
Clone PC-61.5.3
Immunogen IL-2-dependent cytolytic mouse T cell clone B6.1
Formulation PBS buffer, pH 7.0
Isotype Rat IgG1,λ
Application in vivo regulatory T cell depletion,FCM
Storage Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Purification protein A
Sterility 0.2 μM filtered

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID