Kaempferol

For research use only.

Catalog No.S2314 Synonyms: Robigenin

6 publications

Kaempferol Chemical Structure

Molecular Weight(MW): 286.23

Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

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Selleck's Kaempferol has been cited by 6 publications

1 Customer Review

  • Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).

    Food Funct, 2015, 6(8):2824-33. Kaempferol purchased from Selleck.

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Biological Activity

Description Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.
Targets
ERRα [1] ERRγ [1] Topo I [2] fatty acid synthase [3]
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 FS cells NYTZOZFQTnWwY4Tpc44h[XO|YYm= NHzoUGJKdmirYnn0bY9vKG:oIF7PXFQh\XiycnXzd4VlKGmwIFjFT|I6OyCIUzDj[YxteyCjc4Pld5Nm\CCjczDINm8zKHC{b3T1Z5Rqd25iYomgTFJQOi:WeYKvUHBQKGG|c3H5MEBKSzVyPUGuNkDPxE1? NFrUfYozODd|MUO1Oy=>
human HeLa cells MXLGeY5kfGmxbjDhd5NigQ>? NULJfXJlUW6qaXLpeIlwdiCxZjDNVnAyKHS{YX7z[oVkfGWmIHnuJIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDbN2heVFSFNDD0doFve3CxcoSgZpkhemGyaXSg[oltfHKjdHnvckBie3OjeTygT4k:Oi52IN88US=> M2DBRVE6PzJ3NUe4
human MV4-11 cells NF3M[pVEgXSxdH;4bYNqfHliYYPzZZk> MmS3O|IhcA>? MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNWlQuOTFiY3XscJMhcGG{Yn;ybY5oKE[OVEOgcZV1[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IITleJJigm:uaYXtJIJie2WmIFX6JGN6XG:6IHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBIUTVyPUOuN|Qh|ryP MX2yN|QyOTB5Mx?=
MDCK cells NEXWO2VHfW6ldHnvckBie3OjeR?= NGrKc|FKdmirYnn0bY9vKG:oIFLDVnAh\XiycnXzd4VlKGmwIF3ER2sh[2WubIOgeZNqdmdiSH;lZ4h{fCB|M{O0NkB{fGGrbnnu[{whUUN3ME20Mlch|ryP MWWyNVM2PDhyMB?=
human MDA-kb2 cells MoPqSpVv[3Srb36gZZN{[Xl? M3K1cGFvfGGpb37pd5Qh[WO2aY\peJkh[XRiYX7kdo9o\W5icnXj[ZB1d3JiaX6gbJVu[W5iTVTBMYtjOiClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJGRJXC2rbnT1Z4VlKGy3Y3nm[ZJie2ViYXP0bZZqfHliYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCLQ{WwQVkvPyEQvF2= M4O4UFE6PTl{MkS1
B16-4A5 cells MkD3SpVv[3Srb36gZZN{[Xl? MUfJcohq[mm2aX;uJI9nKG2nbHHuc4dmdmW|aYOgbY4hfGinb4DofYxtcW6nLYP0bY12dGG2ZXSgcY92e2ViQkG2MVRCPSClZXzsd{Bi\nSncjC3NkBpenNuIFnDOVA:OjBizszN M3rWN|E6PjF3OUGw
human HL60 cells NIHkcVlEgXSxdH;4bYNqfHliYYPzZZk> NW\id5VES3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKGG2IEWwJJVOKGGodHXyJFczKGi{czDifUBES0t6IHHzd4F6 MnfqNlUxPzR6MUW=
mouse 3T3L1 cells NGPtVnVHfW6ldHnvckBie3OjeR?= NHfwRmtKdmirYnn0bY9vKG:oIFHNVGsudWWmaXH0[YQh[WSrcH;jfZRmKGSrZn\ldoVvfGmjdHnvckBqdiCvb4Xz[UA{XDOOMTDj[Yxtew>? MWKyNFgzOjlyMh?=
mouse RAW264.7 cells NYC4flg5TnWwY4Tpc44h[XO|YYm= NHPaOmJCdnSraX7mcIFudWG2b4L5JIFkfGm4aYT5JIlvKEySUz3zeIlufWyjdHXkJI1wfXOnIGLBW|I3PC55IHPlcIx{KGG|c3Xzd4VlKGG|IH7peJJqfGVibHX2[Ywh[XRiMTD0c{AyODBidV2gZYZ1\XJiMkSgbJJ{KGK7IFfybYV{eyCvZYToc4Q> M{\POlIyOzV|NUSz
mouse L929 cells NFHMdVRHfW6ldHnvckBie3OjeR?= NVu0bJpPUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDUUmYu[WyyaHGtbY5lfWOnZDDjfZRwfG:6aXPpeJkhd2ZibX;1d4UhVDl{OTDj[YxteyCjc4Pld5Nm\CCjczDzeZJ3cX[jbHn0fUB1emWjdHXkJJdqfGhiZIL1[{Bi\nSncjCyJIhzeyCxZjDUUmZidHCqYTD0doVifG2nboS= NHLmTlU6Ojh5NEG1
human U87 cells MlnsR5l1d3SxeHnjbZR6KGG|c3H5 NHfxWJk2NTRyIN88US=> MUK3NkBp M2nQPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHU5PyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 MlnGNlI5PzF{MUe=
human A549 cells MlLIR5l1d3SxeHnjbZR6KGG|c3H5 Mn\2OU01OCEQvF2= MVq3NkBp MWXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjdDC1JJRwKDRyIIXNJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYm= NFuz[IszOjh5MUKxOy=>
human MCF7 cells M4LMT2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXr4blNLPS12MDFOwG0> Mn63O|IhcA>? NEGxdGVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDheEA2KHSxIESwJJVOKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZk> MXWyNlg4OTJzNx?=
MDA-MB-231 cells M3vVXGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVy1MVQxKM7:TR?= NFK1OHE4OiCq Mn7TR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[XRiNTD0c{A1OCC3TTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7 MVWyNlg4OTJzNx?=
MDCK cells M4nkN2Z2dmO2aX;uJIF{e2G7 MkHYOVAh|ryP M4XrXmFvfGm4aYLhcEBi[3Srdnn0fUBi\2GrboP0JIlv\my3ZX76ZUBCKH[rcoXzJGgyVjFiQT;QVk85NzN2IHnu[oVkfGWmIHnuJG1FS0tiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJIZtfW:{ZYPj[Y5k\SCyb4PpeIl3\SClZXzsd{BifCB3MDD1UUBqdW23bn;mcJVwemW|Y3XuZ4Uh[XO|YYm= M1\wUVE6PzJ7M{G2
human NCI-H2126 cells MUnDfZRwfG:6aXPpeJkh[XO|YYm= MWW1MVQxKM7:TR?= NFPoRmg4OiCq MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDOR2kuUDJzMk[gZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIF1KDVidH:gOFAhfU1iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigQ>? MnPmNlI5PzF{MUe=
human SMMC7721 cells NEm1R5dEgXSxdH;4bYNqfHliYYPzZZk> MVe1MVQxKM7:TR?= M1m3SFczKGh? NHy1eYZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUVU2FN{eyNUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[XRiNTD0c{A1OCC3TTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7 MoPwNlI5PzF{MUe=
human PANC1 cells MmO1R5l1d3SxeHnjbZR6KGG|c3H5 MkHZOU01OCEQvF2= Mne2O|IhcA>? M2jLSGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBCVkNzIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDheEA2KHSxIESwJJVOKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZk> MlfaNlI5PzF{MUe=
human BxPC3 cells M2fO[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NEnHNI42NTRyIN88US=> M4Tob|czKGh? MnrRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRphRSzNiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHH0JFUhfG9iNECgeW0h[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfS=> NH[4NW0zOjh5MUKxOy=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 57 mg/mL warmed (199.14 mM)
Ethanol 3 mg/mL (10.48 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage powder
in solvent
Synonyms Robigenin
Smiles OC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID