• GABAA receptor
  • GABAB receptor

GABAA receptor Selective Activators | Agonists | Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S3663 Afloqualone Afloqualone (AFQ, HQ-495) is a quinazolinone family GABAergic drug with muscle-relaxant and sedative effects, showing the agonist activity at the β subtype of the GABAa receptor. Selective
S5049 Thiocolchicoside Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor. Selective
S3634 6-Hydroxyflavone (6-HF) 6-Hydroxyflavone, a naturally occurring flavonoid, binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors. Selective
S7071 (+)-Bicuculline (+)-Bicuculline (d-Bicuculline) is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. Selective GABAA receptor, IC50: 2 μM
S3786 Glabridin Glabridin (Q-100692, KB-289522, LS-176045), one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory. Selective α1β1γ2 (GABAA receptor), EC50: 17.23 μM; α1β2 (GABAA receptor), EC50: 9.63 μM; α1β3γ2 (GABAA receptor), EC50: 6.83 μM; α1β2γ2 (GABAA receptor), EC50: 6.3 μM
S1329 Etomidate Etomidate (R16659) is a GABAA receptor agonist, used as a short-acting anaesthetic agent or sedative. Selective
S2399 Dihydromyricetin Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Selective
S4494 Methionine Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity. Selective
S4724 Etomidate hydrochloride Etomidate (Amidate, R 16659) hydrochloride is a general anesthetic that produces its effects by enhancing GABA(A) receptor activity. Selective
S1332 Flumazenil (RO 15-1788) Flumazenil (RO 15-1788) is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. Selective
S4197 Bemegride Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning. Selective
S2269 Baicalin (NSC-661431) Baicalin (NSC-661431) is a known prolyl endopeptidase inhibitor and affects the GABA receptors. Selective
S5194 Furosemide sodium Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor. Selective