Kaempferol

Catalog No.S2314 Synonyms: Robigenin

Kaempferol Chemical Structure

Molecular Weight(MW): 286.23

Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

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Cited by 5 Publications

1 Customer Review

  • Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).

    Food Funct, 2015, 6(8):2824-33. Kaempferol purchased from Selleck.

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Biological Activity

Description Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.
Targets
ERRα [1] ERRγ [1] Topo I [2] fatty acid synthase [3]
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 FS cells NUHVS|RZTnWwY4Tpc44h[XO|YYm= M1uzOmlvcGmkaYTpc44hd2ZiTl;YOEBmgHC{ZYPz[YQhcW5iSFXLNlk{KE[VIHPlcIx{KGG|c3Xzd4VlKGG|IFiyU|IheHKxZIXjeIlwdiCkeTDINm8zN1S7cj;MVG8h[XO|YYmsJGlEPTB;MT6yJO69VQ>? MX2yNFc{OTN3Nx?=
human HeLa cells NWn1emtsTnWwY4Tpc44h[XO|YYm= MoqyTY5pcWKrdHnvckBw\iCPUmCxJJRz[W6|ZnXjeIVlKGmwIHj1cYFvKEinTHGgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCdM1jdUHREPCC2cnHud5BwenRiYomgdoFxcWRiZnnseJJifGmxbjDhd5NigSxiS3m9Nk41KM7:TR?= M2\ie|E6PzJ3NUe4
human MV4-11 cells NIfHd5hEgXSxdH;4bYNqfHliYYPzZZk> NH3LN|A4OiCq Ml[3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUXY1NTFzIHPlcIx{KGijcnLvdolv\yCITGSzJI12fGG2aX;uJIFnfGW{IEeyJIhzeyCkeTD0[ZRz[XqxbHn1cUBj[XOnZDDFfkBEgVSxeDDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhT0l3ME2zMlM1KM7:TR?= NUmye3JvOjN2MUGwO|M>
MDCK cells NXvoVFBYTnWwY4Tpc44h[XO|YYm= MXPJcohq[mm2aX;uJI9nKEKFUmCg[ZhxemW|c3XkJIlvKE2GQ1ugZ4VtdHNidYPpcochUG:nY3jzeEA{OzN2MjDzeIFqdmmwZzygTWM2OD12Lkeg{txO NHHxSmEzOTN3NEiwNC=>
human MDA-kb2 cells Mn;HSpVv[3Srb36gZZN{[Xl? M1TYUGFvfGGpb37pd5Qh[WO2aY\peJkh[XRiYX7kdo9o\W5icnXj[ZB1d3JiaX6gbJVu[W5iTVTBMYtjOiClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJGRJXC2rbnT1Z4VlKGy3Y3nm[ZJie2ViYXP0bZZqfHliYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCLQ{WwQVkvPyEQvF2= M{HLNlE6PTl{MkS1
B16-4A5 cells NYnJNVZSTnWwY4Tpc44h[XO|YYm= NX;kcVhLUW6qaXLpeIlwdiCxZjDt[Yxidm:pZX7ld4l{KGmwIITo[Y9xcHmubHnu[U1{fGmvdXzheIVlKG2xdYPlJGIyPi12QUWgZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyPUKwJO69VQ>? M1WyZVE6PjF3OUGw
human HL60 cells MWXDfZRwfG:6aXPpeJkh[XO|YYm= NYrIem0yS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKGG2IEWwJJVOKGGodHXyJFczKGi{czDifUBES0t6IHHzd4F6 MoDTNlUxPzR6MUW=
mouse 3T3L1 cells MkLySpVv[3Srb36gZZN{[Xl? MlvFTY5pcWKrdHnvckBw\iCDTWDLMY1m\GmjdHXkJIFlcXCxY4n0[UBlcW[oZYLlcpRq[XSrb36gbY4hdW:3c3WgN3Q{VDFiY3XscJM> Mn[yNlA5OjJ7MEK=
mouse RAW264.7 cells MnTmSpVv[3Srb36gZZN{[Xl? M{L4[WFvfGmrbn\sZY1u[XSxcomgZYN1cX[rdImgbY4hVFCVLYP0bY12dGG2ZXSgcY92e2ViUlHXNlY1NjdiY3XscJMh[XO|ZYPz[YQh[XNibnn0dol1\SCuZY\lcEBifCBzIITvJFExOCC3TTDh[pRmeiB{NDDodpMh[nliR4Lp[ZN{KG2ndHjv[C=> M1;C[lIyOzV|NUSz
mouse L929 cells NIrE[JpHfW6ldHnvckBie3OjeR?= MYHJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKFSQRj3hcJBp[S2rbnT1Z4VlKGO7dH;0c5hq[2m2eTDv[kBud3W|ZTDMPVI6KGOnbHzzJIF{e2W|c3XkJIF{KHO3co\peoFtcXS7IITy[YF1\WRid3n0bEBlenWpIHHmeIVzKDJiaILzJI9nKFSQRnHsdIhiKHS{ZXH0cYVvfA>? NWexT|FtQTJ6N{SxOS=>
human U87 cells MoG4R5l1d3SxeHnjbZR6KGG|c3H5 MmrUOU01OCEQvF2= M1ziWVczKGh? MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDVPFch[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGG2IEWgeI8hPDBidV2gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeR?= NGfBN3kzOjh5MUKxOy=>
human A549 cells NVXlVoZ4S3m2b4TvfIlkcXS7IHHzd4F6 MXq1MVQxKM7:TR?= Mln5O|IhcA>? NVv6cJZCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 M3HoR|IzQDdzMkG3
human MCF7 cells NVznOHF1S3m2b4TvfIlkcXS7IHHzd4F6 NFzCfoI2NTRyIN88US=> M4jFPVczKGh? NYXlV|VLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NUPFfJE4OjJ6N{GyNVc>
MDA-MB-231 cells MUXDfZRwfG:6aXPpeJkh[XO|YYm= MnW3OU01OCEQvF2= MYG3NkBp Mne4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[XRiNTD0c{A1OCC3TTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7 MV2yNlg4OTJzNx?=
MDCK cells M1H1VWZ2dmO2aX;uJIF{e2G7 MonnOVAh|ryP MW\BcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDpcoZtfWWwenGgRUB3cXK3czDINW4yKEFxUGKvPE8{PCCrbn\lZ5Rm\CCrbjDNSGNMKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDmcJVwemW|Y3XuZ4UheG:|aYTpeoUh[2WubIOgZZQhPTBidV2gbY1ufW6xZnz1c5Jme2OnbnPlJIF{e2G7 MkHpNVk4Ojl|MU[=
human NCI-H2126 cells MUPDfZRwfG:6aXPpeJkh[XO|YYm= NI\z[G02NTRyIN88US=> NVW2Z2I3PzJiaB?= M1XSNWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KMkGyOkBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[XRiNTD0c{A1OCC3TTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7 NHHv[2EzOjh5MUKxOy=>
human SMMC7721 cells MUPDfZRwfG:6aXPpeJkh[XO|YYm= NFTsbHA2NTRyIN88US=> MoDVO|IhcA>? MmXVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV21OSzd5MkGgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIF1KDVidH:gOFAhfU1iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigQ>? MYqyNlg4OTJzNx?=
human PANC1 cells MXPDfZRwfG:6aXPpeJkh[XO|YYm= NUHRWXREPS12MDFOwG0> MlniO|IhcA>? NHLVOFhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSU6FMTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NV7Ud45ROjJ6N{GyNVc>
human BxPC3 cells NE\LRoREgXSxdH;4bYNqfHliYYPzZZk> MXS1MVQxKM7:TR?= MnrwO|IhcA>? MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCfHBEOyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 MVOyNlg4OTJzNx?=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 57 mg/mL warmed (199.14 mM)
Ethanol 3 mg/mL (10.48 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage powder
in solvent
Synonyms Robigenin

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID