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Clone No.:9H10
Anti-mouse CTLA-4 (CD152) antibody (Clone:9H10) reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. Anti-mouse CTLA-4 (CD152) antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding.
Shimon Sakaguchi
Nature Communications 2025,16, Article number:1325
David Baker
Dev Cell 2023, 58(20):2163-2180.e9.
David Julius
Cell 2017, 185-198.e16
Michael Houghton
Cell Chem Biol, 2020, 27(7):780-792.e5
Charles M. Rice
Cell 2018, 172(3):423-438.e25
| Molecular Weight | 150 kDa |
|---|---|
| Clone | 9H10 |
| Immunogen | Mouse CTLA-4-human IgG1 fusion protein |
| Isotype | Syrian hamster IgG |
| Application | in vivo/vitro CTLA-4 neutralization, FCM,WB |
| Purification | Protein G |
| Sterility | 0.2 μM filtered |
| Formulation | PBS buffer, pH 7.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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