Clone No.:XT3.11
Anti-mouse TNFα-InVivo reacts with mouse TNFα (tumor necrosis factor-alpha), a multifunctional proinflammatory cytokine. TNFα dysregulation is been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. TNFα knockout animals display defects in response to bacterial infection, characterized by defects in forming organized follicular dendritic cell networks and germinal centers with a lack of primary B cell follicles.
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Molecular Weight | 150 kDa |
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| Clone | XT3.11 |
| Isotype | Rat IgG1 |
| Application | in vitro &in vivo TNFα neutralization, Western blot |
| Source | CHO |
| Purification | Protein G |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 8.0 Contains no stabilizers or preservatives |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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