Methionine

Synonyms: MRX-1024, D-Methionine

Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity.

Methionine Chemical Structure

Methionine Chemical Structure

CAS: 348-67-4

Purity & Quality Control

Batch: S449401 Water] 29 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99.14%
99.14

Methionine Related Products

Choose Selective GABA Receptor Inhibitors

Biological Activity

Description Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity.
Targets
GABAA receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05312372 Withdrawn
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March 2024 Phase 1
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Healthy
The Hospital for Sick Children
January 1 2024 Not Applicable
NCT05514470 Not yet recruiting
Interstitial Lung and Liver Disease|Infantile Liver Failure Syndrome 1|Neurologic Endocrine and Pancreatic Disease Multisystem Infantile-Onset 2|Rajab Interstitial Lung Disease With Brain Calcifications 2
Assistance Publique - Hôpitaux de Paris
April 2023 Not Applicable

Chemical Information & Solubility

Molecular Weight 149.21 Formula

C5H11NO2S

CAS No. 348-67-4 SDF --
Smiles CSCCC(N)C(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 29 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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