Kaempferol

Catalog No.S2314 Synonyms: Robigenin

Kaempferol Chemical Structure

Molecular Weight(MW): 286.23

Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

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Cited by 2 Publications

1 Customer Review

  • Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).

    Food Funct, 2015, 6(8):2824-33. Kaempferol purchased from Selleck.

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Biological Activity

Description Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.
Targets
ERRα [1] ERRγ [1] Topo I [2] fatty acid synthase [3]
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 FS cells MonmSpVv[3Srb36gZZN{[Xl? MU\Jcohq[mm2aX;uJI9nKE6RWESg[ZhxemW|c3XkJIlvKEiHS{K5N{BHWyClZXzsd{Bie3Onc4Pl[EBieyCKMl:yJJBzd2S3Y4Tpc44h[nliSELPNk9VgXJxTGDPJIF{e2G7LDDJR|UxRTFwMjFOwG0> MYeyNFc{OTN3Nx?=
human HeLa cells NIPReHpHfW6ldHnvckBie3OjeR?= NWXRO2xQUW6qaXLpeIlwdiCxZjDNVnAyKHS{YX7z[oVkfGWmIHnuJIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDbN2heVFSFNDD0doFve3CxcoSgZpkhemGyaXSg[oltfHKjdHnvckBie3OjeTygT4k:Oi52IN88US=> NXnlfHJUOTl5MkW1O|g>
human MV4-11 cells NEnVcmhEgXSxdH;4bYNqfHliYYPzZZk> NGriblY4OiCq NH[xUGlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOXjRvMUGgZ4VtdHNiaHHyZo9zcW6pIF\MWFMhdXW2YYTpc44h[W[2ZYKgO|IhcHK|IHL5JJRmfHKjen;sbZVuKGKjc3XkJGV7KEO7VH;4JINmdGxidnnhZoltcXS7IHHzd4F6NCCJSUWwQVMvOzRizszN NEfsRYczOzRzMUC3Ny=>
MDCK cells MnfRSpVv[3Srb36gZZN{[Xl? MYLJcohq[mm2aX;uJI9nKEKFUmCg[ZhxemW|c3XkJIlvKE2GQ1ugZ4VtdHNidYPpcochUG:nY3jzeEA{OzN2MjDzeIFqdmmwZzygTWM2OD12Lkeg{txO M{DQe|IyOzV2OECw
human MDA-kb2 cells NV:0cZhLTnWwY4Tpc44h[XO|YYm= Mo\IRY51[WexbnnzeEBi[3Srdnn0fUBifCCjbnTyc4dmdiC{ZXPldJRweiCrbjDoeY1idiCPRFGtb4IzKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gSGhVNWmwZIXj[YQhdHWlaX\ldoF{\SCjY4Tpeol1gSCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEmFNUC9PU44KM7:TR?= MlLyNVk2QTJ{NEW=
B16-4A5 cells M4X6PWZ2dmO2aX;uJIF{e2G7 MWnJcohq[mm2aX;uJI9nKG2nbHHuc4dmdmW|aYOgbY4hfGinb4DofYxtcW6nLYP0bY12dGG2ZXSgcY92e2ViQkG2MVRCPSClZXzsd{Bi\nSncjC3NkBpenNuIFnDOVA:OjBizszN Mnf0NVk3OTV7MUC=
human HL60 cells NFnidlhEgXSxdH;4bYNqfHliYYPzZZk> M{\WcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhNPjBiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB{fXK4aY\hcEBifCB3MDD1UUBi\nSncjC3NkBpenNiYomgR2NMQCCjc4PhfS=> MUWyOVA4PDhzNR?=
mouse 3T3L1 cells MkfsSpVv[3Srb36gZZN{[Xl? MXLJcohq[mm2aX;uJI9nKEGPUFutcYVlcWG2ZXSgZYRqeG:leYTlJIRq\m[ncnXueIlifGmxbjDpckBud3W|ZTCzWFNNOSClZXzsdy=> NYDCVlFbOjB6MkK5NFI>
mouse RAW264.7 cells MkPuSpVv[3Srb36gZZN{[Xl? MWHBcpRqcW6obHHtcYF1d3K7IHHjeIl3cXS7IHnuJGxRWy2|dHnteYxifGWmIH3veZNmKFKDV{K2OE44KGOnbHzzJIF{e2W|c3XkJIF{KG6rdILpeIUhdGW4ZXygZZQhOSC2bzCxNFAhfU1iYX\0[ZIhOjRiaILzJIJ6KEe{aXXzd{Bu\XSqb3S= NGXiZmQzOTN3M{W0Ny=>
mouse L929 cells M3j5UmZ2dmO2aX;uJIF{e2G7 NF;RXFZKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIGTOSk1idHCqYT3pcoR2[2WmIHP5eI91d3irY3n0fUBw\iCvb4Xz[UBNQTJ7IHPlcIx{KGG|c3Xzd4VlKGG|IIP1dpZqfmGuaYT5JJRz\WG2ZXSge4l1cCCmcoXnJIFnfGW{IEKgbJJ{KG:oIGTOSoFteGijIITy[YF1dWWwdB?= NH\K[JE6Ojh5NEG1
human U87 cells MljtR5l1d3SxeHnjbZR6KGG|c3H5 M{jqXFUuPDBizszN NXfBbIw4PzJiaB?= MW\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDVPFch[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGG2IEWgeI8hPDBidV2gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeR?= MYCyNlg4OTJzNx?=
human A549 cells MVfDfZRwfG:6aXPpeJkh[XO|YYm= MkPnOU01OCEQvF2= MmXZO|IhcA>? NXvMXoJZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NWmzNXFSOjJ6N{GyNVc>
human MCF7 cells M2jnSGN6fG:2b4jpZ4l1gSCjc4PhfS=> MmPPOU01OCEQvF2= NYC4R4FKPzJiaB?= NIj1OllEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDheEA2KHSxIESwJJVOKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZk> MVWyNlg4OTJzNx?=
MDA-MB-231 cells MX;DfZRwfG:6aXPpeJkh[XO|YYm= MVS1MVQxKM7:TR?= NUPHbWJWPzJiaB?= NXvVclVQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVI{OSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 MnHBNlI5PzF{MUe=
MDCK cells NGq0TI1HfW6ldHnvckBie3OjeR?= M1ziVFUxKM7:TR?= NWP5b4hwSW62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhcW6obIXlcppiKEFidnnyeZMhUDGQMTDBM3BTNzhxM{SgbY5n\WO2ZXSgbY4hVUSFSzDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h\my3b4Lld4NmdmOnIIDvd4l1cX[nIHPlcIx{KGG2IEWwJJVOKGmvbYXuc4ZtfW:{ZYPj[Y5k\SCjc4PhfS=> MUWxPVczQTNzNh?=
human NCI-H2126 cells NVn2fZA2S3m2b4TvfIlkcXS7IHHzd4F6 MnHhOU01OCEQvF2= MUm3NkBp MlL5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh{MUK2JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBifCB3IITvJFQxKHWPIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[Xl? MmTxNlI5PzF{MUe=
human SMMC7721 cells NWmwWJdRS3m2b4TvfIlkcXS7IHHzd4F6 M2PFbFUuPDBizszN M2\uWlczKGh? NHOzZnNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUVU2FN{eyNUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[XRiNTD0c{A1OCC3TTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7 MkG1NlI5PzF{MUe=
human PANC1 cells M4nVZWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVjuV2hNPS12MDFOwG0> MWe3NkBp M{n5c2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBCVkNzIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDheEA2KHSxIESwJJVOKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZk> M{\DZ|IzQDdzMkG3
human BxPC3 cells NX;UXW4zS3m2b4TvfIlkcXS7IHHzd4F6 M1\KUVUuPDBizszN M{jjTFczKGh? NVj1PGNPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSniSQ{OgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIF1KDVidH:gOFAhfU1iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigQ>? M{nvOVIzQDdzMkG3

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 57 mg/mL warmed (199.14 mM)
Ethanol 3 mg/mL (10.48 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage powder
in solvent
Synonyms Robigenin

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID