ABT-751 (E7010)

For research use only.

Catalog No.S1165

3 publications

ABT-751 (E7010) Chemical Structure

Molecular Weight(MW): 371.41

ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 160 In stock
USD 120 In stock
USD 470 In stock
USD 1570 In stock
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Selleck's ABT-751 (E7010) has been cited by 3 publications

3 Customer Reviews

  • Cell viability in H292 monolayer cells after 3-day treatment and spheroid volume in H292 3D culture after 7-day treatment with ABT751. Data points are means ?SD for three individual experiments. IC50 values were calculated to emphasize the differences in drug potency in 2D verses 3D cultures. ABT751, IC50 of 177.2 ?17.3 nM for 2D and 670.2 ?257.6 nM for 3D.

    Bioorg Med Chem 2013 21, 922-31. ABT-751 (E7010) purchased from Selleck.

    3D spheroid integrity following treatment with ABT751. Representative phase contrast imagines of H292 multi-cellular 3D spheroid at the onset of the treatment and after a 7-day treatment interval with various concentrations. Magnification: 10 X objective, scan bar: 200 μm. Dose and time dependent curves of ABT751 with 3D spheroid assay.

    Bioorg Med Chem 2013 21, 922-31. ABT-751 (E7010) purchased from Selleck.

  • Western blot analysiswas used to validate the regulation of β1-tubulin to vinculin. (A) Inhibited effects of ABT-751 on the β1-tubulin.Washed human plateletswere treatedwith 0, 2.5, 5, 10 and 20 μg/ml ABT-751 for 60 min then stimulated with 0.3 U thrombin (B) Protein expression of vinculin and Talin1 in washed platelets. The representative bands were from different gels for repeated experiments. After densitometric analysis, the values of proteins were normalized against GAPDH, respectively. Data are shown as the mean ± S.D. (n =3-4 per group). ##P < 0.01 vs normal group, **P < 0.01 vs thrombin group, ++P < 0.01 vs thrombin group.

    Fitoterapia, 2017, 116:106-115. ABT-751 (E7010) purchased from Selleck.

Purity & Quality Control

Choose Selective Microtubule Associated Inhibitors

Biological Activity

Description ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.
Features An orally bioavailable tubulin-binding and antimitotic sulfonamide.
Targets
Microtubules [1]
In vitro

In vitro, ABT-751 shows the selective cytotoxicity with IC50 of 0.6–2.6 μM in neuroblastoma and 0.7–4.6 μM in other solid tumor cell lines. Furthermore, ABT-751 also exhibits a selective effect on dynamic microtubules and spares stable microtubules, accounting for the persistence of acetylated and detyrosinated α-tubulin positive polymerized tubules at the IC90 concentration of ABT-751. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HCT-15 cell NH3vV5VRem:uaX\ldoF1cW:wIHHzd4F6 M13jUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iY3;sc44h[2G{Y3nuc41iKEiFVD2xOUBk\WyuIHzpcoUpVUSUKD2pLUwhUUN3ME2wMlM1KM7:TR?= MWCxNVQzPTV|NB?=
HCT116-C9 cell NU[2OIhCTnWwY4Tpc44h[XO|YYm= MkPDSYZn\WO2aY\lJINwdmOnboTyZZRqd25idH:gbY5pcWKrdDDj[YxtKHC{b3zp[oVz[XSrb36gZpkhPTBnIILlcIF1cX[nIITvJJVvfHKnYYTl[EBkd262cn;sJINmdGxiYX\0[ZIhPzJiaIKgc4Yh[2:wdHnueY92eyCneIDvd5Vz\SCrbjDIR3QyOTZvQ{mgZ4VtdCCuaX7lMEBKSzVyPUCuPUDPxE1? MWGxNlM5OzBzNx?=
NCI-H460 cell NGXUSmtRem:uaX\ldoF1cW:wIHHzd4F6 NGn1NldCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIHz1coch[2G{Y3nuc41iKE6FST3IOFYxKGOnbHygcIlv\SBqTVTSLEsqMSxiSVO1NF0xNjN3IN88US=> NHH6W5UyOTR{NUWzOC=>
P388 cell line NGLzfG9HfW6ldHnvckBie3OjeR?= M{LJeFczKGh? NI\sdVJG\m[nY4TpeoUh[2:wY3XueJJifGmxbjD0c{BqdmirYnn0JINmdGxicILvcIln\XKjdHnvckBjgSB3MDWgdoVt[XSrdnWgeI8hfW62cnXheIVlKGOxboTyc4wh[2WubDDh[pRmeiB5MjDodkBw\iClb370bY52d3W|IHX4dI9{fXKnIHnuJHA{QDhiY3XscEBtcW6n78{MJGlEPTB;MD6xPUDPxE1? M37FRVEzOzh|MEG3
P388/4.0 r-M cell line MXTGeY5kfGmxbjDhd5NigQ>? M3\QU|czKGh? NUnBTFhtTW[oZXP0bZZmKGOxbnPlcpRz[XSrb36geI8hcW6qaXLpeEBk\WyuIIDyc4xq\mW{YYTpc44h[nliNUClJJJmdGG2aY\lJJRwKHWwdILlZZRm\CClb370do9tKGOnbHygZYZ1\XJiN{KgbJIhd2ZiY3;ueIlvfW:3czDlfJBwe3W{ZTDpckBROzh6L{SuNEBzNU1iY3XscEBtcW6nLDDJR|UxRTF3IN88US=> NVj5bYpKOTJ|OEOwNVc>
human HL60 cells MVXQdo9tcW[ncnH0bY9vKGG|c3H5 NEnN[2VCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOsJGlEPTB;MD6zOEDPxE1? NFTEVIgyPzJ5NkC1Oi=>
HeLa cells NFzOW2xEgXSxdH;4bYNqfHliYYPzZZk> M1LqPFQ5NTd{IHi= M{X0eGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghfG9iN{KgbJJ{KGK7IGfBWE0yKGG|c3H5MEBKSzVyPUCuNlch|ryP MkPkNlEyOjZyMke=
MDR1 cells MYXDfZRwfG:6aXPpeJkh[XO|YYm= NWfkd5BwPDhvN{KgbC=> NHG3XJZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBPS0lvQVTSMXJGWyCneIDy[ZN{cW6pIF3EVlEh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KFeDVD2xJIF{e2G7LDDJR|UxRTBwMkmg{txO MXOyNVEzPjB{Nx?=
Jurkat cells NXrYcWVOTnWwY4Tpc44h[XO|YYm= NXvxVZE5OjRiaB?= NYDLNIJqS2WubDDjfYNt\SCjcoLld5QhcW5iaIXtZY4hUnW{a3H0JINmdGy|IHHzd4V{e2WmIHHzJIFk[3WvdXzheIlwdiCjdDDHNk9OKHCqYYPlJIFnfGW{IEK0JIhzeyC3c3nu[{Bxem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nJIJ6KE[DQ2OgZY5idHm|aYOsJGlEPTB;MD6xOkDPxE1? Mlm1NlEyOjZyMke=
SW620 cells MkLuR5l1d3SxeHnjbZR6KGG|c3H5 MkLkOFguPzJiaB?= MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjC0PEB1dyB5MjDodpMh[nliV1HUMVEh[XO|YYmsJGlEPTB;MD6xPUDPxE1? NX3KfGRzOjFzMk[wNlc>
A2780 cells MWXDfZRwfG:6aXPpeJkh[XO|YYm= M2PuWVQ5NTd{IHi= NXzK[Y9ZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhPDhidH:gO|IhcHK|IHL5JHdCXC1zIHHzd4F6NCCLQ{WwQVAvOTdizszN MVOyNVEzPjB{Nx?=
HT-29 cells NYPRRmw2WHKxbHnm[ZJifGmxbjDhd5NigQ>? MUG3NkBp NHXJUFZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MD6yNUDPxE1? MUGyN|IxOjh2OR?=
HUVEC MV7GeY5kfGmxbjDhd5NigQ>? MYOxNFAuOTByMDDuUS=> NXfTVXpFPCCq NGLIZY5KdmS3Y4Tpc44hd2ZidnHzZ5Vt[XJiZHnzdpVxfGmwZzDhZ5Rqfmm2eTDpckBJXV[HQzDhd5Nme3OnZDDhd{BXTUeILXnu[JVk\WRidIXi[UBnd3KvYYTpc44h[XRiMUCwJJRwKDFyMECgcm0h[W[2ZYKgOEBpenNiYomgcYlkem:|Y3;wbYMh[W6jbInzbZM> MYCyOFExPjl6Mh?=
H460 cells M4T1bGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWrX[Y1ZPzJiaB?= MkPoR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTFQ3OCClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhdWW2aIns[Y5mKGKudXWgd5RicW6rbnetZoF{\WRiYYPzZZktKEmFNUC9NE4zOTd5IN88US=> Mn7ENlQyODZ7OEK=
MKN45 cells NWjNcWF4S3m2b4TvfIlkcXS7IHHzd4F6 NH;Nd4U4OiCq MnXwR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWtPPDViY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KG2ndHj5cIVv\SCkbIXlJJN1[WmwaX7nMYJie2WmIHHzd4F6NCCLQ{WwQVAvOTZ4IN88US=> Mlq5NlQyODZ7OEK=
HT-29 cells M4OweWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmLWO|IhcA>? MnLIR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KG2ndHj5cIVv\SCkbIXlJJN1[WmwaX7nMYJie2WmIHHzd4F6NCCLQ{WwQVAvOzN6NzFOwG0> NI\qc5gzPDFyNkm4Ni=>
human A549 cells Mm\ER5l1d3SxeHnjbZR6KGG|c3H5 MXS0PEBp MUDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MT6zNUDPxE1? NWr5NWxROjR6M{W3PFY>
ACHN cells MVXDfZRwfG:6aXPpeJkh[XO|YYm= MUW0PEBp NILINY1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCS0iQIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUC9Nk4yOyEQvF2= NFSxSG8zPDh|NUe4Oi=>
MCF7 cells MULDfZRwfG:6aXPpeJkh[XO|YYm= NWLFc2p4PDhiaB?= MV;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MT6yOUDPxE1? MoXmNlQ5OzV5OE[=
HT-29 cells NGHJdotEgXSxdH;4bYNqfHliYYPzZZk> MojMOFghcA>? MW\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyPUGuOlIh|ryP M2LyVFI1QDN3N{i2
A549 cells M3rzVXBzd2yrZnXyZZRqd25iYYPzZZk> M3\1RlI1KGh? MVfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiMkSgbJJ{KGK7IGPSRkBie3OjeTygS2k2OD1zLkOxJO69VQ>? MXyyOVQ3QDB|OR?=
human MCF7 cells MnzlVJJwdGmoZYLheIlwdiCjc4PhfS=> MorFNlQhcA>? M33jPWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjCyOEBpenNiYomgV3JDKGG|c3H5MEBIUTVyPUGuNlUh|ryP MVeyOVQ3QDB|OR?=
KB-S15 cells NF\sN41EgXSxdH;4bYNqfHliYYPzZZk> M2fueFczKGh? M{HrOGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDNVNzNTDj[YxteyCxdnXy[ZhxemW|c3nu[{BRNWeyMUewM21FWiCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nlibXX0bJlt\W6nIHLseYUhe3SjaX7pcocu[mG|ZXSgZZN{[XluIFnDOVA:OC5{ME[g{txO NVfEUmt7OjRzME[5PFI>
KB-7d cells NWHNW2VqS3m2b4TvfIlkcXS7IHHzd4F6 MWC3NkBp M3Xse2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDNTemIHPlcIx{KG:4ZYLlfJBz\XO|aX7nJG1TWCCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nlibXX0bJlt\W6nIHLseYUhe3SjaX7pcocu[mG|ZXSgZZN{[XluIFnDOVA:OC5{MEWg{txO NHjRdFczPDFyNkm4Ni=>
KB-VIN10 cells M{n1SGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mny5O|IhcA>? MVfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRk1XUU5zMDDj[YxteyCxdnXy[ZhxemW|c3nu[{BRNWeyMUewM21FWiCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nlibXX0bJlt\W6nIHLseYUhe3SjaX7pcocu[mG|ZXSgZZN{[XluIFnDOVA:OC5{Mkeg{txO NF\mWJYzPDFyNkm4Ni=>
human PC3 cells NWS4NZkxS3m2b4TvfIlkcXS7IHHzd4F6 NEK3WI01QCCq NHG3fotEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD62NkDPxE1? M1HIPVI3OjRzMEOy
human AsPC1 cells Ml7zR5l1d3SxeHnjbZR6KGG|c3H5 NGPCfWE1QCCq MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBd3BEOSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD12LkGxJO69VQ>? MXiyOlI1OTB|Mh?=
human A549 cells M13MeGN6fG:2b4jpZ4l1gSCjc4PhfS=> MoTsOFghcA>? M3fQ[GN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;NT6zN{DPxE1? MojONlYzPDFyM{K=
Hep3B cells NYG2PZkzS3m2b4TvfIlkcXS7IHHzd4F6 MVi0PEBp NFG1OnREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XB|QjDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlg1KM7:TR?= MYKyOlI1OTB|Mh?=
KB cells NELvXW1EgXSxdH;4bYNqfHliYYPzZZk> NFP1eY04OiCq MmDqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgO|IhcHK|IHL5JI1mfGi7bHXu[UBjdHWnIIP0ZYlvcW6pLXLhd4VlKGG|c3H5MEBKSzVyPUCuNlUyOyEQvF2= NUi0RW1EOjRzME[5PFI>
DU145 cells Mlq5VJJwdGmoZYLheIlwdiCjc4PhfS=> NWfYc3dsOjRiaB?= M{LmVmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgNlQhcHK|IHL5JHNTSiCjc4PhfUwhT0l3ME2xMlgyKM7:TR?= M3jCOVI2PDZ6MEO5
DU145 cells MlfWR5l1d3SxeHnjbZR6KGG|c3H5 M4\ZclQ5KGh? NIPVcIpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBFXTF2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F697zOIFfJOVA:OS56MTFOwG0> MYGyOFg{PTd6Nh?=
human SKBR3 cells MmGxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1\2NVQ5KGh? M2rJNmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNMSlJ|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUC9NE44PCEQvF2= MXmyNlg2ODJzNB?=

... Click to View More Cell Line Experimental Data

In vivo In this Calu-6 xenograft model, ABT-751 as a single agent at 100 and 75 mg/kg/day shows significant antitumor activity, while in combination with cisplatin, ABT-751 shows a dose-dependent enhancement in growth delay. In the HT-29 colon xenograft model, ABT-751 also shows significant antitumor activity as a single agent and produced a dose-dependent enhancement in growth delay In combination with 5-FU. [2] In dogs with lymphoma, ABT-751 exhibits the dose-limiting toxicities that included vomiting, diarrhea, anorexia, or some combination of these with a maximum tolerated dose (MTD) of 350 mg/m2 PO q24h. Furthermore, the mean AUC and Cmax for ABT-751 at the MTD of 350 mg/m2 is 5.55 μg-hour/mL and 0.9 μg/mL, respectively. [3]

Protocol

Cell Research:[1]
- Collapse
  • Cell lines: HOS, HTB-186 Daoy, TC-71, RD, SK-N-AS, SK-N-DZ, LD and KCNR cells
  • Concentrations: 0 to 100 μM
  • Incubation Time: 72 hours
  • Method: Cells, in 1640 RPMI media with FBS, are plated in triplicate onto 96 well tissue culture plates in numbers determined optimal for confluent monolayer growth (5,000 cells/well for HOS, HTB-186 Daoy; 10,000 cells/well for TC-71, RD, SK-N-AS, SK-N-DZ, LD; 30,000 cells/well for KCNR), with an automated, multichannel pipette system. Cells are incubated for 24 hours at 37 °C/5% CO2 then exposed to vehicle control (1.25% DMSO/H2O), VCR (0.1–1000 nM), ABT-751 (0.1 nM–100 μM), and in 4 cell lines (SK-N-AS, KCNR, RD, TC-71) combretastatin (0.1–1000 nM) for 72 hours. Cells are fixed with trichloroacetic acid (final concentration 10%) at 4 °C, washed, then dried at room temperature, stained with SRB in 1% acetic acid and dye is then solubilized with Tris base. Optical density measurements are performed at 540 and 405 nm dual wavelengths in a Bio-Tek EL 340 UV plate reader.
    (Only for Reference)
Animal Research:[2]
- Collapse
  • Animal Models: Calu-6 NSCLC, HT-29 colon, and HCT-116 cells are injected into athymic mice.
  • Dosages: 75 or 100 mg/kg/day
  • Administration: Administered via p.o.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 74 mg/mL (199.24 mM)
Ethanol 12 mg/mL (32.3 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
30% propylene glycol, 5% Tween 80, 65% D5W
For best results, use promptly after mixing.
15 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 371.41
Formula

C18H17N3O4S

CAS No. 141430-65-1
Storage powder
in solvent
Synonyms N/A
Smiles COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O

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Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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