• Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S3736 Fondaparinux Sodium 100 mg/mL 1 mg/mL <1 mg/mL
S3792 Guggulsterone E&Z -1 mg/mL 62 mg/mL -1 mg/mL
S2782 GW4064 <1 mg/mL 100 mg/mL <1 mg/mL
S2694 Turofexorate Isopropyl (XL335) <1 mg/mL 33 mg/mL 2 mg/mL
S1843 Chenodeoxycholic Acid <1 mg/mL 79 mg/mL 79 mg/mL
S4003 Lithocholic acid <1 mg/mL 75 mg/mL 47 mg/mL
S8733 Tropifexor (LJN452) <1 mg/mL 100 mg/mL <1 mg/mL
S7660 Obeticholic Acid <1 mg/mL 84 mg/mL 84 mg/mL
Catalog No. Information Product Use Citations Product Validations

Fondaparinux Sodium

Fondaparinux is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.


Guggulsterone E&Z

Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist ligands for the bile acid receptor, farnesoid X receptor, and as active ingredients responsible for the hypolipidemic activity.



GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM.


Turofexorate Isopropyl (XL335)

Turofexorate Isopropyl (XL335) is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.


Chenodeoxycholic Acid

Chenodeoxycholic Acid is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines.


Lithocholic acid

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.


Tropifexor (LJN452)

Tropifexor (LJN452) is a novel and highly potent agonist of FXR with EC50 of 0.2 nM in HTRF assay. It shows no significant off-target activity against a broad panel of enzyme, ion channel, nuclear receptor, and GPCR (>10000-fold selectivity for FXR).


Obeticholic Acid

Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM. Phase 3.