P2 Receptor

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2855 MRS 2578 <1 mg/mL 42 mg/mL <1 mg/mL
S1984 Ticlopidine HCl 4 mg/mL 1 mg/mL 1 mg/mL
S3737 Cangrelor Tetrasodium 100 mg/mL 2 mg/mL <1 mg/mL
S4637 Prasugrel Hydrochloride <1 mg/mL 46 mg/mL 9 mg/mL
S1258 Prasugrel <1 mg/mL 30 mg/mL 7 mg/mL
S4079 Ticagrelor <1 mg/mL 100 mg/mL 53 mg/mL
S8725 A-804598 <1 mg/mL 63 mg/mL 6 mg/mL
S8519 A-317491 <1 mg/mL 100 mg/mL 100 mg/mL
S7705 A-438079 HCl 61 mg/mL 61 mg/mL 20 mg/mL
S2855 MRS 2578 <1 mg/mL 42 mg/mL <1 mg/mL
S1984 Ticlopidine HCl 4 mg/mL 1 mg/mL 1 mg/mL
S3737 Cangrelor Tetrasodium 100 mg/mL 2 mg/mL <1 mg/mL
S4637 Prasugrel Hydrochloride <1 mg/mL 46 mg/mL 9 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations
S2855

MRS 2578

MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

S1984

Ticlopidine HCl

Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.

S3737New

Cangrelor Tetrasodium

Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.

S4637

Prasugrel Hydrochloride

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

S1258

Prasugrel

Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.

S4079

Ticagrelor

Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.

S8725New

A-804598

A-804598 is a selective P2X7R antagonist with high affinity at rat (IC50 = 10 nM), mouse (IC50 = 9 nM) and human (IC50 = 11 nM) P2X7 receptors.

S8519

A-317491

A-317491 is a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki values of 22 nM and 9 nM for human P2X3 and P2X2/3 receptors.

S7705

A-438079 HCl

A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

S2855

MRS 2578

MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

S1984

Ticlopidine HCl

Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.

S3737New

Cangrelor Tetrasodium

Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.

S4637

Prasugrel Hydrochloride

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.