Kaempferol (NSC 407289)

For research use only.

Catalog No.S2314 Synonyms: Robigenin

11 publications

Kaempferol (NSC 407289) Chemical Structure

CAS No. 520-18-3

Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

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Selleck's Kaempferol (NSC 407289) has been cited by 11 publications

1 Customer Review

  • Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).

    Food Funct, 2015, 6(8):2824-33. Kaempferol (NSC 407289) purchased from Selleck.

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Biological Activity

Description Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.
Targets
ERRα [1] ERRγ [1] Topo I [2] fatty acid synthase [3]
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 FS cells NHnB[XdHfW6ldHnvckBie3OjeR?= MYjJcohq[mm2aX;uJI9nKE6RWESg[ZhxemW|c3XkJIlvKEiHS{K5N{BHWyClZXzsd{Bie3Onc4Pl[EBieyCKMl:yJJBzd2S3Y4Tpc44h[nliSELPNk9VgXJxTGDPJIF{e2G7LDDJR|UxRTFwMjFOwG0> MUiyNFc{OTN3Nx?=
human HeLa cells NFfSbYFHfW6ldHnvckBie3OjeR?= M1LIdWlvcGmkaYTpc44hd2ZiTWLQNUB1emGwc3\lZ5Rm\CCrbjDoeY1idiCKZVzhJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiW{PIYWxVSzRidILhcpNxd3K2IHL5JJJieGmmIH\pcJRz[XSrb36gZZN{[XluIFvpQVIvPCEQvF2= NFTGN2EyQTd{NUW3PC=>
human MV4-11 cells M3nibGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUfZcWR2PzJiaB?= MmTlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUXY1NTFzIHPlcIx{KGijcnLvdolv\yCITGSzJI12fGG2aX;uJIFnfGW{IEeyJIhzeyCkeTD0[ZRz[XqxbHn1cUBj[XOnZDDFfkBEgVSxeDDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhT0l3ME2zMlM1KM7:TR?= NHjkS5gzOzRzMUC3Ny=>
MDCK cells NHzFSY9HfW6ldHnvckBie3OjeR?= NVvMbI46UW6qaXLpeIlwdiCxZjDCR3JRKGW6cILld5Nm\CCrbjDNSGNMKGOnbHzzJJV{cW6pIFjv[YNpe3RiM{OzOFIhe3SjaX7pcoctKEmFNUC9OE44KM7:TR?= Mlj6NlE{PTR6MEC=
human MDA-kb2 cells NH\nXmhHfW6ldHnvckBie3OjeR?= NUDZUZNoSW62YXfvcol{fCCjY4Tpeol1gSCjdDDhcoRzd2enbjDy[YNmeHSxcjDpckBpfW2jbjDNSGEuc2J{IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhTEiWLXnu[JVk\WRibIXjbYZmemG|ZTDhZ5Rqfmm2eTDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgZZN{[XluIFnDOVA:QS55IN88US=> M3nhdVE6PTl{MkS1
B16-4A5 cells MkDZSpVv[3Srb36gZZN{[Xl? MoLyTY5pcWKrdHnvckBw\iCvZXzhco9o\W6nc3nzJIlvKHSqZX;wbJltdGmwZT3zeIlufWyjdHXkJI1wfXOnIFKxOk01STViY3XscJMh[W[2ZYKgO|IhcHK|LDDJR|UxRTJyIN88US=> MmWzNVk3OTV7MUC=
human HL60 cells M2LCPWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmnBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGw3OCClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJN2en[rdnHsJIF1KDVyIIXNJIFnfGW{IEeyJIhzeyCkeTDDR2s5KGG|c3H5 NX7kb|ZwOjVyN{S4NVU>
mouse 3T3L1 cells M1z6NGZ2dmO2aX;uJIF{e2G7 MkfyTY5pcWKrdHnvckBw\iCDTWDLMY1m\GmjdHXkJIFlcXCxY4n0[UBlcW[oZYLlcpRq[XSrb36gbY4hdW:3c3WgN3Q{VDFiY3XscJM> NWrIcJFMOjB6MkK5NFI>
mouse RAW264.7 cells NFfIbnhHfW6ldHnvckBie3OjeR?= NU\6[4lVSW62aXnu[oxidW2jdH;yfUBi[3Srdnn0fUBqdiCOUGOtd5RqdXWuYYTl[EBud3W|ZTDSRXczPjRwNzDj[YxteyCjc4Pld5Nm\CCjczDubZRzcXSnIHzleoVtKGG2IEGgeI8hOTByIIXNJIFnfGW{IEK0JIhzeyCkeTDHdolme3NibXX0bI9l M1HLUFIyOzV|NUSz
mouse L929 cells MWTGeY5kfGmxbjDhd5NigQ>? NHnKeYRKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIGTOSk1idHCqYT3pcoR2[2WmIHP5eI91d3irY3n0fUBw\iCvb4Xz[UBNQTJ7IHPlcIx{KGG|c3Xzd4VlKGG|IIP1dpZqfmGuaYT5JJRz\WG2ZXSge4l1cCCmcoXnJIFnfGW{IEKgbJJ{KG:oIGTOSoFteGijIITy[YF1dWWwdB?= M2LIXVkzQDd2MUW=
human U87 cells MUXDfZRwfG:6aXPpeJkh[XO|YYm= M3jhTlUuPDBizszN MVy3NkBp Mn;ER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWVg4KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjdDC1JJRwKDRyIIXNJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYm= NUfOOWR[OjJ6N{GyNVc>
human A549 cells MorVR5l1d3SxeHnjbZR6KGG|c3H5 MVW1MVQxKM7:TR?= NX3tfnNbPzJiaB?= MmPRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 NGDCWIMzOjh5MUKxOy=>
human MCF7 cells NUe1c|ZmS3m2b4TvfIlkcXS7IHHzd4F6 NGLHZoc2NTRyIN88US=> NGGzTlU4OiCq Mm\4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 MWWyNlg4OTJzNx?=
MDA-MB-231 cells MoX3R5l1d3SxeHnjbZR6KGG|c3H5 NF\uemY2NTRyIN88US=> M4LsZVczKGh? NX:zbmpRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVI{OSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 Ml\0NlI5PzF{MUe=
MDCK cells M1\lNGZ2dmO2aX;uJIF{e2G7 MVq1NEDPxE1? MX7BcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDpcoZtfWWwenGgRUB3cXK3czDINW4yKEFxUGKvPE8{PCCrbn\lZ5Rm\CCrbjDNSGNMKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDmcJVwemW|Y3XuZ4UheG:|aYTpeoUh[2WubIOgZZQhPTBidV2gbY1ufW6xZnz1c5Jme2OnbnPlJIF{e2G7 MoHYNVk4Ojl|MU[=
human NCI-H2126 cells NX2wcnhSS3m2b4TvfIlkcXS7IHHzd4F6 MUG1MVQxKM7:TR?= MWK3NkBp NV\tN3U5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVkOLLViyNVI3KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjdDC1JJRwKDRyIIXNJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYm= NXTXbHlmOjJ6N{GyNVc>
human SMMC7721 cells NH:4VoxEgXSxdH;4bYNqfHliYYPzZZk> NWTSPYxPPS12MDFOwG0> MUi3NkBp M1O0T2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNOVUN5N{KxJINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBifCB3IITvJFQxKHWPIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[Xl? NGrEO4YzOjh5MUKxOy=>
human PANC1 cells MUTDfZRwfG:6aXPpeJkh[XO|YYm= NE\wSGs2NTRyIN88US=> MmPkO|IhcA>? NGHuVZJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSU6FMTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NX3zeos2OjJ6N{GyNVc>
human BxPC3 cells MWHDfZRwfG:6aXPpeJkh[XO|YYm= NYW2PHZuPS12MDFOwG0> MVq3NkBp NFrjTnFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDgFCFMzDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NGDEVFczOjh5MUKxOy=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 57 mg/mL warmed (199.14 mM)
Ethanol 3 mg/mL (10.48 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage powder
in solvent
Synonyms Robigenin
Smiles C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID