New PDE Inhibitors

Catalog No. Product Name Information
E2983 PF-04957325 PF-04957325 is a highly potent and selective inhibitor of PDE8, with IC50 values of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively. PF-04957325 greatly potentiates steroidogenesis in wild type adrenal cells.
E1382 BI 1015550 BI 1015550 is an orally active inhibitor of PDE4B with IC50 of 7.2 nM. It has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD).
S0424 HA130 HA130 is a selective autotaxin (ATX) inhibitor with IC50 of 28 nM.
All PDE Inhibitors